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Biomimicry in Bio-Manufacturing: Developments in Melt Electrospinning Writing Technology Towards Hybrid Biomanufacturing

Ferdows Afghah, Caner Dikyol, Mine Altunbek, Bahattin Koc
2019 Applied Sciences  
Subsequently, hybrid biomanufacturing strategies are presented for improved biological and mechanical properties of the manufactured porous structures.  ...  Melt electrospinning writing has been emerged as a promising technique in the field of tissue engineering, with the capability of fabricating controllable and highly ordered complex three-dimensional geometries  ...  In general, melt electrospun structures induced the expression of neural markers in the cells, and hybrid structures showed the highest expression of neural markers as compared to loop mesh and biaxial  ... 
doi:10.3390/app9173540 fatcat:aoirhcdegbg4tmrwanbsooz2rq

Design of 3D Additively Manufactured Hybrid Structures for Cranioplasty

Roberto De Santis, Teresa Russo, Julietta V. Rau, Ida Papallo, Massimo Martorelli, Antonio Gloria
2021 Materials  
, The hybrid device consisted of a 3D additive manufactured polyester porous structures infiltrated with PMMA/Cu-TCP (97.5/2.5 w/w) bone cement.  ...  A wide range of materials has been considered to repair cranial defects.  ...  (San Nicola la Strada, Caserta, Italy) for contributions in terms of software integration. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/ma14010181 pmid:33401673 fatcat:fnrdu3odprhvpmhw5b4wy5rxpu

Bone strain index as a predictor of further vertebral fracture in osteoporotic women: An artificial intelligence-based analysis

Fabio Massimo Ulivieri, Luca Rinaudo, Luca Petruccio Piodi, Carmelo Messina, Luca Maria Sconfienza, Francesco Sardanelli, Giuseppe Guglielmi, Enzo Grossi, Ezio Lanza
2021 PLoS ONE  
We assessed the predictive capacity of supervised Artificial Neural Networks (ANNs) to distinguish women who developed a further fracture from those without it, and to detect those variables providing  ...  They performed a spine X-ray to calculate spine deformity index (SDI) and a lumbar and femoral DXA scan to assess bone mineral density (BMD) and bone strain index (BSI) at baseline and after a follow-up  ...  So there is a need for other tools that can predict fracture risk in addition to BMD, for the evaluation of bone micro-architectural and textural structure [7] .  ... 
doi:10.1371/journal.pone.0245967 pmid:33556061 fatcat:w432i26nwzg2ber4ulz2emv6qa

Advanced materials for neural surface electrodes

Amelia A. Schendel, Kevin W. Eliceiri, Justin C. Williams
2014 Current opinion in solid state & materials science  
Designing electrodes for neural interfacing applications requires deep consideration of a multitude of materials factors.  ...  for neural surface electrode development.  ...  Doug Weber (douglas.weber@darpa.mil) as part of the Reliable Neural Technology Program, through the Space and Naval Warfare Systems Command (SPAWAR) Systems Center (SSC) Pacific grants No.  ... 
doi:10.1016/j.cossms.2014.09.006 pmid:26392802 pmcid:PMC4574303 fatcat:vsibbbycozax7k4mtyfcp3okqe

Review: Ex Vivo Engineering of Living Tissues with Adult Stem Cells

Bonnie Barrilleaux, Donald G. Phinney, Darwin J. Prockop, Kim C. O'connor
2006 Tissue engineering  
These rare cells are harvested from a variety of tissues, including bone marrow, adipose, skeletal muscle, and placenta, and differentiate into cells of their own lineage and in some cases atypical lineages  ...  Insight into the stem cell niche leads to the identification of matrix components, soluble factors, and physiological conditions that enhance the ex vivo amplification and differentiation of stem cells  ...  It is dedicated to the City of New Orleans-her people, her culture, and her spirit, which will never die.  ... 
doi:10.1089/ten.2006.12.3007 pmid:17518617 fatcat:osc2b4nu4rgx5eihsjgwejfup4

Electrospun nanostructured scaffolds for tissue engineering applications

Albino Martins, José V Araújo, Rui L Reis, Nuno M Neves
2007 Nanomedicine  
Those components interact together to form an interconnected nano-or micro-ranged fibrous network bounded to the membranes of cells.  ...  The micro-nanofibrous architecture was composed of electrospun nanofibers randomly deposited over a wet-spun mesh structure produced from microfibers, with a refined structure resembling nanobridges connecting  ... 
doi:10.2217/17435889.2.6.929 pmid:18095855 fatcat:wo4y2asdfbhoto2cczhhl57t2i

Differentiation of mesenchymal stem cells into neuronal cells on fetal bovine acellular dermal matrix as a tissue engineered nerve scaffold

Yuping Feng, Jiao Wang, Shixin Ling, Zhuo Li, Mingsheng Li, Qiongyi Li, Zongren Ma, Sijiu Yu
2014 Neural Regeneration Research  
The bone marrow mesenchymal stem cells grown on fetal bovine acellular dermal matrix and induced for long periods of time with neural differentiation medium differentiated into a multilayered neural network-like  ...  The purpose of this study was to assess fetal bovine acellular dermal matrix as a scaffold for supporting the differentiation of bone marrow mesenchymal stem cells into neural cells following induction  ...  to form a neural network-like structure.  ... 
doi:10.4103/1673-5374.145378 pmid:25598779 pmcid:PMC4283279 fatcat:2romvhxodbhmzhb4pivsuwegbe

Next generation bioelectronics: Advances in fabrication coupled with clever chemistries enable the effective integration of biomaterials and organic conductors

