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Towards a Geriatrics Policy Integrated to the Primary Health Cares in Africa (The Case of Senegal)

Ka O, Leye MMM
2016 Journal of Gerontology & Geriatric Research  
Context and Justifications Upon the statistics and demographic data, the country of Senegal, as southern countries, will not escape from the aging process of its population which is currently young (60%  ...  The alternative is to integrate the medical particularity and specificity of the elders in to the global care system within the framework of Primary Health Cares.  ...  Hospital morbidity of high blood pressure in cardiology area increased from 14.6% in 1960, to 22.6% in 1970, to 42.6% in 1991 [5] .  ... 
doi:10.4172/2167-7182.1000274 fatcat:wqun4lil65bojmd6b2c62owwxa

Arterial pulse wave velocity in coronary arteries

J. Aguado-Sierra, K.H. Parker, J.E. Davies, D. Francis, A.D. Hughes, J. Mayet
2006 IEEE Engineering in Medicine and Biology Society. Conference Proceedings  
Pulse wave velocity changes with age and disease and is a useful indicator of cardiovascular disease.  ...  Characteristic impedance calculations show the greatest variation of all methods. The Σ 2 method was further assessed in vitro for use in coronary vessels.  ...  The PU-loop method relies upon the identification of a linear portion of the pressure-velocity curve when only forward waves are present [7] ; its slope is equal to ρc (where ρ is the density of blood  ... 
doi:10.1109/iembs.2006.4397539 fatcat:2hv36wmgojeotdkodptqixinfy

Arterial pulse wave velocity in coronary arteries

J. Aguado-Sierra, K.H. Parker, J.E. Davies, D. Francis, A.D. Hughes, J. Mayet
2006 2006 International Conference of the IEEE Engineering in Medicine and Biology Society  
Pulse wave velocity changes with age and disease and is a useful indicator of cardiovascular disease.  ...  Characteristic impedance calculations show the greatest variation of all methods. The Σ 2 method was further assessed in vitro for use in coronary vessels.  ...  The PU-loop method relies upon the identification of a linear portion of the pressure-velocity curve when only forward waves are present [7] ; its slope is equal to ρc (where ρ is the density of blood  ... 
doi:10.1109/iembs.2006.259375 pmid:17946867 fatcat:ehtmwyo5qnb5rgkyqube3hg56y

Hyperelastic remodeling in the intrauterine growth restricted (IUGR) carotid artery in the near-term fetus

R. Blair Dodson, Paul J. Rozance, Esther Reina-Romo, Virginia L. Ferguson, Kendall S. Hunter
2013 Journal of Biomechanics  
Quantitative assessment of collagen fiber orientation in secondary harmonic generation images confirmed the shift in orientation between the two groups.  ...  IUGR is associated altered hemodynamics characterized by increased resistance to blood flow in the placenta and elevated fetal arterial pressure and pulsatility.  ...  This project was funding in part by the American Heart Association, Sigma Xi grants in aid, NIH grants: 1K08HD060688-1, 1K25HL094749-1, and 1R01DK088139-01A1, and Center for Women's Health Research, and  ... 
doi:10.1016/j.jbiomech.2012.12.013 pmid:23332229 pmcid:PMC3742322 fatcat:ps5uxuviqzgqjeqqbhrtd3wkvy

MECHANISMS IN ENDOCRINOLOGY: Are metabolically healthy obese individuals really healthy?

Matthias Blüher
2014 European Journal of Endocrinology  
In this review, the prevalence, potential biological mechanisms, and the clinical relevance of MHO are discussed.  ...  Obesity has become one of the major public health concerns of the past decades, because it is a key risk factor for type 2 diabetes, cardiovascular diseases, dyslipidemia, hypertension, and certain types  ...  Specifically, the definition of metabolic syndrome in obese included: elevated blood pressure, defined as i) systolic blood pressure R130 mmHg or diastolic blood pressure R85 mmHg, or antihypertensive  ... 
doi:10.1530/eje-14-0540 pmid:25012199 fatcat:liu4f4mhlra6bmsbes6xvhwir4

Lifestyle and environment [chapter]

