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Workflow modeling for virtual processes: an order-preserving process-view approach
2003
Information Systems
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This work describes a novel process-view, i.e., an abstracted process which is derived from a base process to provide process abstraction, for modeling a virtual workflow process. ...
Moreover, this work presents a novel order-preserving approach to derive a process-view from a base process. ...
A typical activity-based approach designs a workflow though a top-down decomposition procedure. ...
doi:10.1016/s0306-4379(02)00028-5
fatcat:gfmsqtjah5ccnag76jozbmiwca
Making processes from best practice frameworks actionable
2009
2009 13th Enterprise Distributed Object Computing Conference Workshops
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A prototype implemented to validate the approach is also described. Abstract-Best-practice frameworks provide guidance for organizing work in business. ...
Best practice frameworks, Business processes, Process-aware Knowledge Repository Best-practice frameworks provide guidance for organizing work in business. ...
Templates offer flexibility while providing the structure necessary for interpretation by the system.
Refinement. We acknowledge the need for process refinement as part of work among people. ...
doi:10.1109/edocw.2009.5332021
dblp:conf/edoc/GraupnerNSB09
fatcat:5hosx6cy4nhbdbbvox3hn7enja
Supporting Continuous Improvement in Care Management with BPM
2012
Software Engineering
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Such a model needs gradual refinements in a continuous improvement perspective, in order to be effective. ...
The proposed approach is about the adoption of a Business Process Modelling technique to "model" all phases and activities of the care management process as developed in Leonardo Project. ...
The next cycle of the care management process, represented by the Galileo Project, will be supported by a novel open-source workflow platform to be customized for care management of chronic diseases which ...
doi:10.5923/j.se.20110102.04
fatcat:uvi3un7kjrd25o5o4e33eujcoq
Tool Support for Dynamic Development Processes
[chapter]
2010
Lecture Notes in Computer Science
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Even in the case of repetitive process fragments, the need for deviations from the workflow definition may occur while a workflow is being enacted. ...
Therefore, we have developed tools for integrating process management and workflow management such that repetitive fragments of the overall development process may be enacted in workflow management systems ...
projects funded by the Deutsche Forschungsgemeinschaft (DFG), namely SUKITS, IMPROVE, and the technology transfer project T6. ...
doi:10.1007/978-3-642-17322-6_27
fatcat:jpt2r3ywhra67l6yhltu7yxgdy
Event-Driven Exception Handling for Software Engineering Processes
[chapter]
2012
Lecture Notes in Business Information Processing
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To alleviate this problem, a dynamic exception handling approach for software engineering processes is presented that incorporates event detection and processing facilities and semantic classification ...
capabilities with a dynamic process-aware information system. ...
Flexibility is improved through the explicit separation of events, exceptions, handling of the exceptions, responsible persons, and the point in the process where a handling is invoked. ...
doi:10.1007/978-3-642-28108-2_40
fatcat:kmshzz7tkrhlbnwzi6r23z7tda
CRISTAL: A practical study in designing systems to cope with change
2014
Information Systems
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This paper uses a study from CERN in Geneva to address these research questions by employing a description-driven approach that is responsive to changes in user requirements and that facilitates dynamic ...
It also identifies lessons that can be learned from adopting such a self-describing description-driven approach in future software development. ...
Acknowledgements The authors wish to thank their respective institutions for the support given during the development of the CRISTAL software. ...
doi:10.1016/j.is.2013.12.009
fatcat:h6uw236dibdfbbjjgbednlzsui
Arbor: Comparative Analysis Workflows for the Tree of Life
2013
PLOS Currents
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Arbor will also be designed to easily and seamlessly expand to include novel analytical tools as they are developed. ...
Arbor will also be designed to easily and seamlessly expand to include novel analytical tools as they are developed. ...
Conclusion We are rapidly approaching a "rough draft" for the Tree of Life. ...
doi:10.1371/currents.tol.099161de5eabdee073fd3d21a44518dc
pmid:23811960
pmcid:PMC3690915
fatcat:pkze4si425efbjnadsfywrquxe
Income/Wf — A Petri Net Based Approach to Workflow Management
[chapter]
1997
Wirtschaftsinformatik '97
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Flexibility of process support is a key requirement for current and future business applications. ...
A technology which is designed to flexibly support various kinds of processes are workflow management systems. ...
