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The expanded spectrum of neuromyelitis optica: evidences for a new definition

Marco A Lana-Peixoto, Dagoberto Callegaro
2012 Arquivos de Neuro-Psiquiatria  
On the opposite way, other patients have optic neuritis or LETM in association with typical lesions of NMO on brain MRI and yet are AQP4-IgG seronegative.  ...  Neuromyelitis optica (NMO) has been traditionally described as the association of recurrent or bilateral optic neuritis and longitudinally extensive transverse myelitis (LETM).  ...  For over 100 years, the terms neuromyelitis optica (NMO) and Devic's disease were employed to identify patients with a condition considered as a variant of multiple sclerosis (MS), in which symptoms were  ... 
doi:10.1590/s0004-282x2012001000010 pmid:23060108 fatcat:mljkqwhsa5aqfmzwyst5ir3pxy

Neuromyelitis optica: a challenging diagnosis at secondary hospital

Anna Paula Romero de Oliveira, Patrícia Tarantoa, Lívia Herbsta, Andre Kirihara, Maira Leticia Veras, André Macedo Serafim Silva, Marcio Ricardo Taveira Garcia, Angelina Maria Martins Lino
2013 Autopsy and Case Reports  
A few days prior to hospital admission, the muscle strength in her lower limbs became worse and ascended to the upper limbs associated with sensory changes in the trunk and voiding dysfunction.  ...  Known since the 19th century, neuromyelitis optica (NMO), or Devic's disease, is an idiopathic immune-mediated inflammatory demyelinating disease of the central nervous system selectively affecting the  ...  This was associated with sensory changes in the trunk and urinary incontinence.  ... 
doi:10.4322/acr.2013.008 pmid:31528598 pmcid:PMC6671879 fatcat:6avj5nkcircdnmlna4rjf7iapy

Altered Microstructure of Cerebral Gray Matter in Neuromyelitis Optica Spectrum Disorder-Optic Neuritis: A DKI Study

Hanjuan Zhang, Qing Li, Lei Liu, Xiaoxia Qu, Qian Wang, Bingbing Yang, Junfang Xian
2021 Frontiers in Neuroscience  
The purpose of this study was to analyze microstructural alterations in cerebral gray matter using non-Gaussian diffusion kurtosis imaging (DKI) in neuromyelitis optica spectrum disorder (NMOSD) patients  ...  For NMOSD-ON patients, microstructural abnormalities in the occipital visual cortex are correlated with clinical disability.  ...  Cortical Thinning Correlates with Cognitive Change in Multiple Sclerosis but not in Neuromyelitis Optica. Eur.  ... 
doi:10.3389/fnins.2021.738913 pmid:34987355 pmcid:PMC8720872 fatcat:ut4ypg3tnzh4tffo4nmt7546om

Aquaporin 4 and neuromyelitis optica

Marios C Papadopoulos, AS Verkman
2012 Lancet Neurology  
The discovery of circulating IgG1 antibodies against the astrocyte water channel protein aquaporin 4 (AQP4) and the evidence that AQP4-IgG is involved in the development of neuromyelitis optica revolutionised  ...  Neuromyelitis optica is an infl ammatory demyelinating disorder of the CNS.  ...  The funding sources were not involved in writing the manuscript or the decision to submit for publication.  ... 
doi:10.1016/s1474-4422(12)70133-3 pmid:22608667 pmcid:PMC3678971 fatcat:ilbbwj42zbf2hpk2ai2gjpymwu

Neuromyelitis optica with brain stem involvement in a middle-aged Ethiopian woman: a case report and review of literature

Rodas Asrat Kassu, Hailu Abera Mulatu, Sisay Gizaw, Henok Fisseha, Amir Musema, Ayube Keder, Semere Negash, Fithanegest Tefera, Adugna Lissanwerk, Lemlem Tamrat
2021 Journal of Medical Case Reports  
It reminds clinicians to suspect neuromyelitis optica in a patient who presented with unexplained recurrent optic neuritis to make a timely diagnosis and prevention of permanent neuronal damage.  ...  Neuromyelitis optica can also be associated with oculomotor nerve involvement.  ...  We are also grateful to the professional contribution of physicians and nurses of the St Paul's Hospital Millennium Medical College in the care of the patient.  ... 
doi:10.1186/s13256-021-03019-6 pmid:34598735 fatcat:2nkhfm4tnzcrhcyn75ncl42kji

