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A METHODOLOGY FOR DESIGNING HIGH CONFIDENCE PATTERN VIA EVENT B
2017
International Journal of Intelligent Computing and Information Sciences
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In this paper we discuss these two types on Insulin Infusion Pump (IIP) and sample of UML class diagrams. The proposed approach to formalize IIP is based on using event B. ...
Finally, we could verify that the code generated from the proposed approach is correct and formal to use as a pattern. ...
Ref3: This refinement introduce the time issues and the corresponding solutions for them prob2 by applying several timing patterns to the infusion process in the IIP. ...
doi:10.21608/ijicis.2017.9149
fatcat:gcustkk4afhbvlrulfdt7egm7i
Stepwise Formal Modelling and Reasoning of Insulin Infusion Pump Requirements
[chapter]
2015
Lecture Notes in Computer Science
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An insulin infusion pump (IIP) is a critical software-intensive medical device that infuses insulin satisfying patient needs under safety and timing constraints that are appropriate for the treatment of ...
This paper presents an incremental proof-based development of an IIP. We use the Event-B modelling language to formalize the given system requirements. ...
Moreover, we have plans to a closed-loop system using our gluhomeostasis model [3] to verify the correctness of system behaviour, to analyze system operations, and to provide the required safety assurances ...
doi:10.1007/978-3-319-21070-4_39
fatcat:yo2gbbw4jrdebdlrhagrcgkf4a
Insulin Pump Risks and Benefits: A Clinical Appraisal of Pump Safety Standards, Adverse Event Reporting, and Research Needs
2015
Diabetes Care
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However, even with modern insulin pumps, errors of insulin infusion can occur due to pump failure, insulin infusion set (IIS) blockage, infusion site problems, insulin stability issues, user error, or ...
Insulin pump therapy, also known as continuous subcutaneous insulin infusion (CSII), is an important and evolving form of insulin delivery, which is mainly used for people with type 1 diabetes. ...
We would like to thank Viktor Jörgens (Executive Director, EASD), Monika Grüsser (Vice Director, EASD), and Robert Ratner (Chief Scientific and Medical Officer, ADA) for ...
doi:10.2337/dc15-0168
pmid:25776138
fatcat:vzjm6xfrenaoljw23fxovl3rt4
Real-Time Hypoglycemia Prediction Suite Using Continuous Glucose Monitoring: A safety net for the artificial pancreas
2010
Diabetes Care
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CONCLUSIONS -The HPA will enable automated insulin-pump suspension in response to a pending event that has been detected prior to severe immediate complications. ...
During these admissions, hypoglycemia was induced by gradual increases in the basal insulin infusion rate up to 180% from the subject's own baseline infusion rate. ...
On one hand, longer prediction time may provide greater ability to prevent hypoglycemia events; on the other hand, it may be impractical to suspend a pump too far from an event that may not happen due ...
doi:10.2337/dc09-1487
pmid:20508231
pmcid:PMC2875433
fatcat:3nf3iivp6zgcjdzerui4cwl2v4
Insulin pump risks and benefits: a clinical appraisal of pump safety standards, adverse event reporting and research needs. A Joint Statement of the European Association for the Study of Diabetes and the American Diabetes Association Diabetes Technology Working Group
2015
Diabetologia
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Insulin pump therapy, also known as continuous subcutaneous insulin infusion (CSII), is an important and evolving form of insulin delivery, which is mainly used for people with type 1 diabetes. ...
This statement concludes with a series of recommended specific actions for 'meknovigilance' (i.e. a standardised safety approach to technology) which could be implemented to address the shortcomings we ...
All authors approved the final version to be published. ...
doi:10.1007/s00125-015-3513-z
pmid:25784563
fatcat:efyzwqdaavdkvoav72jqkyfrie
Continuous Glucose Monitoring Enables the Detection of Losses in Infusion Set Actuation (LISAs)
2017
Sensors
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Therefore, an algorithm for the detection of LISAs based on CGM and CSII signals was developed to improve patient safety. ...
In addition to artificial pancreas algorithms that use CGM to automate continuous subcutaneous insulin infusion (CSII), CGM can also inform fault detection algorithms that alert patients to problems in ...
Time points with retrospective alarms are shaded in red; (B) the basal and bolus insulin administration is passed to a second-order filter to determine the plasma insulin estimate (PIE); (C) the IFM calculated ...
doi:10.3390/s17010161
pmid:28098839
pmcid:PMC5298734
fatcat:h74sjn3a6veshoaj5prh5km4em
Early Detection of Infusion Set Failure During Insulin Pump Therapy in Type 1 Diabetes
2016
Journal of Diabetes Science and Technology
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Declaration of Conflicting Interests The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article:
Funding The author ...
(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: JDRF Grant 17-2013-471 and National Institutes of Health Grant DP3DK094331. ...
To the best of the authors knowledge this is the first time that a method with these features has been applied to actual outpatient data. ...
doi:10.1177/1932296816663962
pmid:27621142
pmcid:PMC5094340
fatcat:hgzmzj2brjfbzoaqpsjcw6hs2i
Guidelines for Application of Continuous Subcutaneous Insulin Infusion (Insulin Pump) Therapy in the Perioperative Period
2012
Journal of Diabetes Science and Technology
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Although the work group identified safety issues specific to surgical scenarios, it believed that with the use of standardized guidelines and a checklist, continuation of insulin pump therapy during the ...
