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Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical Trial

Maria I Danila, Ryan C Outman, Elizabeth J Rahn, Amy S Mudano, David T Redden, Peng Li, Jeroan J Allison, Fred A Anderson, Allison Wyman, Susan L Greenspan, Andrea Z LaCroix, Jeri W Nieves (+8 others)
2018 Journal of Bone and Mineral Research  
Osteoporosis treatment rates are declining, even among those with past fractures. Novel, low-cost approaches are needed to improve osteoporosis care. We conducted a parallel group, controlled, randomized clinical trial evaluating a behavioral intervention for improving osteoporosis medication use. A total of 2,684 women with self-reported fracture history after age 45 not using osteoporosis therapy from U.S. Global Longitudinal study of Osteoporosis in Women (GLOW) sites were randomized 1:1 to
more » ... eceive a multi-modal, tailored, direct-to-patient, video intervention vs. usual care. The primary study outcome was self-report of osteoporosis medication use at 6months. Other outcomes included calcium and vitamin D supplementation, bone mineral density Methods Study Design and Participants The APROPOS study was a parallel, controlled, randomized clinical trial, in which participants received either usual care alone (control group), or in combination with a multimodal, patient-tailored, behavioral intervention (intervention group). (16) APROPOS was nested within the GLOW cohort, (40) an international, prospective, observational study of women 55+ years of age. The participants in APROPOS were enrolled from 7 U.S. GLOW sites (Birmingham, AL; Los Angeles, CA; Worcester, MA; New York, NY; Cincinnati, OH; Pittsburgh, PA; Seattle, WA). Human subject protocols and consent procedures were reviewed and approved by each site's Institutional Review Board. GLOW participants were preliminarily eligible for APROPOS if on one of the five GLOW surveys they self-reported a fracture after age 45. In September 2013, we mailed baseline questionnaires to 4,928 preliminarily eligible GLOW participants; 3,226 (64%) completed baseline surveys, of which 2,684 women, who did not report currently using osteoporosis medication (the second eligibility criteria) besides estrogen, formed the APROPOS study population, and were randomized. Danila et al.
doi:10.1002/jbmr.3395 pmid:29377378 pmcid:PMC6016546 fatcat:fttvj552ijf7fhvvu2quaui43i

Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology

Crystal S. Denlinger, Tara Sanft, K. Scott Baker, Gregory Broderick, Wendy Demark-Wahnefried, Debra L. Friedman, Mindy Goldman, Melissa Hudson, Nazanin Khakpour, Allison King, Divya Koura, Robin M. Lally (+22 others)
2018 The Journal of the National Comprehensive Cancer Network  
LYMPHEDEMA Survivorship, Version 2.2018 SURVIVOR AT RISK SURVEILLANCE SYMPTOM WORKUP IF LYMPHEDEMA TREATMENT FOR LYMPHEDEMA ASSESSMENT IS SUSPECTED • Rule out recurrence of cancer • Inquire about fi t  ...  bacterial capsular polysaccharide, inactivated polio vaccine (IPV), Japanese encephalitis, and rabies virus are recommended by the Centers for Disease Control and Prevention (www.cdc.gov). 8 Folaranmi T,  ... 
doi:10.6004/jnccn.2018.0078 pmid:30323092 pmcid:PMC6438378 fatcat:jg7y3pawbzgsfcwukzjl3ryn5q

