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Workflow modeling for virtual processes: an order-preserving process-view approach

Duen-Ren Liu, Minxin Shen
2003 Information Systems  
This work describes a novel process-view, i.e., an abstracted process which is derived from a base process to provide process abstraction, for modeling a virtual workflow process.  ...  Moreover, this work presents a novel order-preserving approach to derive a process-view from a base process.  ...  A typical activity-based approach designs a workflow though a top-down decomposition procedure.  ... 
doi:10.1016/s0306-4379(02)00028-5 fatcat:gfmsqtjah5ccnag76jozbmiwca

Making processes from best practice frameworks actionable

Sven Graupner, Hamid R. Motahari-Nezhad, Sharad Singhal, Sujoy Basu
2009 2009 13th Enterprise Distributed Object Computing Conference Workshops  
A prototype implemented to validate the approach is also described. Abstract-Best-practice frameworks provide guidance for organizing work in business.  ...  Best practice frameworks, Business processes, Process-aware Knowledge Repository Best-practice frameworks provide guidance for organizing work in business.  ...  Templates offer flexibility while providing the structure necessary for interpretation by the system. Refinement. We acknowledge the need for process refinement as part of work among people.  ... 
doi:10.1109/edocw.2009.5332021 dblp:conf/edoc/GraupnerNSB09 fatcat:5hosx6cy4nhbdbbvox3hn7enja

Supporting Continuous Improvement in Care Management with BPM

Mario Bochicchio, Anna Bruno, Antonella Longo
2012 Software Engineering  
Such a model needs gradual refinements in a continuous improvement perspective, in order to be effective.  ...  The proposed approach is about the adoption of a Business Process Modelling technique to "model" all phases and activities of the care management process as developed in Leonardo Project.  ...  The next cycle of the care management process, represented by the Galileo Project, will be supported by a novel open-source workflow platform to be customized for care management of chronic diseases which  ... 
doi:10.5923/ fatcat:uvi3un7kjrd25o5o4e33eujcoq

Tool Support for Dynamic Development Processes [chapter]

Thomas Heer, Markus Heller, Bernhard Westfechtel, René Wörzberger
2010 Lecture Notes in Computer Science  
Even in the case of repetitive process fragments, the need for deviations from the workflow definition may occur while a workflow is being enacted.  ...  Therefore, we have developed tools for integrating process management and workflow management such that repetitive fragments of the overall development process may be enacted in workflow management systems  ...  projects funded by the Deutsche Forschungsgemeinschaft (DFG), namely SUKITS, IMPROVE, and the technology transfer project T6.  ... 
doi:10.1007/978-3-642-17322-6_27 fatcat:jpt2r3ywhra67l6yhltu7yxgdy

Event-Driven Exception Handling for Software Engineering Processes [chapter]

Gregor Grambow, Roy Oberhauser, Manfred Reichert
2012 Lecture Notes in Business Information Processing  
To alleviate this problem, a dynamic exception handling approach for software engineering processes is presented that incorporates event detection and processing facilities and semantic classification  ...  capabilities with a dynamic process-aware information system.  ...  Flexibility is improved through the explicit separation of events, exceptions, handling of the exceptions, responsible persons, and the point in the process where a handling is invoked.  ... 
doi:10.1007/978-3-642-28108-2_40 fatcat:kmshzz7tkrhlbnwzi6r23z7tda

CRISTAL: A practical study in designing systems to cope with change

Andrew Branson, Richard McClatchey, Jean-Marie Le Goff, Jetendr Shamdasani
2014 Information Systems  
This paper uses a study from CERN in Geneva to address these research questions by employing a description-driven approach that is responsive to changes in user requirements and that facilitates dynamic  ...  It also identifies lessons that can be learned from adopting such a self-describing description-driven approach in future software development.  ...  Acknowledgements The authors wish to thank their respective institutions for the support given during the development of the CRISTAL software.  ... 
doi:10.1016/ fatcat:h6uw236dibdfbbjjgbednlzsui

Arbor: Comparative Analysis Workflows for the Tree of Life

Luke J. Harmon, Jeffrey Baumes, Charles Hughes, Jorge Soberon, Chelsea D Specht, Wesley Turner, Curtis Lisle, Robert W. Thacker
2013 PLOS Currents  
Arbor will also be designed to easily and seamlessly expand to include novel analytical tools as they are developed.  ...  Arbor will also be designed to easily and seamlessly expand to include novel analytical tools as they are developed.  ...  Conclusion We are rapidly approaching a "rough draft" for the Tree of Life.  ... 
doi:10.1371/currents.tol.099161de5eabdee073fd3d21a44518dc pmid:23811960 pmcid:PMC3690915 fatcat:pkze4si425efbjnadsfywrquxe

Income/Wf — A Petri Net Based Approach to Workflow Management [chapter]

Andreas Oberweis, Roland Schätzle, Wolffried Stucky, Wolfgang Weitz, Gabriele Zimmermann
1997 Wirtschaftsinformatik '97  
Flexibility of process support is a key requirement for current and future business applications.  ...  A technology which is designed to flexibly support various kinds of processes are workflow management systems.  ...  Acknowledgement We wish to thank our former colleagues Peter Jaeschke, Volker Sänger, and Thomas Wendel for valuable discussions and many useful comments on earlier versions of this paper as well as for  ... 
doi:10.1007/978-3-642-57737-6_32 fatcat:7k5p7nbzqnfl3etlx2kwxazgyi

