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A new perspective on the competent programmer hypothesis through the reproduction of bugs with repeated mutations [article]

Eike Stein, Steffen Herbold, Fabian Trautsch, Jens Grabowski
2021 arXiv   pre-print
Within this article, we provide a new perspective on the competent programmer hypothesis and its relation to mutation testing.  ...  Because this implies that bugs should usually manifest through small variations of the correct code, the competent programmer hypothesis is one of the fundamental assumptions of mutation testing.  ...  This gives us a new perspective on the competent programmer hypothesis than prior work that, e.g., only considered how many tokens are changed by bugs or manually compared mutations with bugs.  ... 
arXiv:2104.02517v1 fatcat:j3vsquj3urd2bgqamdrittso7u

Wolbachia: endosymbiont of onchocercid nematodes and their vectors

Ranju Ravindran Santhakumari Manoj, Maria Stefania Latrofa, Sara Epis, Domenico Otranto
2021 Parasites & Vectors  
This offers the development of new approaches for the control of a variety of vector-borne diseases. Graphic Abstract  ...  Methods This review details the molecular data of Wolbachia and its effect on host biology, immunity, ecology and evolution, reproduction, endosymbiont-based treatment and control strategies exploited  ...  The authors acknowledge the use of BioRender software for the preparation of Fig. 2 .  ... 
doi:10.1186/s13071-021-04742-1 pmid:33962669 pmcid:PMC8105934 fatcat:h44cz5cyljh6bejeqry4xivmui

Challenges on applying genetic improvement in JavaScript using a high-performance computer

Fábio de Almeida Farzat, Márcio de Oliveira Barros, Guilherme Horta Travassos
2018 Journal of Software Engineering Research and Development  
It describes our experience on performing a study with fifteen projects submitted to genetic improvement with the use of a supercomputer.  ...  Genetic Improvement is an area of Search Based Software Engineering that aims to apply evolutionary computing operators to the software source code to improve it according to one or more quality metrics  ...  Funding This research was developed with the support of the Núcleo Avançado de Computação de Alto Desempenho (NACAD) of COPPE/UFRJ. CAPES and CNPq also supported this research. Prof.  ... 
doi:10.1186/s40411-018-0056-2 fatcat:wzjklcgc6bd4pcnuzro556iogi

Nabokov, Teleology, and Insect Mimicry

Victoria N. Alexander
2002 Nabokov Studies  
Acknowledgements This essay is based on research conducted at the Santa Fe Institute and published as a working paper, one hundred copies of which were circulated within the scientific community for comment  ...  Although aberrant forms might be stabilized through selection, neutral mechanisms allow the mutation process to diffuse through a wide range of genotypes with various wildcard configurations.  ...  Elsewhere Nabokov discusses the reproductive advantage of other forms of disruptive coloring, "A bird comes and wonders for a second. Is it two bugs? Where is the head? Which side is which?  ... 
doi:10.1353/nab.2010.0004 fatcat:ithviy4rfzc4nlrn6svg2mbgbi

No PAIN, No Gain? The Utility of PArallel Fault INjections

Stefan Winter, Oliver Schwahn, Roberto Natella, Neeraj Suri, Domenico Cotroneo
2015 2015 IEEE/ACM 37th IEEE International Conference on Software Engineering  
Depending on the complexity of this operational environment, the complexity of the software under test, and the number and type of faults, a thorough SFI assessment can entail (a) numerous experiments  ...  While PArallel fault INjections (PAIN) yield higher experiment throughput, they are based on an implicit assumption of non-interference among the simultaneously executing experiments.  ...  We dedicate this paper to the memory of Fabian Vogt, whose work on an earlier version of the PAIN framework has greatly influenced its current architecture.  ... 
doi:10.1109/icse.2015.67 dblp:conf/icse/WinterSNSC15 fatcat:nemih2265zbzti7xhho3e4on4m

Selecting fault revealing mutants

Thierry Titcheu Chekam, Mike Papadakis, Tegawendé F. Bissyandé, Yves Le Traon, Koushik Sen
2019 Empirical Software Engineering  
Mutant selection refers to the problem of choosing, among a large number of mutants, the (few) ones that should be used by the testers.  ...  higher average percentage of revealed faults with a median difference between 4% and 9% (from the random mutant orderings).  ...  , and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.  ... 
doi:10.1007/s10664-019-09778-7 fatcat:umfqknxrifcenoctbe5dkajj4a

Genetic Programming III - Darwinian Invention and Problem Solving

Peter Nordin
1999 Evolutionary Computation  
Special thanks goes to our reviewers, who stuck with us through a major reorganization of the book and provided insightful and useful comments.  ...  Acknowledgments We would like to acknowledge the help of our editor, Denise Penrose, and that of Edward Wade and Emilia Thiuri, at Morgan Kaufmann Publishers.  ...  If a gene resulted in a reduction of reproduction (e.g., through delayed fertility or some instinctive form of infanticide), then its frequency would decrease as competing genes-ones that reproduced at  ... 
doi:10.1162/evco.1999.7.4.451 fatcat:27732t6mfvgt7mzpbvkrv6wcqm

Age-related variation in energy expenditure in a long-lived bird within the envelope of an energy ceiling