Paul J. Molino, Gordon G. Wallace
2015 APL Materials  
Herein, we provide an overview of the methods currently being employed to tailor organic conductors for bioapplications, with a focus on the development of fabrication techniques vital to the development  ...  of delivering a number of physical, chemical, and electrical stimuli.  ...  (a) Photographs of uncoated PLGA meshes (white, left) and PPy-PLGA meshes (black, right). (b) SEM micrograph of single strands of PPy-PLGA fibers. (c) SEM image of section of the PPy-PLGA meshes.  ... 
doi:10.1063/1.4905372 fatcat:zaj3mw3xozb2hpk63vthudzecm

Carbon nanotubes and their polymeric composites: the applications in tissue engineering

Boyang Huang
2020 Biomanufacturing Reviews  
The intrinsic natures of CNTs including their physical and chemical properties are first introduced, explaining the structure effects on CNTs electrical conductivity and various functionalization of CNTs  ...  In this review, we focus on the role of CNTs and their polymeric composites in tissue engineering applications, with emphasis on their usages in the nerve, cardiac and bone tissue regenerations.  ...  Acknowledgements The author wishes to acknowledge the research grant funded by the University of Manchester/King Saud University "Multi scale bioactive scaffolds for bone regeneration" project.  ... 
doi:10.1007/s40898-020-00009-x fatcat:g5hy2hnzhfavblxzixqiih5nqi

Neural Crest Lineage Segregation: a Blueprint for Periodontal Regeneration

X. Luan, S. Dangaria, Y. Ito, C.G. Walker, T. Jin, M.K. Schmidt, M.T. Galang, R. Druzinsky
2009 Journal of Dental Research  
A supplemental appendix to this article is published electronically only at  ...  scAFFoLds For PerIodoNtAL reGeNerAtIoN On their migratory path from the free regions of the neural fold to their target tissues, neural crest cells are subjected to a multitude of factors and micro-environments  ...  In the developing craniofacial region, the extracellular matrix provides both a threedimensional scaffold for the migration and anchorage of emigrating neural crest cells and a signaling micro-environment  ... 
doi:10.1177/0022034509340641 pmid:19767574 pmcid:PMC2749262 fatcat:mtisybobyzekva74lkwrtxw22q

Alignment of Cells and Extracellular Matrix Within Tissue- Engineered Substitutes [chapter]

Jean-Michel Bourget, Francois A., Lucie Germain, Maxime Guillemette, Teodor Veres
2013 Advances in Biomaterials Science and Biomedical Applications  
a laser to create a porous mesh for cardiac cells to grow.  ...  [ ] used a fibrous scaffold to guide neural cells. They used mouse neural stem cells seeded in a poly L-Lactic acid PLL" nano/micro fibrous scaffolds made by electrospinning.  ... 
doi:10.5772/54142 fatcat:ylkogxsdwrgrresxfxhmsjfu2m

STUDY OF TRABECULAR BONE IN RATS USING IMAGE PROCESSING

D Jiménez-Mendoza
2013 International Journal of Electronic Commerce Studies  
The used images were obtained by an optical microscope starting with micro slides of bone.  ...  indicators of the bone.  ...  which indicates the beginning of osteoporosis; this analysis is performed by fractals properties in the micro-structure of bone.  ... 
doi:10.7903/ijecs.1170 fatcat:wqdzdtzg2jee7axofjcvjxb5xa

Bone cancer detection using electrical impedance tomography

Nabanita Saha, Mohammad Anisur Rahaman
2021 Indonesian Journal of Electrical Engineering and Computer Science  
Electrical impedance tomography approach was proposed in this research for identifying bone cancer as this detection technique is able to distinguish between cancerous and non-cancerous cells by differentiating  ...  Bone cancer is an uncommon sort of malignancy that alludes to irregular development of tissue inside the bone, with high opportunity to spread to different pieces of the body.  ...  We require a structure for estimating the surface calculation, a mesh generator for making a cross section dependent on a superficial level data, code for calculating the finite element estimation and  ... 
doi:10.11591/ijeecs.v24.i1.pp245-252 fatcat:2s77ssblkfgk7crcuk4cnipk7m

Functional Hydrogels With Tunable Structures and Properties for Tissue Engineering Applications

Xiaomeng Li, Qingqing Sun, Qian Li, Naoki Kawazoe, Guoping Chen
2018 Frontiers in Chemistry  
As a unique type of scaffolds, hydrogels have been frequently used for TE because of their similar 3D structures to the native extracellular matrix (ECM), as well as their tunable biochemical and biophysical  ...  The strategies for tuning biophysical and biochemical properties, and structures of hydrogels are first introduced.  ...  AUTHOR CONTRIBUTIONS All authors listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication.  ... 
doi:10.3389/fchem.2018.00499 pmid:30406081 pmcid:PMC6204355 fatcat:nrb3einz3vgn5fx2ezudb4bfqu

Bone Strain Index predicts fragility fracture in osteoporotic women: an artificial intelligence-based study

Fabio Massimo Ulivieri, Luca Rinaudo, Carmelo Messina, Luca Petruccio Piodi, Davide Capra, Barbara Lupi, Camilla Meneguzzo, Luca Maria Sconfienza, Francesco Sardanelli, Andrea Giustina, Enzo Grossi
2021 European Radiology Experimental  
We applied an artificial neural network (ANN) analysis with a predictive tool (TWIST system) to select relevant input data from a list of 13 variables including BMD and BSI.  ...  All subjects performed a spine x-ray to assess VFs, together with lumbar and femoral DXA for bone mineral density (BMD) and the bone strain index (BSI) evaluation.  ...  Mohammad Rafay Malik for the English language editing and review.  ... 
doi:10.1186/s41747-021-00242-0 pmid:34664136 pmcid:PMC8523735 fatcat:vnutaivglvaydoyukoovj4fx2a
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