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Alexandre Dufour (1759-1835), architecte de Versailles
2019
Bulletin du Centre de Recherche du Château de Versailles
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Dufour Alexandre, architecte P.F.L. Fontaine. Aquarelle, 27 × 107 cm. MV8928 ; invdessins 1113. ...
Dufour Alexandre, architecte P.F.L. Fontaine. Aquarelle, 32 × 91,5 cm. MV 9135, invdessins 1258. ...
doi:10.4000/crcv.16208
fatcat:ixxdmdj2q5gvzlgrmunbfnselq
CHRONIQUE DE JURISPRUDENCE QUÉBÉCOISE PORTANT SUR LE DROIT INTERNATIONAL PRIVÉ
2006
Revue québécoise de droit international
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CHRONIQUE DE JURISPRUDENCE QUÉBÉCOISE PORTANT SUR LE DROIT INTERNATIONAL PRIVÉ Par Richard Dufour * , Geneviève Dufour ** et Alexandre Morin *** L'étude de la jurisprudence en droit international privé ...
Le législateur québécois interdit désormais aux commerçants d'inclure une clause d'arbitrage dans * Avocat; associé principal au Cabinet Dufour Mottet. ...
doi:10.7202/1069111ar
fatcat:7y36qrqdyvezbbgigbw3yvllha
Tracking algorithms chase down pathogens
2009
Biotechnology Journal
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Understanding sub-cellular dynamic processes governing pathogenic mechanisms is a necessary step towards the development of new drugs and strategies against infectious diseases. Sub-cellular pathogenic mechanisms, such as viral invasion processes involve highly dynamic nano-metric scale objects and rapid molecular interactions that require the study of individual particle paths. Single particle tracking methods allow to visualize and characterize the dynamics of biological objects and provide a
doi:10.1002/biot.200900030
pmid:19548236
fatcat:3lwppkwkf5a65oijoeyqlnzkhi
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... straightforward and accurate means to understand sub-cellular processes. This review describes a number of particle tracking methods in time-lapse microscopy sequences and provides examples of using such techniques to investigate mechanisms of host-pathogen interactions.
3D Mumford-Shah Based Active Mesh
[chapter]
2006
Lecture Notes in Computer Science
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Deformable mesh methods have become an alternative of choice to classical deformable models for 3D image understanding. They allow to render the evolving surface directly during the segmentation process in a fast and efficient way, avoiding both the additional timecost and approximation errors induced by 3D reconstruction algorithms after segmentation. Current methods utilize edge-based forces to attract the mesh surface toward the image entities. These forces are inadequate in 3D fluorescence
doi:10.1007/11892755_21
fatcat:tj2g6j3fr5gfnjlwkghrcuqcba
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... icroscopy, where edges are not well defined by gradient. In this paper, we propose a fully automated deformable 3D mesh model that deforms using the reduced Mumford-Shah functional to segment and track objects with fuzzy boundaries. Simultaneous rendering of the mesh evolution allows faster tweaking of the model parameters and offers biologists a more precise insight on the scene and hence better understanding of biological phenomena. We present evaluations on both synthetic and real 3D microscopy data.
Jean-Guy Lacroix et Jacques-Alexandre Mascotto, Manifeste pour l'humanité, Montréal, Lanctôt Éditeur, 2000, 144 p
2000
Cahiers de recherche sociologique
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Guillaume DUFOUR Étudiant à la maîtrise en science politique Université du Québec à Montréal ...
Le manifeste de deux professeurs au département de sociologie de l'Université du Québec à Montréal (UQAM), Jacques-Alexandre Mascotto et Jean-Guy Lacroix, rompt avec cette position de repli en se situant ...
