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Pharmacogenomics competencies in pharmacy practice: A blueprint for change
2017
Journal of the American Pharmacists Association
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In 2011, the Pharmacogenomics Special Interest Group of the American Association of Colleges of Pharmacy led a process to update this competency statement using a consensus-based method that incorporated ...
The first pharmacogenomics competency statement for pharmacists was published in 2002. ...
In addition to the need for a standardized, competency-based approach to pharmacogenomics education, efforts that support identification and dissemination of best practice models for integrating clinical ...
doi:10.1016/j.japh.2016.08.014
pmid:27816542
pmcid:PMC5373920
fatcat:4pruyvx7wbawvcd2gfawvtj7k4
A Continuing Professional Development Program for Pharmacists Implementing Pharmacogenomics into Practice
2020
Pharmacy
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A continuing professional development (CPD) program for pharmacists practicing in community and team-based primary care settings was developed and evaluated using Moore's framework for the assessment of ...
integrate this new service into their practices. ...
Determining the optimal strategies for meeting the educational needs of practicing pharmacists is needed to implement pharmacogenomics services as a common offering within community-based pharmacy practices ...
doi:10.3390/pharmacy8020055
pmid:32231164
fatcat:kclbfodk6zblfl7fgimmbsmyzq
Pharmacists Leading the Way to Precision Medicine: Updates to the Core Pharmacist Competencies in Genomics
2021
American Journal of Pharmaceutical Education
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Competencies available through the Genetics/Genomics Competency Center provide a framework for pharmacogenomics instruction in both pharmacy school curricula and continuing education programs. ...
The process used a systematic approach which included mapping pharmacogenomics-specific competencies to the entrustable professional activities for pharmacists and seeking consensus from key stakeholders ...
the Genetics/Genomics Competency Center website and disseminating the updated pharmacist competencies in genomics on that platform; and members of the AACP Pharmacogenomics Special Interest Group for ...
doi:10.5688/ajpe8634
pmid:34301570
fatcat:7wpnizj27natffie36ra4oxp3m
Integrating pharmacogenomics into pharmacy practice via medication therapy management
2011
Journal of the American Pharmacists Association
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New applications and processes for using this emerging pharmacogenomics data are needed to effectively integrate this information into clinical practice. ...
Conclusion: To achieve integration of pharmacogenomics into clinical practice via MTM, the pharmacy profession must define a process for the application of pharmacogenomic data into pharmacy clinical practice ...
Through a number of working groups, the program also establishes a framework for electronic transmission of pharmacogenomic data from current EHR databases. ...
doi:10.1331/japha.2011.11543
pmid:22001957
fatcat:ghnfyo6renccbjgfn3emv2ld4i
A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health
2018
PLoS Medicine
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integration of sequencing alongside other medical services. ...
OPEN ACCESS Citation: Khoury MJ, Feero WG, Chambers DA, Brody LE, Aziz N, Green RC, et al. (2018) A collaborative translational research framework for evaluating and implementing the appropriate use of ...
Institutes for Health. ...
doi:10.1371/journal.pmed.1002631
pmid:30071015
pmcid:PMC6071954
fatcat:dajkdqdgnrh5fmvdmrnt3h5l6m
Evolving Research and Stakeholder Perspectives on Pharmacogenomics
2011
Journal of the American Medical Association (JAMA)
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Several large pharmacy benefits managers have taken a proactive role in providing pharmacogenomics services, and in establishing the systems and evidence base to support their use. ...
There are no uniform evidentiary standards for clinical implementation, but frameworks have been created by groups such as EGAPP and CPIC. 2, 10 Clinicians considering a pharmacogenomic test should consider ...
Table Checklist for consideration of a pharmacogenomic test 1 Is there a relationship between the test result and response to drug therapy?
2 Have the initial results been validated? ...
doi:10.1001/jama.2011.1343
pmid:21934059
pmcid:PMC3559013
fatcat:gm2qoluedvfprbty6cfwfexlua
Towards pharmacogenomics knowledge discovery with the semantic web
2009
Briefings in Bioinformatics
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Several XML markup languages have been developed to capture pharmacogenomic and related information so as to facilitate data sharing. ...
However, recent advances in semantic web technologies have presented exciting new opportunities for pharmacogenomics knowledge discovery by representing the information with machine understandable semantics ...
Data integration in the HCLS has been enormously facilitated by the use of the eXtensible Markup Language (XML), which provides a validation procedure for document structure based on a corresponding XML ...
doi:10.1093/bib/bbn056
pmid:19240125
fatcat:p53mx2t3gbeupmz625c6jyykui
Towards an interoperable information infrastructure providing decision support for genomic medicine
2011
Studies in Health Technology and Informatics
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Here we describe our work and future visions around the creation of a distributed infrastructure for pharmacogenetic data and medical decision support, based on industry standards such as the Web Ontology ...
Genetic dispositions play a major role in individual disease risk and treatment response. ...
