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Sulcal depth in medial ventral temporal cortex predicts the location of a place-selective region in macaques, children, and adults [article]

Vaidehi S Natu, Michael Arcaro, Michael A Barnett, Jesse Gomez, Margaret Livingstone, Kalanit Grill-Spector, Kevin S Weiner
2020 bioRxiv   pre-print
between sulcal depth and place-selectivity in medial VTC across species and age groups.  ...  Our results revealed a strong structural-functional coupling between sulcal depth and place-selectivity across age groups and species in which selectivity was strongest at the deepest sulcal point (the  ...  from 31 independent macaque brains (Seidlitz et al. 2018) ) and a procedure identical to that used for humans. author/funder.  ... 
doi:10.1101/2020.01.27.921346 fatcat:rr2ml7l7cves5brwbnd6ow3c44

A Gyrification Analysis Approach Based on Laplace Beltrami Eigenfunction Level sets

Rosita Shishegar, Fabrizio Pizzagalli, Nellie Georgiou-Karistianis, Gary F. Egan, Neda Jahanshad, Leigh A. Johnston
2021 NeuroImage  
The LB-GI was applied to investigate the cortical maturation profile of the human brain from preschool to early adulthood using the PING database.  ...  An accurate measure of the complexity of patterns of cortical folding or gyrification is necessary for understanding normal brain development and neurodevelopmental disorders.  ...  Brain maturation with age from preschool to early adulthood Fig. 6 . illustrates the significance of cortical folding association with age for LB-GI across the cortex.  ... 
doi:10.1016/j.neuroimage.2021.117751 pmid:33460799 fatcat:dfptzrqjq5eszbxk7dunikfnii

Refinement by integration: aggregated effects of multimodal imaging markers on adult ADHD

Thomas Wolfers, Alberto Llera Arenas, A. Marten H. Onnink, Janneke Dammers, Martine Hoogman, Marcel P. Zwiers, Jan K. Buitelaar, Barbara Franke, Andre F. Marquand, Christian F. Beckmann
2017 Journal of Psychiatry & Neuroscience  
Several markers were also influenced by estimated intelligence, age and/or sex.  ...  Recent methodological developments allow for the integration of information across imaging modalities, potentially yielding a more coherent view regarding the biology underlying the disorder.  ...  Recent methodological developments allow for this integration [17] [18] [19] and have presented novel imaging markers underlying age-dependent brain changes 17, 20 or childhood and adolescent ADHD.  ... 
doi:10.1503/jpn.160240 pmid:28832320 pmcid:PMC5662460 fatcat:c4pri4d7gzacvpqxfclpjolsra

Can Human Amblyopia be Treated in Adulthood?

Andrew T. Astle, Paul V. McGraw, Ben S. Webb
2011 Strabismus  
Amblyopia is a common visual disorder that results in a spatial acuity deficit in the affected eye.  ...  However, in the amblyopic visual system, learned improvements have been shown to generalize to novel tasks.  ...  eye, typically by covering it with a patch, for lengthy periods of time.  ... 
doi:10.3109/09273972.2011.600420 pmid:21870913 pmcid:PMC3433677 fatcat:ozcrldbbq5c3zccmenfcqfkrme

Heritability of individualized cortical network topography [article]

Kevin Michael Anderson, Tian Ge, Ru Kong, Lauren M Patrick, R. Nathan Spreng, Mert R Sabuncu, B.T. Thomas Yeo, Avram Holmes
2020 bioRxiv   pre-print
Here, leveraging a novel non-linear multi-dimensional estimation of heritability, we provide evidence that individual variability in the size and topographic organization of cortical networks are under  ...  Genetic factors had a regionally variable influence on brain organization, such that the heritability of network topography was greatest in prefrontal, precuneus, and posterior parietal cortex.  ...  Of note, we emphasize that our data reflect a snapshot of heritability estimates for a given sample in early adulthood, and that the influence of genetic factors may vary across developmental periods 71  ... 
doi:10.1101/2020.07.30.229427 fatcat:ewywffxrezbzhanp2yvk5opmgy

