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EXPERIMENTAL AND CLINICAL STUDIES ON T-1982
T-1982の基礎的, 臨床的検討
1982
Chemotherapy
T-1982の基礎的, 臨床的検討
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Experimental and clinical studies on T-1982 were performed to evaluate usefulness in the field of oral surgery. T-1982 was administered to rabbits at a dose of 33 mg/kg by 2 hour i.v. drip infusion. ...
Twenty patients with oral purulent inflammation were treated with T-1982 at a daily dose of 1 to 2 g for 4 to 11 days. Clinical results were good in 19 cases and poor in 1 case. ...
T-1982は1回19,1日2回 点 滴 静 注 し,初 診 時 の 症 状 評 点30点 で あ っ た もの が,投 与3日 後 の 評 点20点 (評 点 比0.67)と 効 果 が み られ た 。 本 症 例 で は,T-1982は11日 間22gが 使 用 さ れ た 。 ...
doi:10.11250/chemotherapy1953.30.supplement3_961
fatcat:455ulu3ofrh25c6rvczh263ifa
Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals
2020
Nutrients
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Our double-blind, placebo-controlled study evaluated effects of ubiquinol, the reduced form of coenzyme Q10, on mild fatigue in healthy individuals experiencing fatigue in daily life that had continued for more than 1 and less than 6 months. The participants received 100-mg/day (Ubq100; age 44.0 ± 9.8 years; 14 females and 6 males) or 150-mg/day ubiquinol (Ubq150; age 40.4 ± 11.8 years; 14 females and 8 males) or placebo (Plc; age 41.3 ± 13.4 years; 13 females and 7 males) daily for 12 weeks.
doi:10.3390/nu12061640
pmid:32498248
fatcat:lyhsyc2y45de3gesexvhuhuosq
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... asurements of subjective and objective fatigue were conducted by using questionnaires-based fatigue scales/visual analogue scales and autonomic nerve function/biological oxidation index, respectively, prior to the first dosing and every 4 weeks thereafter. Serum ubiquinol level increased three- to four-fold after 4 weeks and remained significantly higher than that after Plc administration throughout the intake period. Although a higher blood level of ubiquinol was observed with Ubq150 than with Ubq100, the difference was not statistically significant. In both Ubq100 and Ubq150 groups, subjective levels of fatigue sensation and sleepiness after cognitive tasks, which consisted of the modified Advanced Trail Making Test, the modified Stroop Color-Word Test, and the Digit Symbol Substitution Test, improved significantly compared with those in the placebo group, suggesting an anti-fatigue effect. The Ubq150 group demonstrated significant improvement compared with the Plc group regarding subjective level of relaxation after task, sleepiness before and after task, motivation for task, and serum level of oxidative stress. Correlation analysis between blood level of ubiquinol and each evaluated effect suggested a positive relationship with relaxation after task, motivation for cognitive task, and parasympathetic activity. The results of the study suggest that ubiquinol intake relieves mild fatigue in healthy individuals.
EXPERIMENTAL AND CLINICAL STUDIES OF T-3262 IN ORAL SURGERY
口腔外科領域におけるT-3262の基礎的, 臨床的検討
1988
Chemotherapy
口腔外科領域におけるT-3262の基礎的, 臨床的検討
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Clinical response of T-3262 classified by diagnosis Table 7. Clinical response of T-3262 classified by daily dose ...
血 清 中 濃 度 のparameter は 食 後 投 与 の 場 合T顯 。xは1.42hr,Cmaxは0.67 μ91ml,T(1/2)は3.28hr,Aucは4.17μ9・hr/mlで あ り,空 腹 時 投 与 で は 各 々1.67,0.61,2.36,3.30で あ っ た 。 ...
doi:10.11250/chemotherapy1953.36.supplement9-clinical_1488
fatcat:dde3yexdfbhebbmv2dhkxvokze
Mental fatigue is linked with attentional bias for sad stimuli
2019
Scientific Reports
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The design of the present study was dependent (paired), so that we used the equation advocated by Dunlap et al. 48 where t was the t statistic from paired samples t-test and r was the correlation across ...
The data from the paired samples t-test for each measure are also shown. df, degrees of freedom. ...
doi:10.1038/s41598-019-45428-0
pmid:31217505
pmcid:PMC6584697
fatcat:svtmbw2bencbncjhtrikukejqy
Frequency-specific network topologies in the resting human brain
2014
Frontiers in Human Neuroscience
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We then conducted two-tailed t-tests against the null-hypothesis that there were no group-level differences between I VLF and I LF in the calculated graph metrics. ...
Statistical comparisons For each threshold level, we conducted a two-tailed t-test with subjects (random effects analysis) against the null hypothesis, defined as no significant group-level difference ...
doi:10.3389/fnhum.2014.01022
pmid:25566037
pmcid:PMC4273625
fatcat:uvbgnoqpufcczohw4nym4vso7e
Bacteriological evaluation of T-3262(Tosufloxacin tosilate in the oral
口腔領域感染症に対するT‐3262(Tosufloxacin tosilate)の細菌学的検討
1989
ORAL THERAPEUTICS AND PHARMACOLOGY
口腔領域感染症に対するT‐3262(Tosufloxacin tosilate)の細菌学的検討
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T-3262 demonstrated high effectiveness on the isolated organisms. NFLX and ENX had little effectiveness on the isolated organisms. ...
