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Cognitive Dysfunctions and Assessments in Multiple Sclerosis

Celia Oreja-Guevara, Teresa Ayuso Blanco, Luis Brieva Ruiz, Miguel Ángel Hernández Pérez, Virginia Meca-Lallana, Lluís Ramió-Torrentà
2019 Frontiers in Neurology  
This review is a comprehensive and short update of the literature on cognitive dysfunctions, the possible confounders and the impact of quality of life in patients with multiple sclerosis.  ...  It remains a major cause of neurological disability in young and middle-aged adults suffering from the disease.  ...  Memory Memory difficulties have been found in 40-65% of patients, with 30% of patients having severe memory problems (36) .  ... 
doi:10.3389/fneur.2019.00581 pmid:31214113 pmcid:PMC6558141 fatcat:bilxkc4bpbcufftucvhfo7b5dq

Neurobehavioral testing in human risk assessment

Diane S. Rohlman, Roberto Lucchini, W. Kent Anger, David C. Bellinger, Christoph van Thriel
2008 Neurotoxicology  
Even as exposures in the workplace are reduced, they have been increasing in the environment and research on exposure has now expanded to cross the entire lifetime.  ...  Neurobehavioral tests are being increasingly used in human risk assessment and there is a strong need for guidance.  ...  OHSU and Drs Anger and Rohlman have a significant financial interest in Northwest Education Training and Assessment, LLC, a company that may have a commercial interest in the results of this research and  ... 
doi:10.1016/j.neuro.2008.04.003 pmid:18539229 pmcid:PMC2492890 fatcat:3cv4m2i4lrbgxbvbwan7jlwzvy

Acute severe asthma: Part 1. Pathophysiology and clinical assessment

Robert G. Garmon, Richard B. Zemenick
1992 The Journal of the American Osteopathic Association  
Concomitant use of lithium and verapamil may result in a lowering of serum lithium levels or increased sensitivity to lithium. Patients receiving both drugs must be monitored carefully.  ...  However, systemic anaphylaxis should be considered in patients having a sudden onset of difficulty breathing or wheezing.  ... 
doi:10.1515/jom-1992-920217 fatcat:dsdvvjxgsrg2rj6gh6l44mycdi

Detection of neurocognitive feigning: development of a multi-strategy assessment

S Bender
2004 Archives of Clinical Neuropsychology  
Using a simulation design with a manipulation check and both positive and negative incentives, two groups of simulators (Cautioned and NonCautioned) were compared with brain-injured patients and nonimpaired  ...  Neuropsychological assessments can be completely invalidated by persons successfully feigning neurocognitive impairment.  ...  With multiple strategies, Rogers (1997) suggested that cautions are not likely to reduce the effectiveness of the strategies and even have a paradoxical effect in improving detection.  ... 
doi:10.1016/s0887-6177(02)00165-8 pmid:14670379 fatcat:ascxfm7z3bgmzmm75zxzib4wym

Detection of neurocognitive feigning: development of a multi-strategy assessment

S. D. Bender, R. Rogers
2004 Archives of Clinical Neuropsychology  
Using a simulation design with a manipulation check and both positive and negative incentives, two groups of simulators (Cautioned and NonCautioned) were compared with brain-injured patients and nonimpaired  ...  Neuropsychological assessments can be completely invalidated by persons successfully feigning neurocognitive impairment.  ...  With multiple strategies, Rogers (1997) suggested that cautions are not likely to reduce the effectiveness of the strategies and even have a paradoxical effect in improving detection.  ... 
doi:10.1093/arclin/19.1.49 pmid:14670379 fatcat:zzepwvej3fhazbgvrmbvyazxky

CPD – Education and Self-assessment: Functional imaging in epilepsy

M RICHARDSON
2001 Seizure  
Functional imaging plays a growing role in the clinical assessment and research investigation of patients with epilepsy.  ...  The place of these techniques in clinical evaluation and their contribution to a better neurobiological understanding of epilepsy are discussed.  ...  Hypometabolism of the left lateral temporal lobe and thalamus independently correlated with verbal memory difficulties 141 .  ... 
doi:10.1016/s1059-1311(01)90546-1 fatcat:dvozjwc2qbethbzaiyzb2evam4

The High Potential of Computer-Based Reading Assessment

Pauline Auphan, Jean Ecalle, Annie Magnan
2020 Canadian Journal of Learning and Technology  
A new computer-based reading assessment evaluating both word reading and reading comprehension processes was administered to 687 children in primary (N=400) and secondary (N=287) schools.  ...  The aim of this study is to propose advantages provided by computerized tools when assessing reading ability.  ...  She benefited from a grant of Foundation Orange. The authors thank the Masters' Degree students who participated in the data collection.  ... 
doi:10.21432/cjlt27847 doaj:be7f35980d0c4754ba1b771eb3e4492d fatcat:cngzpdglx5conomptowrv4ngiu

CPD – Education and Self-assessment: Functional imaging in epilepsy

Mark P Richardson
2001 Seizure  
Functional imaging plays a growing role in the clinical assessment and research investigation of patients with epilepsy.  ...  The place of these techniques in clinical evaluation and their contribution to a better neurobiological understanding of epilepsy are discussed.  ...  Hypometabolism of the left lateral temporal lobe and thalamus independently correlated with verbal memory difficulties 141 .  ... 
doi:10.1053/seiz.2001.0546 pmid:11407959 fatcat:hf6ntoujkneknj5jj4kqvngo44

Refining Measures for Assessing Problematic/Addictive Digital Gaming Use in Clinical and Research Settings

