A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
Filters
Controlling Ligand Binding in Myoglobin by Mutagenesis
2001
Journal of Biological Chemistry
Preserved Fulltext
A quadruple mutant of sperm whale myoglobin was constructed to mimic the structure found in Ascaris suum hemoglobin. The replacements include His(E7) 3 Gln, Leu(B10) 3 Tyr, Thr(E10) 3 Arg, and Ile(G8) 3 Phe. Single, double, and triple mutants were characterized to dissect out the effects of the individual substitutions. The crystal structures of the deoxy and oxy forms of the quadruple mutant were determined and compared with that of native Ascaris hemoglobin. Tyr(B10) myoglobin displays low O
doi:10.1074/jbc.m109206200
pmid:11744723
fatcat:lfvfqklqlndc5ddvu3cmqqmrr4
more »
... affinity, high dissociation rate constants, and heterogeneous kinetic behavior, suggesting unfavorable steric interactions between the B10 phenol side chain and His(E7). In contrast, all mutants containing the Tyr(B10)/Gln(E7) pair show high O 2 affinity, low dissociation rate constants, and simple, monophasic kinetic behavior. Replacement of Ile 107 with Phe enhances nanosecond geminate recombination singly and in combination with the Tyr(B10)/Gln(E7)/Arg(E10) mutation by limiting access to the Xe4 site. These kinetic results and comparisons with native Ascaris hemoglobin demonstrate the importance of distal pocket cavities in governing the kinetics of ligand binding. The ϳ150-fold higher O 2 affinity of Ascaris hemoglobin compared with that for Tyr(B10)/Gln(E7)-containing myoglobin mutants appears to be the result of favorable proximal effects in the Ascaris protein, due to a staggered orientation of His(F8), the lack of a hydrogen bonding lattice between the F4, F7, and F8 residues, and the presence of a large polar Trp(G5) residue in the interior portion of the proximal heme pocket. More than 50 years ago, Davenport (1) showed that the ultrahigh affinity of Ascaris suum hemoglobin for O 2 is due to a remarkably small rate constant for O 2 dissociation (Յ0.01 s Ϫ1 ). In 1994, De Baere et al. (2) and Kloek et al. (3) suggested that the structural cause of the low dissociation rate was electrostatic stabilization of bound O 2 by two hydrogen bonds, a very strong one with Tyr(B10) and a weaker one with Gln(E7).
The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding
[article]
2021
bioRxiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
Recent evidence indicated that HIV-1 Integrase (IN) binds genomic viral RNA (gRNA) playing a critical role in viral particle morphogenesis and gRNA stability in host cells. Combining biophysical and biochemical approaches we show that the C-terminal flexible 18-residues tail of IN acts as a sensor of the peculiar apical structure of trans-activation response element RNA (TAR), directly interacting with its hexaloop. We highlighted how the whole IN C-terminal domain, once bound to TAR, can
doi:10.1101/2021.10.21.465253
fatcat:uhxbnch7m5aipnyyg7aikipki4
more »
... its structure assisting the binding of Tat, the HIV trans-activator protein, which finally displaces IN from TAR. Our results are consistent with the emerging role of IN in early stage of proviral transcription and suggest new steps of HIV-1 life cycle that can be considered as therapeutic targets.
Acknowledgement to Reviewers of Foods in 2019
2020
Foods
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Josep
Merlino, Valentina Maria
Mesnage, Robin
Mhd Jalil, Abbe Maleyki
Miao, Tianxin
Miceli, Natalizia
Micevski, Milena
Michalska, Anna
Michel, Frederick
Michel, Maximilian
Middendorf, Dana
Miele ...
Noordergraaf, Inge-Willem
Nowak, Adriana
Nowak, Agnieszka
Nowak, Anna
Nowak, Dorota
Nunes, Cecilia
Núñez Carmona, Estefanía
Nunez, Oscar
Nychas, George-John E.
