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White matter involvement after TBI: Clues to axon and myelin repair capacity
2016
Experimental Neurology
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forces to the head cause traumatic brain injury (TBI) with damage in white matter tracts comprised of long axons traversing the brain. ...
White matter injury after TBI involves both traumatic axonal injury (TAI) and myelin pathology that evolves throughout the post-injury time course. ...
White matter injury is a major component of TBI White matter atrophy dramatically demonstrates significant white matter involvement in moderate-severe forms of TBI in patients who survive to a chronic ...
doi:10.1016/j.expneurol.2015.02.011
pmid:25697845
fatcat:3khlgkffmrbszj6ggfojj3cqze
Transfer of orbital angular momentum from a super-continuum, white-light beam
2008
Optics Express
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2008) Transfer of orbital angular momentum from a supercontinuum, white-light beam. Optics Express, 16 (13). pp. 9495-9500. ...
We illustrate the achromatic, helical phase structure of a white-light beam by observing the transfer of its orbital angular momentum to particles held in optical tweezers. ...
To axially confine the 1μm diameter polystyrene particles we prepared the sample cell as a thin (< 100μm) water layer between a microscope slide and cover slip. ...
doi:10.1364/oe.16.009495
pmid:18575514
fatcat:3mv4qfxlb5gy3gq72hfvxerv4y
Relationship between abdominal fat and bone mineral density in white and African American adults
2012
Bone
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The sample included 330 white women, 328 African American women, 307 white men, and 116 African American men 18-74 years of age. ...
In conclusion, BMD was inversely related to abdominal VAT and SAT in white and African American adults after adjustment for LBM. ...
The average age of the sample was 42.1 years (range, 18-74 years) and the average BMI was 31 kg/m 2 (range, 17-45 kg/m 2 ). ...
doi:10.1016/j.bone.2011.04.012
pmid:21549867
pmcid:PMC3936414
fatcat:5ytzhmmtvjccdbplpaoq5atb4q
Engineered bromodomains to explore the acetylproteome
2015
Proteomics
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Acknowledgments The author would like to thank the White Lab for valuable conversations and Duaa Muhammad for supplying yeast DNA. ...
Table 1 1 K D Measurements of Engineered Bromodomain-Containing Proteins Protein
K D (M)
BDF1-A 1.11×10 −6
BDF1-B 2.14×10 −7
BDF1
1.67×10 −8
GCN5
2.25×10 −5
GLB
1.08×10 −7 ...
doi:10.1002/pmic.201400401
pmid:25641834
pmcid:PMC4535431
fatcat:3n6jzdyuazgqjedz5iczhltpgy
Associations of postpartum sleep, stress, and depressive symptoms with LPS-stimulated cytokine production among African American and White women
2018
Journal of Neuroimmunology
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., depressive symptoms), serum cytokine levels, and LPS-stimulated proinflammatory cytokine production among 69 women (32 African American, 37 White) assessed at 7-10 weeks postpartum. ...
In African American women, but not Whites, poorer sleep quality, greater parenting stress, and greater depressive symptoms were associated with greater LPSstimulated IL-6 and IL-8 production (ps ≤ 0.05 ...
Maternal body mass index (BMI; kg/m 2 ) was calculated using weight and height measured by nursing staff at the study visit. ...
doi:10.1016/j.jneuroim.2017.12.020
pmid:29406850
pmcid:PMC5806133
fatcat:grwzkm6vvnce3pojxazdkvnuwq
Complementary and Alternative Medicine for Mental Disorders Among African Americans, Black Caribbeans, and Whites
2009
Psychiatric Services
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K Ka ai i M M. . B Bu ul ll la ar rd d, , P Ph h. .D D. . R Ro ob be er rt t J J. . T Ta ay yl lo or r, , P Ph h. .D D. . L Li in nd da a M M. . C Ch ha at tt te er rs s, , P Ph h. .D D. . ...
B Ba as se er r, , M M. .S S. . B Br ri ia an n E E. . P Pe er rr ro on n, , P Ph h. .D D. . J Ja am me es s S S. . J Ja ac ck ks so on n, , P Ph h. ...
Jackson JS, Torres M, Caldwell CH, et al: The National Survey of American Life: a study of racial, ethnic, and cultural influences on mental disorders and mental health. ...
doi:10.1176/ps.2009.60.10.1342
pmid:19797374
pmcid:PMC3058881
fatcat:tohudrtmm5c5zk74futfaxh2b4
White Matter Injury in Term Newborns With Neonatal Encephalopathy
2009
Pediatric Research
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White matter injury (WMI) is the characteristic pattern of brain injury detected on magnetic resonance imaging in the premature newborn. ...
Figure 1 . 1 Severity of acute white matter injury. White matter injury (WMI) has a wide range of severity in the term newborn. ...
Figure 2 . 2 Acute focal white matter injury and acute stroke. T 1 -weighted sequence of patient 5 (A) shows a focal area of white matter injury (WMI) (arrow) in the right frontal lobe. ...
doi:10.1203/pdr.0b013e31818912d2
pmid:18787422
fatcat:dvzpmyt2njeetiaa5ywhey7y5e
Myelin and oligodendrocyte lineage cells in white matter pathology and plasticity after traumatic brain injury
2016
Neuropharmacology
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TAI occurs in a pattern of damaged axons dispersed among intact axons in white matter tracts. ...
White matter pathology after TBI depends on the extent and distribution of axon damage, microhemorrhages and/or neuroinflammation. ...
