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An approach for Ewing test selection to support the clinical assessment of cardiac autonomic neuropathy
2013
Artificial Intelligence in Medicine
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In this paper, we use data mining methods to find optimal sequences of tests for the clinical risk assessment of cardiac autonomic neuropathy (CAN), prepare outcomes required for determination of optimal ...
Conclusion We have applied decision trees to the problem of supporting clinicians in finding optimal sequences of tests for each individual patient for the assessment of cardiac autonomic neuropathy. ...
doi:10.1016/j.artmed.2013.04.007
pmid:23768975
fatcat:2om7tbssyjfqnhdjhgxbxrexqa
Machine Learning Methods for Automated Detection of Severe Diabetic Neuropathy
2016
Journal of Diabetic Complications & Medicine
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Severe diabetic neuropathy represents a significant neurological problem in diabetes as it requires urgent intervention to reduce the risk of sudden cardiac death. ...
This method is intended to enhance the effectiveness of the diagnosis of severe diabetic neuropathy. ...
Acknowledgement The authors wish to acknowledge the technical assistance of Bev de Jong and Paul Reidler for collecting the Ewing data. ...
doi:10.4172/2475-3211.1000108
fatcat:5udibzc5jbdtxpwrvz5idexqmi
Noninvasive exploration of Cardiac Autonomic Neuropathy by heart rate and blood pressure variability analysis in Type 2 Diabetic patients
2021
Pakistan Journal of Medical Sciences
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To determine the prevalence of asymptomatic cardiac autonomic neuropathy and its association with risk factors among patients with Type-2 diabetes mellitus (T2DM). ...
After taking medical history and demographics, Cardiac Autonomic Neuropathy (CAN) was identified by using Ewing's cardiac autonomic reflex tests (CARTs) and association of risk factors was also investigated ...
Source of funding: Self-financed. ...
doi:10.12669/pjms.37.4.3675
pmid:34290776
pmcid:PMC8281166
fatcat:q7u4ptnr6vcsboe6bhbvx2nf3a
The detection of early myocardial changes in asymptomatic diabetic individuals by 99mTc – Myoview gated-SPET and heart rate variability measurement
2014
Bratislava Medical Journal
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In the present study, we examined diabetic patients without a history of cardiovascular disease with negative treadmill test and no signs of systolic dysfunction for presence of cardiac autonomic neuropathy ...
Diagnosis of cardiac autonomic neuropathy based on Ewing´s testing and HRV examination was established in 60 % of T1DM patients (p=0.001) and 77 % of T2DM patients (p=0.001). ...
According to the current guidelines of European Society of Cardiology, a positive SPET fi nding without clinical or ECG signs of subendocardial ischemia is not an indication for selective coronary angiography ...
doi:10.4149/bll_2014_045
fatcat:wouq7h3x6faxpg6hulydmywj6u
Heartbeat and arrhythmia perception in diabetic autonomic neuropathy
1991
Psychological Medicine
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In the subjects with diabetic autonomic neuropathy, the spontaneaus variability and stress-induced reactivity of the heart rate as weil as the number of tachycardic episodes were reduced, whereas the frequency ...
Cardiac perception disordersalso playavital roJe in other clinical problems, e.g. silent myocardial infarction and Iack of awareness of hypoglycaemia in diabetes mellitus. ...
Cardiac perception in diabetic autonomic neuropathy was assessed with a hea t (mental) tracking task and an arrhythmi r beat ception task. ...
doi:10.1017/s0033291700020523
fatcat:ct6sdsgirne4hgu4n75unxtoha
Sudden cardiac death in diabetes mellitus: risk factors in the Rochester diabetic neuropathy study
2005
Journal of Neurology, Neurosurgery and Psychiatry
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Objectives: To determine risk factors for sudden cardiac death and the role of diabetic autonomic neuropathy (DAN) in the Rochester diabetic neuropathy study (RDNS) Methods: Associations between diabetic ...
Medical records, death certificates, and necropsy reports were assessed for causes of sudden cardiac death. Results: 21 cases of sudden cardiac death were identified over 15 years of follow up. ...
The database from the RDNS has been used to develop and assess neuropathy tests, composite scores, and a staging approach, 9 the prevalence of diabetic complications, 8 progression, 10 and risk factors ...
doi:10.1136/jnnp.2004.039339
pmid:15654040
pmcid:PMC1739480
fatcat:kl4ypgxjsncglp5atdiukmz2pa
Identifying diabetic patients with cardiac autonomic neuropathy by heart rate complexity analysis
2009
BioMedical Engineering OnLine
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Early sub clinical detection of CAN and intervention are of prime importance for risk stratification in preventing sudden death due to silent myocardial infarction. ...
Cardiac autonomic neuropathy (CAN) in diabetes has been called a "silent killer", because so few patients realize that they suffer from it, and yet its effect can be lethal. ...
Acknowledgements This work was partially supported by an Australian Research Council (ARC) Linkage grant (LP0454378) awarded to MP and an early career grant awarded to AHK by University of Melbourne. ...
doi:10.1186/1475-925x-8-3
pmid:19178728
pmcid:PMC2645418
fatcat:at6ipoda3bffdjwviriw4md6he
Exercise based assessment of cardiac autonomic function in type 1 versus type 2 diabetes mellitus
2020
Cardiology Journal
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Cardiac autonomic neuropathy (CAN) is a complication of diabetes mellitus (DM) that is associated with increased mortality. ...
