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A longitudinal human phantom reliability study of multi-center T1-weighted, DTI, and resting state fMRI data

Colin Hawco, Joseph D. Viviano, Sofia Chavez, Erin W. Dickie, Navona Calarco, Peter Kochunov, Miklos Argyelan, Jessica A. Turner, Anil K. Malhotra, Robert W. Buchanan, Aristotle N. Voineskos
2018 Psychiatry Research : Neuroimaging  
Here, we sought to establish the utility of a clustering algorithm as an alternative to more traditional intra-class correlation coefficient approaches in a longitudinal multi-center human phantom study  ...  With increasing interest in data-driven approaches in psychiatric and neurologic brain imaging studies, our findings provide a framework for multi-center analytic approaches aiming to identify subgroups  ...  This provides strong support for the integration of data in multi-center studies, and supports the use of hierarchical clustering to identify individuals across imaging metrics.  ... 
doi:10.1016/j.pscychresns.2018.06.004 pmid:29945740 pmcid:PMC6482446 fatcat:zbfre24gfvclppt2t6ipwmyrwa

Developing a Neuroimaging Biomarker for Amyotrophic Lateral Sclerosis: Multi-Center Data Sharing and the Road to a "Global Cohort"

Robert Steinbach, Nayana Gaur, Beatrice Stubendorff, Otto W. Witte, Julian Grosskreutz
2018 Frontiers in Neurology  
This review will use the example of the Neuroimaging Society in ALS (NiSALS) to discuss the set-up of a multi-center data sharing ecosystem and the flow of information between various stakeholders.  ...  Multi-center transnational collaborations are needed to address these methodological limitations and achieve representation of rare phenotypes.  ...  , while particular higher field strengths and enlarged acquisition resolutions decreased inter-center variability (22) .  ... 
doi:10.3389/fneur.2018.01055 pmid:30564187 pmcid:PMC6288231 fatcat:bnh7ty4ygbdytbew6rj7xdmd44

The NIH MRI study of normal brain development

Alan C. Evans
2006 NeuroImage  
In a subset, we acquired T1/T2 relaxometry, diffusion tensor imaging, single-voxel proton spectroscopy and spectroscopic imaging.  ...  Using a uniform acquisition protocol, data were collected at six Pediatric Study Centers and consolidated at a Data Coordinating Center.  ...  Diffusion tensor imaging (DTI) data are analyzed at a DTI Processing Center, National Institute of Child Health and Development (NICHD) NIH (DPC).  ... 
doi:10.1016/j.neuroimage.2005.09.068 pmid:16376577 fatcat:q7k25iz34rgbpadjdbqcgp7bpy

Pulmonary Emphysema Subtypes on Computed Tomography: The MESA COPD Study

Benjamin M. Smith, John H.M. Austin, John D. Newell, Belinda M. D'Souza, Anna Rozenshtein, Eric A. Hoffman, Firas Ahmed, R. Graham Barr
2014 American Journal of Medicine  
Methods-The Multi-Ethnic Study of Atherosclerosis COPD Study recruited smokers with COPD and controls age 50-79 years with ≥10 pack-years. Participants underwent CT following a standardized protocol.  ...  Results-Twenty-seven percent of 318 smokers had emphysema on CT. Inter-rater reliability of emphysema subtype was substantial (K:0.70).  ...  Acknowledgments FUNDING SOURCES NIH/NHLBI R01-HL093081, R01-HL077612, R01-HL075476, and N01-HC95159-HC95169. Fonds de la recherche en santé Québec.  ... 
doi:10.1016/j.amjmed.2013.09.020 pmid:24384106 pmcid:PMC3882898 fatcat:744sa4vygrgnxajmh3rei7t4fa

Quantification of Regional Interstitial Lung Disease from CT-derived Fractional Tissue Volume

Cuneyt Yilmaz, Snehal S. Watharkar, Alberto Diaz de Leon, Christine K. Garcia, Nova C. Patel, Kirk G. Jordan, Connie C.W. Hsia
2011 Academic Radiology  
There is a need for standardized imaging biomarkers to quantify regional disease, maximize diagnostic yield, and facilitate multi-center comparisons.  ...  The next step would be to study a larger series, examine reproducibility and follow longitudinal changes in correlation with clinical and functional indices.  ...  Acknowledgments Supported by: National Heart, Lung, and Blood Institute grants R03 HL097010 (CY), R01 HL093096 (CKG), a pilot award (to CCH) by the North and Central Texas Clinical and Translational Science  ... 
doi:10.1016/j.acra.2011.03.004 pmid:21596593 pmcid:PMC3128646 fatcat:bcmxgbyqq5ffdguics4vitxkva

Repetitive Transcranial Magnetic Stimulation with Resting-State Network Targeting for Treatment-Resistant Depression in Traumatic Brain Injury: A Randomized, Controlled, Double-Blinded Pilot Study