2011 McDonald's Blood Flow in Arteries  
., Pomerance, A. et al. 1987: Human aging: changes in structure and function. Journal of the American College of Cardiology 10, 42A-7A.  ...  Clinical Science (London) 79(1), 73-9. Imholz, B.P., Parati, G., Manciam, G. et al. 1992 : Effects of graded vasoconstriction upon the measurement of finger arterial pressure.  ... 
doi:10.1201/b13568-34 fatcat:6crktq5cofbarf2lgel3j6ytiy

Origins, practices and future of safety pharmacology

Alan Bass, Lewis Kinter, Patricia Williams
2004 Journal of pharmacological and toxicological methods  
The origins of safety pharmacology are grounded upon observations that organ functions (like organ structures) can be toxicological targets in humans exposed to novel therapeutic agents, and that drug  ...  The criticality of identifying undesired adverse effects of new drugs in nonclinical models, which reflect the overall human condition, is reflected in the importance of generating an integrated and accurate  ...  The origins of safety pharmacology are grounded upon observations that organ functions (like organ structures) can be toxicological targets in humans exposed to novel therapeutic agents and that drug effects  ... 
doi:10.1016/j.vascn.2004.02.007 pmid:15172010 fatcat:2pdyukfmzjhh3h3kwiymefvt34

A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program [article]

Adrienne M Stilp, Leslie S Emery, Jai G Broome, Erin J Buth, Alyna T Khan, Cecelia A Laurie, Fei Fei Wang, Quenna Wong, Dongquan Chen, Catherine M D'Augustine, Nancy L Heard-Costa, Chancellor R Hohensee (+60 others)
2020 bioRxiv   pre-print
The harmonized phenotype data and associated documentation have been submitted to National Institutes of Health data repositories for controlled-access by the scientific community.  ...  Harmonization of the data usually requires substantial effort due to heterogeneity in phenotype definitions, study design, data collection procedures, and data set organization.  ...  The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Heart, Lung, and Blood Institute; the National Institutes of Health; or the U.S  ... 
doi:10.1101/2020.06.18.146423 fatcat:4yloxtpd4fcedirt3mewlt2v5m

HeartBioPortal2.0: new developments and updates for genetic ancestry and cardiometabolic quantitative traits in diverse human populations [article]

Bohdan B Khomtchouk, Kasra A Vand, Christopher S Nelson, Salvator Palmisano, Robert L Grossman
2020 bioRxiv   pre-print
across the continuous cardiometabolic spectrum from health (e.g., blood pressure traits) to disease (hypertension), facilitating the understanding of CVD trait genetics that inform health-to-disease transitions  ...  experience and provide a data commons that co-locates data, storage and computing infrastructure in the context of studying the genetic basis behind the leading cause of global mortality.  ...  blood pressure or some other trait.  ... 
doi:10.1101/2020.10.19.346445 fatcat:4xwafve2dngxfd4zrfimuwppla

Genome Database of the Latvian Population (LGDB): Design, Goals, and Primary Results

Vita Rovite, Yael Wolff-Sagi, Linda Zaharenko, Liene Nikitina-Zake, Elmars Grens, Janis Klovins
2018 Journal of Epidemiology  
The standard set of biosamples stored in the LGDB consists of DNA, plasma, serum, and white blood cells; in some cohorts, these samples are complemented by cancer biopsies and microbiome and urine samples  ...  Further challenges of the LGDB are the enrichment and harmonization of collected biosamples and data, the follow-up of selected participant groups, and continued networking and participation in collaboration  ...  ACKNOWLEDGEMENTS The Genome Database of the Latvian Population is supported by the Latvian Ministry of Health (Agreement No. 6-1396-2016).  ... 
doi:10.2188/jea.je20170079 pmid:29576601 pmcid:PMC6048300 fatcat:udnd2ziskrdi7fpprg4spnh3y4