doi:10.7202/1002432ar
fatcat:ewa5tme7izbz3mdt27r5tz5aoy
Mapping molecular assemblies with fluorescence microscopy and object-based spatial statistics
2018
Nature Communications
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A Multimodal Micro-Optrode Combining Field and Single Unit Recording, Multispectral Detection and Photolabeling Capabilities
2013
PLoS ONE
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Microelectrodes have been very instrumental and minimally invasive for in vivo functional studies from deep brain structures. However they are limited in the amount of information they provide. Here, we describe a, aluminum-coated, fibre optic-based glass microprobe with multiple electrical and optical detection capabilities while retaining tip dimensions that enable single cell measurements (diameter #10 mm). The probe enables optical separation from individual cells in transgenic mice
doi:10.1371/journal.pone.0057703
pmid:23469053
pmcid:PMC3585187
fatcat:2zp7urwqurcx5db7b5vslef464
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... ng multiple fluorescent proteins in distinct populations of neurons within the same deep brain nucleus. It also enables color conversion of photoswitchable fluorescent proteins, which can be used for post-hoc identification of the recorded cells. While metal coating did not significantly improve the optical separation capabilities of the microprobe, the combination of metal on the outside of the probe and of a hollow core within the fiber yields a microelectrode enabling simultaneous single unit and population field potential recordings. The extended range of functionalities provided by the same microprobe thus opens several avenues for multidimensional structural and functional interrogation of single cells and their surrounding deep within the intact nervous system.
CHRONIQUE DE JURISPRUDENCE QUÉBÉCOISE PORTANT SUR LE DROIT INTERNATIONAL PRIVÉ
2004
Revue québécoise de droit international
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. ** Me Richard Dufour est avocat, membre du Barreau du Québec et associé du Cabinet Dufour Mottet à Laval. 1 P.L. ...
Telle était la question que le tribunal * Me Alexandre Morin est avocat et membre du Barreau du Québec. ...
doi:10.7202/1069255ar
fatcat:54nr26qyojf4ng3v6expu2umyy
CHRONIQUE DE JURISPRUDENCE QUÉBÉCOISE PORTANT SUR LE DROIT INTERNATIONAL PRIVÉ
2007
Revue québécoise de droit international
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Tous droits réservés © Société québécoise de droit international, 2007 Ce document est protégé par la loi sur le droit d'auteur. L'utilisation des services d'Érudit (y compris la reproduction) est assujettie à sa politique d'utilisation que vous pouvez consulter en ligne. https://apropos.erudit.org/fr/usagers/politique-dutilisation/ Cet article est diffusé et préservé par Érudit. Érudit est un consortium interuniversitaire sans but lucratif composé de l
doi:10.7202/1068982ar
fatcat:s5mduk6clrf6zhlvm27xxldqxm
Surface tension measurements with a smartphone
2017
The Physics Teacher
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Goy, Zakari Denis, Maxime Lavaud, Adrian Grolleau, Nicolas Dufour, Antoine Deblais, and Ulysse Delabre, University of Bordeaux, France S martphones are increasingly used in higher education and at university ...
experiment is an iPhone 4s (camera sensor 8 MPixels, display 6403960 pixels, 3.5-in screen) and the standard camera function of the smartphone
Surface tension measurements with a smartphone Nicolas-Alexandre ...
doi:10.1119/1.5008349
fatcat:ubuk22xfpbfuvpnzll4vlcs27u
Icy: A User-Friendly Environment For Algorithm Development And Deployment
2013
Zenodo
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Publication in the conference proceedings of EUSIPCO, Marrakech, Morocco, 2013
doi:10.5281/zenodo.43665
fatcat:pit2zun7wfh6fng4vkdnguenvi
Methacrylated Cartilage ECM-Based Hydrogels as Injectables and Bioinks for Cartilage Tissue Engineering
2022
Biomolecules
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Articular cartilage (AC) possesses a limited healing potential, meaning that untreated focal joint defects typically progress, leading to the development of degenerative diseases such as osteoarthritis. Several clinical strategies exist that aim to regenerate AC; however, recapitulation of a fully functional, load-bearing tissue remains a significant challenge. This can be attributed, at least in part, to a paucity of biomaterials that truly mimic the native tissue and provide appropriate cues
doi:10.3390/biom12020216
pmid:35204718
pmcid:PMC8961582
fatcat:xq6r4akohra47d5xvbhkpzxg3a
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... o direct its regeneration. The main structural component of articular cartilage, type II collagen, does not readily gelate at body temperature, challenging the development of cartilage extracellular matrix (cECM)-derived injectable hydrogels and bioinks for AC tissue engineering and bioprinting applications. Here, we describe the development and rheological characterisation of a methacrylated cartilage ECM-based hydrogel/bioink (cECM-MA), which could be photocrosslinked when exposed to ultraviolet (UV) light. Functionalisation of the collagen backbone with methacryloyl groups had a negligible effect on triple helix stability, as demonstrated by circular dichroism spectroscopy. These cECM-MA bioinks demonstrated shear-thinning properties and could be loaded with bone marrow mesenchymal stem cells (BM-MSCs), micro-extruded to generate self-supporting 3D constructs of predefined size and shape, and then photocrosslinked using UV light. Analysis of the cell-laden constructs showed that the BM-MSCs were viable post-printing and underwent chondrogenesis in vitro, generating a tissue rich in sulphated glycosaminoglycans and collagens. These results support the use of methacrylated, tissue-specific ECM-derived hydrogels as bioinks for 3D bioprinting and/or as injectables for cartilage tissue engineering applications.
