398 Hits in 4.8 sec

Abnormal P300 in people with high risk of developing psychosis

Elvira Bramon, Madiha Shaikh, Matthew Broome, Julia Lappin, Daniel Bergé, Fern Day, James Woolley, Paul Tabraham, Mercè Madre, Louise Johns, Oliver Howes, Lucia Valmaggia (+4 others)
2008 NeuroImage  
Article Title: Abnormal P300 in people with high risk of developing psychosis.  ...  Please find attached a fully revised manuscript titled "Abnormal P300 in people with high risk of developing psychosis".  ...  populations with high risk of developing psychosis.  ... 
doi:10.1016/j.neuroimage.2007.12.038 pmid:18387827 fatcat:syvofttd25c2dcsqh54hf2ryoq

White matter alterations related to P300 abnormalities in individuals at high risk for psychosis: an MRI–EEG study

Paolo Fusar-Poli
2011 Journal of Psychiatry & Neuroscience  
for psychosis (with an "at-risk mental state" [ARMS]).  ...  Psychosis onset is characterized by white matter and electrophysiologic abnormalities. The relation between these factors in the development of illness is almost unknown.  ...  All authors approved publication of the article.  ... 
doi:10.1503/jpn.100083 pmid:21299920 pmcid:PMC3120892 fatcat:6eo6c5nwcbdlbf7d4kxfqhaele

Evolving Notions of Schizophrenia as a Developmental Neurocognitive Disorder

Larry J. Seidman, Allan F. Mirsky
2017 Journal of the International Neuropsychological Society  
Neurocognitive deficits are found in the premorbid phase in a substantial minority of pre-teenage youth who later develop schizophrenia, and they apparently worsen by the prodromal, high-risk phase in  ...  are used routinely in clinical assessment of individuals with schizophrenia.  ...  Seidman's contribution was supported by the Commonwealth Research Center of the Massachusetts Department of Mental Health, SCDMH82101008006. Conflicts of Interest: None  ... 
doi:10.1017/s1355617717001114 pmid:29198285 fatcat:ickkxdvnyrczjnsujzmicnaqoq

Neurobiology of early psychosis

Matcheri S. Keshavan, Gregor Berger, Robert B. Zipursky, Christos Pantelis, Stephen J. Wood
2005 British Journal of Psychiatry  
Functional and neurochemical brain abnormalities can also be seen in the premorbid and the early phases of the illness.  ...  Some changes, notably those in frontal and temporal lobes, can progress during the early phases of the illness.  ...  McGlashan Schizotypal components in people at high risk of Schizotypal components in people at high risk of developing schizophrenia: early findings from the developing schizophrenia: early findings from  ... 
doi:10.1192/bjp.187.48.s8 pmid:16055814 fatcat:jfbdsknuibfsnplz36747kzz2i

Prolonged P300 Latency in Antipsychotic-Free Subjects with At-Risk Mental States Who Later Developed Schizophrenia

Yuko Higuchi, Tomiki Sumiyoshi, Takahiro Tateno, Suguru Nakajima, Daiki Sasabayashi, Shimako Nishiyama, Yuko Mizukami, Tsutomu Takahashi, Michio Suzuki
2021 Journal of Personalized Medicine  
During the follow-up period, eight out of 33 subjects with ARMS developed overt psychosis (ARMS-P) while 25 did not (ARMS-NP). P300 latency of ARMS-P was significantly longer than that of ARMS-NP.  ...  We measured P300, an event-related potential, in subjects with at-risk mental states (ARMS) and aimed to determine whether P300 parameter can predict progression to overt schizophrenia.  ...  Acknowledgments: Special thanks to our colleagues, Tomonori Seo, Tomohiro Miyanishi in Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Science to help  ... 
doi:10.3390/jpm11050327 pmid:33919276 fatcat:24otdazxnrcghavm6vt57hudsy


