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Techniques in Iterative Proton CT Image Reconstruction

Scott Penfold, Yair Censor
2015 Sensing and Imaging  
This is a review paper on some of the physics, modeling, and iterative algorithms in proton computed tomography (pCT) image reconstruction.  ...  These algorithmic schemes allow flexibility of choosing blocks, strings, and other parameters. They also cater for parallel implementations which are apt to further save clock time in computations.  ...  The authors also thank Dan Gordon for reading and constructively commenting on an earlier version of the paper. We thank three anonymous referees for their reviews which helped us improve the paper.  ... 
doi:10.1007/s11220-015-0122-3 fatcat:2unqez4lzvhy7dowhzt5rng4rq

An Improved Method of Total Variation Superiorization Applied to Reconstruction in Proton Computed Tomography [article]

Blake Schultze, Yair Censor, Paniz Karbasi, Keith E. Schubert, and Reinhard W. Schulte
2019 arXiv   pre-print
Previous work showed that total variation superiorization (TVS) improves reconstructed image quality in proton computed tomography (pCT).  ...  This work demonstrates that the modifications related to the evolution of the original TVS algorithm provide benefits in terms of both pCT image quality and computational efficiency for appropriately chosen  ...  The support of UT Southwestern and State of Texas through a Seed Grants in Particle Therapy award is gratefully acknowledged.  ... 
arXiv:1803.01112v3 fatcat:sb4mng3uhfdxzjxvdjcsqttma4

Network Health and e-Science in Public Clouds

Ryan Chard, Kris Bubendorfer, Bryan Ng
2014 2014 IEEE 10th International Conference on e-Science  
Finally, we evaluate our work through a real-world medical image reconstruction application.  ...  Commercial cloud providers are increasingly offering high performance and GPU-enabled resources capable of facilitating e-Science applications.  ...  The pCT codes were used to reconstruct a 131 million proton history image over eight instances, utilizing two processes per instance to match each available GPU.  ... 
doi:10.1109/escience.2014.36 dblp:conf/eScience/ChardBN14 fatcat:byyw3r6s7vgz5b7w4jyydholhu

Particle-Tracking Proton Computed Tomography Data Acquisition, Preprocessing, and Preconditioning

Blake Schultze, Paniz Karbasi, Christina Sarosiek, George Coutrakon, Caesar E. Ordonez, Nicholas T. Karonis, Kirk Duffin, Vladimir Bashkirov, Robert P. Johnson, Keith E. Schubert, Reinhard W. Schulte
2021 IEEE Access  
and the implementation of these algorithms on a hybrid CPU/GPU computer cluster.  ...  In a series of two contributions, we focus on presenting the software algorithms that convert pCT detector data to the final reconstructed pCT images for application in proton treatment planning.  ...  The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of NBIB, NIH, NSF, the Department of Defense, or the Department of Energy.  ... 
doi:10.1109/access.2021.3057760 pmid:33996341 pmcid:PMC8117661 fatcat:e7lplpjzang4zbu6u4darydycu

Network health and e-Science in commercial clouds

Ryan Chard, Kris Bubendorfer, Bryan Ng
2016 Future generations computer systems  
. • An overall health system is constructed using tomographic probes to establish and compare an instance's network performance. • We deploy the health system over a testbed of 100 AWS instances and explore  ...  We then explore the suitability of a range of tomographic techniques to act as health indicators using two testbeds-the second of which spanned one hundred AWS instances.  ...  The pCT codes were used to reconstruct a 131 million proton history image over eight instances, utilizing two processes per instance to match each available GPU.  ... 
doi:10.1016/j.future.2015.06.001 fatcat:4terprl7ubhvvpw5t5a37epnxe

Development of proton computed tomography detectors for applications in hadron therapy

Vladimir A. Bashkirov, Robert P. Johnson, Hartmut F.-W. Sadrozinski, Reinhard W. Schulte
2016 Nuclear Instruments and Methods in Physics Research Section A : Accelerators, Spectrometers, Detectors and Associated Equipment  
Proton computed tomography (pCT) is an emerging imaging modality capable of improving the accuracy of range prediction.  ...  An overview of a decade-long evolution of the conceptual design of pCT scanners and their calibration is given.  ...  Acknowledgments The authors would like to thank a large number of individuals (physicists, engineers, accelerator staff, postdocs and students) who have contributed to the success of the pCT collaboration  ... 
doi:10.1016/j.nima.2015.07.066 pmid:26957679 pmcid:PMC4779442 fatcat:zx6ue626mjet5jb5lc5of2cc7a

Water-equivalent path length calibration of a prototype proton CT scanner

R. F. Hurley, R. W. Schulte, V. A. Bashkirov, A. J. Wroe, A. Ghebremedhin, H. F.-W. Sadrozinski, V. Rykalin, G. Coutrakon, P. Koss, B. Patyal
2012 Medical Physics (Lancaster)  
Purpose: The authors present a calibration method for a prototype proton computed tomography (pCT) scanner.  ...  A cylindrical water phantom was scanned with 200 MeV protons and its RSP distribution was reconstructed using the 200 MeV calibration.  ...  W81XWH0-08-1-0205, and the Loma Linda University Medical Center, Department of Radiation Medicine.  ... 
doi:10.1118/1.3700173 pmid:22559614 pmcid:PMC3338592 fatcat:7d3ggs7sffgtvcoca23qjtzuxi

Imaging with protons at MedAustron [article]