Kyle Faust, David Faust
2015 Behavioral Sciences  
Although adapting DSM content and strategies for measuring problematic digital gaming has proven valuable, there are some potential issues with this approach.  ...  , or in developing new and even more effective tools.  ...  For a researcher with less background in this area, this may seem like a foolish question, but many digital gamers spend significant amounts of time watching digital games.  ... 
doi:10.3390/bs5030372 pmid:26274977 pmcid:PMC4600142 fatcat:arnq4nynn5ctnpppmhphiymrie

Beam Walking to Assess Dynamic Balance in Health and Disease: A Protocol for the "BEAM" Multicenter Observational Study

Tibor Hortobágyi, Azusa Uematsu, Lianne Sanders, Reinhold Kliegl, József Tollár, Renato Moraes, Urs Granacher
2018 Gerontology  
Using beam walking distance as a measure of dynamic balance, the BEAM consortium will determine the psychometric properties, lifespan and patient reference values, the relationship with selected "dynamic  ...  Center 5 will examine patients (n = 100) diagnosed with Parkinson's disease, multiple sclerosis, stroke, and balance disorders.  ...  Funding Sources This work was supported in part by: JSPS KAKENHI grant No. 16K21320 (Japan), a startup fund from the University Medical Center Groningen (653013; The Netherlands) and the German Research  ... 
doi:10.1159/000493360 pmid:30336478 pmcid:PMC6690412 fatcat:2g677aobuzg4zflaoyi363rljq

Self-assessment of executive function and lateralization of brain pathology: What does the DEX-S profile show?
Subiektywna ocena funkcji wykonawczych a lateralizacja patologii mózgowej: co pokazuje profil DEX-S?

Ewa Szepietowska, Anna Kuzaka
2018 Psychiatria Polska  
The DEX-S Questionnaire is a tool often used in the self-report of executive difficulties.  ...  The higher sense of executive deficits in people with right hemisphere pathology may be due to the efficiency of delayed memory, and may reflect an adequate self-assessment of own competence.  ...  The confrontation with the difficulties in the distant phase of the illness might have increased the sense of deficit or, in the absence of insight, reduced it [45] .  ... 
doi:10.12740/pp/onlinefirst/85936 fatcat:rgh4aqymxfayxg7vkdajesffoa

Longitudinal study on potential neurotoxic effects of aluminium: I. Assessment of exposure and neurobehavioural performance of Al welders in the train and truck construction industry over 4 years

E. Kiesswetter, M. Schäper, M. Buchta, K. H. Schaller, B. Rossbach, H. Scherhag, W. Zschiesche, S. Letzel
2007 International Archives of Occupational and Environmental Health  
Methods The longitudinal study compared repeatedly measured exposure data and neurobehavioural data of 20, initially 44, male Al welders in the train and truck construction industry with data of a control  ...  Al welders in relation to Al exposure and neurobehavioural performance changes of a non-exposed control group.  ...  Thomas Rettig for his help with the personal air sampling.  ... 
doi:10.1007/s00420-007-0191-2 pmid:17522885 fatcat:2pm6izduozehrims6si7ssvt6i

Implications for driver assessment and rehabilitation

V.G. Wadley, K.K. Ball, D. Vance
2002 Gerontechnology  
outcome to increase elders' knowledge about the differences between 'normal' forgetfulness and more serious memory loss associated with Alzheimer's Disease (AD).  ...  It offers a means to outreach to caregivers who have concerns about memory loss in a family member to promote AD detection.  ...  Assessing the appearance of a product in the product development process together with aged user. Gerontechnology 2002; 2(1): 137.  ... 
doi:10.4017/gt.2002.02.01.067.00 fatcat:twfzlz7fvzhabgjo67lldb62qe

The assessment and management of insomnia: an update

Andrew D. Krystal, Aric A. Prather, Liza H. Ashbrook
2019 World Psychiatry  
It is a common condition associated with marked impairment in function and quality of life, psychiatric and physical morbidity, and accidents.  ...  We review this evidence base and highlight areas where more studies are needed, with the aim of providing a resource for improving the clinical management of the many patients with insomnia.  ...  For instance, sleep restriction has been shown to lower seizure thresholds, increase pain sensitivity, and precipitate mania in patients with bipolar disorder [80] [81] [82] .  ... 
doi:10.1002/wps.20674 pmid:31496087 pmcid:PMC6732697 fatcat:sqym4n2jqncijaxl6vjs6dr3iq

Assessing Cardiac Metabolism

Heinrich Taegtmeyer, Martin E. Young, Gary D. Lopaschuk, E. Dale Abel, Henri Brunengraber, Victor Darley-Usmar, Christine Des Rosiers, Robert Gerszten, Jan F. Glatz, Julian L. Griffin, Robert J. Gropler, Hermann-Georg Holzhuetter (+9 others)
2016 Circulation Research  
The main goal of this statement is to describe how the many aspects of energy transfer in the heart are assessed, keeping in mind that metabolism is the transformation of a substrate to a product.  ...  At a time when the cardiovascular research community is discovering a plethora of new molecular methods to assess cardiac metabolism, the methods remain scattered in the literature.  ...  Acknowledgments The authors wish to recognize Drs Giovanni Davogustto, Anja Karlstaedt, and Joost J Luiken for contributing to some of the sections, Roxy A.  ... 
doi:10.1161/res.0000000000000097 pmid:27012580 pmcid:PMC5130157 fatcat:7wzctwza3ndufarjswlufpc7xm
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