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Accelerating Experimental Design by Incorporating Experimenter Hunches [article]

Cheng Li, Santu Rana, Sunil Gupta, Vu Nguyen, Svetha Venkatesh, Alessandra Sutti, David Rubin, Teo Slezak, Murray Height, Mazher Mohammed, Ian Gibson
2019 arXiv   pre-print
Experimental design is a process of obtaining a product with target property via experimentation.  ...  Often, expert experimenters have 'hunches' about the behavior of the experimental system, offering potentials to further improve the efficiency.  ...  CONCLUSION We have proposed a Bayesian optimization algorithm to incorporate the hunches experimenters possess about the change of experimental results with respect to certain variables to accelerate experimental  ... 
arXiv:1907.09065v1 fatcat:j6iuddrq4rdnhoorjc6sb5wzkm

Page 469 of Contemporary Psychology Vol. 27, Issue 6 [page]

1982 Contemporary Psychology  
This text presents the scientific enterprise as a heuristic pro- cess fraught with numerous decisions and problem points that are as often resolved by hunches and values as by objective criteria (which  ...  The methods text written by Ray and Ravizza uses a different approach to teach experimental psychology.  ... 

LTRACK—Beam-transport calculation including wakefield effects

K. C. D. Chan, R. K. Cooper
1988 AIP Conference Proceedings  
\round 1984, Bane adapted LTR.4CK for use in investigating the effectiveness I+ Landau darnping for curing single bunch beam breakup caused by the dipc,le wakefield in the SLC.5 Cumently we have incorporated  ...  Sec~ndly, while people try to design accelerators with hifih pmk c~wrmlts and demand good beam qualities, they need codes of this kind to trt=nt wnkrfield effects properly, There are two import~?  ... 
doi:10.1063/1.37810 fatcat:s57e6cq4nfaxhj33zzol2mav3i

Summary Report of Working Group 6: Laser-Plasma Acceleration

Wim Leemans, Michael Downer, Craig Siders
2006 AIP Conference Proceedings  
In large part because of Dave's efforts over the years, support for this work was provided by the US. Department of Energy.  ...  ACKNOWLEDGMENTS We thank the Workshop organizers and all of the participants in the Laser-Plasma Acceleration Working Group.  ...  Downer), injection of electrons into laser-plasma accelerators (led by W. Leemans), simulations vs. experimental diagnostics (led by M. Downer), scaling laws for laser-plasma accelerators (led by C.  ... 
doi:10.1063/1.2409132 fatcat:oan2tpblnrexbf37wnejqhfbwu

Incorporating Expert Prior Knowledge into Experimental Design via Posterior Sampling [article]

Cheng Li, Sunil Gupta, Santu Rana, Vu Nguyen, Antonio Robles-Kelly, Svetha Venkatesh
2020 arXiv   pre-print
Experimenters can often acquire the knowledge about the location of the global optimum. However, they do not know how to exploit this knowledge to accelerate experimental design.  ...  Experimental design is therefore involved with the task of finding the optimal experimental input that results in the desirable output by using as few experiments as possible.  ...  The experimental results were discussed by all authors.  ... 
arXiv:2002.11256v1 fatcat:lcp7quchn5g6hb2jb5jva3kwea

Response Modification Factor of RC Frames Strengthened with RC Haunches

Junaid Akbar, Naveed Ahmad, Muhammad Rizwan, Sairash Javed, Bashir Alam
2020 Shock and Vibration  
The design philosophy of the retrofit solution is to allow beam-column members to deform inelastically and dissipate seismic energy.  ...  Shake table tests were performed on three 1 : 3 reduced scale two-story RC frame models, including one model incorporating construction deficiencies common in developing countries, which was retrofitted  ...  By definition, R factor of a structure is the reduction required for reducing elastic base shear force of a structure used for seismic design of structures: Response Modification Factor Based on Experimental  ... 
doi:10.1155/2020/3835015 fatcat:mhtpyhtk4bcjnm2p2i76kz3wpu

Do I Have To Take Experimental Psychology?

Claire E. Weinstein
1982 Contemporary Psychology  
This text presents the scientific enterprise as a heuristic pro- cess fraught with numerous decisions and problem points that are as often resolved by hunches and values as by objective criteria (which  ...  The methods text written by Ray and Ravizza uses a different approach to teach experimental psychology.  ... 
doi:10.1037/021240 fatcat:scdkcsudlngu7gek66uhv2lpbu

Selected Problems of Children: An Interdisciplinary Forum

Alan E. Kazdin
1982 Contemporary Psychology  
This text presents the scientific enterprise as a heuristic pro- cess fraught with numerous decisions and problem points that are as often resolved by hunches and values as by objective criteria (which  ...  The methods text written by Ray and Ravizza uses a different approach to teach experimental psychology.  ... 
doi:10.1037/021239 fatcat:tjkfvfqp5ngg5lfvpwuypo57q4