O'Keefe, Sean F. ...
doi:10.3390/foods9010107
fatcat:tdffddaeijfwzp6uk3q5s5tsai
Page 10879 of Psychological Abstracts Vol. 90, Issue 4
[page]
2003
Psychological Abstracts
Preserved Fulltext
The Internet Archive has digitized a microfilm copy of this work. It may be possible to borrow a copy for reading.
., 10465 McDowell, Christopher, 9615 McEachern, Adriana G., 10289 McElroy, Todd, 9765 McEvoy, Joseph P., 8847 McFarland, Christine, 10376 McFarlane, Alexander, 10228 McGarigle, Carol, 11073 McGee, Anna ...
Mimi, 9597
XXXVil
Miassy-Maljak, Nelly, 11433 Michaelis, Benjamin H., 10135 Michalak, Erin E., 10136 Michalski, Joseph H., 11185 Michelson, David, 10964, 10984 Mick, Eric, 10029
Midford, Richard, 11464 Miele ...
Acknowledgement to Reviewers of Cells in 2018
2019
Cells
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Michiels, Carine Mielcarek, Michal Miele, Adriana Erica Milavetz, Barry Miletta, Maria Millar, J. Cameron Miller, Robert H. ...
doi:10.3390/cells8010060
fatcat:uplolcg53rappa4peqn6umjkg4
Acknowledgement to Reviewers of Microorganismsin 2019
2020
Microorganisms
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Midelet-Bourdin, Graziella
Miele, Adriana E.
Mierzejewska, Jolanta
Mihai, Mara
Mihalca, Andrei Daniel
Milhano Santos, Fátima
MILLEMANN, Yves
Miller, Darlene
Miller, Joanna L. ...
Valiadi, Martha
Valitutti, Francesco
Vallance, Bruce
Vallesi, Adriana
Vallini, Giovanni
Valls,
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. ...
doi:10.3390/microorganisms8020155
fatcat:mgitenfq2ffn5djbcdlgagk654
Acknowledgement to Reviewers of Crystals in 2019
2020
Crystals
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Miele, Adriana Erica Mihai, Marcela Mikuśkiewicz, Marta Milanesio, Marco Milanova, Maria Mildren, Rich Milioto, Stefana Miller, Wolfram Miller, Reece G. ...
Bialecka-Florjańczyk, Ewa Bigi, Adriana Bigourd, Damien Bikbaev, Rashid G. Bilal, Osama R. ...
doi:10.3390/cryst10010045
fatcat:xrqxe6asejahrdj2qyy55dagee
UNIVERSIDAD DE LOS ANDES
2006
unpublished
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
Patricia Vit, Eunice Enriquez, Monika O Barth, Adriana H Matsuda, Ligia B. ...
Para las abejas nativas de Venezuela, el concepto miel de panal se transforma en miel de botija. Su uso como alimento y medicamento data desde los Mayas. ...
fatcat:hqak6szin5hhdk6zu4psc6jgti
Supplemental Material for Proceedings of the American Psychological Association, Incorporated, for the Legislative Year 2015: Minutes of the Annual Meeting of the Council of Representatives February 20–22, 2015, Washington, DC, and August 5 and August 7, 2015, Washington, DC, and Minutes of the February, June, August, and December 2015 Meetings of the Board of Directors
2016
American Psychologist
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
Rosen, Jennifer Eve
Rosenthal, Erica K.
Ross, Cindy M. ...
Michel, Cammy Anne
Michel, Lorena
Mickelson, Bryan
Mickolus, Ciana
Miele, David
Miers, Erin Michelle
Mikell, Christie
Milano, Matthew J.
Milhem, Erin C. ...
doi:10.1037/amp0000022.supp
fatcat:eqfef43wi5b4lfjrylvttjxqo4
Acknowledgment to Reviewers of Foods in 2020
2021
Foods
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Tropea Garzia, Giovanna Maria Daniela
Tirelli, Antonio
Trudo, Sabrina
Tirloni, Erica
Trujillo, Trystram, Gilles
Todolí, José Luis
Trzaskowska, Monika
Toepel, Ulrike
Tsafantakis, Nikolaos
Tofalo ...
