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A Multilayer Ontology of Instruments for Neurological, Behavioral and Cognitive Assessments

Bénédicte Batrancourt, Michel Dojat, Bernard Gibaud, Gilles Kassel
2014 Neuroinformatics  
Here, we report on an extension of this ontology to the representation of instruments used to assess brain and cognitive functions and behavior in humans.  ...  with the information on each subject's neurologic states, cognitive assessments and behavioral scores derived from questionnaires and tests.  ...  Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s)  ... 
doi:10.1007/s12021-014-9244-3 pmid:25240319 pmcid:PMC4303739 fatcat:aguax7z46nbt5f4eged6bgdfle

A propositional representation model of anatomical and functional brain data

Pablo Maturana, Bénédicte Batrancourt
2011 Journal of Physiology - Paris  
For example, the graph model has been used in neuroimaging research as a methodological tool to examine brain network organization, topology and complex dynamics, as well as as a framework to test the  ...  In the current work we propose a network of anatomical brain data and neuropsychological assessments linked to the functions explored in these assessments, offering a platform to visualize, in a single  ...  Acknowledgements This work is supported by IFRAD (International Fund Raising for Alzheimer's disease).  ... 
doi:10.1016/j.jphysparis.2011.07.016 pmid:21854847 fatcat:kpclijhzsbfrvhngr7vryubwty

Movement disorders ontology for clinically oriented and clinicians-driven data mining of multi-center cohorts in Parkinson's disease [article]

Deepak K Gupta, Massimo Marano, Raj Aurora, James Boyd, Satya Sahoo
2020 medRxiv   pre-print
However, these is a clear lack of a common terminological system or ontology that can support query analysis of datasets in AMP PD and map across multiple instruments used in the assessment of PD as well  ...  To address these challenges, we developed the Movement Disorder Ontology (MDO) that used a systematic analysis of movement disorder instruments, extensive review of literature led by a movement disorder  ...  for Advancing Translational Science (NCATS), Clinical and Translational Science Award (CTSA) grant, UL1TR002548.  ... 
doi:10.1101/2020.11.09.20228577 fatcat:yqnltnwnizfplhhyvhait7lkaq

Editorial: New Perspectives in Psychopathology

Diogo Telles Correia, Elie Cheniaux
2020 Frontiers in Psychiatry  
(ES) task and a numerical Stroop (NS) task, causing different types of interferences, were used for assessing the emotional and cognitive aspects of attentional control ability (behavioral data).  ...  In "From Affective Science to Psychiatric Disorder: Ontology as a Semantic Bridge", where the authors propose and discuss an ontological framework for explicitly capturing the complex interrelations between  ...  Conflict of Interest: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.  ... 
doi:10.3389/fpsyt.2019.01009 pmid:32116824 pmcid:PMC7008230 fatcat:qike2yvbpjemvnramrt6ueiquq

Modeling functional Magnetic Resonance Imaging (fMRI) experimental variables in the Ontology of Experimental Variables and Values (OoEVV)

Gully A.P.C. Burns, Jessica A. Turner
2013 NeuroImage  
Neuroimaging data is raw material for cognitive neuroscience experiments, leading to scientific knowledge about human neurological and psychological disease, language, perception, attention and ultimately  ...  OoEVV is designed to be compatible with the XCEDE neuroimaging data standard for data collection terminology, and with the Cognitive Paradigm Ontology (CogPO) for specific reasoning elements of neuroimaging  ...  The OoEVV system is our instantiation of the capability to allow domain scientists to develop a local ontology of terminology within their current domain.  ... 
doi:10.1016/j.neuroimage.2013.05.024 pmid:23684873 pmcid:PMC4474486 fatcat:t7seoiv4krhrxoomdq555dimjm

Integrative Base Ontology for the Research Analysis of Alzheimer's Disease-Related Mild Cognitive Impairment