We expect the research programme outlined in this paper to have several implications for clinical practice, such as improving the translation of basic pharmacogenomic findings into clinical practice, increasing ...
pmid:21893735
fatcat:v5vvyj6jwndrlmf46rchf6idxm
Semantically enabling pharmacogenomic data for the realization of personalized medicine
2012
Pharmacogenomics (London)
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play a critical role in data integration. ...
Many of the datasets listed in [12] to represent pharmacogenomic findings, and creating services for accessing the nascent infrastructure. ...
doi:10.2217/pgs.11.179
pmid:22256869
pmcid:PMC3957334
fatcat:q7o2vfijn5hmlasoaskcjjopkq
Pharmacogenomic testing to support prescribing in primary-care: a structured review of implementation models
2021
Pharmacogenomics (London)
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This review identified 13 studies describing eight implementation models utilizing a multi-gene pharmacogenomic panel within a primary care or community setting. ...
They demonstrated importance and feasibility of pre-test counseling, the role of the pharmacist, data integration into the electronic medical record and point-of-care clinical decision support systems ...
A condition-based PGx MDSS in primary care integrating patient data with PGx data to give medication and dosage recommendations is feasible and accessed regularly, being utilized 236-times for 190 patients ...
doi:10.2217/pgs-2021-0032
pmid:34467776
pmcid:PMC8438972
fatcat:yjj5tslr4bazrnrfi2e7ztskga
Development of Customizable Implementation Guides to Support Clinical Adoption of Pharmacogenomics: Experiences of the Implementing GeNomics In pracTicE (IGNITE) Network
2020
Pharmacogenomics and Personalized Medicine
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This expansion was led by a multidisciplinary team that developed an evidence-based, structured framework for the guides, oversaw the technical process/build, and pilot tested the first guide, CYP2C19- ...
Sixty-five resources were collected from 12 institutions and categorized according to a seven-step implementation framework for the pilot CYP2C19-Clopidogrel Testing Implementation Guide. ...
Step 4: Integrate genetic data into the EHR
Build clinical decision support and integrate genetic test results into the EHR. ...
doi:10.2147/pgpm.s241599
pmid:32765043
pmcid:PMC7373415
fatcat:hxc4mphzfbh2xokq6r7u3eo35q
Engineering Requirements of a Herpes Simplex Virus Patient Registry: Discovery Phase of a Real-World Evidence Platform to Advance Pharmacogenomics and Personalized Medicine
2019
Biomedicines
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and allow for this data to be used as a complement to genomic and clinical data to further the treatment of HSV. ...
Comprehensive pharmacogenomic understanding requires both robust genomic and demographic data. Patient registries present an opportunity to collect large amounts of robust, patient-level data. ...
Acknowledgments: We would like to thank Skein Ltd. for their continued work in the development of this platform.
Conflicts of Interest: The authors declare no conflict of interest. ...
doi:10.3390/biomedicines7040100
pmid:31847458
fatcat:3bfnj2kk7bcbjgqrwmi42jj3jy
Using systems approaches to address challenges for clinical implementation of pharmacogenomics
2013
Wiley Interdisciplinary Reviews: Systems Biology and Medicine
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framework that views drug response as a dynamic system and maps ...
decision-making through complex biological models, improving strategies for integrating genomics into clinical practice, and evaluating the impact of implementation programs on public health. ...
Manual integration of an extensive and ever-changing pharmacogenomic knowledge base into the point of care is unreasonable for most clinicians. 51 Provision of electronic decision support will mitigate ...
doi:10.1002/wsbm.1255
pmid:24319008
pmcid:PMC3944797
fatcat:sszvdpramzes3a5fi4ujq6zf2a
Professional opportunity for pharmacists to integrate pharmacogenomics in medication therapy
2018
Canadian Pharmacists Journal / Revue des Pharmaciens du Canada
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the framework of a research project ...
Professional opportunity for pharmacists to integrate pharmacogenomics in medication therapy Iris Cohn, MSc(Pharm), RPh; Ronald D. ...
doi:10.1177/1715163518766376
pmid:29796128
pmcid:PMC5958433
fatcat:laxf5ee3ujejrbl23kkuvarvqq
Integration of Genomics Data and Electronic Health Records Toward Personalized Medicine: A Targeted Review
2021
Frontiers in Health Informatics
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much as possible, an integrated online patient portal, multiple data source handling, machine-readable storing and reporting, research-oriented requirements, pharmacogenomics decision support capabilities ...
Integration requirements also consisted of nine functional cases including a uniform approach to the interpretation of genetic tests, standardized terminologies and ontologies, structured data entry as ...
At a higher level, knowledge sharing requires appropriate standards for interoperable data representations. Messaging frameworks adapted with HIT terminologies are also a critical task. ...
doi:10.30699/fhi.v10i1.299
fatcat:5rzxdhkovrhbbnsave35i2i42a
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