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An Integrated Framework for High Angular Resolution Diffusion Imaging–Based Investigation of Structural Connectivity
2012
Brain Connectivity
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This article presents an integrated structural connectivity framework designed around such an interpretation. ...
The framework provides three measures to characterize the structural connectivity of a subject: (1) the structural connectivity matrix describing the proportion of connections between pairs of nodes, ( ...
Roberts would like to thank the Oberkircher Family for the Oberkircher Family Chair in Pediatric Radiology. ...
doi:10.1089/brain.2011.0070
pmid:22500705
pmcid:PMC3380149
fatcat:runrlrg2krax5hdjk7vthcciuy
Optimization of macaque brain DMRI connectome by neuron tracing and myelin stain data
2018
Computerized Medical Imaging and Graphics
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Accurate assessment of connectional anatomy of primate brains can be an important avenue to better understand the structural and functional organization of brains. ...
Our results suggest that this integrative framework could advance the mapping accuracy of dMRI based connections and axonal pathways, and demonstrate the prospect of the proposed framework in constructing ...
T Zhang was supported by NSFC 31500798, NSFC 31671005 and the fundamental research funds for the central universities. J Kong was supported by NIH K25CA181503. ...
doi:10.1016/j.compmedimag.2018.06.001
pmid:30170273
pmcid:PMC6176488
fatcat:qqauh2vupzejdahskssdth24rm
D-BRAIN: Anatomically Accurate Simulated Diffusion MRI Brain Data
2016
PLoS ONE
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angular resolution. ...
The proposed framework enables reliable and quantitative evaluation of DW-MR image processing and FT algorithms at the level of large-scale WM structures. ...
that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University for providing part of the data. ...
doi:10.1371/journal.pone.0149778
pmid:26930054
pmcid:PMC4773122
fatcat:5o5k6goiqbg5nfvlrmkav7qsf4
TDF-TRACT: Probabilistic tractography using the tensor distribution function
2011
2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro
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High angular resolution diffusion imaging (HARDI) can potentially resolve more complex diffusion geometries and thus disentangle confounds from fiber incoherence and partial voluming when assessing fiber ...
Fractional anisotropy (FA), a widely used measure of fiber integrity based on diffusion tensor imaging (DTI), is theoretically confounded by several other quantities including the degree of fiber orientation ...
Seven independent gradients are mathematically sufficient to determine the diffusion tensor, but MRI protocols with higher angular and radial resolutions, such as high-angular resolution diffusion imaging ...
doi:10.1109/isbi.2011.5872529
dblp:conf/isbi/GadElkarimZYZALATKL11
fatcat:ok7o5rubr5bfbejov3qk7pmaqy
Brain Structural Connectivity Network Alterations in Insomnia Disorder Reveal a Central Role of the Right Angular Gyrus
2019
NeuroImage: Clinical
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The findings demonstrate that the right angular gyrus is a hub of enhanced structural connectivity in ID. ...
Diffusion-weighted images and T1-weighed images were acquired in 51 people diagnosed with ID (21-69 years of age, 37 female) and 48 matched controls without sleep complaints (22-70 years of age, 31 female ...
This study utilized high angular resolution DWI with 71 diffusion gradient directions, which could lead to higher sensitivity to detect other group differences. ...
doi:10.1016/j.nicl.2019.102019
pmid:31678910
pmcid:PMC6839281
fatcat:wwymdd3et5h4xpsahmhgg37hyu
White matter integrity measured by fractional anisotropy correlates poorly with actual individual fiber anisotropy
2009
2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro
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High-angular resolution diffusion imaging (HARDI) can resolve more complex diffusion geometries than standard DTI, including fibers crossing or mixing. ...
Fractional anisotropy (FA), a very widely used measure of fiber integrity based on diffusion tensor imaging (DTI), is a problematic concept as it is influenced by several quantities including the number ...
Seven independent gradients are mathematically sufficient to determine the diffusion tensor, but MRI protocols with higher angular and radial resolutions, such as the high angular resolution diffusion ...
doi:10.1109/isbi.2009.5193124
dblp:conf/isbi/LeowZZHCBTMZWT09
fatcat:c4z5rc5d6rbi5d5uo3ksve6pva
7T multi-shell hybrid diffusion imaging (HYDI) for mapping brain connectivity in mice
2015
Medical Imaging 2015: Image Processing
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High angular resolution diffusion imaging (HARDI) samples diffusivity at a large number of spherical angles, to better resolve neural fibers that mix or cross. ...
Here, we implemented a framework for advanced mathematical analysis of mouse 5-shell HARDI (b=1000, 3000, 4000, 8000, 12000 s/mm 2 ), also known as hybrid diffusion imaging (HYDI). ...
HYDI offers an unprecedented power to assess the structural connectivity and neural integrity of the mouse brainespecially for studies that aim to validate the diffusion signal with high-resolution histological ...
doi:10.1117/12.2081491
pmid:25859293
pmcid:PMC4386863
dblp:conf/miip/DaianuJVPJBZMT15
fatcat:e37glazfkrhbxljgjwsg4fbsme
HIgh b -value and high Resolution Integrated Diffusion (HIBRID) imaging
2017
NeuroImage
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In this study, we propose a method, termed HIgh b-value and high Resolution Integrated Diffusion (HIBRID) imaging, for acquiring and combining the information from these two complementary types of scan ...
The parameter selection for diffusion MRI experiments is dominated by the "k-q tradeoff" whereby the Signal to Noise Ratio (SNR) of the images is traded for either high spatial resolution (determined by ...