Opposite development of short- and long-range anterior cingulate pathways in autism

Basilis Zikopoulos, Xuefeng Liu, Justin Tepe, Iris Trutzer, Yohan J. John, Helen Barbas
2018 Acta Neuropathologica  
Our findings provide a timeline for profound changes in axon density and thickness below ACC that affect axon physiology in a direction suggesting bias in short over distant neural communication in autism  ...  We provide novel evidence of changes in the density, size and trajectories of ACC axons in typical postnatal development from childhood through adulthood.  ...  matter regions examined, based on previous maps of the human brain [43, 73] .  ... 
doi:10.1007/s00401-018-1904-1 pmid:30191402 pmcid:PMC6208731 fatcat:2npufjfxlvhvbewwu5qabsmmm4

Page 2614 of Psychological Abstracts Vol. 86, Issue 7 [page]

1999 Psychological Abstracts  
In a second procedure (dis- crimination of 3.0 or 5.6 mg/kg morphine from water), there were no con- sistent differences across strains to the effects of these opioids.  ...  Responding for food reward was maintained by 3 different operant procedures; the first, a 3-component conflict schedule; the second, a multiple fixed-interval 60 s/fixed-ratio 10 (FI60/FR10) schedule:  ... 

Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories

Siobhan S. Pattwell, Conor Liston, Deqiang Jing, Ipe Ninan, Rui R. Yang, Jonathan Witztum, Mitchell H. Murdock, Iva Dincheva, Kevin G. Bath, B. J. Casey, Karl Deisseroth, Francis S. Lee
2016 Nature Communications  
Exploiting this sensitive period of neural development, we modified existing behavioural interventions in an age-specific manner to attenuate adolescent fear memories persistently into adulthood.  ...  Fear can be highly adaptive in promoting survival, yet it can also be detrimental when it persists long after a threat has passed.  ...  Total volume of brain regions were estimated by using Cavalieri estimator and total cell numbers were estimated by Fractionator with counting frame size 25 Â 25 Â 40 mm and sampling grid size 100 Â 100  ... 
doi:10.1038/ncomms11475 pmid:27215672 pmcid:PMC4890178 fatcat:nooh2zh2fjhu7htev4fh6e6bzm

Age-Related EEG Power Reductions Cannot Be Explained by Changes of the Conductivity Distribution in the Head Due to Brain Atrophy

Mingjian He, Feng Liu, Aapo Nummenmaa, Matti Hämäläinen, Bradford C. Dickerson, Patrick L. Purdon
2021 Frontiers in Aging Neuroscience  
To address this ambiguity, we employed EEG forward models to investigate whether brain shrinkage is a major factor for the signal attenuation in the aging brain.  ...  Our results quantify the extent of power reductions from brain shrinkage and pave the way for more accurate inferences about deficient neural activity and circuit integrity based on EEG power reductions  ...  ACKNOWLEDGMENTS The authors would like to thank Matti Stenroos for guidance of using the Helsinki BEM solver for the realistic volume conductor models.  ... 
doi:10.3389/fnagi.2021.632310 pmid:33679380 pmcid:PMC7929986 fatcat:7lof5at77zhwjdyfqgxwghn3tu

Brain Reorganization in Late Adulthood: Rapid Left-to-Right Switch of Handedness Through Memory-Drawing Training [chapter]

Lora T. Likova
2018 Neuroplasticity - Insights of Neural Reorganization  
We were able to address the question of retraining handedness in late adulthood for the first time, well outside the accepted critical period for brain plasticity, through a unique training utilizing the  ...  The unprecedented effect on handedness of the rapid Cognitive-Kinesthetic Drawing Training implies a powerful potential of this training for further rehabilitation domains, such as the rehabilitation of  ...  Tyler for helpful discussions on the manuscript, Kristyo Mineff for assisting with the drawing training, Spero Nicholas for helping with the functional Magnetic Resonance Imaging (fMRI) data collection  ... 
doi:10.5772/intechopen.76317 fatcat:hovfelqvsjervf427w2c4zhpea