Their susceptibilities to T-3262 (tosufloxacin tosilate), norfloxacine (NFLX), ofloxacin (OFLX) and enoxacin (ENX) were determined. The results were as follows. 1. ...
MICの 測 定 は 日 本 化 学 療 法 学 会 標 準 法1・2)に従 い,新 キ ノ ロ ン系 抗 菌 剤T。 ...
doi:10.11263/jsotp1982.8.16
fatcat:kdvpumehhjhk7boutqlcbycnty
Imaging the passionate stage of romantic love by dopamine dynamics
2015
Frontiers in Human Neuroscience
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The mean and standard deviation is shown in (B) and the P values resulted from statistical analysis by two-tailed paired t-test. ...
Statistical Analysis Differences between conditions for VAS parameters, physiological responses and BP ND (plots) were analyzed using a paired t-test. ...
Copyright © 2015 Takahashi, Mizuno, Sasaki, Wada, Tanaka, Ishii, Tajima, Tsuyuguchi, Watanabe, Zeki and Watanabe. ...
doi:10.3389/fnhum.2015.00191
pmid:25914637
pmcid:PMC4391262
fatcat:ucj65gc3hreflfjgvaqd7nkase
Neural networks for action representation: a functional magnetic-resonance imaging and dynamic causal modeling study
2012
Frontiers in Human Neuroscience
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T. ...
Sasaki) and by Scientific Research on Innovative Areas grant number 22101007 (Hiroki C. ...
STIMULUS PREPARATION
Original video clip An original video clip was recorded in which a ball was rotated once by the investigator (Akihiro T. ...
doi:10.3389/fnhum.2012.00236
pmid:22912611
pmcid:PMC3418609
fatcat:xxjc2yooergmtcmxu3phtpja2m
The role of prosody and context in sarcasm comprehension: Behavioral and fMRI evidence
2016
Neuropsychologia
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processing affective prosody in sarcasm comprehension, we created the following contrasts: the in- The resulting set of voxel values for each contrast constituted a statistical parametric mapping (SPM) of the t ...
doi:10.1016/j.neuropsychologia.2016.04.031
pmid:27157883
fatcat:gdfeyq3a3fecvppqkr2633fcha
Discovery of African bat polyomaviruses and infrequent recombination in the large T antigen in the Polyomaviridae
2017
Journal of General Virology
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Predicted coding regions for STAg (small T antigen), ALTO (alternate frame of the large T open reading frame), LTAg (large T antigen) and the variable protein (VP) 1-3 genes are indicated. ...
The PyV genome is functionally divided into an early region, encoding the small T antigen (STAg) and large T antigen (LTAg) nonstructural proteins, and a late region harbouring, minimally, the genes encoding ...
doi:10.1099/jgv.0.000737
pmid:28430100
fatcat:4jq6wr4p2bf3dnqz54jug6aium
Medial Prefrontal Cortex Activation Is Commonly Invoked by Reputation of Self and Romantic Partners
2013
PLoS ONE
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Izuma for providing experimental material and T. Kochiyama for helping with fMRI data analysis.
Author Contributions ...
doi:10.1371/journal.pone.0074958
pmid:24086409
pmcid:PMC3781163
fatcat:ndzdiexmfrdc5mphj56o5z6ck4
Low putamen activity associated with poor reward sensitivity in childhood chronic fatigue syndrome
2016
NeuroImage: Clinical
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The resulting set of voxel values for each comparison constituted a statistical parametric map of t statistics [SPM(t)]. ...
P values were obtained using Student's
t-test. ...
doi:10.1016/j.nicl.2016.09.016
pmid:27709065
pmcid:PMC5043413
fatcat:ir5bq2k7t5huhkax7igjmdnjuy
The anterior insular and anterior cingulate cortices in emotional processing for self-face recognition
2013
Social Cognitive and Affective Neuroscience
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30) ¼ 0.81, P ¼ 0.43; private: t(30) ¼ 1.50, P ¼ 0.14]. ...
increase of embarrassment when viewing face images of a partner [t(31) ¼ 1.88, P ¼ 0.07] or an unfamiliar person [t(31) ¼ 0.87, P ¼ 0.39] ( Figure 2B ). ...
doi:10.1093/scan/nst011
pmid:23377900
pmcid:PMC4014092
fatcat:lroxdjfjajg4tcpof22af3uiye
The Brain Mechanisms Underlying the Perception of Pungent Taste of Capsaicin and the Subsequent Autonomic Responses
2016
Frontiers in Human Neuroscience
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., 2003; Sasaki et al., 2013) . ...
statistic[SPM{t}]. ...
doi:10.3389/fnhum.2015.00720
pmid:26834613
pmcid:PMC4717328
fatcat:g4oubsyyrnf37n3i7xwuplveda
Perceiving active listening activates the reward system and improves the impression of relevant experiences
2014
Social Neuroscience
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test; t(9) = 16.47, p < .001). ...
Subjects rated greater willingness to cooperate with evaluators who had demonstrated active, compared to non-active, listening behavior (paired t test; t(17) = 6.10, p < .001). ...
doi:10.1080/17470919.2014.954732
pmid:25188354
pmcid:PMC4270393
fatcat:cctffwuzxbf4noft4nqlamwtvm
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