A Narrative Review on Neuromyelitis Optica

Gabriel Alugba, Alexsandra Urhi, Gibson O. Anugwom, Samuel O. Ilikannu, Omotola Akinade, Oboseh J. Ogedegbe, Tioluwani K. Ojo, Ayodeji D. Johnson, Kingsley C. Nwadi
2022 Journal of Advances in Medicine and Medical Research  
Neuromyelitis Optica, also known as Devic's disease, is a central nervous system (CNS) autoimmune inflammatory disease that primarily affects the optic nerve and spinal cord.  ...  In this study, we discussed extensively this disease entity by describing the epidemiology, pathogenesis, clinical features, management, and prognosis.  ...  ACKNOWLEDGEMENTS All authors of this review certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants;  ... 
doi:10.9734/jammr/2022/v34i1331377 fatcat:cnfdvzbjendk7anci2omyf5xrq

Comparison of spontaneous brain activity revealed by regional homogeneity in AQP4-IgG neuromyelitis optica-optic neuritis versus MOG-IgG optic neuritis patients: a resting-state functional MRI study

Junqing Wang, Yuan Tian, Yi Shao, Hui Feng, Limin Qin, Weiwei Xu, Hongjuan Liu, Quangang Xu, Shihui Wei, Lin Ma
2017 Neuropsychiatric Disease and Treatment  
This was not an industry-supported study. This work was supported by a grant from the National High Technology Research and Development Program of China (863 Program; No 2015AAO20511).  ...  Acknowledgments The authors thank the following authors who collected the fMRI data of the study: Mingge Li, Huanfen Zhou, Honglu Song, Da Teng, Dahe Lin, and Nanping Ai.  ...  In addition, Wang et al 36 reported that NMO is associated with markedly decreased GM volume in the temporal cortices.  ... 
doi:10.2147/ndt.s145183 pmid:29123400 pmcid:PMC5661477 fatcat:hunqd7x7f5hhnhmtkxox6eusym

Author Index to Volume 31 - 2004

2004 Canadian Journal of Neurological Sciences  
Case Report 554 (NOV) DYSGENESIS Neuroimaging Highlight: Functional Imaging of the Double Cortex 254 (MAY) DYSPLASIAS Functional MRI Study of Verbal Fluency in a Patient with Subcortical Laminar  ...  of 2003 194 (MAY) DEVIC'S Devic's Neuromyelitis Optica Treated with Intravenous Gamma Globulin (IVIG) 265 (MAY) DISC HERNIATION Synchronous Lumbar Disc Herniation in Adult Twins.  ... 
doi:10.1017/s0317167100003887 fatcat:avfrgwm5grentcofcac2j6v77y

Challenge Epilepsy---New Antiepileptic Drugs

S. WROE
2000 Journal of Neurology, Neurosurgery and Psychiatry  
Service of Ophthalmology Devic's neuromyelitis optica: a clinicopatho- logical study of eight patients.  ...  Swelling and signal change on MRI extending beyond a single segment are more frequent in neuromyelitis optica and cavitation can be seen.  ...  Link between the CSF shunt and achievement in adults with spina bifida. J Neurol Neurosurg Psychiatry 1999;67:591-5.  ... 
doi:10.1136/jnnp.68.6.801d pmid:10811717 pmcid:PMC1736979 fatcat:aajfmuxadbf45oj3ajutu5oss4

Febrile Hashimoto's encephalopathy

P. PAPATHANASOPOULOS
2000 Journal of Neurology, Neurosurgery and Psychiatry  
Swelling and signal change on MRI extending beyond a single segment are more frequent in neuromyelitis optica and cavitation can be seen.  ...  Devic's neuromyelitis optica and HIV-1 infection Neuromyelitis optica (Devic's syndrome) can be defined as a severe transverse myelitis, an acute unilateral or bilateral optic neuropathy, no clinical involvement  ... 
doi:10.1136/jnnp.68.6.795 pmid:10877624 pmcid:PMC1736966 fatcat:2xkmwvtefbdkna5icgjji3mwau