Abbreviations: (CSII) continuous subcutaneous insulin infusion, (PACU) postanesthesia care unit Abstract Case reports indicate that diabetes patients receiving outpatient insulin pump therapy have been ...
Similar to the approach taken to implementing an inpatient insulin pump policy, a successful approach to perioperative insulin pump use will depend on a collaborative relationship among the patient, the ...
doi:10.1177/193229681200600123
pmid:22401338
pmcid:PMC3320837
fatcat:xrofdt5gefcfzafqlfeaofrk2e
A Hazard Analysis of Class I Recalls of Infusion Pump (Preprint)
2018
JMIR Human Factors
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This study aimed to establish a hazard classification framework of medical devices and to apply it over practical adverse event data on infusion pumps. ...
According to the analytical results, an important source of product technical risk was that the infusion pumps did not infuse accurate dosage (ie, over- or underdelivery of fluid). ...
Multimedia Appendix 1: [The hazard classification of 2001 ～ 2017 class Ⅰ infusion pump recalls extracted from FDA website.] ...
doi:10.2196/10366
pmid:31066695
pmcid:PMC6524450
fatcat:uewivk7bofatvmvi4a223gbope
Insulin Infusion Set Use: European Perspectives and Recommendations
2016
Diabetes Technology & Therapeutics
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Insulin pump users worldwide depend on insulin infusion sets (IISs) for predictable delivery of insulin to the subcutaneous tissue. ...
Yet emerging data indicates that IISs are associated with many pump-related adverse events and may contribute to potentially life-threatening problem of unexplained hyperglycemia. ...
C.C. has patent applications related to glucose sensors and the artificial pancreas; he has received non-financial support from Roche and Dexcom, and received research support, managed by University of ...
doi:10.1089/dia.2016.07281.sf
pmid:27526329
pmcid:PMC5040072
fatcat:rpwa25xgr5ctbfi55bfvbnhmme
Patient Infusion Pattern based Access Control Schemes for Wireless Insulin Pump System
2015
IEEE Transactions on Parallel and Distributed Systems
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This scheme employs supervised learning approaches to learn normal patient infusion patterns in terms of the dosage amount, rate, and time of infusion, which are automatically recorded in insulin pump ...
The generated regression models are used to dynamically configure a safe infusion range for abnormal infusion identification. ...
ACKNOWLEDGMENTS This work was supported in part by the US NSF under grants CNS-0963578, CNS-1022552, CNS-1065444, IIS-1231680, CNS-1239108, as well as CNS-1035715. ...
doi:10.1109/tpds.2014.2370045
fatcat:l5tpyzxuovbdpf6zwmp32klrp4
Update on a Quality Initiative to Standardize Perioperative Care for Continuous Subcutaneous Insulin Infusion Therapy
2015
Journal of Diabetes Science and Technology
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Preoperative contact is an opportune time to educate the patient on the inpatient insulin pump policy outside of the surgical day which is often accompanied by increased stress, unfamiliar transitions, ...
Patients are asked about their diabetes type and duration, their current glucose control, length of time that they have been using an insulin pump, the pump brand, current pump rates, settings, and brand ...
doi:10.1177/1932296815592027
pmid:26092687
pmcid:PMC4667318
fatcat:p5ecob3wqbhcvhzqqizzau6hyi
Confusion Regarding Duration of Insulin Action
2014
Journal of Diabetes Science and Technology
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; IAT, insulin action time; IOB, insulin on board; PD, pharmacodynamic; PK, pharmacokinetic; SC, subcutaneous. ...
Abbreviations BC, bolus calculator; BOB, bolus insulin on board; carb, carbohydrate; CGM, continuous glucose monitor; DIA, duration of insulin action; GIR, glucose infusion rate; HGP, hepatic glucose production ...
from an insulin pump) before the test insulin is applied. ...
doi:10.1177/1932296813514319
pmid:24876553
pmcid:PMC4454113
fatcat:7eiux7tnjzgcvfjrsw235jpfrq
Preclinically assessed optimal control of postprandial glucose excursions for type 1 patients with diabetes
2011
2011 IEEE International Conference on Automation Science and Engineering
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Model parameters are identified for every couple (Patient, Meal) of interest and optimal control is applied to generate individualized meal specific insulin profiles. ...
The method does not require the use of a continuous BG meter, the profiles being infused in an open-loop manner. Results from a preliminary clinical study are presented. ...
Important safety issues related to the automatically changing insulin infusion generated by an AP are another drawback. ...
doi:10.1109/case.2011.6042510
dblp:conf/case/PrudhommeBFG11
fatcat:egixnrjgljhsxhi372sgie2aay
SMARTDIAB: A Communication and Information Technology Approach for the Intelligent Monitoring, Management and Follow-up of Type 1 Diabetes Patients
2010
IEEE Transactions on Information Technology in Biomedicine
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The PU consists of an insulin pump for subcutaneous insulin infusion to the patient and a continuous glucose measurement system. ...
The IIAS is used to close the loop between the insulin pump and the continuous glucose monitoring system, by providing the pump with the appropriate insulin infusion rate in order to keep the patient's ...
Furthermore, they would like to thank Medtronic (Athens, Greece) for the provision of the continuous glucose systems (CGMS and Guardian RT) and the insulin pumps. ...
doi:10.1109/titb.2009.2039711
pmid:20123578
fatcat:lo5jc5qc6jdq5pt2ilbbwa6qdi
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