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T J Karttunen, A Miettinen
1996 Gut  
In one case a specimen from duodenal bulbous showed severe villous atrophy and an increase of intraepithelial lymphocytes.  ...  Protected by copyright. http://gut.bmj.com/ Gut: first published as 10.1136/gut.38.4.629-a on 1 April 1996. Downloaded from  ... 
doi:10.1136/gut.38.4.629-a pmcid:PMC1383129 fatcat:hste72tcbfhcrnhas6qvtq27im

Role ofHelicobacter pyloriand interleukin 6 -174 gene polymorphism in dyslipidemia: a case–control study

Vesa-Matti Pohjanen, Olli-Pekka Koivurova, Seppo E Niemelä, Riitta A Karttunen, Tuomo J Karttunen
2016 BMJ Open  
In the genotype subgroup analyses, a similar association between H. pylori infection and HDL serum levels was seen within the IL-6 -174 CC genotype group (HDL 0.72 vs 1.06 mmol/L, respectively; p<0.001  ...  Positive H. pylori status was based on a positive serology together with a positive bacterial culture, positive histology or a positive PCR test.  ...  of the mean value, one would need a sample size of 91 patients in each group.  ... 
doi:10.1136/bmjopen-2015-009987 pmid:26781506 pmcid:PMC4735314 fatcat:hnsv3nbd55fsjcbsixohgkluzy

AlphaFold2: A role for disordered protein prediction? [article]

Carter J. Wilson, Wing-Yiu Choy, Mikko Karttunen
2021 bioRxiv   pre-print
Aligned Error (PAE) provides a much more rigorous metric.  ...  We find that a naive use of Dictionary of Secondary Structure of Proteins (DSSP) to separate ordered from disordered regions leads to a dramatic overestimation in disorder content, and that the Predicted  ...  A helix with a low pLDDT may be more transient, existing frequently in a disordered, unfolded state, than a helix with a high pLDDT and conversely, a coiled region with a high pLDDT, may suggest a disorder-order  ... 
doi:10.1101/2021.09.27.461910 fatcat:suvxestbinb5pjno7s5rrfhhke

Could Helicobacter pylori infection increase the risk of coronary heart disease by modifying serum lipid concentrations?

S. Niemela, T. Karttunen, T. Korhonen, E. Laara, R. Karttunen, M. Ikaheimo, Y. A. Kesaniemi
1996 Heart  
Design-A case-control study. Setting-Northern Finland (about 650 000 inhabitants).  ...  FinlandNiemela, Karttunen, Korhonen, Laara, Karttunen, Ikaheimo, KesaniemiTable 1Distribution of some determinants of coronary heart disease in patients with CHD and their controls who were seropositive  ...  Department of Internal Medicine, University of Oulu, Finland S Niemela T Korhonen M Ikaheimo Y A Kesaniemi Department of Pathology, University of Oulu, Finland T Karttunen Public Health Science  ... 
doi:10.1136/hrt.75.6.573 pmid:8697159 pmcid:PMC484379 fatcat:dvbvuqaewzf5flqlhbqmhj6uvu

A nonlinear couple stress-based sandwich beam theory [article]

Bruno Reinaldo Goncalves, Anssi T. Karttunen, Jani Romanoff
2019 arXiv   pre-print
A micromechanical approach based on the structural analysis of a unit cell is derived and utilized to obtain the stiffness properties of selected prismatic cores.  ...  A two-node finite element interpolated with linear and cubic shape functions is proposed and its stiffness and geometric stiffness matrices are derived.  ...  The axial N , periodic shear Q 0 and two independent bending stress resultants M 0 and M l are defined (Fig 2) N = A σ x dz, Q 0 = K s A σ xz dz, M 0 = A σ x z + 1 2 m xy dz, M l = 1 2 A m xy dz (  ... 
arXiv:1903.07805v1 fatcat:yv2heehp4rg4zkt2h4zgfd4e7m

Ten year follow up study of lymphocytic gastritis: further evidence on Helicobacter pylori as a cause of lymphocytic gastritis and corpus gastritis

S Niemela, T Karttunen, T Kerola, R Karttunen
1995 Journal of Clinical Pathology  
Airns-To examine the course of lymphocytic gastritis and its relation to Helicobacter pylori (H pylon) infection in a 10 year follow up.  ...  One patient had undergone a gastric resection because of a gastric ulcer and she had a normal appearing resected stomach.  ...  A lymphoid follicle was defined as an aggregate of lymphocytes with a germinal centre.  ... 
doi:10.1136/jcp.48.12.1111 pmid:8567997 pmcid:PMC503037 fatcat:tbbe7tqhqvel5prvhyye3a2tqu

Cell aggregation: Packing soft grains

J. A. Åström, M. Karttunen
2006 Physical Review E  
even at high a pressure.  ...  A dry foam has a high density of bubbles ͑i.e., a high porosity͒ which are interlocked, or jammed, such that they cannot flow past each other ͓5͔.  ... 
doi:10.1103/physreve.73.062301 pmid:16906885 fatcat:kgh75lzjercofbgjawbtgomshi

Fe3Se4: A Possible Ferrimagnetic Half-Metal? [article]