Izabela
Molin, Marianne
Michalska, Anna
Monaci, Linda
Michel, Piotr
Monago-Maraña, Olga
Michel, Visalli
Moniruzzaman, Mohammed
Middendorf, Dana
Monks, Jenifer
Midmore, David
Montaña, María
Miele ...
doi:10.3390/foods10020238
pmid:33503802
fatcat:g6m3e4uitbaqnklbsl6kyqhsta
Acknowledgment to Reviewers of Microorganisms in 2020
2021
Microorganisms
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Miele, Adriana E.
McFeeters, Robert
Mierzejewska, Jolanta
McGill, Jodi
Migheli, Quirico
McGiven, John
Miglietta, Maria
Mcgregor, Neil
Miglio, Arianna
McInroy, John A. ...
Valitutti, Francesco
Verma, Ranjit
Vallesi, Adriana
Verma, Smriti
Valm, Alex M. ...
doi:10.3390/microorganisms9020268
pmid:33525504
fatcat:hp6zrmsihfhtvaffyrbvr5wcze
Acknowledgment to Reviewers of Animals in 2020
2021
Animals
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Feuerbacher, Erica
Farouk, Mohammed Hamdy
Feyera, Takele
Farzan, Vahab
Fidalgo, Miguel
Fassani, Édison José
Figueroa Millán, Julio V. ...
Sakhawat
Huo, Lijun
Hostens, Miel
Hussain, Hidayat
Jewgenow, Katarina Laven, Richard
Laarman, Anne
Lavon, Yaniv
Labroussaa, Fabien
Lavrenčič, Andrej
Lacham-Kaplan, Orly
Lawrence, Catherine E. ...
doi:10.3390/ani11020313
pmid:33513681
fatcat:asbkefrlszfw3bvbvk74ccxkmy
Apuntes para la vida de Alfredo González Prada
1946
Letras : Órgano de la Facultad de Letras y Ciencias Humanas
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Doña Adriana estaba en París. ...
La Junta se hallaba en plena luna de miel con la Democracia y su hermana, la Libertad. El lenguaje de los discursos oficiales habría sido maratiano si no hubiese olido va a restauración. ...
Esto es como la boca de Vemis, que decía Luciano: dientes capaces de morder pero miel bajo la lengua. No es posible vivir bajo la férula de los generales v doctores sudamericanos". ...
doi:10.30920/letras.12.33.1
fatcat:3agdvtbskbdk5jabcepyvo35yu
Acknowledgment to Reviewers of Nutrients in 2020
2021
Nutrients
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Sosa, Erica
Staal, Jens
Sotek, Zofia
Stabouli, Stella V.
Soto, Esther Cuadrado
Stachowska, Ewa
Sotomayor, Camilo G. ...
, Silvia
Merkler, David
Miguez, Patricia
Merli, Manuela
Mika, Adriana
Merlino, Valentina Maria
Mikhailov, Theresa A. ...
doi:10.3390/nu13020382
fatcat:dsp57pmq2bbmpic7mxscti4qoa
Acknowledgement to Reviewers of Nutrients in 2019
2020
Nutrients
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Micillo, Raffaella Micke, Oliver Miele, Luca Miele, Mara Mielenz, Manfred Mielgo, Juan Mielgo-Ayuso, Juan Mierzyński, Radzisław Míguez, Jesús M. ...
Uddin, Golam Mezbah
Uebanso, Takashi
Ueda, Norishi
Uehara, Mariko
Ufnal, Marcin
Ulatowski, Lynn
Ullrich, Matthias
Ullrich, Reiner
Ulrich, Craig
Umar, Shahid
Ummarino, Simone
Unger, Erica ...
doi:10.3390/nu12010273
fatcat:hc5qsecoqzhl3l3aa2eyhhljpq
« Previous
Showing results 1 — 15 out of 46 results