Matej Oresic
2018 Schizophrenia Bulletin  
However, abnormal glucose homeostasis, hyperinsulinemia and accumulation of visceral fat are already detected in drug-naïve first episode psychosis (FEP) patients, independently of obesity.  ...  Overall Abstract: Schizophrenia is associated with a reduced life expectancy of 15-20 years due to a high prevalence of cardiovascular disease and metabolic syndrome.  ...  Abnormalities in the cardio-metabolic and immune system are well established in patients with schizophrenia, but it is unknown if abnormalities are present in people at risk of psychosis and at illness  ... 
doi:10.1093/schbul/sby014.173 fatcat:mbuvgbkeujcmrejfi6czytwekq

M69. Changes in Neural Measures of Emotion Processes Following Targeted Social Cognition Training

Abhishek Saxena, Erin Guty, David Dodell-Feder, Hong Yin, Kristen Haut, Mor Nahum, Christine Hooker
2017 Schizophrenia Bulletin  
This analysis aims to validate the use of graph analysis (GA) metrics in an Ultra High Risk of Psychosis (UHR) sample in order to inform future research in this area.  ...  A relation to PANSS scores is in line with limited evidence suggesting aberrant functional connectivity in UHR participants (Lord et al.  ...  Much less is known whether abnormalities exist in individuals at clinical high risk for psychosis (CHR), whether they are associated with conversion to psychosis, and whether they are observed in different  ... 
doi:10.1093/schbul/sbx022.064 fatcat:ma67j5x5erc6rdrh26r5r7tpw4

EEG-Based Measures in At-Risk Mental State and Early Stages of Schizophrenia: A Systematic Review

Andrea Perrottelli, Giulia Maria Giordano, Francesco Brando, Luigi Giuliani, Armida Mucci
2021 Frontiers in Psychiatry  
The identification of neuronal aberrations in subjects with a first episode of psychosis (FEP) and in those at ultra high-risk (UHR) or clinical high-risk (CHR) to develop a psychosis is crucial to implement  ...  Electrophysiological (EEG) abnormalities in subjects with schizophrenia have been largely reported.  ...  " OR "evoked potential" OR "evoked-response") AND ("ultra-high risk psychosis" OR "clinical high risk psychosis" OR "prodromal psychosis" OR "first episode schizophrenia" OR "first episode psychosis" OR  ... 
doi:10.3389/fpsyt.2021.653642 pmid:34017273 pmcid:PMC8129021 fatcat:j4dr4rndobazhmc5y3zpmfki6q

Efeitos comportamentais, cognitivos e psicofisiológicos dos canabinoides: relevância para a psicose e a esquizofrenia

R. Andrew Sewell, Patrick D. Skosnik, Icelini Garcia-Sosa, Mohini Ranganathan, Deepak Cyril D'Souza
2010 Revista Brasileira de Psiquiatria  
with a high risk for developing psychosis (either because of family history or prodromal symptoms) have higher rates of psychotic outcomes associated with cannabis use  ...  Similarly, Cadenhead et al., reported that individuals with a high risk for developing psychosis who used cannabis use were 10 times more likely convert to psychosis than individuals who did not use cannabis  ... 
doi:10.1590/s1516-44462010000500005 fatcat:vne5xacpbzamtacs4tbqkfl7ji

Reduced P300 amplitude during retrieval on a spatial working memory task in a community sample of adolescents who report psychotic symptoms

Caroline Rawdon, Jennifer Murphy, Mathieu M Blanchard, Ian Kelleher, Mary C Clarke, Fergal Kavanagh, Mary Cannon, Richard AP Roche
2013 BMC Psychiatry  
Amplitude of the P300 component was reduced at high load for the late P300 timeframe at electrode sites Pz and POz.  ...  Research suggests that many of the same risk factors for schizophrenia are shared with individuals from the general population who report psychotic symptoms.  ...  Axis-1 disorder [7] , a finding which is in keeping with research in clinic-presenting young people with at risk mental states [8] [9] [10] [11] , who are considered to be at 'ultra high risk' for psychosis  ... 
doi:10.1186/1471-244x-13-125 pmid:23634909 pmcid:PMC3666949 fatcat:qeozqkmg3veupgeykxnat3h3t4

