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A new baseline for retinal vessel segmentation: Numerical identification and correction of methodological inconsistencies affecting 100+ papers [article]

György Kovács, Attila Fazekas
2021 arXiv   pre-print
Including more than 100 papers in the study, we performed a detailed numerical analysis of the coherence of the published performance scores.  ...  In the last 15 years, the segmentation of vessels in retinal images has become an intensively researched problem in medical imaging, with hundreds of algorithms published.  ...  Acknowledgments György Kovács would like to thank the support of the initiative 1LU-51P-4E. On behalf of Attila Fazekas, this work was supported by the construction EFOP-3.6.3-VEKOP-16-2017-00002.  ... 
arXiv:2111.03853v1 fatcat:37yzkla2ljgovgoxr3mkrbrydq

Human Treelike Tubular Structure Segmentation: A Comprehensive Review and Future Perspectives [article]

Hao Li, Zeyu Tang, Yang Nan, Guang Yang
2022 arXiv   pre-print
Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels.  ...  In this survey, we aim to provide a comprehensive review of currently publicly available datasets, segmentation algorithms, and evaluation metrics.  ...  Hybrid UNet: A hybrid UNet based approach for retinal vessel segmentation is proposed in [78] , consisting of a multi-task segmentation network and a fusion network.  ... 
arXiv:2207.11203v1 fatcat:dhij4yezovh3hesjwzrk3yswea

Exudates as Landmarks Identified through FCM Clustering in Retinal Images

Hadi Hamad, Tahreer Dwickat, Domenico Tegolo, Cesare Valenti
2020 Applied Sciences  
The aim of this work was to develop a method for the automatic identification of exudates, using an unsupervised clustering approach.  ...  Our methodology was optimized, and verified and the parameters were fine-tuned in order to define both suitable values and to produce a more accurate segmentation.  ...  Khwaira for his valuable time in preparing the manual ground truth. We would also like to thank the teams for providing the publicly available datasets: DIARETDB0/1, IDRID, and e-optha.  ... 
doi:10.3390/app11010142 fatcat:4lm5uzjlavdwtfzvgvustue7lm

Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward

Jessica Alber, Danielle Goldfarb, Louisa I. Thompson, Edmund Arthur, Kimberly Hernandez, Derrick Cheng, Delia Cabrera DeBuc, Francesca Cordeiro, Leonardo Provetti-Cunha, Jurre den Haan, Gregory P. Van Stavern, Stephen P. Salloway (+2 others)
2020 Alzheimer's & Dementia  
The last decade has seen a substantial increase in research focused on the identification, development, and validation of diagnostic and prognostic retinal biomarkers for Alzheimer's disease (AD).  ...  Sensitive retinal biomarkers may be advantageous because they are cost and time efficient, non-invasive, and present a minimal degree of patient risk and a high degree of accessibility.  ...  Beta-amyloid protein deposits in the retina Though animal models show promise in identifying retinal A𝛽 in vivo, research on identification of retinal A𝛽 in humans is limited and inconsistent.  ... 
doi:10.1002/alz.12006 pmid:31914225 fatcat:ppo5brfednc5xjt5ocqbn6wzea

Glaucoma Detection Using Image Processing and Supervised Learning for Classification

Shubham Joshi, B. Partibane, Wesam Atef Hatamleh, Hussam Tarazi, Chandra Shekhar Yadav, Daniel Krah, Bhagyaveni M.A
2022 Journal of Healthcare Engineering  
For this study, the primary goal is to estimate the potential of the image analysis model for the early identification and diagnosis of glaucoma, as well as for the evaluation of ocular disorders.  ...  An ensemble-based deep learning model for the identification and diagnosis of glaucoma is in its early stages now.  ...  Prior to segmentation, one should first conduct a set of procedures aimed at addressing problems of noise, poor lighting, and retinal structures that affect the processing of the image.  ... 
doi:10.1155/2022/2988262 pmid:35273784 pmcid:PMC8904131 fatcat:3evzldvw2jg4lazy6653fhj6yy

