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Women with autistic-spectrum disorder: magnetic resonance imaging study of brain anatomy

Michaelc. Craig, Shahid H. Zaman, Eileen M. Daly, William J. Cutter, Dene M. W. Robertson, Brian Hallahan, Fiona Toal, Suzie Reed, Anita Ambikapathy, Mick Brammer, Clodagh M. Murphy, Declan G. M. Murphy
2007 British Journal of Psychiatry  
Our understanding of anatomical differences in people with autistic-spectrum disorder, is based on mixed-gender or male samples.  ...  Method We compared the brain anatomy of 14 adult women with autistic-spectrum disorder with 19 controls using volumetric magnetic resonance imaging and voxel-based morphometry Results Women with autistic-spectrum  ...  ACKNOWLEDGEMENTS ACKNOWLEDGEMENTS The authors thank the people with autistic-The authors thank the people with autisticspectrum disorder who took part in the study, the spectrum disorder who took part  ... 
doi:10.1192/bjp.bp.106.034603 pmid:17766762 fatcat:545sjfwyjjf3jlbwutp5aoc6ve

Structural MRI in Autism Spectrum Disorder

RONG CHEN, YUN JIAO, EDWARD H. HERSKOVITS
2011 Pediatric Research  
Magnetic resonance (MR) examination provides a powerful tool for investigating brain structural changes in children with autism spectrum disorder (ASD).  ...  We review recent advances in the understanding of structural MR correlates of ASD.  ...  A utism spectrum disorder (ASD) (1,2) is a heterogeneous disorder (or collection of related disorders) of multifactorial etiology, with great range in severity of symptoms.  ... 
doi:10.1203/pdr.0b013e318212c2b3 pmid:21289538 pmcid:PMC3081653 fatcat:cbpc5hsctndmjkyoee6bap4wwe

Meta-analysis of Gray Matter Abnormalities in Autism Spectrum Disorder

Esther Via, Joaquim Radua, Narcis Cardoner, Francesca Happé, David Mataix-Cols
2011 Archives of General Psychiatry  
Context: Studies investigating abnormalities of regional gray matter volume in autism spectrum disorder (ASD) have yielded contradictory results.  ...  Objectives: To conduct a quantitative meta-analysis of voxel-based morphometry studies exploring gray matter volume abnormalities in ASD, to examine potential neurobiological differences among ASD subtypes  ...  autistic spectrum.  ... 
doi:10.1001/archgenpsychiatry.2011.27 pmid:21464365 fatcat:7uviqiuuknhgzpylj7oeil7e6a

Brain growth rate abnormalities visualized in adolescents with autism

Xue Hua, Paul M. Thompson, Alex D. Leow, Sarah K. Madsen, Rochelle Caplan, Jeffry R. Alger, Joseph O'Neill, Kishori Joshi, Susan L. Smalley, Arthur W. Toga, Jennifer G. Levitt
2011 Human Brain Mapping  
Autism spectrum disorder is a heterogeneous disorder of brain development with wide ranging cognitive deficits.  ...  With longitudinal magnetic resonance imaging (MRI), we mapped an anomalous developmental trajectory of the brains of autistic compared with those of typically developing children and adolescents.  ...  INTRODUCTION Autism spectrum disorder is a complex neurodevelopmental disorder with a lifelong impact.  ... 
doi:10.1002/hbm.21441 pmid:22021093 pmcid:PMC4144412 fatcat:whoptahluvgi3cwwuqxc3jpmq4

ANS: Aberrant Neurodevelopment of the Social Cognition Network in Adolescents with Autism Spectrum Disorders

Yawei Cheng, Kun-Hsien Chou, Yang-Teng Fan, Ching-Po Lin, Thomas Burne
2011 PLoS ONE  
Methodology/Principal Findings: We enrolled 25 male adolescents with high functioning ASD and 25 typically developing controls for voxel-based morphometric analysis of structural magnetic resonance image  ...  Results indicate that there is an imbalance of regional gray matter volumes and concentrations along with no global brain enlargement in adolescents with high functioning ASD relative to controls.  ...  Acknowledgments The authors thank the participants and their parents who were included in the study. The authors also acknowledge MR technique support from the MRI Core Laboratory, NYMU.  ... 
doi:10.1371/journal.pone.0018905 pmid:21541322 pmcid:PMC3082537 fatcat:rpilrbyb3fczrfvebqsztxqk3e

Age-related differences in white matter diffusion measures in autism spectrum condition

