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Sources and implications of deep uncertainties surrounding sea-level projections
2016
Climatic Change
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The continuous lines are fitted beta-distributions assuming an 3.3-m (i.e., total disintegration) upper limit. ...
From a robust decision-making perspective, conservative projections may be preferable to overconfident projections (see for example the discussions in Herman et al. 2015 and Bakker et al. 2016 Fig. ...
doi:10.1007/s10584-016-1864-1
fatcat:k22ml5dfefc4pkd7o3tbnaptsa
Slow fertilization of stickleback eggs: the result of sexual conflict?
2006
BMC Ecology
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TCMB & M. ...
In fish of the Texel population sperm number in left and right testes were not significantly different (paired t test, t = 0.90, df = 12, P = 0.39) and correlated well (r p = 0.72, N = 12, P = 0.009) ( ...
doi:10.1186/1472-6785-6-7
pmid:16712724
pmcid:PMC1481549
fatcat:ebfwkdsv2bggtibxyox3pq456m
The effects of time-varying observation errors on semi-empirical sea-level projections
2016
Climatic Change
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The projected 90% probability ranges in 2050 differ by up to 0.11 m; Bootstrap (0.23-0.33 m), homoskedastic Bayesian (0.19-0.32 m), to heteroskedastic Bayesian (0.14-0.35 m) (Fig. 2c) . ...
0.42 m; this difference corresponds to a 40% increase (Fig. 4f) . ...
doi:10.1007/s10584-016-1858-z
fatcat:3y6pmg5eafa6pmaegwxucpdqke
Estimation of persistence and trends in geostrophic wind speed for the assessment of wind energy yields in Northwest Europe
2011
Climate Dynamics
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M. R. Bakker, B. J. J. M van den Hurk: Persistence and trends in wind climate in Northwest Europe 771 using the slp-gradient between the four surrounding grid points. ...
A distinct increase has been reported from the 1960s until the mid 1990s (Pryor and Barthelmie 2003; Alexander et al. 2005) . ...
doi:10.1007/s00382-011-1248-1
fatcat:rlyme72a3rb77fmf5cyvpexmmm
Sea-level projections representing the deeply uncertain contribution of the West Antarctic ice sheet
2017
Scientific Reports
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The probabilistic part of the sea-level projections for 2050 yields 90% credible ranges of 0.19-0.32 m (RCP2.6), 0.21-0.34 m (RCP4.5), and 0.23-0.37 m (RCP8.5) sea level relative to 1986-2005 mean sea ...
This GIS contribution increases the 90% credible ranges for 2100 to 0.40-0.71 m (RCP2.6), 0.54-0.97 m (RCP4.5), and 0.85-1.59 m (RCP8.5) sea level in 2100, relative to 1986-2005 mean sea level (Fig. 2 ...
Bakker and K. Keller designed the research. A. Bakker designed the initial figures and wrote the first draft. T. Wong and K. Ruckert took care of the major part of the coding. ...
doi:10.1038/s41598-017-04134-5
pmid:28634375
pmcid:PMC5478629
fatcat:5xgyz2wm55ey3md4b2mxfj5zsy
IR photofragmentation of the Phenyl Cation: Spectroscopy and Fragmentation Pathways
2021
Physical Chemistry, Chemical Physics - PCCP
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We present the gas-phase infrared spectra of the phenyl cation, phenylium, in its perprotio C6H5+ and perdeutero C6D5+ forms, in the 260--1925 cm-1 (5.2-38 μm) spectral range, and investigate the... ...
The m/z = 50 and 49 channels appear mostly along this dominant m/z = 51 mass, while the m/z = 37 channel only appears at the most intense resonances. ...
Four fragment ions are observed at m/z =51, 50, 49 and 37 in addition to the parent ion at m/z = 77. ...
doi:10.1039/d0cp05554a
pmid:33587740
fatcat:umnisuzwq5gkjld4mjfsgqt3ky
BRICK v0.2, a simple, accessible, and transparent model framework for climate and regional sea-level projections
2017
Geoscientific Model Development
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BRICK is written in R and Fortran. ...
R Core Team, 2016). ...
of mass on the Antarctic Ice Sheet (m 3 yr −1 ), T A is the Antarctic surface temperature reduced to sea level ( • C), S is the sea level (m), R is the Antarctic Ice Sheet radius (m), and F is the ice ...
doi:10.5194/gmd-10-2741-2017
fatcat:mzvklxihd5emvgtnihymxfjguq
Large-scale winds in the southern North Sea region: the wind part of the KNMI'14 climate change scenarios
2015
Environmental Research Letters
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Res. 14 71-3 Bakker A M R and van den Hurk B J J M 2012 Estimation of persistence and trends in geostrophic wind speed for theassessment of wind energy yields in Northwest Europe Clim. ...
Dyn. 39 767-82 Bakker A M R, van den Hurk B J J M and Coelingh J P 2013 Decomposition of the windiness index in the Netherlands for the assessment of future long-term wind supply Wind Energy 16 927-36 ...
doi:10.1088/1748-9326/10/3/035004
fatcat:bz75q4qypfhozigi7z6wol655e
Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose
2018
Investigational new drugs
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Software Data management, graphical evaluation and simulations were performed using R (version 3.0.1) [16] . ...
This K m is in the same order of magnitude as the K m of MCLA-128 used in the sensitivity analysis (2.19 mg/L). ...