The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents

Vincent W. V. Jaddoe, LifeCycle Project Group, Janine F. Felix, Anne-Marie Nybo Andersen, Marie-Aline Charles, Leda Chatzi, Eva Corpeleijn, Nina Donner, Ahmed Elhakeem, Johan G. Eriksson, Rachel Foong, Veit Grote (+24 others)
2020 European Journal of Epidemiology  
Early life is an important window of opportunity to improve health across the full lifecycle.  ...  Combining data will lead to the possibility of identifying smaller effect estimates, and the opportunity to better identify risk groups and risk factors leading to disease across the lifecycle across countries  ...  All study specific acknowledgements and funding are presented in the supplementary materials.  ... 
doi:10.1007/s10654-020-00662-z pmid:32705500 pmcid:PMC7387322 fatcat:wqmpvb2qdrg4xghjgdnit74nl4

Assessment of calvarial structure motion by MRI

William T Crow, Hollis H King, Rita M Patterson, Vincent Giuliano
2009 Osteopathic Medicine and Primary Care  
Practitioners of manual medicine/manual therapy (MM/MT) who utilize techniques thought to have some impact upon and move the solid structures of the human head have been criticized for lack of evidence  ...  structure motion in general.  ...  Support for research design and biostatistics was provided by The Osteopathic Research Center at the University of North Texas Health Science Center.  ... 
doi:10.1186/1750-4732-3-8 pmid:19732453 pmcid:PMC2743699 fatcat:6dcbxc3fxvcjxejalwogyn3e5e

Acute Effect of High-Intensity Interval Cycling on Carotid Arterial Stiffness and Hemodynamics

Wenxue Yuan, Haibin Liu, Zhilin Luan, Zhinan Zhao, Bingyi Shen
2019 BioMed Research International  
Therefore, understanding the alterations of human carotid arterial stiffness and hemodynamics is of great clinical value in the prevention and treatment of CVD. Objective.  ...  In this study, we aimed to investigate the acute effect of high-intensity interval cycling (HIIC) on carotid arterial stiffness and hemodynamics in sedentary. Methods.  ...  Acknowledgments e authors extend their gratitude to all the subjects who participated in this study. is work was funded by the National Natural Science Foundation of China (81601174) and the Fundamental  ... 
doi:10.1155/2019/6260286 pmid:31998773 pmcid:PMC6970504 fatcat:geqllbckcfcadkl2scly6zv4qa

Near 10-Year and Longer Periods Modulate Circadians: Intersecting Anti-aging and Chronoastrobiological Research

F. Halberg, G. Cornelissen, Y. Watanabe, K. Otsuka, B. Fiser, J. Siegelova, V. Mazankova, C. Maggioni, R. B. Sothern, G. S. Katinas, E. V. Syutkina, N. Burioka (+1 others)
2001 The journals of gerontology. Series A, Biological sciences and medical sciences  
There are about 50-year (circasemicentennian) cycles in mortality from stroke in Minnesota and in the Czech Republic and also in human morphology at birth, the latter result reducing the likelihood that  ...  Associations accumulate between cycles of natural physical time structures, chronomes such as the 10.5-year (circadecennian) Schwabe and the 21-year (circavigintunennian) Hale cycles of solar activity,  ...  Public Health Service (GM-13981); National Heart, Lung, and Blood Institute, National Institutes of Health (HL-40650); University of Minnesota Supercomputer Institute, Dr. h.c. Dr. h.c.  ... 
doi:10.1093/gerona/56.5.m304 pmid:11341244 fatcat:e7htg3s7obhlbnamfnczviax7i

Harmonizing Biomarker Measurements in Longitudinal Studies of Children's Health and the Environment

Ruth Etzel, Marie-Aline Charles, Michael Dellarco, Katie Gajeski, Karl-Heinz Jöckel, Steven Hirschfeld, Michihiro Kamijima, Toshihiro Kawamoto, Marike Kolossa-Gehring, Shoji Nakayama, Börge Schmidt, Ying Tian (+3 others)
2014 Biomonitoring  
AbstractLarge scale studies of environmental influences on children's health and development are being planned or conducted in many places, including Japan, France, Shanghai (China), the United States,  ...  Harmonization of infant health outcomes, biomarkers, environmental measurements, socioeconomic and migration status has been initiated.  ...  First, it has drawn the attention of policymakers in these 5 countries to the importance of understanding the effect of exposures to environmental contaminants on the health and development of children  ... 
doi:10.2478/bimo-2014-0006 fatcat:635tozhagnflpkrkxkuacqu2ym
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