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Initial Investigation of Preclinical Integrated SPECT and MR Imaging

Mark J. Hamamura, Seunghoon Ha, Werner W. Roeck, Douglas J. Wagenaar, Dirk Meier, Bradley E. Patt, Orhan Nalcioglu
2010 Technology in Cancer Research and Treatment  
MRI data were utilized for attenuation correction (AC) of the nuclear projection data and optimized Wiener filtering of the SPECT reconstruction for improved image accuracy.  ...  In this study, we utilized a dual modality SPECT/MRI (MRSPECT) system to investigate the integration of SPECT and MRI for improved image accuracy.  ...  Yuting Lin for their assistance in setting up the animal experiment.  ... 
doi:10.1177/153303461000900103 pmid:20082527 pmcid:PMC4235993 fatcat:27knvqdjdzdw3ej7h3kht7b2zm

Parallelization of iterative reconstruction algorithms in multiple modalities

Debasis Mitra, Hui Pan, Fares Alhassen, Youngho Seo
2014 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)  
pinholes SPECT, and cone-bean CT data.  ...  [1]; (2) MLEM for parallel-hole SPECT with computation of point spread function embedded (implemented in CUDA C++) [2]; and (3) an OSEM version for parallel-hole SPECT.  ...  Acknowledgments This work is supported in part by National Institute of Biomedical Imaging and Bioengineering under grant #R01 EB012965.  ... 
doi:10.1109/nssmic.2014.7430944 pmid:27081300 pmcid:PMC4829380 fatcat:2mouofn6qbgkjkp2j6m7qgf4yu

Image reconstruction algorithm for a spinning strip CZT SPECT camera with a parallel slat collimator and small pixels

Gengsheng L. Zeng, Daniel Gagnon
2004 Medical Physics (Lancaster)  
This paper discusses the use of small pixels in a spinning CdZnTe single photon emission computed tomography (SPECT) camera that is mounted with a parallel slat collimator.  ...  In order to acquire a complete data set the tilted-slat collimator must spin 360°at each SPECT view while the proposed design requires only 180°at each SPECT view.  ...  to derive an exact reconstruction algorithm.  ... 
doi:10.1118/1.1813873 pmid:15651629 fatcat:khqc7iaibbcnzeeamzbz7acqp4

A hardware investigation of robotic SPECT for functional and molecular imaging onboard radiation therapy systems

Susu Yan, James Bowsher, MengHeng Tough, Lin Cheng, Fang-Fang Yin
2014 Medical Physics (Lancaster)  
The robot inherent coordinate frames could be an effective means to estimate detector pose for use in SPECT image reconstruction. C  ...  Results: The robotic SPECT system was able to maneuver parallel-hole and pinhole collimated SPECT detectors in close proximity to the phantom, minimizing impact of the flat-top couch on detector radius  ...  Log-sensitivity vs resolution for pinhole and parallel-hole detectors over the range of RORs utilized during the SPECT scans. Each point corresponds to an ROR at which data were acquired.  ... 
doi:10.1118/1.4898121 pmid:25370663 pmcid:PMC4209015 fatcat:rey63vlicrbjzifczxefyxv2aa

180° Pinhole SPET with a tilted detector and OS-EM reconstruction: phantom studies and potential clinical applications

Alain Seret, Michel Defrise, Didier Blocklet
2001 European Journal of Nuclear Medicine and Molecular Imaging  
This study investigated the feasibility of OS-EM reconstruction of pinhole SPECT acquired with a tilted detector head and a 180° orbit.  ...  Phantom and patient data have been recorded using a standard single head camera. Reconstructions have been performed using a dedicated OS-EM algorithm.  ...  In both cases, SPECT with an ultra high resolution parallel hole collimator (UHR SPECT) has also been recorded and reconstructed with OS-EM for parallel geometry in order to evaluate the clinical improvement  ... 
doi:10.1007/s002590100629 pmid:11734923 fatcat:nxqvt5o5lvdcjg67z6fycgotze