Alba Gomez-Valades, Rafael Martinez-Tomas, Mariano Rincon
2021 Frontiers in Neuroinformatics  
Ontologies have emerged as a solution to this problem due to their capacity for homogenization and consensus in the representation and reuse of data.  ...  Early detection of mild cognitive impairment (MCI) has become a priority in Alzheimer's disease (AD) research, as it is a transitional phase between normal aging and dementia.  ...  ACKNOWLEDGMENTS We would like to thank Maria del Carmen Mardomingo and Sara García Herranz for permission to use their database in our project.  ... 
doi:10.3389/fninf.2021.561691 pmid:33613222 pmcid:PMC7889797 fatcat:7t6mi5us4bfzrlb2ymwrer6uzy

Grid-wide neuroimaging data federation in the context of the NeuroLOG project

Franck Michel, Alban Gaignard, Farooq Ahmad, Christian Barillot, Bénédicte Batrancourt, Michel Dojat, Bernard Gibaud, Pascal Girard, David Godard, Gilles Kassel, Diane Lingrand, Grégoire Malandain (+5 others)
2010 Studies in Health Technology and Informatics  
It addresses the integration of brain image files, associated relational metadata and neuroscience semantic data in a heterogeneous distributed environment, integrating legacy data managers through a mediation  ...  This paper describes the NeuroLOG platform design and implementation, shedding light on its Data Management Layer.  ...  The NeuroLOG platforms owes a lot to our clinical colleagues providing the databases exploited (Pr Gilles Edan and Dr Jean-Christophe Ferré in Rennes, Pr Jean-François Lebas in Grenoble, clinicians of  ... 
pmid:20543431 pmcid:PMC2938713 fatcat:upx43zpnpjfolku2cwtghguko4

An ontology of psychedelic entity experiences in evolutionary psychology and neurophenomenology

Michael James Winkelman
2018 Journal of Psychedelic Studies  
The extensive interaction of DMT with the receptorome explains why these experiences give such a powerful sense of ontological certainty.  ...  Mechanisms are proposed to involve innate modules, operators, and intelligences that underlie ordinary cognitive inferences and provide the basis for supernatural thought.  ...  Acknowledgements: The author would like to thank Nicholas Sampson for helpful suggestions in formulating this paper and Heather Hargraves for comments on a draft of the paper.  ... 
doi:10.1556/2054.2018.002 fatcat:r6i4wtodgranxec7s5iogxloka

Editorial: MAPPING: MAnagement and Processing of Images for Population ImagiNG

Michel Dojat, David N. Kennedy, Wiro Niessen
2017 Frontiers in ICT  
A multilayer ontology of instruments for neurological, behavioral and cognitive assessments.  ...  entities and relations in medical imaging, neuropsychological, and behavioral assessment domains.  ... 
doi:10.3389/fict.2017.00018 fatcat:svvyijjih5bhhdk3pofz7az5ye

Insight: Semantic provenance and analysis platform for multi-center neurology healthcare research

Priya Ramesh, Annan Wei, Elisabeth Welter, Yvan Bamps, Shelley Stoll, Ashley Bukach, Martha Sajatovic, Satya S. Sahoo
2015 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)  
In addition, the paper describes the use of descriptive logic-based OWL2 epilepsy ontology for cohort queries with "expansion of query expression" using ontology reasoning.  ...  Insight is a Semantic Web technology-based platform to support large-scale secondary analysis of healthcare data for neurology clinical research.  ...  They are: administrative core, clinical core and configuration cores. There are a total of 10 data models for the 3 cores.  ... 
doi:10.1109/bibm.2015.7359776 pmid:27069752 pmcid:PMC4826045 fatcat:wgzawqj7wzh7tdvginedyqlery

Complexity across scales: a walkthrough to linking neuro-imaging readouts to molecular processes

