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An agent-based model of dengue virus transmission shows how uncertainty about breakthrough infections influences vaccination impact projections
2019
PLoS Computational Biology
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Our goal in this study was to quantify the extent to which uncertainty about breakthrough infections results in uncertainty about vaccination impact, with a focus on vaccines for dengue. ...
To realistically account for the many forms of heterogeneity in dengue virus (DENV) transmission, which could have implications for the dynamics of indirect protection, we used a stochastic, agent-based ...
Acknowledgments This research made extensive use of computing resources provided by the Center for Research Computing at the University of Notre Dame.
Author Contributions Conceptualization: T. ...
doi:10.1371/journal.pcbi.1006710
pmid:30893294
pmcid:PMC6443188
fatcat:xbbpspz7svc6np4mzpnwvqf2ra
Vaccines and Antivirals: Grand Challenges and Great Opportunities
2021
Frontiers in Virology
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The virus infected about one-third of the planet's population (∼500 million people at that time) and made an estimated 50 million victims. ...
Zoonotic viruses may show limited variability in their natural hosts; however, these viruses have the potential to infect humans (an immunological naïve population). ...
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...
doi:10.3389/fviro.2021.666548
fatcat:qth6e42pe5d2vmjuwprvj3oidu
Projections of zoster incidence in Australia based on demographic and transmission models of varicella-zoster virus infection
2017
Vaccine
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Title: Projections of zoster incidence in Australia based on demographic and transmission models of varicella-zoster virus infection Other name/s: Faculty: Medicine Varicella Zoster Virus (VZV) firstly ...
However, following age-standardisation, HZ trends showed an increase of 8.11% over the same period. ...
How demographic changes in the Australian population have influenced the epidemiology of varicella infection over the 20 th century and 2. How these changes could impact on HZ epidemiology. ...
doi:10.1016/j.vaccine.2017.09.090
pmid:29050801
fatcat:xre5obpv5zdcpeaaqm3pdndxlu
ISAR News
2019
Antiviral Research
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This collective, deliberative and collaborative methodology can be not only enriching in the implementation of strategies, but it is also an efficient way to triangulate research techniques and strategies ...
to obtain more solid results and broader consensus, in this case, on priorities in the field of vector control of AA in this region. ...
What is the focus of your research now?
Belgium during your Postdoc. Could you please tell us about this experience and how your stay abroad influenced your career? ...
doi:10.1016/s0166-3542(18)30746-0
fatcat:esn5r75mbzevthf3xyec3uuuti
SEVERE COINFECTIONS OF DENGUE AND PANDEMIC INFLUENZA A H1N1 VIRUSES
2010
The Pediatric Infectious Disease Journal
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, An. koliensis, An. farauti s.s., An. farauti 4 and An. hinesorum (formerly An 1
SPATIAL SCALE OF DENGUE VIRUS TRANSMISSION IN IQUITOS, PERU Kelly A. ...
We studied the dynamics of both virus replication when dengue-2 virus (DENV-2) and yellow fever virus vaccine strain 17D (YFV-17D) infected the same culture of mammalian cells (Vero cells). ...
The results demonstrated an exacerbation of the parasitism in infected mice, as result of the immunosuppressive chemical agent activity during the course of infection by T. cruzi. ...
doi:10.1097/inf.0b013e3181e6c69b
pmid:20811315
pmcid:PMC5614439
fatcat:h764ud7zjnamlprplnjdogffza
Abstracts for Supplement
2010
International Journal of Infectious Diseases
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Travel medicine has emerged as a new field of medicine, moving to an evidence based body of knowledge concerning risk assessment and measures to protect the health of travellers. ...
All will influence travelers' health and pose new challenges to travel medicine in the forthcoming decades. ...
Background: A combination of geographical features makes Mongolia an ideal location for understanding the epidemiology of avian influenza viruses in wild birds. ...
doi:10.1016/j.ijid.2010.02.003
fatcat:quufwjql2ncdtdtcqhyspvncaa
Zika e Aedes aegypti: antigos e novos desafios
2017
História, Ciências, Saúde: Manguinhos
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O objetivo deste texto é identificar esse impacto e as mudanças históricas, sociais e sanitárias da doença e o legado do vírus zika. ...
I've been amazed at how many rumors have circulated in Brazil about zika, relating the disease to vaccines, the use of insecticides and pesticides. ...
How do you see the zika epidemic impacting on the debate about contraception and maternal and infant health? ...
doi:10.1590/s0104-59702017000500017
pmid:29412263
fatcat:6rd6mxytkfddhkdfc2u2pmx3oa
Evolution and public health
2009
Proceedings of the National Academy of Sciences of the United States of America
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sources of exposures to infectious agents and chemicals, diverse causes of migration of populations, and climate change. ...
