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Does single-source create an added value? Evaluating the impact of introducing x4T into the clinical routine on workflow modifications, data quality and cost–benefit

Philipp Bruland, Christian Forster, Bernhard Breil, Sonja Ständer, Martin Dugas, Fleur Fritz
2014 International Journal of Medical Informatics  
into the routine patient care documentation workflow with respect to process modifications, data quality and execution times in patient care as well as research documentation.  ...  Methods: We analyzed the documentation workflow of routine patient care and research documentation in the medical field of pruritus to identify redundant and error-prone process steps.  ...  Acknowledgements We want to acknowledge Sebastian Balhorn, Inga-Marlena Höben, and Emely Verweyen for the data acquisition as well as Gottfried Vossen for the support in the joint project. Katja  ... 
doi:10.1016/j.ijmedinf.2014.08.007 pmid:25220487 fatcat:npmwgndt2vh57flky4ykyiyd7e

EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases

Sophia von Martial, Tobias J. Brix, Luisa Klotz, Philipp Neuhaus, Klaus Berger, Clemens Warnke, Sven G. Meuth, Heinz Wiendl, Martin Dugas, Orhan Aktas
2019 PLoS ONE  
Standardizing routine documentation can enable secondary use for medical research.  ...  The aim of this work is to develop, implement and evaluate a minimal core dataset in routine health care with a focus on secondary use as case study for NIDs.  ...  Antje Echterhoff from the Department of Neurology of the University Hospital Münster for providing data elements of the neuroinflammatory biobank.  ... 
doi:10.1371/journal.pone.0223886 pmid:31613917 pmcid:PMC6793844 fatcat:c762yl3r3rcgfahexh2hb3mkea

Clinical research informatics: a conceptual perspective

M. G. Kahn, C. Weng
2012 JAMIA Journal of the American Medical Informatics Association  
We present a conceptual model based on an informatics-enabled clinical research workflow, integration across heterogeneous data sources, and core informatics tools and platforms.  ...  We use this conceptual model to highlight 18 new articles in the JAMIA special issue on clinical research informatics.  ...  The bottom portion in figure 1 highlights the major core research topics in CRI, including secondary use of clinical data for research, distributed queries, data integration, record linkage, data quality  ... 
doi:10.1136/amiajnl-2012-000968 pmid:22523344 pmcid:PMC3392857 fatcat:5zg7tavwubh4bpowo563pcn5ja

ProjectFlow: a configurable workflow management application for point of care research

Rupali Dhond, Danne Elbers, Nilla Majahalme, Svitlana Dipietro, Sergey Goryachev, Ryan Acher, Sarah Leatherman, Tori Anglin-Foote, Qingzhu Liu, Shaoyu Su, Ramana Seerapu, Robert Hall (+5 others)
2021 JAMIA Open  
It has also helped us evaluate over 3800 patients for recruitment and enroll over 370 of them into RePOP for use in data sharing partnerships and predictive analytics aimed at optimizing cancer treatment  ...  Results As of January 2021, ProjectFlow has facilitated management of study recruitment, enrollment, randomization, and drug orders for over 10 000 patients for the DCP clinical trial.  ...  CONCLUSION POC-R aims to integrate research processes within day-to-day clinical operations and utilize patient EHR data for study recruitment, monitoring, and outcome reporting.  ... 
doi:10.1093/jamiaopen/ooab074 pmid:34485848 pmcid:PMC8411372 fatcat:3muco44sw5bkfjoovmnd2k5udu

A Methodology to Perform Semi-automatic Distributed EHR Database Queries

Olga Fajarda, Luis Bastião Silva, Peter R. Rijnbeek, Michel Van Speybroeck, José Luis Oliveira
2018 Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies  
The exploration of these electronic health records (EHRs) is essential for clinical and pharmaceutical research and, therefore, solutions for secure sharing of information across different databases are  ...  The proliferation of electronic health databases has resulted in the existence of a wide collection of diversified clinical digital data.  ...  Beyond the undeniable value that EHRs have for the direct health care of patients, i.e. beyond primary clinical care, the secondary use of these data brings great benefit to scientific, clinical and translational  ... 
doi:10.5220/0006579701270134 dblp:conf/biostec/FajardaSRSO18 fatcat:vs5etekbpjdqrafx3wvnvxkuvy