Abigail Thompson, Asal Shahidiani, Anne Fritz, Jonathan O'Muircheartaigh, Lindsay Walker, Vera D'Almeida, Clodagh Murphy, Eileen Daly, Declan Murphy, Steve Williams, Sean Deoni, Christine Ecker
2020 Molecular Autism  
Here, we employed a spatially unbiased tract-based spatial statistics (TBSS) approach to examine age-related differences in white matter connectivity in a sample of 41 individuals with ASC, and 41 matched  ...  Autism spectrum condition (ASC) is accompanied by developmental differences in brain anatomy and connectivity.  ...  childhood and adolescence in autistic males.  ... 
doi:10.1186/s13229-020-00325-6 pmid:32423424 fatcat:szugdy2m35bwhaifa7szdfjvxi

Impaired Structural Connectivity of Socio-Emotional Circuits in Autism Spectrum Disorders: A Diffusion Tensor Imaging Study

Stephanie H. Ameis, Jin Fan, Conrad Rockel, Aristotle N. Voineskos, Nancy J. Lobaugh, Latha Soorya, A. Ting Wang, Eric Hollander, Evdokia Anagnostou, Xi-Nian Zuo
2011 PLoS ONE  
Citation: Ameis SH, Fan J, Rockel C, Voineskos AN, Lobaugh NJ, et al. (2011) Impaired Structural Connectivity of Socio-Emotional Circuits in Autism Spectrum Disorders: A Diffusion Tensor Imaging Study.  ...  Voxel-wise analyses comparing ASD with controls in: (i) the full cohort (ii), children only (#12 yrs.), and (iii) adolescents only (.12 yrs.) were performed, followed by tract-specific comparisons.  ...  Nadia Tanel (Holland Bloorview Kids Rehabilitation Hospital) for assistance with data organization.  ... 
doi:10.1371/journal.pone.0028044 pmid:22132206 pmcid:PMC3223195 fatcat:52oxsshr5bamjhhoankx5zmsiy

Alteration of functional connectivity in autism spectrum disorder: effect of age and anatomical distance

Zhiliang Long, Xujun Duan, Dante Mantini, Huafu Chen
2016 Scientific Reports  
Autism spectrum disorder (ASD) is a neurodevelopment disorder characterized by deficits in communication and social interaction, along with repetitive patterns of behavior and interests 1 .  ...  Autism spectrum disorder (ASD) is associated with disruption of local-and long-range functional connectivity (FC).  ...  Reduced FC of cerebellum found in the current study was in accordance with those studies, corroborating the idea that this brain structure has a crucial role in ASD.  ... 
doi:10.1038/srep26527 pmid:27194227 pmcid:PMC4872225 fatcat:rzligau5braifgkthw4jfrovva

Abnormalities of Gray Matter Volume and Its Correlation with Clinical Symptoms in Adolescents with High-Functioning Autism Spectrum Disorder

Xiaoxin Zhao, Shuyi Zhu, Yang Cao, Peipei Cheng, Yuxiong Lin, Zhixin Sun, Wenqing Jiang, Yasong Du
2022 Neuropsychiatric Disease and Treatment  
Voxel-based morphometry was applied to investigate regional GMV alterations. The participants with ASD were examined for the severity of clinical symptoms with Autism Behavior Checklist (ABC).  ...  Here, the current study examined GMV alterations in whole brain and their correlations with clinical symptoms in a relatively large and homogeneous sample of participants with ASD matched typically developing  ...  and the Scientific Research Project of Shanghai Municipal Health Commission (20194Y0071).  ... 
doi:10.2147/ndt.s349247 pmid:35401002 pmcid:PMC8983641 fatcat:rikoeoums5bzndvkwyauhquuky

Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey

Marwa M. T. Ismail, Robert S. Keynton, Mahmoud M. M. O. Mostapha, Ahmed H. ElTanboly, Manuel F. Casanova, Georgy L. Gimel'farb, Ayman El-Baz
2016 Frontiers in Human Neuroscience  
This survey demonstrates the absence of consistent pathology in the brains of autistic children and lack of research investigations in patients under 2 years of age in the literature.  ...  This paper reviews recent applications of structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI), to study autism spectrum disorder (ASD).  ...  Adolescence Volumetric and voxel-wise cerebral changes have been investigated in a number of publications.  ... 
doi:10.3389/fnhum.2016.00211 pmid:27242476 pmcid:PMC4862981 fatcat:dxitkkqknrh4do6djuvlawxez4