Rockland and Karl Zilles for helpful discussions on connectional neuroanatomy in the brain. We thank Drs. Caroline Magnain and Bruce Fischl for providing OCT images of human brain samples. ...
doi:10.1016/j.neuroimage.2017.02.002
pmid:28188913
pmcid:PMC5501959
fatcat:p6jt2selfrat3ac5tltonclcja
Connectivity and tissue microstructural alterations in right and left temporal lobe epilepsy revealed by diffusion spectrum imaging
2014
NeuroImage: Clinical
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In addition, the high angular and radial resolution of DSI allowed us to evaluate also some of the biophysical compartment models, to better understand the cause of the changes in diffusion anisotropy. ...
Our study provides further structural evidence that RTLE and LTLE are not symmetrical entities and DSI-based imaging could help investigate the microstructural correlate of these imaging abnormalities. ...
The authors would also like to thank Gunnar Krueger from Siemens Schweiz AG for setting up the scanning protocol. ...
doi:10.1016/j.nicl.2014.07.013
pmid:26236626
pmcid:PMC4519999
fatcat:znc34afqtfa2zpztuzq2dqptb4
MR Diffusion Histology and Micro-Tractography Reveal Mesoscale Features of the Human Cerebellum
2013
Cerebellum
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In this study, we report the application of MR diffusion histology and micro-tractography methods to reveal the combined cytoarchitectural organisation and connectivity of the human cerebellum at a resolution ...
State-of-the-art in vivo magnetic resonance imaging (MRI) methods, such as diffusion tractography techniques, can reveal trajectories of the major white matter pathways, but their correspondence with underlying ...
Williams for his continued support and stimulation to push the boundaries of imaging science, as well as Dr. ...
doi:10.1007/s12311-013-0503-x
pmid:23907655
pmcid:PMC3824945
fatcat:fxexf6gfvng6vkbcyqwjl74ib4
Mapping Brain Anatomical Connectivity Using Diffusion Magnetic Resonance Imaging: Structural connectivity of the human brain
2016
IEEE Signal Processing Magazine
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Along with an overview of existing technologies, we also attempt to provide an outlook of future challenges in building a comprehensive connectivity map that integrates genetic and functional information ...
Following years of steady advancement, dMR imaging technique has reached unprecedented spatial and angular resolution, and its computational analysis methods, stimulated by growing research needs, have ...
Future Scope Advances in dMR imaging have provided a platform for investigating brain connectivity in vivo at an unpreceded spatial and angular resolution. ...
doi:10.1109/msp.2015.2510024
pmid:27212872
pmcid:PMC4869891
fatcat:nkfwwsp6cnatlmeaah2stye2n4
An investigation of the white matter microstructure in motion detection using diffusion MRI
2014
Brain Research
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Correlation was calculated between the motion detection threshold and white matter microstructure as measured by high angular resolution diffusion MRI. ...
One of the most widely investigated functions of the brain is vision. ...
Acknowledgement The study was supported by the "Neuroscience Research Group of the Hungarian Academy of Sciences and University of Szeged", project FNUSA-ICRC (no. ...
doi:10.1016/j.brainres.2014.05.006
pmid:24833063
fatcat:nwqyc5glsvaffpvofz2mtqpyka
Fusion of white and gray matter geometry: A framework for investigating brain development
2014
Medical Image Analysis
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Current neuroimaging investigation of the white matter typically focuses on measurements derived from diffusion tensor imaging, such as fractional anisotropy (FA). ...
Its formulation is based on the differential geometry of curve sets and is easily incorporated into a continuous scale-space framework. ...
Siddiqi, "Labeling of ambiguous sub-voxel fibre bundle configurations in high angular resolution diffusion MRI", NeuroImage, 41(
P. Savadjiev, J. S. W. Campbell, G. B. Pike and K. ...
doi:10.1016/j.media.2014.06.013
pmid:25066750
pmcid:PMC4162846
fatcat:ul4n7c47knazbdoykjcbggjo54
A Novel Measure of Fractional Anisotropy Based on the Tensor Distribution Function
[chapter]
2009
Lecture Notes in Computer Science
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Fractional anisotropy (FA), a very widely used measure of fiber integrity based on diffusion tensor imaging (DTI), is a problematic concept as it is influenced by several quantities including the number ...
With High-angular resolution diffusion imaging (HARDI) and the tensor distribution function (TDF), one can reconstruct multiple underlying fibers per voxel and their individual anisotropy measures by representing ...
Seven independent gradients are mathematically sufficient to determine the diffusion tensor, but MRI protocols with higher angular and radial resolutions, such as the high angular resolution diffusion ...
doi:10.1007/978-3-642-04268-3_104
fatcat:5r3gpidcjnetbph4k65jnkgnoa
Localization and imaging of white matter fiber crossings in whole mouse brains using diffusion MRI and serial blockface OCT
2021
Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics
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To obtain an accurate representation of a brain structural connectivity, diffusion MRI and fiber tracking depend on a good understanding of white matter fiber structures. ...
Our method uses the Allen Mouse Brain connectivity atlas and tractogram analysis using diffusion MRI techniques to identify candidate regions of interests containing fiber crossings based on two predetermined ...
We also wish to express our gratitude to all the open science efforts, such as the mouse brain images and the connectivity data shared by the Allen Mouse Brain Institute and by the Neuroinformatics-NL ...
doi:10.1117/12.2577648
fatcat:zx7wrpafj5ar3psgyy3r362q6m
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