Kyle H. Elliott, Maryline Le Vaillant, Akiko Kato, Anthony J. Gaston, Yan Ropert-Coudert, James F. Hare, John R. Speakman, Donald Croll, Daniel Ardia
2013 Journal of Animal Ecology  
Many studies have observed an increase in reproductive success with age followed by a reduction at the end of life, but fewer studies have examined the proximate mechanisms, which provide a context for  ...  Alternatively, both young and very old animals may lack the ability to maintain high levels of energy expenditure (the -constraint‖ hypothesis), leading to reduced reproductive success.  ...  Specifically, modern molecular gerontology focuses on the discovery of "immortality" genes (genes in which mutation induces a modification in longevity) and several research programmes work towards the  ... 
doi:10.1111/1365-2656.12126 pmid:23991724 fatcat:g35bf5np75d3flua5tqcgrh4wa

Crystal ball - 2009

2009 Environmental Microbiology Reports  
In this feature, leading researchers in the field of environmental microbiology speculate on the technical and conceptual developments that will drive innovative research and open new vistas over the next  ...  In other words, the urgent questions in environmental microbiology are known, the methods and technologies are largely available, but the culture and art of retrieving and dealing with A geochemist colleague  ...  Acknowledgements We would like to extend special thanks to the Agouron Institute, the C-MORE, and the School of Ocean and Earth Science at the University of Hawaii at Mā noa.  ... 
doi:10.1111/j.1758-2229.2008.00010.x pmid:23765716 fatcat:a2h7akkx5zg7pntlrwpwjj6rh4

Towards the safe use of modern biotechnology: Report on the 7th International Symposium on the Biosafety of Genetically Modified Organisms held in Beijing (China) October 10-16, 2002

Ervin Balázs
2003 Environmental Biosafety Research  
SPEAKERS Crop-to crop gene flow: dispersal of transgenes during field tests and commercialization Baltazar Baltazar Pioneer Hi-Bred International, Mexico Gene flow from crops to wild relatives in Asia:  ...  INTRODUCTION The scientific programme of the Symposium has been introduced by a session on "New science for enhanced biosafety".  ...  Ow proposed a strategy that permits the sequential and repeated delivery of new DNA to the genomic target, as might be expected if a transgenic plant line were to be improved over time through the sequential  ... 
doi:10.1051/ebr:2003003 fatcat:bqryzgisf5hptjirxsqyafnh7u

Breaking out of the black box: a new approach to robot perception

Martin C. Martin, Howie M. Choset, Douglas W. Gage, Pushkin Kachroo, Mikhail A. Kourjanski, Marten J. de Vries
1999 Mobile Robots XIII and Intelligent Transportation Systems  
To illustrate this idea, I propose to create a visual obstacle avoidance system on the Uranus mobile robot.  ...  Genetic Programming is used to combine these into a new depth estimate. The system learns by predicting both sonar readings and the next image.  ...  The three most common are areas of low texture (e.g. a flat grey wall); fence post errors, where a feature repeats through the environment (e.g. a fence or row of file cabinets); and the halo effect when  ... 
doi:10.1117/12.335691 dblp:conf/mr/Martin98 fatcat:r4e2fzewffeujoz5hka6l57ooq

Agronomic Linked Data (AgroLD): a Knowledge-based System to Enable Integrative Biology in Agronomy [article]

Aravind Venkatesan, Gildas Tagny Ngompe, Nordine El Hassouni, Imene Chentli, Valentin Guignon, Clement Jonquet, Manuel Ruiz, Pierre Larmande
2018 biorxiv/medrxiv   pre-print
We expect the resolution of these questions to facilitate the formulation of new scientific hypotheses to be validated with a knowledge-oriented approach.  ...  This increase, in conjunction with the heterogeneity and variability of the data, presents a major challenge to adopt an integrative research approach.  ...  A version exists today in our lab with maize data produced from projects of A. Charcosset's GQMS team and theirs partners. Perspectives are to use it for tomato, wheat and poplar data.  ... 
doi:10.1101/325423 fatcat:57xxtwu3uvc55jflrjmycsw2ja

Abstracts of the 20th College of Medicine Research Dissemination Conference

Linda A. Sande, Levison S. Chiwaula, Patrick Kambewa, Don P. Mathanga
2017 Malawi Medical Journal  
We evaluated the dose/concentration A7 A8 A6 Results We included a subset of participants who continued on TS prophylaxis (n=34) or stopped prophylaxis (n=27).  ...  The aim was to evaluate the cardiac safety of DHA-PPQ with a normal dose (< 26 mg/kg) and high dose PPQ (≥ 26 mg/kg) in Malawian children.  ...  a hypothesis.  ... 
doi:10.4314/mmj.v28i4.9 fatcat:t3h4tkmc6jdixokgdmd32ebzni

Poster Abstracts

2014 Integrative and Comparative Biology  
For example, the use of song by male passerine birds changes across season in accordance with reproductive state.  ...  Jingle bells were painted with either a shiny or matte finish of the same color.  ...  These issues may be due to the abundance of mutations acquired through treatment with mutagen, working with a single locus, or small sample sizes.  ... 
doi:10.1093/icb/icu009 fatcat:bwtfvcxovnfbtaglzx7irgcu7m

Cognitive Constructivism and the Epistemic Significance of Sharp Statistical Hypotheses in Natural Sciences [article]

J.M. Stern
2020 arXiv   pre-print
We believe that this alternative perspective, complementary to the one ofered by decision theory, can provide powerful insights and make pertinent contributions in the context of scientific research.  ...  This metaphor has proven to be very useful, leading the development of Bayesian statistics since its XX-th century revival, rooted on the work of de Finetti, Savage and others.  ...  Instead, a good scientist should always confront a sharp hypothesis with a competing sharp hypotheses, making the test a fair game.  ... 
arXiv:1006.5471v8 fatcat:v375ybolz5bkbe6ordmjnnulhi
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