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Video-rate fluorescence lifetime imaging camera with CMOS single-photon avalanche diode arrays and high-speed imaging algorithm

David D.-U. Li, Jochen Arlt, David Tyndall, Richard Walker, Justin Richardson, David Stoppa, Edoardo Charbon, Robert K. Henderson
2011 Journal of Biomedical Optics  
To demonstrate its performance, a widefield microscope was adapted to accommodate the SPAD array and image different test samples.  ...  A high-speed and hardware-only algorithm using a center of mass method has been proposed for singledetector fluorescence lifetime sensing applications.  ...  The CMOS SPAD chip has been supported by the European Commission within the 6th Framework Programme of the Information Science Technologies, Future Emerging Technologies Open MEGAFRAME project (Contract  ... 
doi:10.1117/1.3625288 pmid:21950926 fatcat:ypgc4fmduzcu7cmlixjunlq5xy

Microarchitecture of a MultiCore SoC for Data Analysis of a Lab-on-Chip Microarray

G. Kornaros, S. Blionas
2008 EURASIP Journal on Advances in Signal Processing  
The proposed architecture employs reconfigurable technology and has the capacity to process data from microarrays of various sizes from small size ones used in genotyping up to large-scale gene expression  ...  for microarray real-time data processing and for a scalable reconfigurable architecture to handle also the future highdensity microarrays.  ...  Lorne Lonie, Marta Paolucci, and Dr.  ... 
doi:10.1155/2008/520641 fatcat:aou4oavdkbgajp56mwrlzl6ceu

New and Interesting at PITTCON 2005

2005 Microscopy Today  
digital image acquisition: the Universal Spectral Engine (USE).  ...  Ideal for HCS (High Content Screening), Cellular Imaging, Microarray Imaging, Hyperspectral Imaging, Fluorescence/Chemiluminescence Detection and Confocal Microscopy.  ... 
doi:10.1017/s1551929500051683 fatcat:pntbmv4k4ffrpdkiqvzpqplvpu

Silicon-based Integrated Microarray Biochips for Biosensing and Biodetection Applications [chapter]

Lei Zhang, Cheng Zhu, Jinwen Geng, Xizeng Shi, Yunhua Gao, Zhijie Chang, He Qian
2015 Biosensors - Micro and Nanoscale Applications  
silicon-based complementary metal-oxidesemiconductor (CMOS) technology, multi-target detection capabilities, signal processing and system integrations, etc.  ...  In this way, we discuss future siliconbased fully integrated biochips, which could be used for portable medical detection and low cost PoC diagnosis applications.  ...  Acknowledgements The authors would like to thank the support of the National Natural Science Foundation of China under grant 61101001 and Tsinghua University Initiative Scientific Research Programme.  ... 
doi:10.5772/60441 fatcat:qf6d2as3bjd5xb2ueegaqp3dx4

Field Programmable Gate Array Applications—A Scientometric Review

Juan Ruiz-Rosero, Gustavo Ramirez-Gonzalez, Rahul Khanna
2019 Computation  
, image and video processing, big data, computer algorithms and other applications.  ...  These publications show the vast range of applications based on FPGAs, from the new mechanism that enables the magnetic suspension system for the kilogram redefinition, to the Mars rovers' navigation systems  ...  Research on the High-Speed Image Acquisition and Storage Technology based on TMS320C6748.  ... 
doi:10.3390/computation7040063 fatcat:wxtatzsvvnfopghdfl25hcfc2a

Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony

Alexandre T. Vessoni, Roberto H. Herai, Jerome V. Karpiak, Angelica M. S. Leal, Cleber A. Trujillo, Annabel Quinet, Lucymara F. Agnez Lima, Carlos F. M. Menck, Alysson R. Muotri
2016 Human Molecular Genetics  
using unbiased RNA-seq gene expression analyses.  ...  Classical symptoms of CS patients include failure to thrive and a severe neuropathology characterized by microcephaly, hypomyelination, calcification and neuronal loss.  ...  Acknowledgements Authors want to thank Cassiano Carromeu and Brian Lee for helping with cell reprogramming and neuronal differentiation.  ... 
doi:10.1093/hmg/ddw008 pmid:26755826 pmcid:PMC4787902 fatcat:4hrwm2pqbvbshd6qnrbl5hergq

Single-photon avalanche diode imagers in biophotonics: review and outlook

Claudio Bruschini, Harald Homulle, Ivan Michel Antolovic, Samuel Burri, Edoardo Charbon
2019 Light: Science & Applications  
, time-stamping and processing capabilities.  ...  Single-photon avalanche diode (SPAD) arrays are solid-state detectors that offer imaging capabilities at the level of individual photons, with unparalleled photon counting and time-resolved performance  ...  The authors would like to thank Scott Lindner and Arin Can Ulku (EPFL AQUA) for their kind assistance.  ... 
doi:10.1038/s41377-019-0191-5 pmid:31645931 pmcid:PMC6804596 fatcat:bszl5iwf5zae7p7223565wjpsi

Author Correction: Single-photon avalanche diode imagers in biophotonics: review and outlook