Progress in Fusion Research

1978 Nature  
Cottrell's crucial hunch has been followed up in the intervening years by a large body of experiment and theory.  ...  The new tokamak TFTR at present under construction at Princeton is designed to achieve Q > 1 through the reduction in diffusive losses by the use of larger dimensions.  ... 
doi:10.1038/275175a0 fatcat:x3tgkht3crbw7bupzmle7w23gu

Application of Accelerometer to Monitor Students' Exercise Load in 50 m Round Trip

Hao Li, Meng Xu, Rahim Khan
2022 Computational Intelligence and Neuroscience  
This article proposes a human body motion recognition mechanism based on acceleration sensors by looking at the three trademark upsides, the wavefront edge, wavefront limit, and time stretch between the  ...  pinnacle and valley of the speed increase sensor vertical information waveform, and joining the rule of choice tree order to accomplish the activities of hunching down, taking off, and running.  ...  For example, the pedometer designed by an acceleration sensor can e ectively record the walking steps and distance of the human body and calculate the energy consumption of the human body in a period of  ... 
doi:10.1155/2022/3142677 pmid:35814553 pmcid:PMC9259259 fatcat:hahebapqhnf2jgi3z7onzmjvc4

In Leon's company, it seemed that anything might be possible [article]

Chris Quigg
2022 arXiv   pre-print
Leon wanted to build up experimental groups to participate in research at Fermilab and other accelerator laboratories.  ...  Leon again trusted his hunch but verified.  ... 
arXiv:2001.01879v2 fatcat:mpdadbyzsvhqpoakcdgnklspri

In vivo comparison of jellyfish and bovine collagen sponges as prototype medical devices

Jonathan P. Widdowson, Alex J. Picton, Valerie Vince, Chris J. Wright, Andrew Mearns-Spragg
2017 Journal of Biomedical Materials Research. Part B - Applied biomaterials  
ACKNOWLEDGMENTS The work carried out in this manuscript was partially funded by Innovate UK (project number 710665), who had no involvement in study design, data collection, analysis or interpretation,  ...  On declaration of interest, JPW, AJP, and AMS are employed by Jellagen Pty Ltd which produces collagen extracted from jellyfish.  ...  Each criterion was scored by a qualified histopathologist, blind to the experimental design, using a semiquantitative scoring system on a five-point scale: (0) absence, (1) slight, (2) moderate, (3) marked  ... 
doi:10.1002/jbm.b.33959 pmid:28741862 pmcid:PMC5947132 fatcat:lo76fk5povay5kuki6skrhco2e

Cellular and humoral immune responses to heat shock protein 65 are both involved in promoting fatty-streak formation in LDL-receptor deficient mice

Jacob George, Arnon Afek, Boris Gilburd, Yehuda Shoenfeld, Dror Harats
2001 Journal of the American College of Cardiology  
OBJECTIVES This study was designed to determine the role of cellular and humoral immune responses to heat shock protein 65 (HSP65) in murine atherosclerosis.  ...  Study design. EXPERIMENT 1.  ...  Proliferation was measured by the incorporation of [ 3 H] thymidine into deoxyribonucleic acid during the final 12 h of incubation.  ... 
doi:10.1016/s0735-1097(01)01440-1 pmid:11527651 fatcat:mnhwbx6z5vay5jrtapb3camlbu

Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice

Krista J. Spiller, Clark R. Restrepo, Tahiyana Khan, Anna M. Stieber, Linda K. Kwong, John Q. Trojanowski, Virginia M.-Y. Lee
2016 Acta Neuropathologica Communications  
progression was accelerated.  ...  We believe that these studies will be an important basis for the future design and evaluation of therapies designed to slow denervation and promote re-innervation in adult ALS patients.  ...  Acknowledgments This work was supported by The Brody Family Medical Trust Fellowship (K.J.S.) and NIA/NIH AG17586 (VMYL).  ... 
doi:10.1186/s40478-016-0377-5 pmid:27687289 pmcid:PMC5043606 fatcat:tkq2rintbfbbdad6sq7xotwzze

Preclinical Studies of MSC-Derived Extracellular Vesicles to Treat or Prevent Graft Versus Host Disease: a Systematic Review of the Literature

Manika Gupta, Alvin Tieu, Mitchell Slobodian, Risa Shorr, Dylan Burger, Manoj M Lalu, David S Allan
2020 Stem Cell Reviews and Reports  
The use of mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) appears promising and a systematic review of preclinical studies is needed to accelerate the design of translational studies  ...  Study design and outcome data were extracted and reporting was evaluated using the SYRCLE tool to identify potential bias.  ...  The baseline GVHD score incorporates characteristics such as skin integrity, body weight, hunch and fur texture and was not statistically different between the intervention groups in the 3 studies using  ... 
doi:10.1007/s12015-020-10058-x pmid:33159616 pmcid:PMC7648545 fatcat:iog4fqkp3rcepp5ib73zcigiva
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