McAlpine's Multiple Sclerosis. Third edition

R. WALKER
2000 Journal of Neurology, Neurosurgery and Psychiatry  
Service of Ophthalmology Devic's neuromyelitis optica: a clinicopatho- logical study of eight patients.  ...  Swelling and signal change on MRI extending beyond a single segment are more frequent in neuromyelitis optica and cavitation can be seen.  ...  Link between the CSF shunt and achievement in adults with spina bifida. J Neurol Neurosurg Psychiatry 1999;67:591-5.  ... 
doi:10.1136/jnnp.68.6.801a pmid:10811714 pmcid:PMC1736968 fatcat:c276ebuqdbek7egrhx7ao6rtju

Advances in Multiple Sclerosis-Clinical Research and Therapy

M. BARNES
2000 Journal of Neurology, Neurosurgery and Psychiatry  
Service of Ophthalmology Devic's neuromyelitis optica: a clinicopatho- logical study of eight patients.  ...  Swelling and signal change on MRI extending beyond a single segment are more frequent in neuromyelitis optica and cavitation can be seen.  ...  Link between the CSF shunt and achievement in adults with spina bifida. J Neurol Neurosurg Psychiatry 1999;67:591-5.  ... 
doi:10.1136/jnnp.68.6.801e pmid:10811718 pmcid:PMC1736984 fatcat:jnz26rnoyfdt7f5jbvgrywae3u

Botulinum Toxin in the Treatment of Cerebral Palsy

M. P BARNES
2000 Journal of Neurology, Neurosurgery and Psychiatry  
Service of Ophthalmology Devic's neuromyelitis optica: a clinicopatho- logical study of eight patients.  ...  Swelling and signal change on MRI extending beyond a single segment are more frequent in neuromyelitis optica and cavitation can be seen.  ...  Link between the CSF shunt and achievement in adults with spina bifida. J Neurol Neurosurg Psychiatry 1999;67:591-5.  ... 
doi:10.1136/jnnp.68.6.801 pmid:10811713 pmcid:PMC1736963 fatcat:dhsydxgqwbcahcu54d6czns4qi

Pseudotumoral Demyelinating Lesions: A Presentation of Acute Disseminated Encephalomyelitis

Rachid Belfkih, Omar Ghomari Khayat, Hind H'daidane, Fatima Zahra El Amrani
2021 Case Reports in Neurology  
In this case report, we present a 35-year-old male patient hospitalized in the department of neurology for a rapidly progressive onset of encephalopathy and polyfocal neurological deficits, with pseudotumoral  ...  These lesions could also be seen in myelin oligodendrocyte glycoprotein antibody-associated demyelination, acute disseminated encephalomyelitis (ADEM), and neuromyelitis optica spectrum disorder.  ...  Neuromyelitis optica, also called Devic's disease, is a CNS inflammatory affection that differs from MS, usually associated with serum aquaporin-4 immunoglobulin G antibodies (AQP4-IgG).  ... 
doi:10.1159/000515174 pmid:34177535 pmcid:PMC8215961 fatcat:pbttqsijk5dfbetlngdpxmebpy

Pactrims Invited Lecture / Ordinary Submission

2015 Multiple Sclerosis  
Objective: To investigate cognitive function and MRI-measured brain volume and cortical thickness in patients with neuromyelitis optica spectrum disorder (NMOSD) in comparison with those in patients with  ...  Chronic pain is a major source of disability in patients with multiple sclerosis (MS) and neuromyelitis optica (NMO).  ...  Objective: The aim of this study is to explore the relationship of the NLR with disease activity in terms of symptom severity, lesion size and prognosis in iATM patients.  ... 
doi:10.1177/1352458514563659 pmid:28080249 fatcat:pil4lerkprbv7hc4qitoqsitgm
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