Acknowledgement We wish to thank our former colleagues Peter Jaeschke, Volker Sänger, and Thomas Wendel for valuable discussions and many useful comments on earlier versions of this paper as well as for ...
doi:10.1007/978-3-642-57737-6_32
fatcat:7k5p7nbzqnfl3etlx2kwxazgyi
Structure-based molecular modeling in SAR analysis and lead optimization
2021
Computational and Structural Biotechnology Journal
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Their successful application for finding new active molecules for a target is reported by a plethora of studies. ...
However, once a potential lead is identified, lead optimization, with the focus on improving potency, selectivity, or pharmacokinetic parameters of a parent compound, is a much more complex task. ...
Nearly every publication describing a novel activity also proposes a binding mechanism predicted in a docking simulation, often refined by follow-up MD simulations that provide more details on ligand binding ...
doi:10.1016/j.csbj.2021.02.018
pmid:33777339
pmcid:PMC7979990
fatcat:qt6sbtoxfzemdee3yn3tefakpm
3D Printing—A Cutting Edge Technology for Treating Post-Infarction Patients
2021
Life
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applications. 3D printing and additive manufacturing have a great variety of clinical applications targeting anatomy, implants and devices, assisting optimal interventional treatment and post-interventional ...
substantial information on intervention planning in complex cardiovascular diseases, and volumetric medical imaging from CT or MRI can be translated into patient-specific 3D models using advanced post-processing ...
At 10 days of in-vitro incubation, a network of nanofilaments was observed with a size up to 50 nm, with electrical and contractile improved activity. ...
doi:10.3390/life11090910
pmid:34575059
fatcat:isn526itonfxbj6rj3opc7r55u
Computational structure-based drug design: Predicting target flexibility
2018
Wiley Interdisciplinary Reviews. Computational Molecular Science
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An important source for this success is the extraordinary development of faster and more efficient techniques for describing flexibility in 3D structural molecular modeling. ...
The role of molecular modeling in drug design has experienced a significant revamp in the last decade. ...
Pose refinement MD can be used as a post processing tool to validate and/or refine docking results, typically implemented in the drug design lead optimization phase. 139 From MD refinement, the docking ...
doi:10.1002/wcms.1367
fatcat:vahulrtbhnd4vpzjprxxvdqfea
Specification and validation of process constraints for flexible workflows
2005
Information Systems
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The constraint specification framework is based on the concept of "pockets of flexibility" which allows ad hoc changes and/or building of workflows for highly flexible processes. ...
In this paper, we will present a foundation set of constraints for flexible workflow specification. These constraints are intended to provide an appropriate balance between flexibility and control. ...
This evolution may be slight as for process improvements, or drastic as for process innovation or process reengineering. ...
doi:10.1016/j.is.2004.05.002
fatcat:bp4yop6fnbah5a5ep76627ukbm
OpenMS: a flexible open-source software platform for mass spectrometry data analysis
2016
Nature Methods
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We are deeply grateful for the support of the KNIME team, the Proteome Discoverer team, and the Compound Discoverer team. ...
The purpose of the study was to identify novel protein-coding genes, improve evidence for existing gene models and develop a stringent workflow for data analysis. ...
For life science labs using OpenMS, this means fast access to improved algorithms with minimal disruption of existing workflows. ...
doi:10.1038/nmeth.3959
pmid:27575624
fatcat:khqavbue6zepvpbsfzmkwcg6ly
FReDoWS: a method to automate molecular docking simulations with explicit receptor flexibility and snapshots selection
2011
BMC Genomics
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Results: We have developed a Flexible-Receptor Docking Workflow System (FReDoWS) to automate molecular docking simulations using a fully-flexible receptor model. ...
Hence, the process is called structure-based or rational drug design (RDD). In the docking step of RDD the macromolecule or receptor is usually considered a rigid body. ...
Acknowledgements We thank the reviewers for their comments and suggestions which helped to improve the quality of the manuscript and the LAD-PUCRS for CPU time. ...
doi:10.1186/1471-2164-12-s4-s6
pmid:22369186
pmcid:PMC3287589
fatcat:ggodk3lw7zgjrp7dadjzwjzgyq
The view-based approach to dynamic inter-organizational workflow cooperation
2006
Data & Knowledge Engineering
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This paper presents a novel approach to inter-organizational workflow cooperation. ...
Our presented view concept provides a high degree of flexibility for participating organizations, since internal structures of collaborative workflows may be adapted without changes in the inter-organizational ...
Steps for inter-organizational workflow cooperation To meet the requirements we have presented above, we propose a novel approach to interorganizational workflow cooperation. ...
doi:10.1016/j.datak.2005.03.008
fatcat:qn34ecxwzrh2rfkx4jt6y5mrzm
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