Optimization of Preservation Methods Allows Deeper Insights into Changes of Raw Milk Microbiota
2020
Microorganisms
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The temporal instability of raw milk microbiota drastically affects the reliability of microbiome studies. However, little is known about the microbial integrity in preserved samples. Raw cow milk samples were preserved with azidiol or bronopol and stored at 4 °C, or with dimethyl sulfoxide (DMSO) or a mixture of azidiol and DMSO and stored at −20 °C for up to 30 days. Aliquots of 5-, 10-, and 30-day post-storage were treated with propidium monoazide (PMA), then analyzed by sequencing the 16S
doi:10.3390/microorganisms8030368
pmid:32151050
pmcid:PMC7142718
fatcat:npt7jyyw5ncn5ouigsj2lfuife
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... NA gene V3-V4 and V6-V8 regions. The V6-V8 gave a higher richness and lower diversity than the V3-V4 region. After 5-day storage at 4 °C, the microbiota of unpreserved samples was characterized by a drastic decrease in diversity, and a significant shift in community structure. The treatment with azidiol and DMSO conferred the best community stabilization in preserved raw milk. Interestingly, the azidiol treatment performed as well for up to 10 days, thus appearing as a suitable alternative. However, neither azidiol nor bronopol could minimize fungal proliferation as revealed by PMA-qPCR assays. This study demonstrates the preservative ability of a mixture of azidiol and DMSO and provides deeper insights into the microbial changes occurring during the cold storage of preserved raw milk.
Integrating melt-electrowriting and inkjet bioprinting for engineering structurally organized articular cartilage
[article]
2021
bioRxiv
pre-print
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Successful cartilage engineering requires the generation of biological grafts mimicking the structure, composition and mechanical behaviour of the native tissue. Here melt-electrowriting (MEW) was used to produce arrays of polymeric structures whose function was to orient the growth of cellular aggregates spontaneously generated within these structures, and to provide tensile reinforcement to the resulting tissues. Inkjeting was used to deposit defined numbers of cells into MEW structures,
doi:10.1101/2021.10.24.465623
fatcat:qdioi2j3frdyvpacekkwaqjd44
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... self-assembled into an organized array of spheroids within hours, ultimately generating a hybrid tissue that was hyaline-like in composition. Structurally, the engineered cartilage mimicked the histotypical organization observed in skeletally immature synovial joints. This biofabrication framework was then used to generate scaled-up (50mm x 50mm) cartilage implants containing over 3,500 cellular aggregates in under 15 minutes. After 8 weeks in culture, a 50-fold increase in the compressive properties of these MEW reinforced tissues were observed, while the tensile properties were still dominated by the polymer network, resulting in a composite construct demonstrating tension-compression nonlinearity mimetic of the native tissue. Helium ion microscopy further demonstrated the development of an arcading collagen network within the engineered tissue. This hybrid bioprinting strategy provides a versatile and scalable approach to engineer cartilage biomimetic grafts for biological joint resurfacing.
On the expected total reward with unbounded returns for Markov decision processes
[article]
2018
arXiv
pre-print
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We consider a discrete-time Markov decision process with Borel state and action spaces. The performance criterion is to maximize a total expected utility determined by unbounded return function. It is shown the existence of optimal strategies under general conditions allowing the reward function to be unbounded both from above and below and the action sets available at each step to the decision maker to be not necessarily compact. To deal with unbounded reward functions, a new characterization
arXiv:1712.07874v2
fatcat:towv6vshajejxayqvm6g3bvmx4
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... or the weak convergence of probability measures is derived. Our results are illustrated by examples.
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