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Magnetic resonance-based morphometry: a window into structural plasticity of the brain

Arne May, Christian Gaser
2006 Current Opinion in Neurology  
Recent findings Next to the detection of structural differences in grey and white matter in a number of brain diseases, a very important recent finding of magnetic resonance-based morphometry is the discovery  ...  Consequently, magnetic resonance morphometry promises to be a powerful method to study disease states of the brain and to track the effects of novel therapies.  ...  While early imaging studies of the brain provided a qualitative description of normal brain morphology and its deviations in disease states, more recently developed MR-based methods allow a quantitative  ... 
doi:10.1097/01.wco.0000236622.91495.21 pmid:16914981 fatcat:hgfbh73imnbp7emtfyskjkhzcm

Diffusion-tensor magnetic resonance imaging in children with language impairment

Jinna Kim, Yong Wook Kim, Chang-il Park, Eun Sook Park, Hyang-Hee Kim, Seung-Koo Lee, Dong Ik Kim
2006 NeuroReport  
We evaluated the integrity of the white matter tract using di¡usion-tensor magnetic resonance imaging in children with language impairments who exhibited a structurally normal brain on conventional magnetic  ...  revealed on conventional magnetic resonance images.  ...  Although some quantitative morphometric analyses of MR images suggested subtle structural abnormalities of the specific brain regions, most children presenting the mildest form of LI have normal brain  ... 
doi:10.1097/01.wnr.0000230516.86090.67 pmid:16951569 fatcat:ae7t3s6m4rf3llkz3ypbudz6g4

Basic principles of MRI and morphometry studies of human brain development

David N. Kennedy, Nikos Makris, Martha R. Herbert, Tsutomu Takahashi, Verne S. Caviness
2002 Developmental Science  
Magnetic resonance imaging has undergone dramatic development in the past years.  ...  This paper will cover the classes of information that are readily available in the MR image, the mechanisms for extracting quantitative results, and a sample of the application of these types of methods  ...  Acknowledgements This work was supported in part by grants NS34189 as part of the Human Brain Project, NS20489, NS02126, the Don and Linda Carter Foundation, the Fairway Trust, and the Giovanni Armenise-Harvard  ... 
doi:10.1111/1467-7687.00366 fatcat:sh2o5w65trbz5h77hrvdwzpafe

A longitudinal study of brain morphometrics using serial magnetic resonance imaging analysis in a canine model of aging

Min-Ying Su, P. Dwight Tapp, Long Vu, Ya-Fang Chen, Yong Chu, Bruce Muggenburg, Jr-Yuan Chiou, Changqing Chen, Jun Wang, Christian Bracco, Elizabeth Head
2005 Progress in Neuro-psychopharmacology and Biological Psychiatry  
Annual magnetic resonance imaging (MRI) was performed to acquire images from the whole brain, and the longitudinal changes in cortical atrophy, ventricular enlargement and development of brain lesions  ...  The MR images of each dog obtained in 4 studies were co-registered using SPM.  ...  Annual magnetic resonance imaging (MRI) was performed to acquire images from the whole brain, and the longitudinal changes in cortical atrophy, ventricular enlargement and development of brain lesions  ... 
doi:10.1016/j.pnpbp.2004.12.005 pmid:15795047 fatcat:cfduiexhnzalpbkkkrblyw4u7a

Quantitative Structural Brain Magnetic Resonance Imaging Analyses: Methodological Overview and Application to Rett Syndrome

Tadashi Shiohama, Keita Tsujimura
2022 Frontiers in Neuroscience  
Recent advances in data analysis programs have led to significant progress in the quantitative analysis of anatomical structural magnetic resonance imaging (MRI) and diffusion-weighted MRI tractography  ...  This mini-review focuses on the methodologies and attempts employed to study Rett syndrome using quantitative structural brain MRI analyses, including voxel- and surface-based morphometry and diffusion-weighted  ...  ACKNOWLEDGMENTS We are grateful to Emi Takahashi and Jacob Levman for supervising our research.  ... 
doi:10.3389/fnins.2022.835964 pmid:35450016 pmcid:PMC9016334 fatcat:zscbnjb3njg4vh4fj2rqdst6ji

