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About the Lifespan of Peer to Peer Networks [article]

R. Cilibrasi, A. Navarra (LaBRI - Univ. Bordeaux 1), S. Perennes, P. Vitanyi (CWI/Univ. Amsterdam)
2006 arXiv   pre-print
We analyze the ability of peer to peer networks to deliver a complete file among the peers.  ...  According to this view the network has two main states: first centralized - few sources (roots) hold the complete file, and next distributed - peers hold some parts (chunks) of the file such that the entire  ...  that download files from the network but do not share their own chunks.  ... 
arXiv:cs/0612043v1 fatcat:7wmmxjzhcncj7jsjzgicjvpdp4

About the Lifespan of Peer to Peer Networks [chapter]

Rudi Cilibrasi, Zvi Lotker, Alfredo Navarra, Stephane Perennes, Paul Vitanyi
2006 Lecture Notes in Computer Science  
In this paper we analyze the ability of peer to peer networks to deliver a complete file among the peers.  ...  This surprisingly suggests that peer to peer networks are able to sustain only a limited amount of information.  ...  that download files from the network but do not share their own chunks.  ... 
doi:10.1007/11945529_21 fatcat:hyoejubynbbxpbr6kgvtcilyzi

Performance evaluation of Xunlei peer-to-peer network: A measurement study

Yong Zhao, Zhibin Zhang, Yipeng Wang, Li Guo, Binxing Fang
2011 2011 IEEE Consumer Communications and Networking Conference (CCNC)  
To evaluate the effects of above solutions, we perform a series of measurements on Xunlei and BitTorrent networks.  ...  of active peers but also the seed ratio.  ...  Therefore, the average downloading speed is close to the limit of downloading bandwidth. V. LIFESPAN The lifespan is another aspect of P2P network performance.  ... 
doi:10.1109/ccnc.2011.5766468 dblp:conf/ccnc/ZhaoZWGF11 fatcat:4jsa5ubjovezdbraciv54ttyuu

Designing Less-Structured P2P Systems for the Expected High Churn

F.E. Bustamante, Y. Qiao
2008 IEEE/ACM Transactions on Networking  
We address the problem of highly transient populations in unstructured and loosely-structured peer-to-peer systems.  ...  While merely illustrative, the evaluated strategies and protocols clearly demonstrate the advantages of considering peers' session time in designing widely-deployed peer-to-peer systems.  ...  We are also grateful to Jeanine Casler, Stefan Birrer, David Choffnes and Kevin Livingston for their helpful comments on early drafts of this article.  ... 
doi:10.1109/tnet.2007.903986 fatcat:4eefknqtrzeido62vtryougzoq

Hidden state dynamics reveals metastability across the adult lifespan [article]

Keyu Chen, Qing Wang, Dong-Qiang Liu
2020 bioRxiv   pre-print
tool to reveal the metastability, the ability of the system to transition between different cognitive states, across the adult lifespan.  ...  Adult lifespan is accompanied by functional reorganization of brain networks, but the dynamic patterns behind this reorganization remain largely unclear.  ...  Acknowledgments This work was supported by the National Natural Science Foundation of China  ... 
doi:10.1101/2020.01.27.920652 fatcat:22khqrzvkffqjgszdzzd6gx7em

An analytical study of peer-to-peer media streaming systems

Yi-Cheng Tu, Jianzhong Sun, Mohamed Hefeeda, Sunil Prabhakar
2005 ACM Transactions on Multimedia Computing, Communications, and Applications (TOMCCAP)  
The unpredictable departure/failure of peers is a critical factor that affects the performance of P2P systems. We utilize the concept of peer lifespan to model peer failures.  ...  Hybrid streaming systems that combine the use of dedicated streaming servers and P2P networks were proposed to build on the advantages of both paradigms.  ...  ACKNOWLEDGMENTS The authors would like to thank Prof.  ... 
doi:10.1145/1111604.1111607 fatcat:pf4gqgrr4jhdpcdca7tzzx2r7e

Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans [article]

Yue Zhang, Anne Lanjuin, Suvagata R Chowdhury, Meeta Mistry, Carlos G Silva Garcia, Heather J Weir, Chia-Lin Lee, Caroline C Escoubas, Emina Tabakovic, William B Mair
2019 bioRxiv   pre-print
Finally, deleting the mitochondrial fission factor DRP-1 renders the animal refractory to the pro-aging effects of neuronal RAGA-1.  ...  Loss of RAGA-1 increases lifespan via maintaining mitochondrial fusion.  ...  Additionally, to determine the complexity of the mitochondrial 603 network, we focused on the Network and Junction Point attribute.  ... 
doi:10.1101/665190 fatcat:nrqlkhbrvvfbhopgfdktn5nntq

A Multicellular Network Mechanism for Temperature-Robust Food Sensing [article]

Dhaval S Patel, Giovanni Diana, Eugeni V Entchev, Mei Zhan, Hang Lu, QueeLim Ch'ng
2019 bioRxiv   pre-print
Mechanistically, specific regulations in this network change with temperature to maintain similar food-responsiveness in the lifespan output.  ...  This end-to-end robustness from environment to physiology is mediated by food- sensing neurons that communicate via TGF-β and serotonin signals to form a multicellular gene network.  ...  Acknowledgments We thank the Horvitz Lab, the Bargmann Lab, and the C. elegans Genetics Center, which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440) for reagents.  ... 
doi:10.1101/815373 fatcat:s4kdar62bbbejir6twq5cxv6pe

Structural covariance networks across the lifespan, from 6-94 years of age [article]

