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The Role Of Circle Of Willis Anatomy Variations In Cardio-embolic Stroke - A Patient-specific Simulation Based Study [article]

Debanjan Mukherjee, Neel D. Jani, Jared Narvid, Shawn C. Shadden
2017 bioRxiv   pre-print
Our simulation framework consists of medical image-driven modeling of patient anatomy including the Circle, 3D blood flow simulation through patient vasculature, embolus transport modeling using a discrete  ...  particle dynamics technique, and a sampling based approach to incorporate parametric variations.  ...  NDJ devised the image-based modeling framework, computed all flow simulations, and contributed to embolus dynamics simulations.  ... 
doi:10.1101/190579 fatcat:5zsb25wsjfgcvhrxfdfseefdzy

Recent Advances in Computational Modeling of Biomechanics and Biorheology of Red Blood Cells in Diabetes

Yixiang Deng, Hung-yu Chang, He Li
2022 Biomimetics  
Diabetes mellitus, a metabolic disease characterized by chronically elevated blood glucose levels, affects about 29 million Americans and more than 422 million adults all over the world.  ...  computational investigations, aiming to provide new inspirations for the development of advanced tools to improve our understanding of the pathogenesis and pathology of T2DM.  ...  Right: Particle-based models for RBCs with equilibrium biconcave (A/V = 1.44) and near-oblate (A/V = 1.04) shapes. (B) Comparison of stretching responses between normal and three T2DM RBC models.  ... 
doi:10.3390/biomimetics7010015 pmid:35076493 pmcid:PMC8788472 fatcat:j2rzdguvbbdy3madqihcdpo5cy

Fourth International Congress on Rheology Brown University, Providence, Rhode Island U.S.A. August 26–30, 1963

Alfred L. Copley, George W. Scott Blair
1963 Biorheology  
Alternative models are proposed, based on recent studies.  ...  On the other hand the model on which the equation is based does not allow for attraction between ,or three dimensional structural organization of, the rod-like aggregates (rouleaux).  ... 
doi:10.3233/bir-1963-1407 fatcat:epqi3475vrhqbosygya5cylgr4

Saturday 25 March 2017

2017 Journal of Medical Radiation Sciences  
There is a relative paucity of evidence supporting chest X-ray reporting by radiographers, especially compared to the substantial evidence base supporting skeletal reporting by radiographers.  ...  Chest X-rays are one of the most frequently performed diagnostic tests worldwide, providing rapid and cost effective assessment across a spectrum of patient pathways.  ...  from the chronic accumulation of pulmonary emboli.  ... 
doi:10.1002/jmrs.1_214 fatcat:5ojthcwnxjccra366mezrimq24


2013 Cerebrovascular Diseases  
In clinical and experimental neurosonology, echo-contrast agents are used not only for transcranial vascular imaging in patients with insufficient bone windows, but they can also be employed for semiquantitive  ...  Recently, we developed a new analysis tool, called multimodal -cal applications.  ...  Object: Sonothrombolysis (ST) has recently been considered an emerging modality for the treatment of stroke.  ... 
doi:10.1159/000351748 pmid:23712294 fatcat:kuw65edukrgkfdsnvwgsbj2r4m


2019 Clinical Neuroradiology  
Conclusion: We report about a rare case of bilateral temporomesial polymicrogyria in a 28-year old female patient as cause for structural epilepsy.  ...  An automated framework for age-specific estimation of brain volume changes relative to a standard population is presented and evaluated.  ...  Using 5F ADAPT combined with BGC a first pass full recanalization rate of 90% could be achieved in red clots and 100% in white clots. In both clot models a 10% rate of distal emboli occurred.  ... 
doi:10.1007/s00062-019-00826-9 fatcat:c6tdsym7jjc5dcduvvz7nxhcj4

Abstracts From the 4th World Stroke Congress

2000 Stroke  
Adenovirus-mediated gene transfer to ependyma may be a promising approach for treatment of brain ischemia.  ...  promising approach for treatment of brain ischemia.  ...  Methods and Results: To provide a framework for this educational model, a mutidisciplinary committee was formed representing medical, nursing and allied health professions.  ... 
doi:10.1161/01.str.31.11.2768 fatcat:xcy3ftmjq5djpfcczcpb4vgkh4

International Academy of Cardiology 18th World Congress on Heart Disease Annual Scientific Sessions 2013. Vancouver, B.C., Canada, July 26-29, 2013

2013 Cardiology  
Acceptance for presentation was based on the average score of all reviewers.  ...  A large number of excellent contributions were received and we thank both contributors and reviewers for their support, interest and effort. Abstract No.  ...  The goal is to provide a framework to help guide clinical decisions related to anticogulation for patients to ensure the best outcome and care.  ... 
doi:10.1159/000354059 pmid:23887240 fatcat:4lu7jkkfcjbjla6g5rx3p242r4