Girish C. Tewari, Divya Srivastava, Reijo Pohjonen, Otto Mustonen, Antti J. Karttunen, Johan Lindén, Maarit Karppinen
2020 arXiv   pre-print
The electrical resistivity follows exponentially suppressed electron-magnon scattering mechanism in the low-temperature regime and show a magnetoresistance effect that changes the sign from negative to  ...  Our optimized lattice parameters, a=6.45 Å, b=3.67 Å, c=11.74 Å and β=92.84 0 , are somewhat larger than the experimental values of a=6.20 Å, b=3.53 Å, c=11.38 Å, and β=91.83 [25, 30] .  ...  Experimentally, we observe a crossover from a negative to a positive MR effect with decreasing temperature.  ... 
arXiv:2007.04736v1 fatcat:3mdscodyjjdbxfemkiq5dth3jy

VRChem: A Virtual Reality Molecular Builder

Otso Pietikäinen, Perttu Hämäläinen, Jaakko Lehtinen, Antti J. Karttunen
2021 Applied Sciences  
Virtual reality provides a powerful way to visualize the three-dimensional, atomic-level structures of molecules and materials.  ...  The open-source software, named VRChem, was developed primarily for building, visualizing and manipulating organic molecules using a head-mounted virtual reality system.  ...  virtual button, or a hand gesture, such as a thumbs up.  ... 
doi:10.3390/app112210767 fatcat:2nxxng3wyrghpfqcxd65nknosy

Thermoplasmonic behavior of semiconductor nanoparticles: A comparison with metals [article]

Vaibhav Thakore, Janika Tang, Kevin Conley, Tapio Ala-Nissila and Mikko Karttunen
2018 arXiv   pre-print
Results show a redshift in the scattering and absorption resonances for the DL model while the DCP model presents a blueshift.  ...  A number of applications in nanoplasmonics utilize noble metals, gold (Au) and silver (Ag), as the materials of choice.  ...  These are computed as [29] a x1 = a x0 exp(−T /230) [1 − exp(−E x1 /k B T )] (16) and a x2 = a x0 exp(−T /230)[1 − exp(−E x2 /k B T )]/8. (17) The exciton binding energies of the fundamental (E x1 )  ... 
arXiv:1807.00881v1 fatcat:abk7nafwfvd4tfc5yo54ntva4y

Cholesterol Sequestration by Xenon Leads to Lipid Raft Destabilization [article]

A. D. Reyes-Figueroa, Mikko Karttunen, J. C. Ruiz-Suarez
2020 bioRxiv   pre-print
At a concentration of 2 Xe/lipid we observed an unexpected result: Spontaneous nucleation of Xe nanoclusters which then rapidly plunged into the bilayer.  ...  S2 A snapshot of the lateral view of a lipid raft in a membrane at the end of the 200 ns simulation at 323 K.  ...  The long-range electrostatics interactions were calculated using the particle mesh Ewald algorithm [50] with a 1.0 nm cutoff, a Fourier spacing of 0.15 nm and a sixth order interpolation.  ... 
doi:10.1101/2020.05.04.077727 fatcat:asuwdfwlkncuxpphdcpak4qohi

Crumpling of a Stiff Tethered Membrane

J. A. Åström, J. Timonen, Mikko Karttunen
2004 Physical Review Letters  
We observe that close to the stiffness divergence there appears a crossover beyond which the elastic behavior of a tethered membrane becomes similar to that of dry granular media.  ...  first-principles numerical simulation model for crumpling of a stiff tethered membrane is introduced.  ...  Figure 1 shows a snapshot from a simulation that displays a few wrinkles at t 200.  ... 
doi:10.1103/physrevlett.93.244301 pmid:15697819 fatcat:omqgzj4zu5cxro753p3xihjibq

Binding of disordered proteins to a protein hub

Elio A. Cino, Ryan C. Killoran, Mikko Karttunen, Wing-Yiu Choy
2013 Scientific Reports  
A set of ambiguous shifts for all three residues is reported in the A2 row. Turn potentials are from 13 .  ...  A set of ambiguous shifts for both residues is reported in the L15 row. S15 and S20 have similar H N and Hβ shifts.  ... 
doi:10.1038/srep02305 pmid:23892546 pmcid:PMC3725505 fatcat:jz573ac7jjbytivy2ssuu34jfy

Spatio-temporal dynamics in a Turing model [chapter]

T. Leppänen, M. Karttunen, R. A. Barrio, K. Kaski
2011 Unifying Themes in Complex Systems  
In addition, we study the interaction of instabilities in a tristable system.  ...  In this paper we study numerically two-dimensional spatio-temporal pattern formation in a generic Turing model, by investigating the dynamical behavior of a monostable system in the presence of Turing-Hopf  ...  ) and a Hopf bifurcation in a monostable system.  ... 
doi:10.1007/978-3-642-17635-7_26 fatcat:tu6i3vit3bdexda7ucumfoabq4

Semiconducting Clathrates Meet Gas Hydrates: Xe24[Sn136]

Antti J. Karttunen, Thomas F. Fässler
2014 Chemistry - A European Journal  
Semiconducting group 14 clathrates are inorganic host-guest materials with a close structural relationship to gas hydrates.  ...  Here we utilize this inherent structural relationship to derive a new class of porous semiconductor materials: noble gas filled group 14 clathrates (Ng x [M 136 ], Ng = Ar, Kr, Xe and M = Si, Ge, Sn).  ...  Acknowledgements A. J. K thanks Dr. Silvia Casassa and Dr.  ... 
doi:10.1002/chem.201402251 pmid:24789147 fatcat:oays2vnvqrf3bafjvdvrke5yti
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