The substrate for the study of evolution in public health includes international patterns of incidence and prevalence of disease, influences of human and animal behavior, dramatic changes in diet, environmental ...
(28) have created a community-based vaccine ontology to standardize vaccine annotation, integrate information about vaccine types, and support computer-assisted reasoning (www.violinet.org/vaccineontology ...
doi:10.1073/pnas.0906198106
pmid:19966311
pmcid:PMC2868289
fatcat:kmqzrqtobfahvhxzw4l23xctgy
Communicable Diseases
[chapter]
2014
The New Public Health
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An official apology was subsequently rendered to the government of Guatemala. ...
The US Presidential Commission on Bioethics has highlighted this case as an awakener to ensure that something of this magnitude, grossly violating the rights of study participants, is never repeated. ...
Studies showing equivocal benefit of BCG in preventing TB have added to the dispute and uncertainty. ...
doi:10.1016/b978-0-12-415766-8.00004-5
fatcat:o7bowmzvf5ch3anp3qyrz3xzxi
Statistical physics of vaccination
2016
Physics reports
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To help reduce their impact, mathematical models of disease transmission have been studied to help understand disease dynamics and inform prevention strategies. ...
Vaccination - one of the most important preventive measures of modern times - is of great interest both theoretically and empirically. ...
infected agent could influence more neighbors. ...
doi:10.1016/j.physrep.2016.10.006
fatcat:hxq7di4j4zfilfv3m4ogbkzovu
Fast detection of Southern tomato virus by one-step transcription loop-mediated isothermal amplification (RT-LAMP)
2017
Journal of Virological Methods
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together with dengue virus. ...
However,little attention has been devoted in many cases to the possible impact of mixed infections on the transmission of viruses by their natural vector organisms. ...
To perform an exhaustive study of the effect of size (or generations) of a battery of polyanionic carbosilane dendrimers (PCDs) containing a polyphenolic core for the prevention of HIV-1 transmission as ...
doi:10.1016/j.jviromet.2016.12.004
pmid:27965036
fatcat:5vqbhusk7vajhkvtl7wkufo2na
Infectious disease epidemiology
[chapter]
2015
Teaching Epidemiology
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Working group TS057 "Sexual risk behavior having an impact on blood donor management". Chair: Rut Norda (Sweden) ...
agents such as hepatitis E
virus, hantavirus, leptospirosis, and vector-borne pathogens (e.g., Borrelia burgdorferi,
Plasmodium species, Dengue virus, West Nile virus). ...
for a transmission modelling project(2012-14, rotavirus transmission). ...
doi:10.1093/acprof:oso/9780199685004.003.0016
fatcat:olecp4fdzvdi3orrnnqusbbs6i
Infectious disease epidemiology
[chapter]
2010
Teaching Epidemiology
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Working group TS057 "Sexual risk behavior having an impact on blood donor management". Chair: Rut Norda (Sweden) ...
agents such as hepatitis E
virus, hantavirus, leptospirosis, and vector-borne pathogens (e.g., Borrelia burgdorferi,
Plasmodium species, Dengue virus, West Nile virus). ...
for a transmission modelling project(2012-14, rotavirus transmission). ...
doi:10.1093/acprof:oso/9780199239481.003.016
fatcat:6wcltfzcifacjjwoc3lorblabq
Infectious Disease Epidemiology
1996
American Journal of Epidemiology
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Working group TS057 "Sexual risk behavior having an impact on blood donor management". Chair: Rut Norda (Sweden) ...
agents such as hepatitis E
virus, hantavirus, leptospirosis, and vector-borne pathogens (e.g., Borrelia burgdorferi,
Plasmodium species, Dengue virus, West Nile virus). ...
for a transmission modelling project(2012-14, rotavirus transmission). ...
doi:10.1093/aje/144.supplement_8.s34
pmid:8857840
fatcat:6x5ban3wr5fshanwarosanwjwq
Infectious Disease Epidemiology
[chapter]
2014
Handbook of Epidemiology
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Working group TS057 "Sexual risk behavior having an impact on blood donor management". Chair: Rut Norda (Sweden) ...
agents such as hepatitis E
virus, hantavirus, leptospirosis, and vector-borne pathogens (e.g., Borrelia burgdorferi,
Plasmodium species, Dengue virus, West Nile virus). ...
for a transmission modelling project(2012-14, rotavirus transmission). ...
doi:10.1007/978-0-387-09834-0_34
fatcat:moiem6wgpjcjfmk62aoxhgkl7i
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