Asia Pacific Stroke Conference 2018. Abstracts of the Annual Conference of the Asia Pacific Stroke Organization (APSO). Jakarta, Indonesia, September 6-9, 2018

2018 Cerebrovascular Diseases  
Methods: The molecular docking simulation was performed to evaluate the inhibition potential of chlorogenic acid for MMP-2, MMP-9, NMDA, nNOS, and iNOS.  ...  Conclusion: This institutional consensus statement provides a review of the evidence for, and implementation of, tPA in acute ischaemic stroke with specific reference to Nepalese health-care system.  ...  The commonest complication is ischemic stroke, either due to mechanical distortion which occludes the deep penetrating arteries or thrombo-emboli from the reduced blood flow.  ... 
doi:10.1159/000493155 pmid:30179873 fatcat:3zpljwglzjapre2lyvinwrkqk4

Abstracts From the 2010 International Stroke Conference: Poster Presentations

2010 Stroke  
The PI team tested methods to reduce falls through evidence based practice. Methods: The team elected to use a 90 day, Plan, Do, Study Act model (P.D.S.A.).  ...  We report here on the adherence to hospital-based quality indicators for stroke, as seen broadly in Colorado over a period of 13 quarters (Q2-2006 through Q2-2009).  ...  We calculated positive and negative predictive values, and accuracy using the cutoff values were 86 %, 90 %, and 88 % for NASCET-DUS; and 68 %, 82 %, and 74 % for PSV.  ... 
doi:10.1161/01.str.0000366115.56266.0a fatcat:ifl42fqawraxxfqufopwld3bua

Analysis of Venous Blood Flow and Deformation in the Calf under External Compression

Ying Wang, Xiao Xu
A 2D finite element model (FEM) with specifically tailored boundary conditions for different muscle components was developed to simulate the deformation of the calf under compression.  ...  In an attempt to improve the 2D FEM, a hyperelastic material model was employed and a finite element based non-rigid registration algorithm was developed to calculate the bulk modulus of the calf tissues  ...  The modelling framework which coupled the structure analysis of soft tissues and CFD modelling of the venous system has a potential to provide an efficient tool for the optimisation of designs of compression  ... 
doi:10.25560/7080 fatcat:6akakaxx7balpb6gq4c6jtdgwm

1. Guidelines on Paediatric Parenteral Nutrition of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN), Supported by the European Society of Paediatric Research (ESPR)

Berthold Koletzko, Olivier Goulet, Joanne Hunt, Kathrin Krohn, Raanan Shamir
2005 Journal of Pediatric Gastroenterology and Nutrition - JPGN  
The aim of the following summary is to provide a framework for the nutrition team member responsible for ordering PN.  ...  Therefore, this chapter cannot provide a fully evidence based recommendation but tries to provide a reasonable framework for the pediatrician who prescribes parenteral vitamins and to point out particular  ...  Recommendations Ranges of reasonable parenteral vitamin supply for infants and children are given in table 2.  ... 
doi:10.1097/01.mpg.0000181841.07090.f4 pmid:16254497 fatcat:ftrjwmmk5jevxd4tshgmvs53gi

The surgeon and the musician☆

Pascal R. Vouhé
2011 European Journal of Cardio-Thoracic Surgery  
Both researchers 1,3 and systematic reviewers 2 have called for a large RCT to address the uncertainty.  ...  This uses engineering tools developed for complex systems (e.g. adaptive modeling and knowledge acquisition frameworks) to more effectively link and strategically direct research projects.  ...  such as thrombo-embolic compli-cations.  ... 
doi:10.1016/j.ejcts.2010.11.046 pmid:21163668 fatcat:fmw7igaahfho7e36ubc2y4fbgy

ECR 2015 Book of Abstracts - A - Postgraduate Educational Programme

2015 Insights into Imaging  
In light of competence-based teaching and learning and continuous professional development a shift towards an outcomes-based model is seen in postgraduate learning.  ...  The proposed model for development of cardiovascular biomarkers resembles that of a new drug or device.  ...  In summary, LDCT-based screening program for lung cancer has a proven survival benefit. Risk models and the use of noninvasive biomarkers may assist with its implementation in the near future.  ... 
doi:10.1007/s13244-015-0386-0 pmid:25708993 pmcid:PMC4349897 fatcat:m7eyvqcwojfpvf3lr5hy6dwjb4

ECR 2016 Book of Abstracts - A - Postgraduate Educational Programme

2016 Insights into Imaging  
In light of competence-based teaching and learning and continuous professional development a shift towards an outcomes-based model is seen in postgraduate learning.  ...  The proposed model for development of cardiovascular biomarkers resembles that of a new drug or device.  ...  In summary, LDCT-based screening program for lung cancer has a proven survival benefit. Risk models and the use of noninvasive biomarkers may assist with its implementation in the near future.  ... 
doi:10.1007/s13244-016-0474-9 pmid:26873353 pmcid:PMC4762839 fatcat:itxslbcacjhh3kixfkcwmdbt44
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