Shan H. Siddiqi, Nicholas T. Trapp, Carl D. Hacker, Timothy O. Laumann, Sridhar Kandala, Xin Hong, Ludwig Trillo, Pashtun Shahim, Eric C. Leuthardt, Alexandre R. Carter, David L. Brody
2019 Journal of Neurotrauma  
Here, we investigate the use of rTMS targeted with individualized resting-state network mapping (RSNM) of dorsal attention network (DAN) and default mode network (DMN) in subjects with treatment-resistant  ...  Treatment was targeted to the dorsolateral prefrontal cluster with maximal difference between DAN and DMN correlations based on resting-state functional magnetic resonance imaging with individualized RSNM  ...  The magnitude of inter-individual variability appeared to exceed the intrinsic test-retest reliability of the scans; targets identified using two back-to-back scanning sessions were centered 0.9-8.3 mm  ... 
doi:10.1089/neu.2018.5889 pmid:30381997 pmcid:PMC6909726 fatcat:ctvgecjwenhkjnvlqrjebjzhpu

A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins

Brandon S. Nichols, Christine E. Schindler, Jonathon Q. Brown, Lee G. Wilke, Christine S. Mulvey, Marlee S. Krieger, Jennifer Gallagher, Joseph Geradts, Rachel A. Greenup, Jesko A. Von Windheim, Nirmala Ramanujam, Christof Markus Aegerter
2015 PLoS ONE  
Specifically detailed in this work is the performance and clinical validation of a research-grade intra-operative tool for margin assessment based on diffuse optical spectroscopy.  ...  A raster-scanning mechanism was developed to achieve sub-pixel resolution and was found to be optimally performed at an upsample factor of 8, affording 0.75mm spatially resolved diffuse reflectance images  ...  Following orientation, the raster-scanning procedure was initiated and the diffuse reflectance spectra were collected across the visible spectrum (λ = 420-700nm).  ... 
doi:10.1371/journal.pone.0127525 pmid:26076123 pmcid:PMC4468201 fatcat:mc6lxceg6jhlzfaqlksw3p2tqy

Multi-Steps Registration Protocol for Multimodal MR Images of Hip Skeletal Muscles in a Longitudinal Study

Lucia Fontana, Alfonso Mastropietro, Elisa Scalco, Denis Peruzzo, Elena Beretta, Sandra Strazzer, Filippo Arrigoni, Giovanna Rizzo
2020 Applied Sciences  
The hips of 6 subjects were scanned, in a multimodal protocol, at 2 different time points by a 3 Tesla scanner; the proposed multi-step registration pipeline is based on rigid and elastic transformations  ...  This paper aims at proposing a reliable registration protocol and evaluating its accuracy in a longitudinal study.  ...  In conclusion, the present study is a first attempt to propose and assess a reliable pipeline for the automated intra-session and longitudinal muscle MR images registration, in a multimodal study.  ... 
doi:10.3390/app10217823 fatcat:jgalf36uwrdvfabzst7vfyuas4

A Review of Current Challenges and Case Study Toward Optimizing Micro-Computed X-ray Tomography of Carbon Fabric Composites

Armin Rashidi, Tina Olfatbakhsh, Bryn Crawford, Abbas S. Milani
2020 Materials  
This article, through a review of the state of the art, followed by an example case study on Micro-computed tomography (CT) analysis of low X-ray absorptive dry and prepreg carbon woven fabric composites  ...  X-ray computed tomography provides qualitative and quantitative structural and compositional information for a broad range of materials.  ...  Segmentation is a challenging task mostly due to (1) wide imaging variability resulting from different imaging modalities, scanning protocols, and scanners parameters; (2) large intra- and inter-sample  ... 
doi:10.3390/ma13163606 pmid:32824047 pmcid:PMC7475927 fatcat:p7qt3vhah5cwxc5z2zz5a5rrlm

Simulation study of an X-ray diffraction system for breast tumordetection

F. Marticke, G. Montémont, C. Paulus, O. Michel, J.I. Mars, L. Verger
2017 Nuclear Instruments and Methods in Physics Research Section A : Accelerators, Spectrometers, Detectors and Associated Equipment  
The influence 26 of incident spectrum maximum energy was also studied. The required dose re-27 mained very low with any of the incident spectra tested.  ...  This system allows depth-imaging in one go but needs 17 an x,y-direction scan to image the region conventional mammography identified 18 as suspect.  ...  The impact of variability of breast thickness 679 and tissue scattering signatures should also be studied.  ... 
doi:10.1016/j.nima.2017.04.026 fatcat:cocrs3wocrfxdlxdglkmdqjo44

MRI utility in patients with non-traumatic metatarsalgia: A tertiary musculoskeletal center observational study

