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A temporal database mediator for protocol-based decision support

J H Nguyen, Y Shahar, S W Tu, A K Das, M A Musen
1997 Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium  
To meet the data-processing requirements for protocol-based decision support, a clinical data-management system must be capable of creating high-level summaries of time-oriented patient data, and of retrieving  ...  The new module can be used as a standalone system for retrieving both primitive and abstracted time-oriented data, or can be embedded in a larger computational framework for protocol-based reasoning.  ...  We are grateful to Lyn Dupr6 for editing this manuscript.  ... 
pmid:9357636 pmcid:PMC2233432 fatcat:ar5twfb36ba33bgnps3eehhbyu

A temporal-abstraction mediator for protocol-based decision-support systems

A K Das, Y Shahar, S W Tu, M A Musen
1994 Proceedings. Symposium on Computer Applications in Medical Care  
We show that other computer methods for the detection of temporal abstractions do not scale up to the data- and knowledge-intensive environments of protocol-based decision-support systems.  ...  To overcome this obstacle, we have designed a data-interpretation module that can be embedded in a general architecture for protocol-based reasoning and that can support the fundamental task of detecting  ...  This work has been supported in part by grant HS06330 from the Agency for Health Policy and Research, and by grants LM05208 and LM07033 from the National Library of Medicine.  ... 
pmid:7949943 pmcid:PMC2247875 fatcat:g6h2pwk73jat5gck35rwis6rsy

A Temporal Query System for Protocol-Directed Decision Support

A. K. Das, M. A. Musen
1994 Methods of Information in Medicine  
In this paper, we outline an algebra that maintains a consistent relational representation of temporal data and that allows the type of temporal queries needed for protocol-directed decision support.  ...  Abstract:Chronus is a query system that supports temporal extensions to the Structured Query Language (SQL) for relational databases.  ...  This work has been supported in part by grant HS06330 from the Agency for Health Policy and Research, and by grants LM05208 and LM 07033 from the National Library of Medicine. Dr.  ... 
doi:10.1055/s-0038-1635036 fatcat:ueeiwphcuvdvxji3jozkdkoqaq

Timing Is Everything: Temporal Reasoning and Temporal Data Maintenance in Medicine [chapter]

Yuval Shahar
1999 Lecture Notes in Computer Science  
I demonstrate one integration approach by presenting a new architecture, a temporal mediator, which combines temporal reasoning and temporal maintenance, and integrates the management of clinical databases  ...  In this paper, I emphasize the crucial role of temporal-reasoning and temporal-maintenance tasks for modern medical information and decision support systems.  ...  Shahar has been supported by grants LM06245 from the National Library of Medicine and IRI-9528444 from the National Science Foundation.  ... 
doi:10.1007/3-540-48720-4_3 fatcat:yccwapuxpffhthdxp3tip3zl24

Knowledge sharing and negotiation support in multiperson decision support systems

Matthias Jarke
1986 Decision Support Systems  
A number of DSS for supporting decisions by more than one person have been proposed.  ...  Based on a literature review and recent experience with a number of multiperson DSS prototypes, artificial intelligence-based message-passing protocols are compared with database-centered approaches and  ...  This concept is being implemented in MEDIATOR, a multicriteria-based micro-mainframe DSS for negotiation support .  ... 
doi:10.1016/0167-9236(86)90125-9 fatcat:eildcdfzbvaj7ecbzg74o4die4

From guideline modeling to guideline execution: defining guideline-based decision-support services

S W Tu, M A Musen
2000 Proceedings. AMIA Symposium  
We describe our task-based approach to defining the guideline-based decision-support services that the EON system provides.  ...  Based on the tasks and the guideline model, we define a guideline-execution architecture and a model of interactions between a decision-support server and clients that invoke services provided by the server  ...  Acknowledgments This work has been supported in part by grantiLM05708 from National Library of Medicine, a grant from FastTrack Systems, Inc., and DARPA contract #N66001-94-D6052.  ... 
pmid:11080007 pmcid:PMC2243940 fatcat:cn6yakexfbdahomha5at7eu23e

Timing is everything. Time-oriented clinical information systems

Y Shahar, C Combi
1998 Western Journal of Medicine  
Such collaboration could provide a common ground and useful areas for future research and development. We conclude with our view of future research directions.  ...  Both of these research areas include efforts to model time, temporal entities, and temporal queries.  ...  of a relational database tuple, in a temporal extension of the database relational model, to support clinical databases used for decision-support application. 6 In such approaches, complex temporal  ... 
pmid:9499744 pmcid:PMC1304838 fatcat:ozpe67zltjhill4rneyja54i74

Idan: A Distributed Temporal-Abstraction Mediator for Medical Databases [chapter]

