A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Filters
A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts
2016
JAMIA Journal of the American Medical Informatics Association
Preserved Fulltext
Objective: Our objective was to develop an approach for selecting combinatorial markers of pathology from diverse clinical data types. ...
To derive optimal markers for cyst classification from the preoperative clinical and radiological data, we developed a statistical approach for combining any number of categorical, dichotomous, or continuous-valued ...
of clinical data, and select composite markers of cyst type and grade from a large cohort of patients with surgically resected pancreatic cysts. ...
doi:10.1093/jamia/ocw069
pmid:27330075
pmcid:PMC5201184
fatcat:zkgav5xf3zch7oxsrc7nsr6pey
Radiomics for the Diagnosis and Differentiation of Pancreatic Cystic Lesions
2020
Diagnostics
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Although these studies are limited by the use of retrospective design, single center data, and small sample sizes, radiomic features in combination with clinical data appear to be superior to the current ...
There is a need for multicenter prospective studies to elucidate the role of radiomics in the management of PCLs. ...
As evidenced in large surgical databases, 17-25% of patients who undergo surgical resection for a presumed mucinous lesion ultimately have a benign cyst [10, 11] . ...
doi:10.3390/diagnostics10070505
pmid:32708348
pmcid:PMC7399814
fatcat:kjirioji5fblph33pv4f2eicaa
Natural language processing for the development of a clinical registry: a validation study in intraductal papillary mucinous neoplasms
2010
HPB
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
We seek to develop a novel NLP system that could be applied in our clinical network to develop a functional registry of IPMN patients. ...
Conclusions: Natural language processing is a reliable and accurate method for identifying selected patient cohorts and may facilitate the identification and follow-up of patients with IPMN. ...
Conflicts of interest None declared. ...
doi:10.1111/j.1477-2574.2010.00235.x
pmid:21083794
pmcid:PMC3003479
fatcat:ziuwwul4ubb75lpypwfoj7i3qq
Clinical Perspective on Proteomic and Glycomic Biomarkers for Diagnosis, Prognosis, and Prediction of Pancreatic Cancer
2021
International Journal of Molecular Sciences
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
However, for reasons discussed in this review, the validation and clinical translation of these candidate markers has not been successful. ...
Consequently, there has been a change of mindset from initial efforts to identify new unimarkers into the current hypothesis that a combination of biomarkers better suits a diagnostic or prognostic panel ...
Acknowledgments: The authors wish to thank J.W. ...
doi:10.3390/ijms22052655
pmid:33800786
fatcat:mdo4cjrrkfdvzgyatgfdjpnkgu
Combining radiomic features with a miRNA classifier may improve prediction of malignant pathology for pancreatic intraductal papillary mucinous neoplasms
2016
OncoTarget
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
Using a retrospective cohort of 38 surgically-resected, pathologically-confirmed IPMNs (20 benign; 18 malignant) with preoperative computed tomography (CT) images and matched plasma-based 'miRNA genomic ...
Consensus guidelines for IPMN management rely on standard radiologic features to predict pathology, but they lack accuracy. ...
ACKNOWLEDGMENTS The authors wish to thank the following individuals for their contributions: Christina Georgeades, Rebecca Bohinc, Kimberly Quinn, Michelle Fournier, Sean Yoder, Danny Yakoub, Alberto Garcia ...
doi:10.18632/oncotarget.11768
pmid:27589689
pmcid:PMC5349874
fatcat:dln6zqpfxvgzreotf6kie6vtxu
Biomarkers and Strategy to Detect Pre-Invasive and Early Pancreatic Cancer: State of the Field and the Impact of the EDRN
2020
Cancer Epidemiology, Biomarkers and Prevention
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
A compelling strategy to broaden the use of surveillance for PDAC is to incorporate molecular biomarkers in combination with clinical analysis and imaging tools. ...
Patients afflicted with pancreatic ductal adenocarcinoma (PDAC) face a dismal prognosis, but headway could be made if physicians could identify the disease earlier. ...
Haab); Alliance of Glycobiologists for Cancer Detection, U01 CA226158 (to B.B. Haab and R.E. Brand); U01 CA200468, U01 CA196403, R01 CA218004, and P50 CA221707 (to A. Maitra); U01 CA200466 (to R.E. ...
doi:10.1158/1055-9965.epi-20-0161
pmid:32532830
pmcid:PMC7710622
fatcat:jnncvcr4zrgp5b7vhoqo3n6qsa
Multi-Omic Biomarkers as Potential Tools for the Characterisation of Pancreatic Cystic Lesions and Cancer: Innovative Patient Data Integration
2021
Cancers
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Successful integration of different 'omics' data could aid in the identification of a novel integrated biomarker profile for the risk stratification of patients with PCLs and PC. ...
This review highlights the importance of biological markers in the context of PCLs and PC, with a focus on 'omics'-related work. ...