Structure-based molecular modeling in SAR analysis and lead optimization

Veronika Temml, Zsofia Kutil
2021 Computational and Structural Biotechnology Journal  
Their successful application for finding new active molecules for a target is reported by a plethora of studies.  ...  However, once a potential lead is identified, lead optimization, with the focus on improving potency, selectivity, or pharmacokinetic parameters of a parent compound, is a much more complex task.  ...  Nearly every publication describing a novel activity also proposes a binding mechanism predicted in a docking simulation, often refined by follow-up MD simulations that provide more details on ligand binding  ... 
doi:10.1016/j.csbj.2021.02.018 pmid:33777339 pmcid:PMC7979990 fatcat:qt6sbtoxfzemdee3yn3tefakpm

3D Printing—A Cutting Edge Technology for Treating Post-Infarction Patients

Daniel Cernica, Imre Benedek, Stefania Polexa, Cosmin Tolescu, Theodora Benedek
2021 Life  
applications. 3D printing and additive manufacturing have a great variety of clinical applications targeting anatomy, implants and devices, assisting optimal interventional treatment and post-interventional  ...  substantial information on intervention planning in complex cardiovascular diseases, and volumetric medical imaging from CT or MRI can be translated into patient-specific 3D models using advanced post-processing  ...  At 10 days of in-vitro incubation, a network of nanofilaments was observed with a size up to 50 nm, with electrical and contractile improved activity.  ... 
doi:10.3390/life11090910 pmid:34575059 fatcat:isn526itonfxbj6rj3opc7r55u

Computational structure-based drug design: Predicting target flexibility

Jelisa Iglesias, Suwipa Saen-oon, Robert Soliva, Victor Guallar
2018 Wiley Interdisciplinary Reviews. Computational Molecular Science  
An important source for this success is the extraordinary development of faster and more efficient techniques for describing flexibility in 3D structural molecular modeling.  ...  The role of molecular modeling in drug design has experienced a significant revamp in the last decade.  ...  Pose refinement MD can be used as a post processing tool to validate and/or refine docking results, typically implemented in the drug design lead optimization phase. 139 From MD refinement, the docking  ... 
doi:10.1002/wcms.1367 fatcat:vahulrtbhnd4vpzjprxxvdqfea

Specification and validation of process constraints for flexible workflows

Shazia W. Sadiq, Maria E. Orlowska, Wasim Sadiq
2005 Information Systems  
The constraint specification framework is based on the concept of "pockets of flexibility" which allows ad hoc changes and/or building of workflows for highly flexible processes.  ...  In this paper, we will present a foundation set of constraints for flexible workflow specification. These constraints are intended to provide an appropriate balance between flexibility and control.  ...  This evolution may be slight as for process improvements, or drastic as for process innovation or process reengineering.  ... 
doi:10.1016/ fatcat:bp4yop6fnbah5a5ep76627ukbm

OpenMS: a flexible open-source software platform for mass spectrometry data analysis

Hannes L Röst, Timo Sachsenberg, Stephan Aiche, Chris Bielow, Hendrik Weisser, Fabian Aicheler, Sandro Andreotti, Hans-Christian Ehrlich, Petra Gutenbrunner, Erhan Kenar, Xiao Liang, Sven Nahnsen (+15 others)
2016 Nature Methods  
We are deeply grateful for the support of the KNIME team, the Proteome Discoverer team, and the Compound Discoverer team.  ...  The purpose of the study was to identify novel protein-coding genes, improve evidence for existing gene models and develop a stringent workflow for data analysis.  ...  For life science labs using OpenMS, this means fast access to improved algorithms with minimal disruption of existing workflows.  ... 
doi:10.1038/nmeth.3959 pmid:27575624 fatcat:khqavbue6zepvpbsfzmkwcg6ly

FReDoWS: a method to automate molecular docking simulations with explicit receptor flexibility and snapshots selection

Karina S Machado, Evelyn K Schroeder, Duncan D Ruiz, Elisângela ML Cohen, Osmar Norberto de Souza
2011 BMC Genomics  
Results: We have developed a Flexible-Receptor Docking Workflow System (FReDoWS) to automate molecular docking simulations using a fully-flexible receptor model.  ...  Hence, the process is called structure-based or rational drug design (RDD). In the docking step of RDD the macromolecule or receptor is usually considered a rigid body.  ...  Acknowledgements We thank the reviewers for their comments and suggestions which helped to improve the quality of the manuscript and the LAD-PUCRS for CPU time.  ... 
doi:10.1186/1471-2164-12-s4-s6 pmid:22369186 pmcid:PMC3287589 fatcat:ggodk3lw7zgjrp7dadjzwjzgyq

The view-based approach to dynamic inter-organizational workflow cooperation

Issam Chebbi, Schahram Dustdar, Samir Tata
2006 Data & Knowledge Engineering  
This paper presents a novel approach to inter-organizational workflow cooperation.  ...  Our presented view concept provides a high degree of flexibility for participating organizations, since internal structures of collaborative workflows may be adapted without changes in the inter-organizational  ...  Steps for inter-organizational workflow cooperation To meet the requirements we have presented above, we propose a novel approach to interorganizational workflow cooperation.  ... 
doi:10.1016/j.datak.2005.03.008 fatcat:qn34ecxwzrh2rfkx4jt6y5mrzm
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