Anandhi Iyappan, Sepehr Golriz Khatami, Martin Hofmann-Apitius
2017 Journal of Systems and Integrative Neuroscience  
They help in measuring the structure of white matter as well as fiber connectivity within and across brain regions [36][37][38]. Fractional anisotropy is a numerical measure of fiber integrity.  ...  Many histopathological studies have proposed that AD are often related to damage of specific cortical layers such as neocortex and entorhinal cortex [31,32].  ...  This ontology consists of 488 terms and they consist of classes such as imaging agent, imaging instrument or biological intervention.  ... 
doi:10.15761/jsin.1000151 fatcat:oomqcbhhrbgfjaobbrvn25lcnq

Cerebrospinal Fluid Proteome Alterations Associated with Neuropsychiatric Symptoms in Cognitive Decline and Alzheimer's Disease

Magdalena Mroczek, Christopher Clark, Loïc Dayon, Gene L. Bowman, Julius Popp
2022 Cells  
In a longitudinally followed-up cohort of subjects with normal cognition and patients with cognitive impairment (MCI and mild dementia) from a memory clinic setting, we quantified a panel of 790 proteins  ...  Out of the selected proteins, three were associated with accelerated cognitive decline at follow-up visits after controlling for possible confounders.  ...  Conflicts of  ... 
doi:10.3390/cells11061030 pmid:35326481 pmcid:PMC8947516 fatcat:ggxuwu35sfbmndlhmlt6q6oiwq

Deep phenotyping in 3q29 deletion syndrome: recommendations for clinical care

Rossana Sanchez Russo, Michael J Gambello, Melissa M Murphy, Katrina Aberizk, Emily Black, T Lindsey Burrell, Grace Carlock, Joseph F Cubells, Michael T Epstein, Roberto Espana, Katrina Goines, Ryan M Guest (+12 others)
2021 Genetics in Medicine  
Thirty-two individuals with the 3q29 deletion were evaluated using a defined phenotyping protocol and standardized data collection instruments.  ...  To develop evidence-based recommendations using these data for effective clinical care.  ...  Funding for this work was provided by National Institutes of Health (NIH) grants R01 MH110701 and R01 MH118534. REDCap is supported by grant UL1 TR000424. AUTHOR CONTRIBUTIONS  ... 
doi:10.1038/s41436-020-01053-1 pmid:33564151 pmcid:PMC8105170 fatcat:h4vwhognrvavbdy6ky2etxqcyq

Modeling Mind and Matter: Reductionism and Psychological Measurement in Cognitive Neuroscience

Rogier A. Kievit, Jan-Willem Romeijn, Lourens J. Waldorp, Jelte M. Wicherts, H. Steven Scholte, Denny Borsboom
2011 Psychological Inquiry  
In this rejoinder, we address the core points of criticism and present an expansion of the ideas we formulate in the Kievit et al.  ...  Most important, they show that psychometric models yield increased depth and precision in dialogues concerning the foundational questions of cognitive neuroscience.  ...  None of the materials have been published elsewhere. We thank Angelique Cramer, Petry Kievit-Tyson, and Anne-Laura van Harmelen for valuable comments on earlier versions of this article.  ... 
doi:10.1080/1047840x.2011.567962 fatcat:s7ds37qeczdbrd2hcgctw62yze

Perspectives on next steps in classification of oro-facial pain - part 2: role of psychosocial factors

J. Durham, K. G. Raphael, R. Benoliel, W. Ceusters, A. Michelotti, R. Ohrbach
2015 Journal of Oral Rehabilitation  
of orofacial pain conditions, and how this information can optimally be used for developing a structured orofacial pain classification system for research.  ...  , and the usage of classification system for guiding treatment.  ...  Ceusters and R. Ohrbach) from the National Institute of Dental and Craniofacial Research.  ... 
doi:10.1111/joor.12329 pmid:26257252 pmcid:PMC4715752 fatcat:isfyfs7qajdufcogu2ujamvcxm
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