NCCN Guidelines Insights: Survivorship, Version 1.2016

Crystal S. Denlinger, Jennifer A. Ligibel, Madhuri Are, K. Scott Baker, Gregory Broderick, Wendy Demark-Wahnefried, Debra L. Friedman, Mindy Goldman, Lee W. Jones, Allison King, Grace H. Ku, Elizabeth Kvale (+22 others)
2016 The Journal of the National Comprehensive Cancer Network  
The NCCN Guidelines for Survivorship provide screening, evaluation, and treatment recommendations for common consequences of cancer and cancer treatment. They are intended to aid health care professionals who work with survivors of adult-onset cancer in the posttreatment period, including those in general oncology, specialty cancer survivor clinics, and primary care practices. Guidance is also provided to help promote physical activity, weight management, and proper immunizations in survivors.
more » ... his article summarizes the NCCN Survivorship panel's discussions for the 2016 update of the guidelines regarding the management of anxiety, depression, posttraumatic stress disorder-related symptoms, and emotional distress in survivors. Continuing Education, NCCN, has disclosed that she has no relevant financial relationships. Ann Gianola, MA, Senior Manager, Continuing Education Accreditation & Program Operations, NCCN, has disclosed that she has no relevant financial relationships. Kristina M. Gregory, RN, MSN, OCN, Vice President, Clinical Information Operations, NCCN, has disclosed that she has no relevant financial relationships. Rashmi Kumar, PhD, Senior Manager, Clinical Content, NCCN, has disclosed that she has no relevant financial relationships. Individuals Who Provided Content Development and/or Authorship Assistance: Crystal S. Denlinger, MD, Panel Chair, has disclosed that she is a scientific advisor for Eli Lilly and Company and Merrimack Pharmaceuticals. Jennifer A. Ligibel, MD, Panel Vice Chair, has disclosed that she has received a product donation from Fitbit for a research study. Madhuri Are, MD, Panel Member, has disclosed that she has no relevant financial relationships. Grace H. Ku, MD, Panel Member, has disclosed that she has no relevant financial relationships. Elizabeth Kvale, MD, Panel Member, has disclosed that she is a consult for Aspire Healthcare. Mary S. McCabe, RN, BS, MA, Panel Member, has disclosed that she has no relevant financial relationships. Mary Ann Morgan, PhD, FNP-BC, Panel Member, has disclosed that she is on the speakers' bureau for Genentech. Electra D. Paskett, PhD, Panel Member, has disclosed that she has equity interest/stock options from Pfizer Inc, and receives grant/research support from Merck & Co., Inc. Jeffrey Peppercorn, MD, MPH, Panel Member, has disclosed that he has equity interest/stock options and receives salary from GlaxoSmith-Kline, and receives grant/research support from Pfizer Inc. Kathryn J. Ruddy, MD, MPH, Panel Member, has disclosed that she has no relevant financial relationships. Tara Sanft, MD, Panel Member, has disclosed that she has no relevant financial relationships. Karen L. Syrjala, PhD, Panel Member, has disclosed that she has no relevant financial relationships. Nicole R. McMillian, MS, Guidelines Coordinator, NCCN, has disclosed that she has no relevant financial relationships. Deborah A. Freedman-Cass, PhD, Oncology Scientist/Senior Medical Writer, NCCN, has disclosed that she has no relevant financial relationships. • The NCCN Guidelines for Distress Management defi ne distress as "a multifactorial unpleasant emotional experience of a psychological (ie, cognitive, behavioral, emotional), social, and/or spiritual nature that may interfere with the ability to cope effectively with cancer, its physical symptoms, and its treatment." • Survivors of cancer treatment are at high risk for fear of recurrence, distress, anxiety, and depression due to the multiple challenges they face. Fear of recurrence can lead to increased symptoms when surveillance testing or follow-up appointments are scheduled and increased anxiety when physical symptoms occur that may or may not be similar to those experienced during the cancer diagnosis. Medical, psychosocial, environmental, and psychiatric health factors may affect the mood of cancer survivors and need to be considered when screening for distress, anxiety, and depression in survivors and deciding on treatment. (See SANXDE-6) Recurrent worry, fear, thoughts, or images related to cancer events should be distinguished from obsessive compulsive disorders. Repetitive, persisting thoughts, images, or behaviors or mental acts that a person is compelled to perform, aimed at reducing intense anxiety or preventing a dreaded event require psychiatric referral for evaluation and treatment. Monitor distress, especially at times of transitions in care, cancer surveillance, signifi cant loss, other major life events, and with social isolation. ◊ Patients may not appear to be distressed and should be encouraged to inform their health care provider when they are feeling increased distress, anxiety, or depression. See DIS-B from the NCCN Guidelines for Distress Management.
doi:10.6004/jnccn.2016.0073 pmid:27283164 pmcid:PMC5865597 fatcat:ov5cz34iyngzjnu4263mtfdkca

A multi-modal intervention for Activating Patients at Risk for Osteoporosis (APROPOS): Rationale, design, and uptake of online study intervention material

Maria I. Danila, Ryan C. Outman, Elizabeth J. Rahn, Amy S. Mudano, Tammi F. Thomas, David T. Redden, Jeroan J. Allison, Fred A. Anderson, Julia P. Anderson, Peter M. Cram, Jeffrey R. Curtis, Liana Fraenkel (+13 others)
2016 Contemporary Clinical Trials Communications  
., student t tests and chi square tests) and stepwise multivariable logistic regression were used to evaluate differences in uptake of the intervention by sociodemographic characteristics and type of contact  ... 
doi:10.1016/j.conctc.2016.06.010 pmid:27453960 pmcid:PMC4955389 fatcat:gynak7l6ojexrcoqw6xkqhybgi

Survivorship, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology

Crystal S. Denlinger, Tara Sanft, K. Scott Baker, Shrujal Baxi, Gregory Broderick, Wendy Demark-Wahnefried, Debra L. Friedman, Mindy Goldman, Melissa Hudson, Nazanin Khakpour, Allison King, Divya Koura (+22 others)
2017 The Journal of the National Comprehensive Cancer Network  
of black cohosh for vasomotor symptoms in the general population; however, randomized data in breast cancer survivors show no benefi t. www.ncbi.nlm.nih.gov/pubmed/16782922 *Available online, in these  ...  appropriate specialist for management i Compounds with limited evidence of safety and effi cacy (all category 2B) j • Phytoestrogens • Botanicals • Dietary supplements Limited data show a possible benefi t  ... 
doi:10.6004/jnccn.2017.0146 pmid:28874599 pmcid:PMC5865602 fatcat:znypwvulcvcgvlwa6ohlll7u6i

Page 38 of Academe Vol. 2, Issue 6 [page]

1916 Academe  
Silverman) Charles H. Posty (Physics), College of the City of New York, (C. Baskerville, 8. P. Duggan, H. A. Overstreet) Vernon L. Parrington (English), University of Washington, (W. F. Allison, O.  ...  T., H. M. Goodwin, M. I. T., H. W. Tyler, M. I. T)) Paul Cook Nugent (Engineering), Syracuse, (C. H. Richardson, C. W. Hargitt, H. A. Eaton) Charles Cleveland Nutting (Zoédlogy), Iowa, (C. F.  ... 