New hardware, new software, different results: The estimation of left ventricular volumes and ejection fractions with gated myocardial perfusion SPECT

Mark F. Smith
2018 Journal of Nuclear Cardiology  
With a look toward the acquisition and image reconstruction parameters in Table 2 in 1 , one can make an effort to try to understand the possible influence of various factors on EDV, ESV and LVEF.  ...  For both IQ-SPECT and conventional acquisition and image reconstruction the Quantitative Gated SPECT (QGS; Cedars-Sinai) software package 5 was used to process the reconstructed gated cardiac perfusion  ...  For example, the projection data acquired with the parallel hole collimator could be reconstructed with an iterative method with and without modeling of depth-dependent collimator response.  ... 
doi:10.1007/s12350-018-01523-9 pmid:30446940 fatcat:v2gbg7vqsrhjtnnwojmjcwzzl4

Attenuation correction for rotating slant-hole (RSH) SPECT using exact rebinning

J. Wagner, F. Noo, R. Clackdoyle, G. Bal, P. Christian
2003 IEEE Transactions on Nuclear Science  
Exponential data were obtained from the measured projections, with an effective attenuation value of pc = O.l2/cm.  ...  We immediately observe that the reconstruction from the ideal isolated noise-free heart data (experiment (a)) shows excellent uniformity and no sign of attenuation artifacts.  ... 
doi:10.1109/tns.2002.807872 fatcat:fxklnuizhjfqnlyih3cejqe3pa

A novel approach to multipinhole SPECT for myocardial perfusion imaging

Tobias Funk, Dennis L Kirch, John E Koss, Elias Botvinick, Bruce H Hasegawa
2006 Journal of Nuclear Medicine  
techniques using parallel-hole collimation.  ...  However, conventional rotational SPECT suffers from prolonged study times because of relatively low detection efficiency.  ...  This work is also supported by a Bioengineering Research Partnership award from the National Institute of Biomedical Imaging and Bioengineering, by National Institutes of Health (NIH) grant 8 R01 EB00348  ... 
pmid:16595492 fatcat:grx5m5h5ijeehfzmsgvs6onwpu

Estimation of 6-Degree-of-Freedom (6-DOF) Rigid-Body Patient Motion from Projection Data by the Principal-Axes Method in Iterative Reconstruction

Bing Feng, Michael A. King
2006 2006 IEEE Nuclear Science Symposium Conference Record  
To evaluate our method, we simulated an acquisition of the MCAT phantom with a 3-head SPECT system and imaged the Data Spectrum anthropomorphic phantom on a 3-head IRIX SPECT system.  ...  For both the MCAT phantom simulations and anthropomorphic phantom experiment, the motion-present data were reconstructed with 10 iterations of the OSEM which estimates and corrects the motion as described  ...  The contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health.  ... 
doi:10.1109/nssmic.2006.356436 pmid:24817766 pmcid:PMC4013124 fatcat:gsdhyfefvzcsney3cv4swnczru

Analytical compensation for spatially variant detector response in SPECT with varying focal-length fan-beam collimators

Tianfang Li, Junhai Wen, Zhengrong Liang
2003 IEEE Transactions on Nuclear Science  
In this method, the deblurred projection is explicitly expressed as an integral of the collimator blurred data and the fully calibrated system kernel matrix with certain transforms.  ...  This method also represents a unified framework for detector response compensation in parallel-hole fan-beam and VFF SPECT with a circular scan orbit.  ...  Research efforts have been made for parallel-beam SPECT [15] .  ... 
doi:10.1109/tns.2003.812440 fatcat:tebqipnmmjenhbgg3gxrzfqqyy