Acknowledgments: We are deeply grateful to the Meath Foundation for supporting our research. Figure 2 was created with BioRender.com. ...
doi:10.3390/cancers13040769
pmid:33673153
pmcid:PMC7918773
fatcat:qwvv5qnixrgtrd2enmuwbcv66a
Endoscopic Ultrasound and Related Technologies for the Diagnosis and Treatment of Pancreatic Disease - Research Gaps and Opportunities
2017
Pancreas
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Although some advocate for surgical resection without biopsy, sampling these masses to determine the exact diagnosis remains important because a significant minority of these patients do not have pancreatic ...
Common themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders ...
We thank Ms Joy Merusi of the University of Pittsburgh and Ms Mary Allen of Scientific Consulting Group, Inc, for logistic and organizational assistance. ...
doi:10.1097/mpa.0000000000000936
pmid:28926412
pmcid:PMC5645254
fatcat:oqz7dna3mbabniq33qzzte3tuy
Abstracts
2013
HPB
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Here we deliver novel drugs selectively to pancreatic cancers using sigma-2 ligands and targeting a survival/apoptosis pathway. ...
for complex pancreatic resections and reconstructions to be performed through a minimally invasive approach. ...
A stepwise approach to achieve resectability avoids the long-term sequelae of OLT. ...
doi:10.1111/hpb.12048
pmid:23383868
pmcid:PMC3575878
fatcat:d33jq2zluvfypjexhqqchspzcq
Abstracts
2009
HPB
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Methods: A retrospective review of all patients undergoing hepatic resection for HCC from 1/1990 to 1/2008 was conducted. ...
The purpose of this study was to determine the outcome of patients undergoing a second hepatic resection for recurrent HCC at a Western center and to identify prognostic variables. ...
Tq as a novel inhibitor of proinflammatory pathways provides a promising strategy that combines anti-inflammatory and proapoptotic modes of action.
21 A proteomic based platform for marker discovery ...
doi:10.1111/j.1477-2574.2008.00035.x
fatcat:3xvrc3duzjfzbiartcgkmyvxga
New Era of Endoscopic Ultrasound-Guided Tissue Acquisition: Next-Generation Sequencing by Endoscopic Ultrasound-Guided Sampling for Pancreatic Cancer
2019
Journal of Clinical Medicine
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Pancreatic cancer is a lethal cancer with an increasing incidence. Despite improvements in chemotherapy, patients with pancreatic cancer continue to face poor prognoses. ...
Due to advancements in next-generation sequencing (NGS) technologies, multiple parallel sequencing can be applied to EUS-TA samples. ...
Consequently, EUS-TA is expected to play a complementary role in the clinical management of pancreatic cysts. ...
doi:10.3390/jcm8081173
pmid:31387310
pmcid:PMC6723875
fatcat:xerdfs3jfjav5fd6ztnprhrchy
Management of pancreatic ductal adenocarcinoma (PDAC): Progress in the past decade and challenges for the future
2019
Cancer Reports and Reviews
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Large cohorts of patients with pancreatic cysts are being followed to improve knowledge of the natural history and risks of progression in these pre-cancerous lesions. ...
Although there is a large window for surgical resection before progression from preneoplastic lesions to invasive cancer, the rate of advanced PDAC (stage III or IV) at diagnosis is more than 80%. ...
doi:10.15761/crr.1000184
fatcat:caxwd3eqovbb7isoo4tst3xuky
Abstracts
2012
HPB
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
of neoadjuvant therapy without systemic progression. 3D-CASP was particularly helpful in patient with borderline resectable pancreatic cancer to reduce risk for a margin-positive resection. ...
We investigated the impact of lean body mass among patients who underwent neoadjuvant therapy and surgical resection for pancreatic cancer (PC). ...
We conducted a retrospective chart review of 40 RADP performed by a single surgeon (A. Y.) between 2006 and 2010. ...
doi:10.1111/j.1477-2574.2012.00437.x
pmid:22356212
pmcid:PMC4503268
fatcat:bkprfwgc7zakpcrwfnkj26v6tm
Concurrent Sessions Orals
2013
HPB
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Conclusion: MELD has a better performance over the CTP score in determination of priorities for organ allocation. ...
Aim of the study to compare the CTP scores and MELD score for 3, 6 months survival in cirrhotic patients waiting for liver transplant. ...
Acknowledgements: The work was supported by the National Natural Science Foundation of China (81070354). ...
doi:10.1111/hpb.12092
fatcat:qhlbq4pqqzhj3kvpcmbvnztd6u
Summary of the 44th Annual Pancreas Club Meeting Proceedings
2011
Journal of Gastrointestinal Surgery
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Ten posters each day were chosen for presentation as part of the professor rounds portion of the formal poster viewing program. Summaries of the oral presentations are provided. ...
Discussion The program consisted of 42 oral presentations (Table 1 ) and 61 abstracts chosen for poster presentation. ...
They concluded that evaluation of both EGFR and EGF may select patients who best respond to targeted therapies with EGFR inhibitors. ( 18 ) "HuR Status Is a Powerful Clinical Marker for Resected Pancreatic ...
doi:10.1007/s11605-011-1449-2
pmid:21336498
fatcat:jpo2wvc3afhsfcqbh6xjngjtxa
« Previous
Showing results 1 — 15 out of 862 results