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A genomic history of Aboriginal Australia

Anna-Sapfo Malaspinas, Michael C. Westaway, Craig Muller, Vitor C. Sousa, Oscar Lao, Isabel Alves, Anders Bergström, Georgios Athanasiadis, Jade Y. Cheng, Jacob E. Crawford, Tim H. Heupink, Enrico Macholdt (+63 others)
2016 Nature  
century of research, the origins and evolutionary history of Aboriginal Australians continue to 67 be debated.  ...  We sequenced high-depth genomes (average depth of 75 60X, range 20X-100X) from 83 Aboriginal Australian individuals representing a wide geographical 76 distribution and a broad range of Pama-Nyungan languages  ... 
doi:10.1038/nature18299 pmid:27654914 fatcat:zush6rpjsvg5zgj7xjfgiriowu

Whole-Genome Genetic Diversity in a Sample of Australians with Deep Aboriginal Ancestry

Brian P. McEvoy, Joanne M. Lind, Eric T. Wang, Robert K. Moyzis, Peter M. Visscher, Sheila M. van Holst Pellekaan, Alan N. Wilton
2010 American Journal of Human Genetics  
, Menindee, and Dareton in the Darling River region of western New South Wales, Australia.  ...  Acknowledgments The participants in this study are from the main language groups of Barkindji (Paakintji) and Ngiyambaa and from several associated language groups now living in the communities of Wilcannia  ...  Our study of whole-genome diversity in a sample of participants with deep Aboriginal ancestry adds to the genetic, archaeological, anthropological, and linguistic evidence that Australia has had a long  ... 
doi:10.1016/j.ajhg.2010.07.008 pmid:20691402 pmcid:PMC2917718 fatcat:rdsfxmwoyjhktff7l34nvyan6q

Mitochondrial Genome Variation and Evolutionary History of Australian and New Guinean Aborigines

M. Ingman
2003 Genome Research  
Kijas for valuable comments on an earlier version of this manuscript. This research was supported by a grant from the Swedish Natural Sciences Research Council.  ...  The publication costs of this article were defrayed in part by payment of page charges.  ...  Analyses based on the information content of the entire mitochondrial genome sequence may provide novel insight into the evolutionary history of Australia.  ... 
doi:10.1101/gr.686603 pmid:12840039 pmcid:PMC403733 fatcat:dqwfnjpv7zazxbvknjvz5d2liq

Deep Roots for Aboriginal Australian Y Chromosomes

Anders Bergström, Nano Nagle, Yuan Chen, Shane McCarthy, Martin O. Pollard, Qasim Ayub, Stephen Wilcox, Leah Wilcox, Roland A.H. van Oorschot, Peter McAllister, Lesley Williams, Yali Xue (+2 others)
2016 Current Biology  
The shared phylogenetic history of Aboriginal Australian and Papuan Y chromosomes is consistent with the common origin of these populations as previously inferred from genome-wide data [4, [15] [16] [  ...  Genetic data of two kinds have been proposed to support gene flow from the Indian subcontinent to Australia at this time, as well: first, signs of South Asian admixture in Aboriginal Australian genomes  ... 
doi:10.1016/j.cub.2016.01.028 pmid:26923783 pmcid:PMC4819516 fatcat:vsn3a4gocvaszm6ok6ewhc455e

An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia

M. Rasmussen, X. Guo, Y. Wang, K. E. Lohmueller, S. Rasmussen, A. Albrechtsen, L. Skotte, S. Lindgreen, M. Metspalu, T. Jombart, T. Kivisild, W. Zhai (+46 others)
2011 Science  
The degree to which a single individual is representative of the evolutionary history of Aboriginal Australians more generally is unclear.  ...  (B) PCA plot (PC1 versus PC2) of the studied populations and the ancient genome of the Aboriginal Australian (marked with a cross). Inset shows the greater Australia populations (4).  ...  * Number of sites where a derived allele is shared between outgroup and ingroup 1 subtracted from sites where the derived allele is shared between outgroup and ingroup 2. † Number of sites where a derived  ... 
doi:10.1126/science.1211177 pmid:21940856 pmcid:PMC3991479 fatcat:ic4afpx6gzgpvpwl25dxfbpyru

Out of Africa, into Australia

Michael Gross
2016 Current Biology  
of our shared global history and relatedness.  ...  The fi rst genome of an Australian Aboriginal person was only published in 2011. Even the draft genomes of the Neanderthal were revealed earlier, in May 2010.  ... 
doi:10.1016/j.cub.2016.10.033 fatcat:2hlhiudlpjbsrmntes5fj4cpqe

Aboriginal genome analysis comes to grips with ethics

Ewen Callaway
2011 Nature  
The first complete genome of an Aboriginal Australian is a portrait of a pioneer.  ...  n route from Sydney to Perth, Australia, in the early 1920s, British ethnologist Alfred Cort Haddon acquired a tuft of human hair from a young Aboriginal man.  ... 
doi:10.1038/477522a pmid:21956309 fatcat:hckse5c62fgfzf46grh5zprxga

Geneticists attempt to heal rifts with Aboriginal communities

Ewen Callaway
2016 Nature  
Aboriginal Australian communities have had a troubled history with genetics researchers.  ...  NEWS IN FOCUS © 2 0 1 6 M a c m i l l a n P u b l i s h e r s L i m i t e d , p a r t o f S p r i n g e r N a t u r e . A l l r i g h t s r e s e r v e d .  ...  University of South Australia in Adelaide and an Aboriginal Australian.  ... 
doi:10.1038/537457a pmid:27652541 fatcat:lfde5myuvra73fqwdzd3bu6g2a

