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The Tie2 present in the membrane of glioma cells could serve as a target for novel therapies for gliomas. ... We have established an in vivo co-culture model that will enable us to examine the contribution of endothelial cells to tumor growth both in the subcutaneous and orthotopic model. ... For our animal experiments, U251 glioma cells were implanted subcutaneously in female nude mice. ...doi:10.1215/15228517-2006-020 fatcat:mmlprjrhe5egznipgrd737ugkq
Blood or muscle can be used as a DNA source for the genetic identification of recently deceased persons. If the post mortem interval increases, bones and teeth are used. ... DNA extraction from 5 mg of fingernails from 7 volunteers using 1 h cell lysis in a standard buffer and a DNA purification on QIAamp DNA mini kit columns allowed to acquire a mean quantity of 100 ng DNA ... Acknowledgements: the authors thank Christophe Bonny, Peter Clarke and Jean-François Brunet for helpful discussion. This work is supported by the CTI grant #8909.1 PFLS-LS. ...doi:10.1080/15459620802177484 pmid:18569516 fatcat:bjf22zzr3beljomywn7ooqn44e
are commonly used. ... Recently, a capillary gel electrophoresisbased PCR ribotyping assay has been developed that significantly reduces the hands-on time required for C. difficile PCR ribotyping. ... In vivo efficacy was evaluated against a CTX-M-15-like-producing E. coli strain using a lethal peritonitis sepsis model in neutropenic ICR mice. Survival was monitored for seven days after infection. ...doi:10.1111/j.1469-0691.2010.03238.x pmid:20412063 pmcid:PMC7130035 fatcat:o6vuxo77pvbdhijpoxf72yrio4
Established human astrocytoma cell lines were used to generate stable cell lines that were grown as subcutaneous xenograft models in NODSCID mice and studied for their growth and vascularity. ... We further characterized the anticancer efficacy of this new virus in vivo using an athymic mouse subcutaneous tumor model and a brain tumor model (U87dEGFR cells). ... In conclusion, the use of ANP for DBSG compares favorably with standard radiation therapy, which offers less than a 10% survival at 2 years for newly diagnosed DBSG. TP-03. ...doi:10.1215/s1152851704100148 fatcat:iphxxorg6bgpdpuc7aba6fftb4
These cells were then monitored for growth in vitro and in immunocompromised mice. ... into animals. ... MOTEXAFIN GADOLIN IUM (MGD) DELAYS NEUROCOGNITIVE PROGRESSION IN PATIENTS WITH BRAIN METASTASES FROM LUNG CANCER: RESULTS OF A RANDOMIZED PHASE III TRIAL ...doi:10.1093/neuonc/4.4.308 fatcat:4evmjim2rnaujgaxgwvz3etqcq
Mamo, A. Armatys, J.P.C. Mamo Obstetrics and Gynaecology Unit, Gozo General Hospital, Gozo ... Severe soft tissue swelling on the medial side of the ankle joint, and/or difficult or failed reduction of the fracture should prompt the surgeon that underlying soft tissue injury might be associated ... The two-staged procedure is preferred as it allows significant soft-tissue swelling to subside. ...fatcat:ttgoo7ldkrenrh3ryrraxihape