Developmental brain structural atypicalities in autism: a voxel-based morphometry analysis

Hui Wang, Zeng-Hui Ma, Ling-Zi Xu, Liu Yang, Zhao-Zheng Ji, Xin-Zhou Tang, Jing-Ran Liu, Xue Li, Qing-Jiu Cao, Jing Liu
2022 Child and Adolescent Psychiatry and Mental Health  
Background Structural magnetic resonance imaging (sMRI) studies have shown atypicalities in structural brain changes in individuals with autism spectrum disorder (ASD), while a noticeable discrepancy in  ...  Methods The current study investigated the atypical structural brain features of autistic individuals who aged 6–30 years old.  ...  All authors contributed to the discussion of the manuscript. All authors read and approved the final manuscript.  ... 
doi:10.1186/s13034-022-00443-4 pmid:35101065 pmcid:PMC8805267 fatcat:7bsb5qfpgbbwfmvkpqdfkm7nza

Increased Gray Matter Volume and Resting-State Functional Connectivity in Somatosensory Cortex and their Relationship with Autistic Symptoms in Young Boys with Autism Spectrum Disorder

Jia Wang, Kuang Fu, Lei Chen, Xujun Duan, Xiaonan Guo, Heng Chen, Qiong Wu, Wei Xia, Lijie Wu, Huafu Chen
2017 Frontiers in Physiology  
Autism spectrum disorder (ASD) has been widely recognized as a complex neurodevelopmental disorder.  ...  A large number of neuroimaging studies suggest abnormalities in brain structure and function of patients with ASD, but there is still no consistent conclusion.  ...  We used a combined methods including voxel-based morphometric (VBM) technique along with rs-fcMRI to investigate whether brain regions with structural alterations in ASD children also existing abnormal  ... 
doi:10.3389/fphys.2017.00588 pmid:28861001 pmcid:PMC5559537 fatcat:a4or6z2lgzao5kd5a2g7a33pay

Impaired White Matter Integrity and Social Cognition in High-Function Autism: Diffusion Tensor Imaging Study

Woo Young Im, Ji Hye Ha, Eun Joo Kim, Keun-Ah Cheon, Jaeil Cho, Dong-Ho Song
2018 Psychiatry Investigation  
This aberrant functional connectivity in autism spectrum disorders (ASD) can be explained by impaired integrity of white matter tracts that link distant regions of the networks.  ...  Objective It is known that many of the cognitive and social deficits associated with autism can arise from abnormal functional connectivity between brain networks.  ...  Acknowledgements This study was supported by a faculty research grant of Yonsei University College of Medicine (6-2008-0299).  ... 
doi:10.30773/pi.2017.08.15 pmid:29486546 pmcid:PMC5900363 fatcat:3c6hiy2ls5bmhoaqriipe7sfm4

Structural magnetic resonance imaging data do not help support DSM-5 autism spectrum disorder category

Laura Pina-Camacho, Sonia Villero, Leticia Boada, David Fraguas, Joost Janssen, Maria Mayoral, Cloe Llorente, Celso Arango, Mara Parellada
2013 Research in Autism Spectrum Disorders  
entities with specific brain structural abnormalities.  ...  Research in Autism Spectrum Abstract: This systematic review aims to determine whether or not structural magnetic resonance imaging (sMRI) data support the DSM-5 proposal of an Autism Spectrum Disorder  ...  These methods were followed up by voxel-based approaches such as voxel-based morphometry (VBM) (Whitwell, 2009) , which allows whole brain exploration of structural differences and thus does not depend  ... 
doi:10.1016/j.rasd.2012.08.013 fatcat:kso7f3ecsbcrzo7v4cmkhnhofu

Changes in grey matter development in autism spectrum disorder

Ellen Greimel, Barbara Nehrkorn, Martin Schulte-Rüther, Gereon R. Fink, Thomas Nickl-Jockschat, Beate Herpertz-Dahlmann, Kerstin Konrad, Simon B. Eickhoff
2012 Brain Structure and Function  
Results on grey matter (GM) structural alterations in autism spectrum disorder (ASD) are inconclusive.  ...  Here, we aimed to examine regional GM volumes in a large sample of children, adolescents, and adults with ASD.  ...  Acknowledgments We are grateful to all participants with their families who took part in this study.  ... 
doi:10.1007/s00429-012-0439-9 pmid:22777602 pmcid:PMC3695319 fatcat:ncdgunytezcmdcfazqk2khrzq4
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