Giving it a burl: towards the integration of genetics, isotope chemistry, and osteoarchaeology in Cape York, Tropical North Queensland, Australia

Mark Collard, Sally Wasef, Shaun Adams, Kirsty Wright, R. John Mitchell, Joanne L. Wright, Gabriel Wrobel, Nano Nagle, Adrian Miller, Rachel Wood, Timothy J. Pietsch, Sheila Van Holst Pellekaan (+2 others)
2019 World archaeology  
One is to shed new light on the population history of the region. The other is to develop a methodology to facilitate repatriation of the remains of Aboriginal Australians.  ...  In this paper we outline a worked example of the combined use of genetic data and archaeological evidence. The project focuses on Queensland's Cape York Peninsula and has two goals.  ...  Acknowledgments This paper is dedicated to the memory of our friend and collaborator Mr. Thomas Wales, who was an Elder of the Thaynakwith People.  ... 
doi:10.1080/00438243.2019.1686418 fatcat:7w3txztbvvbchivo3dzun75itu

Socially responsible genetic research with descendants of the First Australians

Sheila M van Holst Pellekaan
2012 Investigative Genetics  
The essence of these guidelines are that research should be carried out with a spirit of integrity, respect, reciprocity, parity, recognition of survival and protection of social and cultural values, a  ...  People experienced in the consultation process are necessary as part of a team.  ...  Many Aboriginal Australian individuals and those from organizations have enriched a sometimes challenging experience and I thank them for their patience, humor, and insight.  ... 
doi:10.1186/2041-2223-3-22 pmid:23151356 pmcid:PMC3528479 fatcat:76rzsmgzo5aandjmxsxpzdo76u

In This Issue

2017 Genetics in Medicine  
A second study, published 6 March 2017 in Nature Genetics, traced mitochondrial genomes of distinct subgroups of Aboriginal communities (two in South Australia, one in Queensland) using DNA extracted from  ...  Some who have a family history of inherited cardiac disease or borderline pathology will never have a cardiac event.  ... 
doi:10.1038/gim.2017.51 fatcat:xdo4kreu6jhipayhxhq2rjh7ku

Ancient nuclear genomes enable repatriation of Indigenous human remains

Joanne L. Wright, Sally Wasef, Tim H. Heupink, Michael C. Westaway, Simon Rasmussen, Colin Pardoe, Gudju Gudju Fourmile, Michael Young, Trish Johnson, Joan Slade, Roy Kennedy, Patsy Winch (+16 others)
2018 Science Advances  
the present) of known provenance and compared them to 100 high-coverage contemporary Aboriginal Australian genomes, also of known provenance.  ...  Our findings demonstrate the feasibility of successfully identifying the origins of unprovenanced ancestral remains using genomic methods.  ...  We thank the National Throughput DNA Sequencing Centre at the University of Copenhagen, Novogene Bioinformatics and Kinghorn Centre for Clinical Genomics for DNA sequencing, G.  ... 
doi:10.1126/sciadv.aau5064 pmid:30585290 pmcid:PMC6300400 fatcat:5v7p2bmjn5djvom6i4ghlrjuwm

Genetic research in Indigenous health: significant progress, substantial challenges

Emma E Kowal
2012 Medical Journal of Australia  
the health of every human. 8 Indigenous genetic research in Australia Given this history, it is understandable that little genetic research has taken place in Indigenous Australia.  ...  This was a study of the genetic associations between metabolic disease and otitis media in a remote Aboriginal community in Western Australia.  ... 
doi:10.5694/mja.12.11113 pmid:23025733 fatcat:lkpkyjuqtzgcnmt7qxzsr3vkum

Genetic research in Indigenous health: significant progress, substantial challenges

Emma E Kowal
2012 Medical Journal of Australia  
the health of every human. 8 Indigenous genetic research in Australia Given this history, it is understandable that little genetic research has taken place in Indigenous Australia.  ...  This was a study of the genetic associations between metabolic disease and otitis media in a remote Aboriginal community in Western Australia.  ... 
doi:10.5694/mja12.10531 pmid:22762219 fatcat:7x7emdry3vc5hec6xkboss7mxm

From Songlines to genomes: Prehistoric assisted migration of a rain forest tree by Australian Aboriginal people

Maurizio Rossetto, Emilie J. Ens, Thijs Honings, Peter D. Wilson, Jia-Yee S. Yap, Oliver Costello, Erich R. Round, Claire Bowern, Renee M. Borges
2017 PLoS ONE  
Here we integrate historic and biocultural research involving Aboriginal people, with chloroplast and nuclear genomic data to demonstrate Aboriginal-mediated dispersal of a non-cultivated rainforest tree  ...  analyzing a comparative sample from northern Australia.  ...  Acknowledgments We wish to acknowledge the Traditional Owners past, present and future of where this study was situated. We thank the Githabul Rangers, D. Williams, S. Wheildon, R. Heron, R.  ... 
doi:10.1371/journal.pone.0186663 pmid:29117184 pmcid:PMC5695580 fatcat:2vsvyh5mljfndf3gvr2wlorpfa
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