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Separating vascular and neuronal effects of age on fMRI BOLD signals [article]

Kamen A. Tsvetanov, Richard N.A. Henson, James B. Rowe
2020 arXiv   pre-print
A common tool used to investigate neurocognitive ageing is functional magnetic resonance imaging (fMRI).  ...  However, neurovascular ageing is not only a confound in fMRI, but an important feature in its own right, to be assessed alongside measures of neuronal ageing.  ...  Characterization of regional heterogeneity in cerebrovascular reactivity dynamics using novel hypocapnia task and BOLD fMRI.  ... 
arXiv:1912.02899v2 fatcat:tq4mkl776vdzpialwczs5hgama

Physiology of extreme breath-holding [article]

Anthony R. Bain
2016
Respiratory muscle fatigue and pending atelectasis likely determined the capacity of a maximal hyperoxic apnea. Study 3 quantified the cerebral metabolism during apnea.  ...  In elite apnea competitors, the broad objectives of this Thesis were to, a) quantify the impact of peripheral and central chemoreception, and lung volume on the elite dry-land apnea breakpoint, and b)  ...  During the hyperventilation respiratory gases were sampled at the mouth connected to a calibrated gas analyzer (ADInstruments).  ... 
doi:10.14288/1.0305857 fatcat:wa7qdue3ujeerd3e472gdm7zy4

Effects of thyroid hormones on major cardiovascular risk in acute coronary syndromes

A Bayrak, A Bayır, K Uçar Karabulut
2011 Critical Care  
We performed a COX regression analysis to establish whether delays were associated with increased LOS, using age and APACHE as the covariates.  ...  Results show the necessity for cheaper, effi cient and easy-to-use AV systems. References  ...  The aim of this study was to test the eff ects of hypercapnic acidosis on HPV, and the endogenous NO production in hypoxic and hyperoxic lung regions.  ... 
doi:10.1186/cc9421 pmcid:PMC3061631 fatcat:thlzoblo7rb7flmwijycepek4e

Correction: Prevalence, clinical management and risks associated with acute faecal incontinence in the critical care setting: The FIRST questionnaire survey

C Bayón García, R Binks, E De Luca, C Dierkes, A Franci, E Gallart, G Niederalt, D Wyncoll
2011 Critical Care  
We performed a COX regression analysis to establish whether delays were associated with increased LOS, using age and APACHE as the covariates.  ...  Results show the necessity for cheaper, effi cient and easy-to-use AV systems. References  ...  The aim of this study was to test the eff ects of hypercapnic acidosis on HPV, and the endogenous NO production in hypoxic and hyperoxic lung regions.  ... 
doi:10.1186/cc10225 pmcid:PMC4085399 fatcat:qdq3dn7gq5he5bxryuyfshx5py

Typical patterns of expiratory flow and carbon dioxide in mechanically ventilated patients with spontaneous breathing

S. E. Rees, S. Larraza, N. Dey, S. Spadaro, J. B. Brohus, R. W. Winding, C. A. Volta, D. S. Karbing
2016 Journal of clinical monitoring and computing  
A.; Karbing, Dan Stieper  ...  Typical patterns of expiratory flow and carbon dioxide in mechanically ventilated patients with spontaneous breathing Rees, Stephen Edward; Larraza Rico, Sebastián; Dey, N.; Spadaro, S.; Brohus, J.  ...  Conclusion: The QI presented are potentially useful nutritional markers and could implement ICU routine, the presence of a dietitian in the multidisciplinary team can facilitate that task.  ... 
doi:10.1007/s10877-016-9903-z pmid:27344663 fatcat:znxs3iq6vnawdn6se6h7fborja

ESICM LIVES 2016: part two

S. Sivakumar, F. S. Taccone, K. A. Desai, C. Lazaridis, M. Skarzynski, M. Sekhon, W. Henderson, D. Griesdale, L. Chapple, A. Deane, L. Williams, R. Strickland (+2488 others)
2016 Intensive Care Medicine Experimental  
A chi-square test was used to compare proportions of responses between NIs and OIs with a significance p < 0.05.  ...  Fewer make use of preserved pressure reactivity, particularly OIs (vasopressor use 23 % vs. 34 %, p 0.014).  ...  Conclusion: The QI presented are potentially useful nutritional markers and could implement ICU routine, the presence of a dietitian in the multidisciplinary team can facilitate that task.  ... 
doi:10.1186/s40635-016-0099-9 fatcat:rry7hn5zvrgp3o4ukdsslsmd3q

On the regulation of oxygen delivery to the brain in humans

Ryan Leo Hoiland
2018
The same overall reductions in arterial oxygen content elicited a more robust increase in cerebral blood flow and maintenance of cerebral oxygen delivery during hypoxemia than during hemodilution where  ...  Intact, coordinated, and precisely regulated increases in cerebral blood flow are required to compensate for reductions in arterial oxygen content and maintain cerebral oxygen delivery.  ...  Completed across three continents, and within five laboratories I have been influenced by too many people to list here. Some key individuals that deserve recognition are as follows:  ... 
doi:10.14288/1.0371235 fatcat:h6luv2z3rjbzzbs7je34bthmna

38th International Symposium on Intensive Care and Emergency Medicine

2018 Critical Care  
Total cellular oxidative stress was measured using DCFDA Cellular Reactive Oxygen Species (ROS) Detection Assay Kit (Abcam) and mitochondrial superoxide was measured using MitoSOXTM (Life Technology).  ...  Conclusions: The LPS stimulation model could provide a useful approach to study the effect of sepsis on leukocyte metabolism.  ...  When compared to HSEMS targets peer support exceeded national standards. However, there is a clear need for improvement in staff's ability to control and change their working environment.  ... 
doi:10.1186/s13054-018-1973-5 pmid:32831123 fatcat:4iyogy3eazcrrm7zpb4pgauuwm

Annual Meeting of the European Society of Anaesthesiology Munich, Germany, June 9–12, 2007

2007 European Journal of Anaesthesiology  
Conclusion(s): We conclude that nasotracheal RI using the cook's RI kit, with the subcricoid approach is a safe and effective way of securing the airway in patients with anticipated difficult intubation  ...  Results and Discussions: Nasotracheal intubation was successful in 38 patients (95%). Oesophageal intubation occurred in 1 patient in each group.  ...  Cerebrovascular reactivity to CO 2 was expressed as the percentage (%) change in MCAv or CBF (i.e., 1/AVDO 2 ) per mmHg change in PaCO 2 .  ... 
doi:10.1017/s0265021507000798 pmid:17945031 fatcat:infbnitsc5arjow3ewls4v732e