Integration of advanced 3D SPECT modeling into the open-source STIR framework

Berta Marti Fuster, Carles Falcon, Charalampos Tsoumpas, Lefteris Livieratos, Pablo Aguiar, Albert Cot, Domenec Ros, Kris Thielemans
2013 Medical Physics (Lancaster)  
Figure 5 5 shows an example of each reconstructed data: axial view of Data Spectrum torso phantom (left), maximum intensity projection (MIP) image of the bone SPECT data (middle) and axial view of the  ...  CONCLUSIONS In this work an extension of a PET reconstruction library to SPECT has been presented using simulated and acquired data from scanners of different manufacturers.  ... 
doi:10.1118/1.4816676 pmid:24007178 fatcat:shrkpjfu6zewbl6itbfgofud6u

Total Variation Regularization for Edge Preserving 3D SPECT Imaging in High Performance Computing Environments [chapter]

L. Antonelli, L. Carracciuolo, M. Ceccarelli, L. D'Amore, A. Murli
2002 Lecture Notes in Computer Science  
Here, we focus on development of mathematical software on high performance architectures for Total Variation based regularization reconstruction of 3D SPECT images.  ...  Clinical diagnosis environments often require the availability of processed data in real-time, unfortunately, reconstruction times are prohibitiveonconventional computers, neither the adoption of expensive  ...  which the quality of the reconstruction degrades, such optimal number of iterations being typically chosen with experimentation, depending on the amount of noise and the kind of images.  ... 
doi:10.1007/3-540-46080-2_18 fatcat:pxpmfpmfdve3bbqzahlfhgb4wy

Implementation of sensitivity and resolution modeling for SPECT with cone-beam collimator

Andrzej Krol, Vikram R. Kunniyur, Wei Lee, Kedar R. Gangal, Ioana L. Coman, Edward D. Lipson, Deborah A. Karczewski, F. Deaver Thomas, David H. Feiglin, J. Michael Fitzpatrick, Joseph M. Reinhardt
2005 Medical Imaging 2005: Image Processing  
We obtained CBC SPECT scans of a physical point source phantom, Defrise phantom and a female patient, and investigated performance of our algorithm.  ...  We analyzed axial and transaxial profiles obtained for Defrise phantom and evaluated the reconstructed breast SPECT patient images.  ...  Experimental data points were obtained with a cone-beam collimator (f-70 cm): solid line.We reconstructed parallel-beam SPECT and cone-beam SPECT of Defrise phantom.  ... 
doi:10.1117/12.596273 dblp:conf/miip/KrolKLGCLKTF05 fatcat:n7s75umt75hplimvwdfp73jhby

Development of a small animal SPECT imager with LYSO scintillator arrays and PSPMTs

Qiushi Zhang, Suying Li, Zhaoheng Xie, Yanye Lu, Kun Yang, Qiushi Ren
2013 The 6th 2013 Biomedical Engineering International Conference  
The preliminary results demonstrate that this SPECT imager can achieve the small animal whole body imaging effectively and thus be one of the modalities of our future multimodality imaging system.  ...  ., Ltd., Shizuoka Prefecture, Japan), and a parallel hole collimator (Nuclear Fields Pty.  ...  A phantom (a conical bottle filled with 99m Tc, Fig. 4 ) was used to evaluate the correction of the reconstructed image data, but it left an air bubble.  ... 
doi:10.1109/bmeicon.2013.6687648 fatcat:uzs3vututbaozhnyrirkgikmge

A SPECT Scanner for Rodent Imaging Based on Small-Area Gamma Cameras

Eduardo Lage, José L. Villena, Gustavo Tapias, Naira P. Martinez, Maria L. Soto-Montenegro, Mónica Abella, Alejandro Sisniega, Francisco Pino, Domènec Ros, Javier Pavia, Manuel Desco, Juan J. Vaquero
2010 IEEE Transactions on Nuclear Science  
to an in-house developed data acquisition system.  ...  We developed a cost-effective SPECT scanner prototype (rSPECT) for in vivo imaging of rodents based on small-area gamma cameras.  ...  Pinhole and Parallel-Hole SPECT Reconstruction Analytical and statistical algorithms were used for image reconstruction.  ... 
doi:10.1109/tns.2010.2057516 fatcat:w2g4fkxp2jcwzk4tk33inj7xfe
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