Development of electronic medical records for clinical and research purposes: the breast cancer module using an implementation framework in a middle income country- Malaysia

Nurul Aqilah Mohd Nor, Nur Aishah Taib, Marniza Saad, Hana Salwani Zaini, Zahir Ahmad, Yamin Ahmad, Sarinder Kaur Dhillon
2019 BMC Bioinformatics  
Advances in medical domain has led to an increase of clinical data production which offers enhancement opportunities for clinical research sector.  ...  We believe that integration of multiple clinical visit data sources provides a more comprehensive, accurate and real-time update of clinical data to be used for epidemiological studies and audits.  ...  Availability of data and materials The EMR data cannot be made public due to Personal Data Protection Act policies.  ... 
doi:10.1186/s12859-018-2406-9 pmid:30717675 pmcid:PMC7394320 fatcat:xtlsv2n3ojb2jgrmxong5itl4i

An architecture of Multiagent System (MAS) for healthcare Intelligent Decision Support System (IDSS)

N Mahiddin, Z.A. Othman, A.A. Bakar
2018 Journal of Fundamental and Applied Sciences  
An example, a medical data on patient's blood pressure is related to the patient's age. A different category of age has a different level of normal blood pressure.  ...  Consequently, this paper focus on the healthcare workflow and proposed a CARE concept with MAS technology to be as a solution for the problems elligent Decision Support System Research Article Special  ...  In general, the VEPR has been developed for data retrieval and integration using the JADE framework as a multiagent system platform [7] .  ... 
doi:10.4314/jfas.v9i5s.12 fatcat:2uqh2ygmlbak3ipcpkwjhnc5pa

Implementing Single Source: The STARBRITE Proof-of-Concept Study

R. Kush, L. Alschuler, R. Ruggeri, S. Cassells, N. Gupta, L. Bain, K. Claise, M. Shah, M. Nahm
2007 JAMIA Journal of the American Medical Informatics Association  
In this proof-of-concept study, we examine the feasibility of using point-of-care data capture for both the medical record and clinical research in the setting of a working clinical trial.  ...  We hypothesized that by doing so, we could increase reuse of patient data, eliminate redundant data entry, and minimize disruption to clinic workflow.  ...  An Integrating the Healthcare Enterprise (IHE) profile was demonstrated within various commercial EHR systems for five use cases (entering data once for secondary or reuse downstream): clinical research  ... 
doi:10.1197/jamia.m2157 pmid:17600107 pmcid:PMC1975790 fatcat:rzik37csorap5idrwoljswvu7e

Secondary Use of Patients' Electronic Records (SUPER): An Approach for Meeting Specific Data Needs of Clinical and Translational Researchers

Evan T Sholle, Joseph Kabariti, Stephen B Johnson, John P Leonard, Jyotishman Pathak, Vinay I Varughese, Curtis L Cole, Thomas R Campion
2018 AMIA Annual Symposium Proceedings  
Academic medical centers commonly approach secondary use of electronic health record (EHR) data by implementing centralized clinical data warehouses (CDWs).  ...  We hypothesized that an approach that aggregates raw data from source systems, ignores initial modeling typical of CDWs, and transforms raw data for specific research purposes would meet investigator needs  ...  We thank Rajesh Bollapragada for help in conceptualizing the institutional setting, and Monika Ahuja for developing and describing some of the methodologies that support SUPER.  ... 
pmid:29854228 pmcid:PMC5977622 fatcat:lltocwvbhvef3j3ebn6nzbdxfe

Shiny FHIR: An Integrated Framework Leveraging Shiny R and HL7 FHIR to Empower Standards-Based Clinical Data Applications

Na Hong, Naresh Prodduturi, Chen Wang, Guoqian Jiang
2017 Studies in Health Technology and Informatics  
We designed two primary workflows that integrate a series of R packages to enable both patient-centered and cohort-based interactive analyses.  ...  In this study, we describe our efforts in building a clinical statistics and analysis application platform using an emerging clinical data standard, HL7 FHIR, and an open source web application framework  ...  Paul Kingsbury for his help with language editing.  ... 
pmid:29295223 pmcid:PMC5939961 fatcat:totmg7vfmvckzaeiwijyr6blwi