Page 2439 of Psychological Abstracts Vol. 80, Issue 5 [page]

1993 Psychological Abstracts  
Arturo, 17827 Silva, Phil A., 18057 Silver, Daniel H., 17305 Silver, Wayne L., com Silverman, Barry G., Silverman, David G., rr’ 19219 Silverman, Franklin i, 2 Silverman, Kenneth, 17428 Silverman, Phyllis  ...  R., 17182 Silverstein, Louis D., 16179, 16210 Silverstone, T., 18712, 18776 Silvestri, Vito N., Simizu, Koru, 17036 Simon, Walter T., 18076 Simonds, Susan L., 18490 Simons, Yaron, 19772 Simonsson, P.,  ... 

Page 16 of Academe Vol. 4, Issue 5 [page]

1918 Academe  
Silverman, J. M. Mecklin, B. L. Ullman) Frances G. Wick (Physics), Vassar, (L. E. Textor, E. Ellery, H. 8. White)  ...  Allison, F. C. French) Arthur G. Robbins (Civil Engineering), Mass. Inst. of Technology, (H. P. Talbot, R. 8. Williams, H. W. Tyler) George Lucas Roberts (Education), Purdue, (E. H. Davis, M. L.  ... 

Page 188 of Journal of the American Ceramic Society Vol. 14, Issue 6 [page]

1931 Journal of the American Ceramic Society  
Allison, Ceramic Age, Newark; N. J. ; F. A. Guignon, Ceramic Industry, Chicago, II. J. E. Randall, Clay-Worker, Indianapolis, Ind.  ...  T. Vanderbilt Co., New York, N. Y. { F. P. Nickerson, W. S. Tyler Co., Cleveland, Ohio. Ways and Means: 1G. T. Stowe, Sierra-Magnesite Co., Cleveland, Ohio. | R. D. Landrum, Titanium Alloy Mfg.  ... 

Page 646 of Contemporary Psychology Vol. 47, Issue 5 [page]

2002 Contemporary Psychology  
Friedman, Ellen T. AMERICAN lilustrated by Cary Pillo, Allison G. Harvey Gerrity, and Raymond M. Scurfield PSYCHOLOGICAL Afterword by Sasha J. Mudiatt oe 2000. 251 pages. Hardcover, 1996. 576 pages.  ...  Silverman, Eric M. Vernberg, and Michael C.  ... 

Page 878 of Journal of Cognitive Neuroscience Vol. 20, Issue 5 [page]

2008 Journal of Cognitive Neuroscience  
Nakayama, K., Shimojo, S., & Silverman, G.  ...  ., & Allison, T. (1999) Electrophysiological studies of human face perception: II Response properties of face-specific potentials generated in Occipitotemporal cortex.  ... 

Page 145 of American Anthropologist Vol. 116, Issue 1 [page]

2014 American Anthropologist  
Isbell and Pelaine Silverman, eds, Pp. 258 278.  ...  Washington, DC: Smithsonian Institution, Wie, Allison 200? The Reaction against: Analogy, Jn Thinking trom Things: Pssavs in the Philosophy of Archaeology. Allison Wylie. ed, Mp. 136 153.  ... 

Page 1747 of None Vol. 37, Issue 12 [page]

1931 None  
Allison, V. J. Andrew—1717(A) Ionization in dielectrics, J. T. Tykociner, E. B. Paine—1690(A) Kundt’s tube dust figures, E. Hutchisson, F. B. Morgan—1155 Latent image at low intensities, F. E.  ...  Shugart— 1683(A) X-ray powder diffraction, T. M.  ... 

Page 808 of Journal of Biological Chemistry. [Filmed From the Online Edition] Vol. 183, Issue 1 [page]

1950 Journal of Biological Chemistry. [Filmed From the Online Edition]  
See Lorber, Lifson, Wood, Sakami, and Shreeve, 517 Silverman, Milton. See Keresztesy and Silverman, 473 Simmonds, Sofia, Keller, Elizabeth B., Chandler, joseph P., and du Vigneaud, Vincent.  ...  ., and Allison, James B. The effects of feeding excess DL- methionine and choline chloride to rats on a casein diet, 173 Russell, Peter B.  ... 

Page 138 of Geophysics Vol. 13, Issue 1 [page]

1948 Geophysics  
Peterson Ernest Allison Pratt Sidon Harris, Paul Ledyard, R. H. Dana Miller Winthrop Quarles, Jr. Norman J. Christie, C. H. Dix, R. A.  ...  Silverman Gaulvin A. Parker C. A. Swartz, J. W. Horn, M. P. Jones John Parker Paschall W. J. Osterhoudt, W. B. Lee Jr., P. M. Konkel Sam M. Pefia P. J. Rudolph, W. Harlan Taylor, C. D.  ... 
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