MRI-based morphometric analysis of typical and atypical brain development

David N. Kennedy, Christian Haselgrove, Sean McInerney
2003 Mental Retardation and Developmental Disabilities Research Reviews  
Rapid advancement in image acquisition methods, image analysis tools and interpretation of morphometric results make the study of in vivo anatomic analysis both challenging and rewarding.  ...  This paper will briefly cover the methods of morphometric analysis that available for neuroanatomic analysis, and tour some sample results from a prototype retrospective database of neuroanatomic volumetric  ...  ACKNOWLEDGEMENTS This work was supported in part by grants NS34189 as part of the Human Brain Project, NS20489, NS02126, the Don and Linda Carter Foundation, the Fairway Trust, and the Giovanni Armenise  ... 
doi:10.1002/mrdd.10075 pmid:12953294 fatcat:6n24qx5zrnhfbmfyhegu75nwmm

Page 1260 of The Journal of Neuroscience Vol. 27, Issue 6 [page]

2007 The Journal of Neuroscience  
Pfefferbaum A, Mathalon DH, Sullivan EV, Rawles JM, Zipursky RB, Lim KO (1994) A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood.  ...  Hazlett HC, Poe M, Gerig G, Smith RG, Provenzale J, Ross A, Gilmore J, Piven J (2005) Magnetic resonance imaging and head circumference study of brain size in autism: birth through age 2 years.  ... 

Modeling Brain Growth and Development [chapter]

N. Sadeghi, G. Gerig, J.H. Gilmore
2015 Brain Mapping  
Magnetic resonance imaging (MRI) has provided us with an unprecedented view of the brain in vivo.  ...  Brain Growth as observed in anatomical MRI Magnetic resonance imaging (MRI) is appropriate for longitudinal pediatric studies since it does not use ionizing radiation and enables safe noninvasive scanning  ...  Acknowledgments This research was supported by NIH grants: R01 MH070890 (JHG, GG), Conte Center MH064065 (JHG,GG), and National Alliance for Medical Image Computing (NA-MIC) U54 EB005149 (GG).  ... 
doi:10.1016/b978-0-12-397025-1.00314-6 fatcat:iebucnloq5db5e3bxosfuux2re

Methods of MRI-based structural imaging in the aging monkey

N. Makris, D.N. Kennedy, D.L. Boriel, D.L. Rosene
2010 Methods  
For instance, for any particular voxel in the cerebrum we can obtain structural T1-, diffusion-and magnetization transfer-magnetic resonance imaging (MRI) based information.  ...  The capability of studying the living brain non-invasively with MRI opens up a new window in structural-functional and anatomic-clinical relationships allowing the integration of information derived from  ...  Conclusion This review has addressed quantitative neuroimaging studies of the aging monkey brain, the integration of different imaging modalities in brain structure analysis, and the correlation of behaviors  ... 
doi:10.1016/j.ymeth.2009.06.007 pmid:19577648 pmcid:PMC3774020 fatcat:g5zp353a65cvjdxpcnpspxsohe

Correlation Between Corpus Callosum Shape and Craniometric Measurements According to Mri Data

Olga Boiagina, Oleksandr Stepanenko, Anastasiia Lebedieva
2021 Brain: Broad Research in Artificial Intelligence and Neuroscience  
Magnetic resonance tomographic scanner Magnetom C was used for obtaining MRI images.  ...  Morphometric study was conducted using RadiAnt Dicom Viewer software on MR scans performed in the sagittal area in T1- and T2-weighted images modes.  ...  Magnetic resonance tomographic scanner Magnetom C was used for obtaining MRI images.  ... 
doi:10.18662/brain/12.3/216 fatcat:be4l4vvxwnfjxhmgv2zrfcflfi