Mohamed Ragab Nouh, Ehab Ali Abd El-Gawad, Samir Mahmoud Abdulsalam
2015 The Egyptian Journal of Radiology and Nuclear Medicine  
Patients and methods: The study included 125 patients (46 males and 79 female) with a mean age 38.8 years (age range 7-74 years) presented with forefoot pain.  ...  Patients with history of a clear recent forefoot trauma, gross osteo-articular deformities and previous forefoot surgery were excluded.  ...  Short-axis scans of the forefoot on T1W (a) and PD fat-suppressed image (b) showing fibular-sided subcutaneous multi-lobulated fatty lesions wrapping around its both dorsal and plantar aspects.  ... 
doi:10.1016/j.ejrnm.2015.08.004 fatcat:z4slvm5gfvb6xdwhqb3qgi7aum

Dissociating Statistically-Determined Alzheimer's Disease/Vascular Dementia Neuropsychological Syndromes Using White and Gray Neuroradiological Parameters

Catherine C. Price, Jared J. Tanner, Ilona M. Schmalfuss, Babette Brumback, Kenneth M. Heilman, David J. Libon
2015 Journal of Alzheimer's Disease  
brain imaging, investigate between group differences in gray and white matter regions of interest.  ...  Methods-An analysis of neuropsychological functioning was obtained from dementia patients clinically diagnosed with AD/VaD characterized with significant leukoaraiosis (LA) and/or lacunes where a k-means  ...  Study Funding/Disclosures: This study was partially supported by NIH (NINDS K23NS60660 and ROI NS082386; NINR ROI NR014181; CP) and Alzheimer's Association IIRG0627542 (DJL).  ... 
doi:10.3233/jad-150407 pmid:26402109 pmcid:PMC4724866 fatcat:5yxfvoghbvdttp4sgdkbffxuqm

Progression of Regional Microstructural Degeneration in Parkinson's Disease: A Multicenter Diffusion Tensor Imaging Study

Yu Zhang, I-Wei Wu, Duygu Tosun, Eric Foster, Norbert Schuff, Karl Herholz
2016 PLoS ONE  
Automated image processing included an intra-subject registration of all time points and an inter-subjects registration to a brain atlas.  ...  This study aimed to identify the utility of diffusion tensor imaging (DTI) in measuring the regional distribution of abnormal microstructural progression in patients with Parkinson's disease who were enrolled  ...  Lastly, the study demonstrates the practicability of multi-center diffusion imaging in PD. Several limitations of our study should be mentioned.  ... 
doi:10.1371/journal.pone.0165540 pmid:27798653 pmcid:PMC5087900 fatcat:hlcxksn6h5bw7fs7sfee254js4

Variable echo time imaging for detecting the short T2* components of the sciatic nerve: a validation study

Paolo Florent Felisaz, Eugenio Belatti, Xeni Deligianni, Niels Bergsland, Francesco Santini, Matteo Paoletti, Francesca Solazzo, Giancarlo Germani, Andrea Cortese, Elisa Vegezzi, Oliver Bieri, Stefano Bastianello (+1 others)
2020 Magnetic Resonance Materials in Physics, Biology and Medicine  
Good-to-excellent repeatability and reproducibility were found for geometry of ROIs (Dice indices: intra-rater 0.68-0.7; inter-rater 0.70-0.72) and the related aT2* measures (intra-inter reader ICC 0.95  ...  The aim of this study was to develop and validate an MRI protocol based on a variable echo time (vTE) sensitive to the short T2* components of the sciatic nerve. 15 healthy subjects (M/F: 9/6; age: 21-  ...  Further studies correlating imaging and pathological findings in a spectrum of inflammatory, vascular degenerative diseases of the sciatic nerve are warranted.  ... 
doi:10.1007/s10334-020-00886-w pmid:32964300 fatcat:65irw4q5szbmvfgpsju4sme624

COMPULS: design of a multicenter phenotypic, cognitive, genetic, and magnetic resonance imaging study in children with compulsive syndromes

Jilly Naaijen, Saskia de Ruiter, Marcel P. Zwiers, Jeffrey C. Glennon, Sarah Durston, David J. Lythgoe, Steven C. R. Williams, Tobias Banaschewski, Daniel Brandeis, Barbara Franke, Jan K. Buitelaar
2016 BMC Psychiatry  
Methods: The COMPULS study is a multi-center study designed to investigate the relationship between the traits compulsivity, impulsivity, and, to a lesser extent, addictive behaviour within and across  ...  Discussion: The COMPULS study will offer the unique opportunity to investigate several key aspects of compulsivity across a large cohort of ADHD, ASD and OCD patients.  ...  Acknowledgements The authors would like to thank The TACTICS Consortium Group, consisting of Jan Buitelaar, Saskia de Ruiter, Jilly  ... 
doi:10.1186/s12888-016-1072-6 pmid:27782808 pmcid:PMC5080712 fatcat:6ufp3eotaje6bdznpdwnpyh2nu
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