Elizabeth DuPre, R. Nathan Spreng
2016 bioRxiv   pre-print
Although structural covariance has been used to examine the development of brain networks in either adolescence or aging, no study to date has provided a lifespan perspective on the development of structural  ...  Here, we investigate the lifespan trajectories of structural covariance in six canonical neurocognitive networks default, dorsal attention, frontoparietal control, somatomotor, ventral attention, and visual  ...  As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or provided data but did not participate in analysis or writing of this report.  ... 
doi:10.1101/090233 fatcat:3bpr7i2jwrgylh7scw6hr42pge

A performance study of BitTorrent-like peer-to-peer systems

L. Guo, S. Chen, Z. Xiao, E. Tan, X. Ding, X. Zhang
2007 IEEE Journal on Selected Areas in Communications  
the BitTorrent-like system is unstable, and fluctuates significantly with the changes of the number of online peers. (3) Existing systems could provide unfair services to peers, where a peer with a higher  ...  decreasing peer arrival rate in a torrent, the service availability of the corresponding file becomes poor quickly, and eventually it is hard to locate and download this file. (2) Client performance in  ...  Some preliminary results of this work have been presented in [27] . We would like to thank Mikel Lzal for providing BitTorrent traces to us. We appreciate Oliver Spatscheck, Keith W.  ... 
doi:10.1109/jsac.2007.070116 fatcat:l7s4viqnm5frpjsdxckwjjkexa

Functional connectivity within and between n-back modulated regions: An adult lifespan PPI investigation [article]

Ekarin E. Pongpipat, Kristen M. Kennedy, Chris M. Foster, Maria A. Boylan, Karen M. Rodrigue
2020 bioRxiv   pre-print
These results suggest that FC is critical for engaging in cognitively demanding tasks, and its lack of sensitivity to healthy aging may provide a means to maintain cognition across the adult lifespan.  ...  This study contributes to the literature by examining a large, adult lifespan sample, increased levels of WM load, and additional investigation of connections within and between fronto-parietal and default  ...  To test whether there was an association between FC and n-back task performance across the adult lifespan, n-back performance using d' was regressed on FC of each PPI variable and network pair, age, and  ... 
doi:10.1101/2020.06.11.145219 fatcat:auh6frvtvjdt7lrpz3onmyhv3e

Measurements, analysis, and modeling of BitTorrent-like systems

Lei Guo, Songqing Chen, Zhen Xiao, Enhua Tan, Xiaoning Ding, Xiaodong Zhang
2005 Proceedings of the 5th ACM SIGCOMM conference on Internet measurement - IMC '05  
Our analysis of representative Bit-Torrent traffic provides several new findings regarding the limitations of BitTorrent systems: (1) Due to the exponentially decreasing peer arrival rate in reality, service  ...  widely with the peer population. (3) Existing systems could provide unfair services to peers, where peers with high downloading speed tend to download more and upload less.  ...  Bynum provided valuable comments on an early draft of the paper. This work is partially supported by the National Science Foundation under grants CNS-0098055, CNS-0405909, and CNS-0509054/0509061.  ... 
doi:10.1145/1330107.1330113 fatcat:tn3hudkyrndzno4doblpwsvrby

DNA Methylation Networks Underlying Mammalian Traits [article]

Amin Haghani, Ake T Lu, Caesar Z Li, Todd R Robeck, Katherine Belov, Charles E Breeze, Robert T Brooke, Shannon Clarke, Chris G Faulkes, Zhe Fei, Steven H Ferguson, Carrie J Finno (+31 others)
2021 bioRxiv   pre-print
Insights uncovered by this investigation have important implications for our understanding of the role of epigenetics in mammalian evolution, aging and lifespan.  ...  Analysis of the correlation between DNA methylation and species allowed us to construct phyloepigenetic trees for different tissues that parallel the phylogenetic tree.  ...  The lineage that eventually led to the emergence of the first modern humans, Homo erectus, about two million years ago, with the acquisition of a larger brain, higher cognitive abilities, and several unique  ... 
doi:10.1101/2021.03.16.435708 fatcat:eqyiaw675vcujazztpyenp4eky

Performance analysis of a hybrid media streaming system

Yi-Cheng Tu, Jianzhong Sun, Sunil Prabhakar, Nalini Venkatasubramanian
2003 Multimedia Computing and Networking 2004  
Recent research efforts have demonstrated the promising potential of building cost-effective media streaming systems on top of peer-to-peer (P2P) networks.  ...  The unpredictable departure/failure of peers is a critical factor that affects performance of P2P systems. To model peer failures in our system, we propose the concept of peer lifespan.  ...  ACKNOWLEDGMENTS The authors would like to thank Dr.  ... 
doi:10.1117/12.538806 fatcat:b2ivkdqznjbnblygjzbylohd3a

SynergyAge: a curated database for synergistic and antagonistic interactions of longevity-associated genes [article]

Gabriela Bunu, Dmitri Toren, Catalin Florentin Ion, Diogo Barardo, Larisa Sarghie, Laurentiu Gabriel Grigore, Joao Pedro de Magalhaes, Vadim Fraifeld, Robi Tacutu
2020 bioRxiv   pre-print
Unfortunately, based on observations so far, there is no simple method to predict the cumulative impact of genes on lifespan.  ...  While available lifespan data is continually accumulating, further understanding of the aging process is still limited by the poor understanding of epistasis and of the non-linear interactions between  ...  In order to allow the user to focus on a certain part of the network, the "Emphasize selection" button can fade out the nonselected nodes. .  ... 
doi:10.1101/2020.04.22.054767 fatcat:agaqsnxmozglnbq7mv2ixpf2li
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