Genetic dissection of the mouse CNS using magnetic resonance microscopy

Alexandra Badea, G Allan Johnson, Robert W Williams
2009 Current Opinion in Neurology  
We review results of a systematic genetic analysis of MRM data using as a case study a family of wellcharacterized lines of mice.  ...  Here we review (1) MRM capabilities and image segmentation methods; (2) heritability of brain variation; (3) covariation of the sizes of brain regions; and (4) correlations between MRM and classical histological  ...  CIVM members are also supported by NIH grant (NCRR P41 RR005959/ NCI U24 CA092656), while GeneNetwork is also supported by NIAAA U24AA13513 and U01AA13499, a Human Brain Project funded jointly by NIDA,  ... 
doi:10.1097/wco.0b013e32832d9b86 pmid:19542887 pmcid:PMC2734144 fatcat:xqdhhz32yfdhfc4t5wxxumfpc4

Compact Magnetic Resonance Imaging Systems—Novel Cost-Effective Tools for Preclinical Drug Safety and Efficacy Evaluation

Yuval Ramot, Yael S. Schiffenbauer, Robert Maronpot, Abraham Nyska
2017 Toxicological Sciences  
Practical magnetic resonance imaging for use in investigative and preclinical toxicology studies is now feasible.  ...  Newly developed, self-containing imaging systems provide an efficient and cost-effective means to rapidly obtain in vivo and ex vivo magnetic resonance imaging images to improve how we perform toxicology  ...  Y.S.S. is an employee of Aspect Imaging. A.N. serves as a consultant for Aspect Imaging.  ... 
doi:10.1093/toxsci/kfx024 pmid:28329801 fatcat:rpxngjfvavau3jjnkaesk7js2i

Quantitative MR Markers in Non-Myelopathic Spinal Cord Compression: A Narrative Review

Jan Valošek, Petr Bednařík, Miloš Keřkovský, Petr Hluštík, Josef Bednařík, Alena Svátková
2022 Journal of Clinical Medicine  
Thus, we aim to review the ability of qMRI techniques (such as diffusion MRI, diffusion tensor imaging (DTI), magnetization transfer (MT) imaging, and magnetic resonance spectroscopy (1H-MRS)) to serve  ...  However, the prognostic value must be validated in longitudinal studies.  ...  Acknowledgments: We thank Eva Vlčková, from University Hospital Brno, for her rigorous revisions of the text and for providing valuable advice.  ... 
doi:10.3390/jcm11092301 pmid:35566426 pmcid:PMC9105390 fatcat:6ehgkard5bbvznf3qxeec5edle

Hope and Hype of Retinal Vascular Imaging in Cerebral Small Vessel Disease

Michele Cavallari Francesco Orzi
2015 Journal of Neurology & Neurophysiology  
Quantitative retinal imaging is a useful tool to assess risk of development and progression of SVD at the population level.  ...  Editorial Cerebral small vessel disease (SVD) refers to a broad spectrum of disorders, which share magnetic resonance imaging (MRI)-evident abnormalities, such as white matter hyperintensities (WMH), lacunes  ...  Quantitative retinal imaging is a useful tool to assess risk of development and progression of SVD at the population level.  ... 
doi:10.4172/2155-9562.1000e116 fatcat:ripheww4cnclnkzczr2uoibv6u

Brain Segmentation from Super-Resolved Magnetic Resonance Images

Farah Bazzi, Juan D. Dios Rodriguez-Callejas, Caroline Fonta, Ahmad Diab, Hassan Amoud, Omar Falou, Muriel Mescam, Adrian Basarab, Denis Kouame
2019 2019 Fifth International Conference on Advances in Biomedical Engineering (ICABME)  
The objective of this work is to investigate the ability of a 2D super resolution (SR) technique in 3D restoration and enhancement of brain magnetic resonance images to facilitate the study of cerebral  ...  Brain images of the common marmoset, Callithrix jacchus, acquired at different ages are used in this study.  ...  The authors would like to acknowledge AZM and SAADE association and Doctoral School of Science and Technology that provided the necessary financial support for this research.  ... 
doi:10.1109/icabme47164.2019.8940281 fatcat:vhjafixtzna5hfpxs2ve2w7nhu
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