Language processing abnormalities in adolescents with psychotic-like experiences: An event related potential study

Jennifer Murphy, Mathieu M. Blanchard, Caroline Rawdon, Fergal Kavanagh, Ian Kelleher, Mary C. Clarke, Richard A.P. Roche, Mary Cannon
2012 Schizophrenia Research  
Language impairments are a well established finding in patients with schizophrenia and in individuals at-risk for psychosis.  ...  In particular, adolescents with PLEs have been shown to be at an increased risk for later psychosis.  ...  Conflict of interest The authors report no conflict of interest. Acknowledgements We thank NUI Maynooth and the Clinical Research Centre Beaumont Hospital for the use of their facilities.  ... 
doi:10.1016/j.schres.2012.01.017 pmid:22330177 fatcat:xdd32noxdzat5np2lk74rgd7xa

Abnormal frontoparietal synaptic gain mediating the P300 in patients with psychotic disorder and their unaffected relatives

Álvaro Díez, Siri Ranlund, Dimitris Pinotsis, Stella Calafato, Madiha Shaikh, Mei-Hua Hall, Muriel Walshe, Ángel Nevado, Karl J. Friston, Rick A. Adams, Elvira Bramon
2017 Human Brain Mapping  
Impairments in the P300 potential are well documented in psychosis. Intrinsic (self-)connectivity in a frontoparietal cortical hierarchy during a P300 experiment was investigated.  ...  risk effects, as well as their interactions with task condition were identified.  ...  All authors declare that they have no conflicts of interest.  ... 
doi:10.1002/hbm.23588 pmid:28345275 pmcid:PMC5918301 fatcat:yaxldhp6jjdinb4snfn3q6cvzm

Early Detection and Prevention of Schizophrenic Psychosis—A Review

Martin Lennart Schulze Westhoff, Johannes Ladwig, Johannes Heck, Rasmus Schülke, Adrian Groh, Maximilian Deest, Stefan Bleich, Helge Frieling, Kirsten Jahn
2021 Brain Sciences  
Despite the increasing knowledge of the neurobiological mechanisms involved in the development of psychotic disorders, further research efforts with large population-based study designs are needed to identify  ...  In addition to established diagnostic tools, neurobiological factors in the development of schizophrenic psychoses are increasingly being investigated.  ...  Over the course of the last few years, numerous working groups primarily addressed the question of how people with an increased risk of developing schizophrenic psychosis could be identified at an early  ... 
doi:10.3390/brainsci12010011 pmid:35053755 pmcid:PMC8774083 fatcat:ktaaqja2s5dixabl5emwgfh53i

Page 4768 of Psychological Abstracts Vol. 88, Issue 12 [page]

2001 Psychological Abstracts  
of two-dimensional topographic scalp-distribution of P300 amplitude and la- tency relate to genetic risk for schizophrenia. 34 unrelated normal control Ss with a standard auditory oddball paradigm and  ...  —Event-related potentials (ERPs) during an auditory oddball task were investigated in 42 patients with schizophrenia and in 62 of their healthy siblings to explore the question of whether abnormalities  ... 

Electrophysiological Endophenotypes for Schizophrenia

Emily M. Owens, Peter Bachman, David C. Glahn, Carrie E. Bearden
2016 Harvard Review of Psychiatry  
signaling and GABA-ergic inhibition in the pathophysiology of schizophrenia.  ...  They can be assessed at numerous levels of analysis; here, we review electrophysiological endophenotypes that have shown promise in helping us understand schizophrenia from a more mechanistic point of  ...  Recently, deficits in MMN have been demonstrated in individuals at clinical or genetic high risk for psychosis 124, 131 and have been shown to predict psychosis onset in clinically high risk individuals  ... 
doi:10.1097/hrp.0000000000000110 pmid:26954597 pmcid:PMC4785844 fatcat:v3nvaqun5rguxmgv754ufvtfrq
« Previous Showing results 1 — 15 out of 398 results