Claudio Bruschini, Harald Homulle, Ivan Michel Antolovic, Samuel Burri, Edoardo Charbon
2020 Light: Science & Applications  
The authors would like to thank Scott Lindner and Arin Can Ulku (EPFL AQUA) for their kind assistance. Conflict of interest The authors declare that they have no conflict of interest.  ...  An FPGA system indeed offers some flexibility in terms of possible data processing and a high computational bandwidth, which can be used, for example, to realise firmware-based 32 × 32 autocorrelator arrays  ...  acquisition are hard to scale to large multichannel arrays; scanning is, therefore, required when TSCPC is used in an imaging setup.  ... 
doi:10.1038/s41377-020-0248-5 pmid:32025295 pmcid:PMC6987173 fatcat:3wjkeuxwhfbxbiykg34m3qzg64

Trends in Machine Learning for Signal Processing [In the Spotlight]

Tulay Adali, David Miller, Konstantinos Diamantaras, Jan Larsen
2011 IEEE Signal Processing Magazine  
system generator of Xilinx. Many FPGA chips also contain embedded processors rendering them complete platforms for DSP system design.  ...  The contribution of SP to the acquisition and analysis of these data was crucial since biomolecular signals-e.g., microarray-based gene expression profiles, protein spots in gels, mass spectra, biomolecular  ... 
doi:10.1109/msp.2011.942319 fatcat:brwvz3sjvrfyboqvieovxvfrd4

Single-photon SPAD imagers in biophotonics: Review and Outlook [article]

Claudio Bruschini, Harald Homulle, Ivan Michel Antolovic, Samuel Burri, Edoardo Charbon
2019 arXiv   pre-print
and processing capabilities.  ...  Single-photon avalanche diode (SPAD) arrays are solid-state detectors offering imaging capabilities at the level of individual photons, with unparalleled photon counting and time-resolved performance.  ...  An FPGA system indeed offers some flexibility in terms of possible data processing and high computational bandwidth, which can be used for example to realize firmware-based 32×32 autocorrelator arrays  ... 
arXiv:1903.07351v1 fatcat:fyseairjsfbn5fb77omgoxnqma

An Outlook on Design Technologies for Future Integrated Systems

G. De Micheli
2009 IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems  
paving the way to a new class of heterogeneous integrated systems, with increased performance and connectedness and providing us with gateways to the living world.  ...  This paper surveys design requirements and solutions for heterogeneous systems and addresses design technologies for realizing them.  ...  In these studies, a set of clinical traits were manually extracted from medical images and then correlated to the data extracted from microarrays.  ... 
doi:10.1109/tcad.2009.2021008 fatcat:2qujxzmnjbfebd4fg3bnrzsjua

Table of Contents

2018 2018 International Conference on Advances in Computing, Communications and Informatics (ICACCI)  
) 1207 Development of Data Acquisition System using non-invasive Hardware and 3D software for Electric all terrain Vehicle Saroja Siddamal (KLE Technological University, India), Akshaykumar Sunagar  ...  Tracking by Multi-Agent in Octagonal Formation using Conventional and Adaptive Control B.  ... 
doi:10.1109/icacci.2018.8554765 fatcat:w77tqf7bjzda5dyztz46rh5eke

Human Body-Related Disease Diagnosis Systems Using CMOS Image Sensors: A Systematic Review

Suparshya Babu Sukhavasi, Susrutha Babu Sukhavasi, Khaled Elleithy, Shakour Abuzneid, Abdelrahman Elleithy
2021 Sensors  
CMOS image sensor (CIS) became a prominent technology in assisting the monitoring and clinical diagnosis devices to treat diseases in the medical domain.  ...  The corresponding CIS models used in systems are mapped organ-wise, and the data collected over the last decade are tabulated.  ...  The Iris detection algorithm's traditional process involves image acquisition, Iris image enhancement, binarization, and recognition.  ... 
doi:10.3390/s21062098 pmid:33802718 pmcid:PMC8002412 fatcat:bkzvivl3zjhobikwgxcn55iuca

Edge Detection in Satellite Image Using Cellular Neural Network

Osama Basil, Dr. Mohamed, Dr. Hala
2014 International Journal of Advanced Computer Science and Applications  
CNN based edge detector in used conjunction with image enhancement and noise removal techniques, in order to deliver accurate edge detection results, compared with state of the art approaches.  ...  The proposed image processing chain deliver more details regarding edges than canny edge detector.  ...  Due to the fact that the image processing system is easy to use, it can be applied in various image processing applications.  ... 
doi:10.14569/ijacsa.2014.051010 fatcat:c5htb7bqwfcaxnscfkzp62bwey

Synobins: An Intermediate Level towards Annotation and Semantic Retrieval

Daniela Stan Raicu, Ishwar K. Sethi
2006 EURASIP Journal on Advances in Signal Processing  
A system developed using our proposed feature model will have the capability of learning associations not only between semantic concepts and images, but also between semantic concepts and patterns.  ...  We evaluated the performance of our system based on the retrieval accuracy and on the perceptual similarity order among retrieved images.  ...  Prospective authors should submit an electronic copy of their complete manuscript through the EURASIP JASP manuscript tracking system at http://www.mstracking.com/asp/, according to the following timetable  ... 
doi:10.1155/asp/2006/63124 fatcat:k6t4kntr5fcivgnr2lrhor7cum
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