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However, the results of these methods are not always accurate enough. We show how to extend one of these segmentation methods, active shape models (ASM) so that user interaction can be incorporated. ... Supervised segmentation methods in which a model of the shape of an object and its gray-level appearance is used to segment new images have become popular techniques in medical image segmentation. ... Maas for producing the manual segmentations used in this study. ...doi:10.1117/12.480165 dblp:conf/miip/GinnekenBLV03 fatcat:5q3r6xxszrbmvlz3boq7k7vpqy
Calcineurin antagonists such as tacrolimus and ascomycins (e.g., pimecrolimus) act by inhibiting the activation of the nuclear factor for activated T cells (NFAT). ... In addition to the literature review, we report a novel class of nonantibiotic 14-member macrocycle with anti-inflammatory and immunomodulatory effects.Conclusions. ... This approach is opening a broad field of skin disease treatments that have minimal side effects (Table 1) . ...doi:10.1155/2012/563709 pmid:23258954 pmcid:PMC3507315 fatcat:qynvprqt4jctbgtlkrz5ftcc34