The variable pathophysiology for exercise-induced autonomic abnormalities in type 1 versus type 2 DM may impact prognosis. ...
Subjects with diabetes had no clinical evidence of peripheral or autonomic neuropathy and had low overall scores on CAN testing (Ewing score 0.8 ± 0.8 for type 1 DM and 1.2 ± 0.9 for type 2 DM, p = NS) ...
doi:10.5603/cj.a2020.0064
pmid:32378730
pmcid:PMC9007477
fatcat:kvelrwme25aojeb674rpvodqzi
Cardiac Autonomic Neuropathy in Diabetes: A clinical perspective
2010
Diabetes Care
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A clinical perspective RODICA POP-BUSUI, MD, PHD T his review covers the epidemiology, pathophysiology, clinical presentation, and diagnosis of cardiac autonomic neuropathy (CAN) in diabetes and discusses ...
current evidence on approaches to prevention and treatment of CAN. ...
the clinical assessment of CAN in the future. ...
doi:10.2337/dc09-1294
pmid:20103559
pmcid:PMC2809298
fatcat:uk6udqq24ncgjnor3uhztskua4
Screening cardiovascular autonomic neuropathy in diabetic patients with microvascular complications using machine learning: a 24-hour heart rate variability study
2021
IEEE Access
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The approach is considered to be simple and effective, especially for under-resourced clinical settings. ...
Cardiovascular autonomic neuropathy (CAN) is one of the most overlooked complications associated with diabetes. ...
The current gold standard approach to diagnose and assess CAN patients is to perform five Ewing cardiac reflex tests [12] . ...
doi:10.1109/access.2021.3107687
fatcat:wpesjnf6jzhojk26lqqkkanx2e
Cardiac Autonomic Neuropathy in Diabetes Mellitus
2018
Methodist DeBakey Cardiovascular Journal
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Clinical manifestations range from orthostasis to myocardial infarction. The diagnosis is made using multiple autonomic function tests to assess both sympathetic and parasympathetic function. ...
Cardiovascular autonomic neuropathy (CAN) is a severely debilitating yet underdiagnosed condition in patients with diabetes. ...
As clinical CAN progresses, orthostatic hypotension becomes apparent. 5, 18, 20 The standard CARTs may be used to obtain an autonomic neuropathy score to assess the severity of CAN and monitor its progression ...
doi:10.14797/mdcj-14-4-251
pmid:30788010
pmcid:PMC6369622
fatcat:uxgut4mje5eldlgofa4tdu36f4
Diabetic Autonomic Neuropathy
2003
Diabetes Care
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Cardiovascular autonomic neuropathy (CAN) is the most studied and clinically important form of DAN. ...
A complete workup for erectile dysfunction in men should include history (medical and sexual); psychological evaluation; hormone levels; measurement of nocturnal penile tumescence; tests to assess penile ...
In all 15 studies, the baseline assessment for cardiovascular autonomic function was made on the basis of one or more of the tests described by Ewing et al. (95) . ...
doi:10.2337/diacare.26.5.1553
pmid:12716821
fatcat:avkdtwvgubbjzm2rxb3al27zfq
The prevalence of cardiac autonomic neuropathy in prediabetes: a systematic review
2020
Diabetologia
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Aims/hypothesis Cardiac autonomic neuropathy (CAN) is independently associated with silent myocardial ischaemia, major cardiovascular events, myocardial dysfunction and cardiovascular mortality. ...
Six of the selected studies reported definite CAN prevalence data (9–39%). ...
Acknowledgements We would like to acknowledge staff at the Edge Hill University Library, Clinical Sciences Centre, Aintree University Hospital for their support. ...
doi:10.1007/s00125-020-05316-z
pmid:33164108
pmcid:PMC7801295
fatcat:x57ljrufazeuvoecmgjuqjav2e
The ECG Vertigo in Diabetes and Cardiac Autonomic Neuropathy
2011
Experimental Diabetes Research
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In this paper, the clinical and research value of the ECG is readdressed in diabetes and in the presence of cardiac autonomic neuropathy. ...
The ECG offers a quick, noninvasive clinical and research screen for the early detection of cardiovascular disease in diabetes. ...
Diagnostics Tests for the Assessment of Cardiac Autonomic Neuropathy The Golden Standard in clinical autonomic testing remains the cardiovascular reflex tests. ...
doi:10.1155/2011/687624
pmid:21747831
pmcid:PMC3124253
fatcat:nh2jeekrfjfyfcvs3lqzjhhzo4
Diabetic Cardiovascular Autonomic Neuropathy
2007
Circulation
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Advances in technology, built on decades of research and clinical testing, now make it possible to objectively identify early stages of CAN with the use of careful measurement of autonomic function and ...
of the most overlooked of all serious complications of diabetes is cardiovascular autonomic neuropathy (CAN), 1-3 which encompasses damage to the autonomic nerve fibers that innervate the heart and blood ...
In all 15 studies, the baseline assessment for cardiovascular autonomic function was made on the basis of 1 or more of the tests described by Ewing et al. 35 Total mortality rates were higher in subjects ...
doi:10.1161/circulationaha.106.634949
pmid:17242296
fatcat:35po7dsz5vb7lblw6vaygcdlky
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