Clopidogrel used in combination with aspirin compared with aspirin alone in the treatment of non-ST-segment-elevation acute coronary syndromes: a systematic review and economic evaluation

C Main, S Palmer, S Griffin, L Jones, V Orton, M Sculpher, R Henderson, C Sudlow, N Hawkins, R Riemsma
2004 Health Technology Assessment  
Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.  ...  Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it.  ...  Of these, 100 papers were used as background articles for the review. The majority of the other excluded articles were non-systematic reviews, commentaries and letters to the editor.  ... 
doi:10.3310/hta8400 pmid:15461878 fatcat:wwqholk6ffcpvfrtpacl3fitmm

Interventions for central serous chorioretinopathy: a network meta-analysis

Mahsa Salehi, Adam S Wenick, Hua Andrew Law, Jennifer R Evans, Peter Gehlbach
2015 The Cochrane library  
Interventions for central serous chorioretinopathy: a network metaanalysis. The Cochrane database of systematic reviews (12). CD011841.  ...  Interventions for central serous chorioretinopathy: a network meta-analysis.  ...  FA and ICGA are imaging techniques that allow for the identification of abnormal leakage of fluid from the choroidal and retinal vessels as well as through the RPE layer.  ... 
doi:10.1002/14651858.cd011841.pub2 pmid:26691378 pmcid:PMC5030073 fatcat:d7xweugsbrhc7jba42netbvzbi

Towards a Connected Mobile Cataract Screening System: A Future Approach

Wan Mimi Diyana Wan Zaki, Haliza Abdul Mutalib, Laily Azyan Ramlan, Aini Hussain, Aouache Mustapha
2022 Journal of Imaging  
This paper aims to review the development and limitations of published methods for cataract detection and grading using different imaging modalities.  ...  Therefore, the use of digital images from a smartphone as the future of cataract screening tools could be a practical and helpful solution for ophthalmologists, especially in rural areas with limited healthcare  ...  They achieved a classification accuracy of 100% for normal eyes, 85.7% for eyes with immature cataracts, and 60% for eyes with mature cataracts.  ... 
doi:10.3390/jimaging8020041 pmid:35200743 pmcid:PMC8879609 fatcat:wvbyppxl3ncbzfjyfquohugsmu

Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT

Philip Hykin, A Toby Prevost, Sobha Sivaprasad, Joana C Vasconcelos, Caroline Murphy, Joanna Kelly, Jayashree Ramu, Abualbishr Alshreef, Laura Flight, Rebekah Pennington, Barry Hounsome, Ellen Lever (+7 others)
2021 Health Technology Assessment  
The primary outcome was an increase in the best corrected visual acuity letter score from baseline to 100 weeks in the trial eye.  ...  The objective was to compare the clinical effectiveness and cost-effectiveness of three intravitreal antivascular endothelial growth factor agents for the management of macula oedema due to central retinal  ...  , for their invaluable support and advice throughout the study.  ... 
doi:10.3310/hta25380 pmid:34132192 fatcat:ufzhgptmkjeiznni45e4hfxrxe

Visual function and dysfunction in early and late age-related maculopathy

R.E. Hogg, U. Chakravarthy
2006 Progress in retinal and eye research  
Despite progress in this area, we emphasise the need for longitudinal studies designed in light of developments in disease classification and retinal imaging, which would ensure the correct classification  ...  It has devastating effects on quality of life and independence and is becoming a major public health concern.  ...  Acknowledgement This work was supported by a grant from The Health Foundation.  ... 
doi:10.1016/j.preteyeres.2005.11.002 pmid:16580242 fatcat:txg2b4ncebhldpmdu5y3uwiabe

Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy

Gianni Virgili, Francesca Menchini, Giovanni Casazza, Ruth Hogg, Radha R Das, Xue Wang, Manuele Michelessi
2015 The Cochrane library  
Since this review was conceived, the role of OCT has changed and has become a key ingredient of decision-making at all levels of ophthalmic care in this field.  ...  The median central retinal thickness cut-off we selected for data extraction was 250 µm (range 230 µm to 300 µm).  ...  Search methods for identification of studies  ... 
doi:10.1002/14651858.cd008081.pub3 pmid:25564068 pmcid:PMC4438571 fatcat:wlukrdvmwjd6nbx6kf3yfaidcy

Different lasers and techniques for proliferative diabetic retinopathy

Tanya Moutray, Jennifer R Evans, Noemi Lois, David J Armstrong, Tunde Peto, Augusto Azuara-Blanco
2018 The Cochrane library  
Proliferative DR (PDR) is a sight-threatening complication of DR and is characterised by the development of abnormal new vessels in the retina, optic nerve head or anterior segment of the eye.  ...  Over the years, there have been modifications of the technique and introduction of new laser technologies.  ...  primary outcome of our review and therefore was not appropriate to omit from the summary of findings table. • We added in the new outcome of regression of PDR (see Types of outcome measures) • We removed  ... 
doi:10.1002/14651858.cd012314.pub2 pmid:29543992 pmcid:PMC6494342 fatcat:etqogwterfhwvbhyvn7lumlhma

Accuracy of fundus autofluorescence imaging for the diagnosis and monitoring of retinal conditions: a systematic review

Geoff K Frampton, Neelam Kalita, Liz Payne, Jill Colquitt, Emma Loveman
2016 Health Technology Assessment  
Searches covered 1990 to November 2014 and were limited to the English language.Review methodsReferences were screened for relevance using prespecified inclusion criteria to capture a broad range of retinal  ...  use in clinical practice, it is unclear whether or not FAF imaging is accurate, and whether or not it is applied and interpreted consistently for the diagnosis and/or monitoring of retinal conditions.  ...  Eye Hospital and John Radcliffe Hospital; Professor Andrew Lotery, Consultant Ophthalmologist, Faculty of Medicine, University of Southampton and Southampton University Hospitals NHS Foundation Trust;  ... 
doi:10.3310/hta20310 pmid:27115052 fatcat:ukgvzgz4jnfr3lsyfwpvcilfiy

Twins Eye Study in Tasmania (TEST): Rationale and Methodology to Recruit and Examine Twins

David A. Mackey, Jane R. MacKinnon, Shayne A. Brown, Lisa S. Kearns, Jonathan B. Ruddle, Paul G. Sanfilippo, Cong Sun, Christopher J. Hammond, Terri L. Young, Nicholas G. Martin, Alex W. Hewitt
2009 Twin Research and Human Genetics  
AbstractVisual impairment is a leading cause of morbidity and poor quality of life in our community.  ...  Twin siblings provide a unique opportunity in biology to discover genes associated with numerous eye diseases and ocular biometry.  ...  DAM is a recipient of the Pfizer Australia Senior Research Fellowship.  ... 
doi:10.1375/twin.12.5.441 pmid:19803772 pmcid:PMC3855231 fatcat:muqq36tgtrekpfokffdq7blqnm

Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy

S. Scott Whitmore, Elliott H. Sohn, Kathleen R. Chirco, Arlene V. Drack, Edwin M. Stone, Budd A. Tucker, Robert F. Mullins
2015 Progress in retinal and eye research  
Finally, we present a hypothesis for the pathogenesis of early AMD and consider the implications of this model on the development of new therapies.  ...  on the retinal pigment epithelium, Bruch's membrane and the photoreceptor cells.  ...  Acknowledgments The authors wish to thank the Iowa Lions Eye Bank and the many eye donors and their families who have thoughtfully donated their tissues to the benefit of everyone affected by eye diseases  ... 
doi:10.1016/j.preteyeres.2014.11.005 pmid:25486088 pmcid:PMC4339497 fatcat:vhtkdq5qrvbcdl2jasd2ixpwgi
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