David Boaz, Yuval Shahar
2003 Lecture Notes in Computer Science  
A temporal-abstraction database mediator is a modular approach designed for answering abstract, time-oriented queries.  ...  ., clinicians, researchers), or decision support applications (e.g., diagnosis, therapy, quality assessment), who need to interpret large amounts of time-oriented data by providing a useful method for  ...  This research was supported in part by NIH award No. LM-06806. We thank Samson Tu and Martin O'connor for useful discussions regarding the Chronus-II and RASTA systems, and Drs.  ... 
doi:10.1007/978-3-540-39907-0_3 fatcat:2u3zs4nmqnarrccbuwrryaehdu

EON: A Component-Based Approach to Automation of Protocol-Directed Therapy

Mark A. Musen, Samson W. Tu, Amar K. Das, Yuval Shahar
1996 JAMIA Journal of the American Medical Informatics Association  
P rovision of, automated support for planning protocol-directed therapy requires a computer program to take as input clinical data stored in an electronic patient-record system and to generate as output  ...  recommendations for therapeutic interventions and laboratory testing that are defined by applicable protocols.  ...  carried out at Stanford University to model the therapy-planning task and to demonstrate a component-based architecture for building protocol-based decision-support systems.  ... 
doi:10.1136/jamia.1996.97084511 pmid:8930854 pmcid:PMC116322 fatcat:5wg3bz5nunezjlgjvya55yeely

Temporal reasoning and temporal data maintenance in medicine: Issues and challenges

Carlo Combi, Yuval Shahar
1997 Computers in Biology and Medicine  
Two main research directions can be noted: Temporal reasoning, which supports various temporal inference tasks (e.g., temporal abstraction, time-oriented decision support, forecasting, data validation)  ...  and fruitful areas for future research.  ...  Acknowledgments This work was partially supported by contributions from the Department of Mathematics and Computer Science, University of Udine, Italy, and by grants LM05708 and LM06245 from the National  ... 
doi:10.1016/s0010-4825(96)00010-8 pmid:9397339 fatcat:hsh77ztjovbjpgvriqtsxmt7hy

Domain Ontologies in Software Engineering: Use of Protégé with the EON Architecture

M. A. Musen
1998 Methods of Information in Medicine  
We illustrate the approach by describing the development of EON, a set of middleware components that automate various aspects of protocol-directed therapy.  ...  The Protege approach allows domain ontologies to inform the total software-engineering process, and for ontologies to be shared among a variety of problem-solving components.  ...  Ray Fergerson and Zaki Hasan have provided superb programming support for the Protégé and EON projects, respectively.  ... 
doi:10.1055/s-0038-1634543 fatcat:cd23j6vcvra5pff2imleb62bsu

A declarative explanation framework that uses a collection of visualization agents

R D Shankar, S W Tu, M A Musen
1998 Proceedings. AMIA Symposium  
The WOZ framework provides effective explanations for component-based decision-support systems. It represents explanation using explicit models, and employs a collection of visualization agents.  ...  We illustrate the features of WOZ with the help of a component-based medical therapy system.  ...  ACKNOWLEDGEMENTS This work has been supported, in part, by grant LM05708 from the National Library of Medicine, and by a grant from Chiron Coporation.  ... 
pmid:9929290 pmcid:PMC2232258 fatcat:hpouhh5e7zas3jin27dcobille

Towards Semantic Interoperability in a Clinical Trials Management System [chapter]

Ravi D. Shankar, Susana B. Martins, Martin J. O'Connor, David B. Parrish, Amar K. Das
2006 Lecture Notes in Computer Science  
This paper introduces a knowledge-based framework that we are building to support a suite of clinical trial management applications.  ...  Our initiative uses semantic technologies to provide a consistent basis for the applications to interoperate.  ...  This work was supported in part by the Immune Tolerance Network, which is funded by the National Institutes of Health under Grant NO1-AI-15416.  ... 
doi:10.1007/11926078_65 fatcat:gygnpc4derdvbef3vn6hpkhmoe

A framework for group decision support systems: Combining AI tools and OR techniques

Nikos I. Karacapilidis, Costas P. Pappis
1997 European Journal of Operational Research  
Based on this discussion, a framework for an "open", computer-mediated Group Decision Support System is proposed.  ...  Existing frameworks for single-user Decision Support Systems, based on well-established Operations Research methods such as Multicriteria Decision Making techniques, have to be integrated with successful  ...  Acknowledgements: The authors thank the anonymous referees for their useful suggestions and comments on the structure and contents of the paper.  ... 
doi:10.1016/s0377-2217(97)00126-4 fatcat:qebldl6fjvastey4xft5etkdsm

Mediators in the architecture of future information systems

G. Wiederhold
1992 Computer  
For most base data, more than one abstraction must be supported: For the sales manager, the aggregation is by sales region. while aggregation by customer income is appropriate for marketing.  ...  It is not coincidental that Select is the principal operation of relational database management systems, but selected data is still at too fine a level of detail to be useful for decision making.  ...  Acknowledgments This article integrates and extends concepts developed during research into the management of large knowledge bases, primarily supported by DARPA under contract N39-84-C-211.  ... 
doi:10.1109/2.121508 fatcat:qz2fxjjyirey5cztt234gm2boy
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