The effect of embedding "smart" disease coding within routine workflow on electronic medical record disease recording: A prospective single arm trial. (Preprint)

Dee Mangin, Jennifer Lawson, Krzysztof Adamczyk, Dale Guenter
2019 JMIR Medical Informatics  
The intervention was integrated as part of usual clinical workflow during routine billing activities.  ...  Incomplete data and poor consistency of coded disease values within EMR problem lists are widespread issues that limit primary and secondary uses of these data.  ...  Acknowledgments The authors would like to thank the primary care clinicians and patients of the MUSIC PBRN who contribute their data to the network through which the study data were generated and willingly  ... 
doi:10.2196/16764 pmid:32716304 fatcat:xwsjrzodo5etrds6ozp7oytxma

Integrating research data capture into the electronic health record workflow: real-world experience to advance innovation

Marsha Laird-Maddox, Susan B Mitchell, Mark Hoffman
2014 Perspectives in health information management  
Historically, for patients enrolled in clinical research trials or studies, data have been documented in the medical record, and then study-related data are manually reentered into an electronic case report  ...  Past efforts to integrate EHRs and research systems for the purposes of data capture have demonstrated that interoperability is possible.  ...  Acknowledgements We would like to thank Jane Griffin, RPh, Lisa Kaspin, PhD, and Ginger Nedblake for their contributions to this manuscript.  ... 
pmid:25593571 pmcid:PMC4272439 fatcat:5zdpaopn2zdzxbnszns7efbsqa

Children's rare disease cohorts: an integrative research and clinical genomics initiative

Shira Rockowitz, Nicholas LeCompte, Mary Carmack, Andrew Quitadamo, Lily Wang, Meredith Park, Devon Knight, Emma Sexton, Lacey Smith, Beth Sheidley, Michael Field, Ingrid A. Holm (+9 others)
2020 npj Genomic Medicine  
Deployment of a genomically-ordered relational database allowed us to provide a modular and robust platform for centralized storage and analysis of research and clinical data, currently totaling 8516 exomes  ...  Research hospitals seeking to implement unified genomics workflows for research and clinical practice face numerous challenges, as they need to address the unique requirements and goals of the distinct  ...  Their vision, input, and feedback on every aspect of the CRDC were invaluable in developing an integrated workflow across our institution to meet the needs of patients, researchers, and clinicians.  ... 
doi:10.1038/s41525-020-0137-0 pmid:32655885 pmcid:PMC7338382 fatcat:wnhd6o6yq5erznyysdegxceriu

An integrated web application for decision support and automation of EHR workflow: a case study of current challenges to standards-based messaging and scalability from the EMBED trial

Edward R Melnick, Wesley C Holland, Osama M Ahmed, Anthony K Ma, Sean S Michael, Howard S Goldberg, Christian Lagier, Gail D'Onofrio, Tomek Stachowiak, Cynthia Brandt, Yauheni Solad
2019 JAMIA Open  
This case report describes the challenges to implementation and scalability of an integrated, web-based CDS intervention for EMergency department-initiated BuprenorphinE for opioid use Disorder which will  ...  Data standards have emerged to facilitate interoperability and rapid integration of such third-party CDS.  ...  All authors revised the manuscript and approved the final version submitted for publication. ERM takes responsibility for all aspects of the work.  ... 
doi:10.1093/jamiaopen/ooz053 pmid:32025639 pmcid:PMC6994013 fatcat:thv5rlo6k5a7fnz5vwanpncom4

Characterizing Data Discovery and End-User Computing Needs in Clinical Translational Science

Parmit K. Chilana, Elishema Fishman, Estella M. Geraghty, Peter Tarczy-Hornoch, Fredric M. Wolf, Nick R. Anderson
2011 Journal of Organizational and End User Computing  
The results also illustrate the benefits of forming early partnerships with scientists to better understand their workflow processes and enduser computing practices in accessing data for research.  ...  In this paper, the authors present the results of a qualitative case-study seeking to characterize data discovery needs and barriers of principal investigators and research support staff in clinical translational  ...  These results further stimulate enthusiasm for tools that would allow and simplify the process of using clinical data for secondary research and better streamline clinical research workflows.  ... 
doi:10.4018/joeuc.2011100102 pmid:24729759 pmcid:PMC3983692 fatcat:juvga6xrczarfeuqr325lsvjvm
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