The aging mouse brain: cognition, connectivity and calcium

Carola I. Radulescu, Veronika Cerar, Peter Haslehurst, Maksym Kopanitsa, Samuel J. Barnes
2021 Cell Calcium  
Across many systems, we find evidence for prominent age-related dysregulation even before 12 months of age, suggesting that emerging age-related alterations can manifest by late adulthood.  ...  Thus, mice have become a critical tool to better understand how aging impacts the brain.  ...  Acknowledgements We thank Nazanin Doostdar, Joe Airey and Leire Melgosa-Ecenarro for comments on the manuscript and helpful discussions.  ... 
doi:10.1016/j.ceca.2021.102358 pmid:33517250 fatcat:stswk2ht3ncktk2bouvnz56q2u

Reading with Sounds: Sensory Substitution Selectively Activates the Visual Word Form Area in the Blind

Ella Striem-Amit, Laurent Cohen, Stanislas Dehaene, Amir Amedi
2012 Neuron  
in a novel sensory modality, and its plasticity for scripts learned in adulthood.  ...  Further, VWFA recruitment for reading soundscapes emerged after 2 hr of training in a blind adult on a novel script.  ...  We also wish to thank Peter Meijer for fruitful discussions over the years and Lior Reich for useful comments and discussions.  ... 
doi:10.1016/j.neuron.2012.08.026 pmid:23141074 fatcat:onnxartnuvbdljtfnuur2qhy6a

AssemblyNet: A large ensemble of CNNs for 3D Whole Brain MRI Segmentation [article]

Pierrick Coupé, Boris Mansencal, Michaël Clément, Rémi Giraud, Baudouin Denis de Senneville, Vinh-Thong Ta, Vincent Lepetit, José V. Manjon
2019 arXiv   pre-print
In this paper, we present a novel ensemble method based on a large number of CNNs processing different overlapping brain areas.  ...  AssemblyNet introduces sharing of knowledge among neighboring U-Nets, an "amendment" procedure made by the second assembly at higher-resolution to refine the decision taken by the first one, and a final  ...  This is a multisite, longitudinal study of typically developing children from ages newborn through young adulthood conducted by the Brain Development The IXI data used in the preparation of this manuscript  ... 
arXiv:1911.09098v1 fatcat:yq5blqsxbzcenlikojkhphq5oq

Reward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessation

Kathleen A. Garrison, Sarah W. Yip, Iris M. Balodis, Kathleen M. Carroll, Marc N. Potenza, Suchitra Krishnan-Sarin
2017 Drug and Alcohol Dependence  
Background-Tobacco use is often initiated during adolescence and continued into adulthood despite desires to quit.  ...  smokers, although comparison with a developmental control group of adolescent nonsmokers is warranted.  ...  Acknowledgments We thank our research participants for their time and efforts. We thank Theresa Babuscio and Thomas Liss for their assistance with data management.  ... 
doi:10.1016/j.drugalcdep.2017.03.035 pmid:28651213 pmcid:PMC5564393 fatcat:arlzq2eimrf2ffkapgt7g4u4ae

Asthma Induction During Development and Adult Lung Function, Behavior and Brain Gene Expression

Jasmine I. Caulfield, Michael J. Caruso, Rebecca A. Bourne, Nicole R. Chirichella, Laura C. Klein, Timothy Craig, Robert H. Bonneau, Avery August, Sonia A. Cavigelli
2018 Frontiers in Behavioral Neuroscience  
To understand causal mechanisms by which developmental asthma may lead to altered behavior, brain and health trajectories, we developed a mouse model of developmental allergic asthma.  ...  In the current study, we tested for potential long-term effects of developmental asthma on adult lung function and behavior and brain gene expression associated with emotion and stress regulation.  ...  A longitudinal study on humans with asthma determined that childhood asthma severity (at 7 years of age) strongly predicted lung function and persistence of symptoms in adulthood (at 50 years of age;  ... 
doi:10.3389/fnbeh.2018.00188 pmid:30214402 pmcid:PMC6125297 fatcat:oiwhbqbtsvfxzjlyh2nazhcruq
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