With TAI, damaged axons are dispersed among intact axons within white matter tracts. ...
doi:10.1016/j.neuropharm.2015.04.029
pmid:25963414
fatcat:megkoouolfhjzhwfdkdnl62v5u
Time Constraints Limit Group Sizes and Distribution in Red and Black-and-White Colobus
2007
International journal of primatology
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Psychosocial costs of racism to whites: Exploring patterns through cluster analysis
2006
Journal of Counseling Psychology
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Participants (230 White college students) completed the Psychosocial Costs of Racism to Whites (PCRW) Scale. ...
S D
M
S D
M
S D
M
S D
M
S D
CoBRAS
Racial Privilege
26.90
6.55
26.02
5.38
21.81
5.90
22.31
6.36
28.28
5.72
9.38*
.15
C, D Ͻ A, B, E
Institutional Racism
26.98
5.76
24.54
5.02 ...
Method
Participants Participants were 230 self-identified White undergraduate students (36% men, 64% women) aged 18 -44 years (M ϭ 29.42, SD ϭ 2.15) attending a large Midwestern university. ...
doi:10.1037/0022-0167.53.4.434
fatcat:gvfzpasi35ao5jkl6uxdy2g4n4
Cerebellar Purkinje cell microcircuits are essential for tremor
[article]
2019
bioRxiv
pre-print
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White J.J., Arancillo M., Stay T.L., et al. (2014) Cerebellar Zonal Patterning Relies on Purkinje Cell Neurotransmission. J Neurosci 34(24), 8231-8245. ...
Arancillo M., White J.J., Lin T., et al. (2015) In vivo analysis of Purkinje cell firing properties during postnatal mouse development. J Neurophysiol 113(2), 578-591. . ...
doi:10.1101/770321
fatcat:qaiwi2cmdnaprb73gb5w64pmui
Influence of age on peripheral refraction
2005
Vision Research
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are usually asymmetrical about fixation, and in the case of the horizontal visual field, the astigmatic refractive errors are usually higher in the nasal side than the temporal side (Dunne, Misson, White ...
Table 1 1 Subject numbers, age and M (mean spherical refraction) for the young and older refractive error groups Young
Older
n
Age (years)
M (D)
n
Age (years)
M (D)
Low hyperopes
-
-
-
17
59 ...
doi:10.1016/j.visres.2004.09.028
pmid:15639498
fatcat:3s7p7po2obdpvmyaviso7vkq3a
Quantifying oncogenic phosphotyrosine signaling networks through systems biology
2010
Current Opinion in Genetics and Development
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Acknowledgments We would like to thank members of the Forest White lab for helpful discussions regarding this review. This work was supported by National Cancer Institute Grant CA118705. ...
doi:10.1016/j.gde.2009.12.005
pmid:20074929
pmcid:PMC3694410
fatcat:4qvncjthhjf5hnky3ydtrkoqdy
Evaluating concentration estimation errors in ELISA microarray experiments
2005
BMC Bioinformatics
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Enzyme-linked immunosorbent assay (ELISA) is a standard immunoassay to estimate a protein's concentration in a sample. Deploying ELISA in a microarray format permits simultaneous estimation of the concentrations of numerous proteins in a small sample. These estimates, however, are uncertain due to processing error and biological variability. Evaluating estimation error is critical to interpreting biological significance and improving the ELISA microarray process. Estimation error evaluation
doi:10.1186/1471-2105-6-17
pmid:15673468
pmcid:PMC549203
fatcat:wpaa2utbwrejzfet6pxz6564c4
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... be automated to realize a reliable high-throughput ELISA microarray system. In this paper, we present a statistical method based on propagation of error to evaluate concentration estimation errors in the ELISA microarray process. Although propagation of error is central to this method and the focus of this paper, it is most effective only when comparable data are available. Therefore, we briefly discuss the roles of experimental design, data screening, normalization, and statistical diagnostics when evaluating ELISA microarray concentration estimation errors. We use an ELISA microarray investigation of breast cancer biomarkers to illustrate the evaluation of concentration estimation errors. The illustration begins with a description of the design and resulting data, followed by a brief discussion of data screening and normalization. In our illustration, we fit a standard curve to the screened and normalized data, review the modeling diagnostics, and apply propagation of error. We summarize the results with a simple, three-panel diagnostic visualization featuring a scatterplot of the standard data with logistic standard curve and 95% confidence intervals, an annotated histogram of sample measurements, and a plot of the 95% concentration coefficient of variation, or relative error, as a function of concentration. This statistical method should be of value in the rapid evaluation and quality control of high-throughput ELISA microarray analyses. Applying propagation of error to a variety of ELISA microarray concentration estimation models is straightforward. Displaying the results in the three-panel layout succinctly summarizes both the standard and sample data while providing an informative critique of applicability of the fitted model, the uncertainty in concentration estimates, and the quality of both the experiment and the ELISA microarray process.
Pathophysiology of Dyt1 dystonia is mediated by spinal cord dysfunction
[article]
2022
bioRxiv
pre-print
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Scale: 1s (M), 0.1s (N-O).
513
Fig. 3 514Figure 3 . 33 Fig. 3
Fig. 4 .Fig. 4 44 Fig. 4.
Fig. 5 .Fig. 5 55 Fig. 5. ...
Thus, we recorded L4 and L5 dorsal root volleys in response to root stimulation (Fig. 5K ), and found slower afferent conduction velocities in spinal Tor1a d-cko mice compared to controls (Fig. 5L-M ...
doi:10.1101/2022.05.05.490750
fatcat:nmyotovq3zcadd6urr6jgnxadm
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