Compliance with ethical standards Conflict of interest Robert Doornbos, Alexander Bakker, Kees Bol, Mark Throsby, Cecile Geuijen and David Maussang are employees of Merus N.V. ...
doi:10.1007/s10637-018-0593-x
pmid:29728897
fatcat:nmnjlhmws5avvhgnevu6xvkhme
Evaluation of dextran(ethylene glycol) hydrogel films for giant unilamellar lipid vesicle production and their application for the encapsulation of polymersomes
2017
Soft Matter
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As a comparison, we also determined the T m of DOPC in the presence of a gel consisting solely of disulphide crosslinked PEG (2 wt% of 5). ...
The melting temperature (T m ) of DOPC lipids in the presence and absence of the DexPEG film was determined by differential scanning calorimetry (DSC). ...
doi:10.1039/c7sm00551b
pmid:28730206
pmcid:PMC5586486
fatcat:4i5ecanhurgubp73auznqkba3q
Packaging signals in single-stranded RNA viruses: nature's alternative to a purely electrostatic assembly mechanism
2013
Journal of biological physics (Print)
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This effect is reduced when we compare discrimination of MS2 and STNV RNAs at typical in vitro reassembly concentrations (≥10 μM) [14] . ...
nanomolar concentrations range (∼1 nM for RNA & ∼100 nM for CP), which are much more reflective of early concentrations within infected cells than most in vitro assays where CP concentrations of ≥10 μM ...
doi:10.1007/s10867-013-9313-0
pmid:23704797
pmcid:PMC3662417
fatcat:sobmmfbknfg7dj3kxj7gdpx3xm
Snake Venom Gland Organoids
2020
Cell
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Maimets, M., Rocchi, C., Bron, R., Pringle, S., Kuipers, J., Giepmans, B.N., Vries, R.G., Clevers, H., de Haan, G., van Os, R., and Coppes, R.P. (2016). ...
doi:10.1016/j.cell.2019.11.038
pmid:31978343
fatcat:2zsqrasdhjfkvdqadabu7oy5nq
Impacts of Antarctic fast dynamics on sea-level projections and coastal flood defense
2017
Climatic Change
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2017 pre-print arXiv:1612.07175v2 fatcat:cb5qnocnbjdmrllqpsqnhmbz7mOther Versions
The physical models are coded in Fortran 90 and called from driver scripts coded in the R Programming Language. The analysis was performed using RStudio (Version 0.99.903). ...
,000 years BCE, -11.35 m SLE, 2.23 m SLE; 4,000 years BCE, -2.63 m SLE, 0.68 m SLE; and 2002 CE, 0.00197 m SLE, 0.00046 m SLE
Table
. ...
(a) surface temperature anomaly (C), (b) ocean heat uptake (10 22 J), (c) glaciers and small ice caps (m SLE), (d) Greenland Ice Sheet (m SLE), (e) thermal expansion (m SLE), (f) total sea level (m SLE ...
doi:10.1007/s10584-017-2039-4
fatcat:b7zevqiopnfmtoil4sgdvvzvze
Pancreatitis, very early compared with normal start of enteral feeding (PYTHON trial): design and rationale of a randomised controlled multicenter trial
2011
Trials
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Dutch Pancreatitis Study Grp (2011). Pancreatitis, very early compared with normal start of enteral feeding (PYTHON trial): design and rationale of a randomised controlled multicenter trial. TRIALS, 12, [73]. Abstract Background: In predicted severe acute pancreatitis, infections have a negative effect on clinical outcome. A start of enteral nutrition (EN) within 24 hours of onset may reduce the number of infections as compared to the current practice of starting an oral diet and EN if
doi:10.1186/1745-6215-12-73
pmid:21392395
pmcid:PMC3068962
fatcat:v2j7u6d5sran7bq67rlpk2ihuq
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... at 3-4 days after admission. Methods/Design: The PYTHON trial is a randomised controlled, parallel-group, superiority multicenter trial. Patients with predicted severe acute pancreatitis (Imrie-score ≥ 3 or APACHE-II score ≥ 8 or CRP > 150 mg/L) will be randomised to EN within 24 hours or an oral diet and EN if necessary, after 72 hours after hospital admission. During a 3-year period, 208 patients will be enrolled from 20 hospitals of the Dutch Pancreatitis Study Group. The primary endpoint is a composite of mortality or infections (bacteraemia, infected pancreatic or peripancreatic necrosis, pneumonia) during hospital stay or within 6 months following randomisation. Secondary endpoints include other major morbidity (e.g. new onset organ failure, need for intervention), intolerance of enteral feeding and total costs from a societal perspective. Discussion: The PYTHON trial is designed to show that a very early (< 24 h) start of EN reduces the combined endpoint of mortality or infections as compared to the current practice of an oral diet and EN if necessary at around 72 hours after admission for predicted severe acute pancreatitis.
A cryogenic imaging x-ray spectrometer for XEUS readout by frequency-division SQUID multiplexers
2004
High-Energy Detectors in Astronomy
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Measurements indicate that the phonon mfp is 110 µm for a 40 µm wide Si-beam. ...
For R ESR ≈ 1 mΩ the Q-factor (1/Q = ωCR ESR ) of the capacitors has to be between 670 and 6700 for carrier frequencies between 1 and 10 MHz, respectively. ...
doi:10.1117/12.552933
fatcat:6z53qg6htzgp7lt6n6py5pcfiy
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