F. Ulrich-Pur, T. Bergauer, A. Burker, S. Hatamikia, A. Hirtl, C. Irmler, S. Kaser, P. Paulitsch, F. Pitters, V. Teufelhart
2020 arXiv   pre-print
A more precise method to acquire the SP is to directly use high energy protons (or other ions such as carbon) and perform proton computed tomography (pCT).  ...  Currently, treatment planning for proton therapy is based on X-ray computed tomography, which entails certain sources of inaccuracy in alculation of the stopping power (SP).  ...  Acknowledgements The authors would like to thank A. Bauer, W. Brandner, S. Schultschik, B. Seiler, R. Stark, H. Steininger, R. Thalmeier and H.  ... 
arXiv:2003.00115v3 fatcat:etwspxp3mfhmfmmlie3zwa2nia

Derivatives in Proton CT [article]

Max Aehle, Johan Alme, Gergely Gábor Barnaföldi, Johannes Blühdorn, Tea Bodova, Vyacheslav Borshchov, Anthony van den Brink, Mamdouh Chaar, Viljar Eikeland, Gregory Feofilov, Christoph Garth, Nicolas R. Gauger (+40 others)
2022 arXiv   pre-print
Proton computed tomography (pCT) is a medical imaging technology with the potential to increase the spatial accuracy of the dose delivered in proton-beam radiotherapy.  ...  The Bergen pCT collaboration is developing and constructing a digital tracking calorimeter (DTC) to measure the position, direction and energy of protons after they passed through a patient, and a software  ...  NKFIH OTKA K135515 grant and the Wigner Scientific Computing Laboratory (WSCLAB).  ... 
arXiv:2202.05551v1 fatcat:hxwi6cdbpvallokv6izs6eq4fm

Review of medical radiography and tomography with proton beams

Robert P Johnson
2017 Reports on progress in physics (Print)  
associated reconstruction codes for proton computed tomography (pCT) as well as more simple proton radiography, with the ultimate intention to use such systems in clinical treatment planning and verification  ...  Already a half century ago suggestions were made to use protons themselves to develop images of tumors and surrounding tissue, to be used for treatment planning.  ...  To get an idea of the computational problem, consider that 6 hours were required in Ref. [68] to reconstruct an image from 130 million proton histories using a single CPU coupled to one GPU.  ... 
doi:10.1088/1361-6633/aa8b1d pmid:28884707 fatcat:vobe4ynkvjh2riovte5ng75gxi

Proceedings to the 4th Annual Conference of the Particle Therapy Cooperative Group North America (PTCOG-NA)

2018 International Journal of Particle Therapy  
METHODS: IMPT plans of 13 patients treated prior to the implementation of a BP BD constraint (cohort 1) were compared with IMPT plans of 38 patients treated after the implementation of a BP BD constraint  ...  All patients were treated with double scattered proton therapy to the left breast (n¼3) or chestwall with reconstruction (n¼2) and regional lymphatics including internal mammary nodes with FB to a total  ...  MATERIALS AND METHODS: A patient positioning and immobilization unit as a part of proton therapy complex ''Prometheus,'' civco thermoplastic masks, an X-Ray cone-beam computer tomograph, daily verification  ... 
doi:10.14338/ijpt.18-ptcog-2.1 pmid:31773015 pmcid:PMC6871569 fatcat:f5sv5qqdqzgrjjlc4sc4rq2u6i

Imaging in Nuclear Medicine

Matthew Palmer
2016 Medical Physics (Lancaster)  
., for assistance in the final preparation of the manuscript.  ...  Acknowledgments The authors would like to thank Gernot Ebel for useful comments and suggestions during the preparation of this contribution.  ...  In-line Proton Computed Tomography in Hadron Therapy Investigation on proton computed tomography (PCT) started 30 years ago and appeared to be a good alternative to X-ray CT scan in terms of more accurate  ... 
doi:10.1118/1.4947510 pmid:27277065 fatcat:6l6n46bpinfv3eqawoejvjkp3i

Performance Improvements and Analysis of Image Reconstruction Techniques in Proton Computed Tomography

Benjamin Kirchmayer, Albert Hirtl, Thomas Bergauer
Since the computations in pCT image reconstruction are well suited to be executed in parallel, this approach has also gained momentum for application to pCT.  ...  The performance of the computations is increased by conducting parts of the calculations in parallel on a GPGPU (general [...]  ...  Due to TIGRE's modular structure, implementing new CUDAa ccelerated modulesi spossible without changingt he source code of thet oolbox.T herefore, an extensiont ot he TIGREt oolbox for pCT can be implemented  ... 
doi:10.34726/hss.2021.94905 fatcat:5dgbhnuxavgztmkbu5kinzjrly

Proceedings to the 2020 Online Conference of the Particle Therapy Cooperative Group (PTCOG2020Online)

2021 International Journal of Particle Therapy  
As a next step, we will implement an automatic pipeline in our facility which exploits the high computational efficiency of FRED.  ...  A web-based analysis program was implemented to perform the data analysis and show the trend of the results.  ...  We used a Monte Carlo simulation on the top of GEANT4, well benchmarked for both proton a carbon ion beams.The beam line is a realistic one.  ... 
doi:10.14338/ijpt.20-ptcog-7.4 pmid:33829075 pmcid:PMC8019577 fatcat:v2kbh3jnazck3jbyjk6fu6ckfi

Power pulsing of the CALICE tile hadron calorimeter

Mathias Reinecke
2016 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)  
DUNE consists of an intense neutrino beam fired a distance of 1300 km from Fermilab (near Chicago) to the 40,000 ton Liquid Argon DUNE detector, located deep underground in the Homestake mine.  ...  Nevertheless, as a result of a series of innovative large experiments in the last 20 years, we have learnt a great deal about neutrinos.  ...  M04D-15: Monte Carlo Simulation of DNA Damage Clustering Induced by a 24 MeV Proton Beam The authors want to thank Professor Lars R.  ... 
doi:10.1109/nssmic.2016.8069748 fatcat:zjgd7dmfdbhntb4kfwdtrlejhi
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