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Efficacy of sodium-glucose co-transporter 2 inhibitors in patients with type II diabetes

Mohammed Ibn-Mas'ud Danjuma, Shaikha Al Shokri, Arwa Ibrahim YA Al Saud, Mohamed Nabil Abdelsalam Elshafei, Haajra Fatima, Suhail Doi, Mubarak Ariyo Bidmos
2019 Medicine  
Recent systematic reviews have evaluated the efficacy of sodium-glucose co-transporter 2 inhibitors (SGLT2) inhibitors (SGLT2I) in improving glycaemic control and mortality in patients with type II diabetes  ...  We anticipate that the result of this review will provide additional insight into the ranking of the efficacy of various (SGLT2I) in type II diabetic patients especially as it relates to mortality, glycemic  ...  class regarding their efficacy in patients with type II diabetes.  ... 
doi:10.1097/md.0000000000018198 pmid:31860967 pmcid:PMC6940159 fatcat:m5ritaod55d7dotrdd6vjljd3m

Diabetic Peripheral Neuropathy in Ethiopia: A Systematic Review and Meta-Analysis

Degena Bahrey Tadesse, Gebremeskel Tukue Gebrewahd, Abrha Hailay, Woldu Aberhe, Guesh Mebrahtom, Kidane Zereabruk, Guesh Gebreayezgi, Teklewoini Mariye, Teklehaimanot Gereziher Haile, Gebreamlak Gebremedhn Gebremeskel, Gebre Teklemariam Demoz, Claudia Cardoso
2021 Journal of Diabetes Research  
Hence, this systematic review and meta-analysis provided a national prevalence of diabetic peripheral neuropathy among patients with diabetes mellitus in Ethiopia. Methods.  ...  In Ethiopia, there were no updated studies that estimate the national prevalence of DPN.  ...  Where there is missing information, the reviewers contacted the corresponding author of the study to request the missing data.  ... 
doi:10.1155/2021/5304124 pmid:33628833 pmcid:PMC7880716 fatcat:e54illxnurckhiomlm3kjjgm5y

PDB44 COST-EFFECTIVENESS OF THE USE OF ANGIOTENSIN-II-RECEPTER BLOCKERS IN PATIENTS WITH TYPE 2 DIABETES AND NEPHROPATHY IN JAPAN

S Ikeda, M Kobayashi, H Makino
2008 Value in Health  
METHODS: Productivity data (Thomson MarketScan) from a database of the commercially-insured was used to identify individuals for analysis.  ...  OBJECTIVE: To assess the cost-effectiveness of the use of telmisartan (angiotensin-II-recepter blocker, ARB) in patients with type 2 diabetes and microalbuminuria in Japan.  ...  METHODS: Productivity data (Thomson MarketScan) from a database of the commercially-insured was used to identify individuals for analysis.  ... 
doi:10.1016/s1098-3015(10)70731-2 fatcat:rhj4dnp6sbbftf4su6o5zdvyv4

Diabetes and necrotizing soft tissue infections-A prospective observational cohort study: Statistical analysis plan

A. Rosén, P. Arnell, M. B. Madsen, B. G. Nedrebø, A. Norrby-Teglund, O. Hyldegaard, V. M. dos Santos, F. Bergey, E. Saccenti, S. Skrede
2018 Acta Anaesthesiologica Scandinavica  
| Diabetes type and A1C If the amount of missing data exceeds 20%, the specific analysis will not be performed.  ...  If the frequency of missing data for a given analysis is more than 5%, the analysis will be repeated using multiple imputation based on chained equations (MICE).  ... 
doi:10.1111/aas.13130 pmid:29671865 fatcat:6u3m6htcqne4nnmzj4n7jry6hm

PDB45 CANADIAN COST UTILITY ANALYSIS COMPARING EXENATIDE VERSUS INSULIN GLARGINE IN PATIENTS WITH TYPE TWO DIABETES

D Coyle, K Coyle, WJ Valentine, JB Lee, R Kisswani, KS Boye
2008 Value in Health  
METHODS: Productivity data (Thomson MarketScan) from a database of the commercially-insured was used to identify individuals for analysis.  ...  OBJECTIVE: To assess the cost-effectiveness of the use of telmisartan (angiotensin-II-recepter blocker, ARB) in patients with type 2 diabetes and microalbuminuria in Japan.  ...  METHODS: Productivity data (Thomson MarketScan) from a database of the commercially-insured was used to identify individuals for analysis.  ... 
doi:10.1016/s1098-3015(10)70732-4 fatcat:shodveozovcnbm64xz6d4y5i7q

PDB48 LOST PRODUCTIVITY ASSOCIATED WITH TYPE I AND TYPE 2 DIABETES IN A COMMERCIALLY-INSURED POPULATION

ED Durden, B AIemayehu, F Forma
2008 Value in Health  
METHODS: Productivity data (Thomson MarketScan) from a database of the commercially-insured was used to identify individuals for analysis.  ...  OBJECTIVE: To assess the cost-effectiveness of the use of telmisartan (angiotensin-II-recepter blocker, ARB) in patients with type 2 diabetes and microalbuminuria in Japan.  ...  METHODS: Productivity data (Thomson MarketScan) from a database of the commercially-insured was used to identify individuals for analysis.  ... 
doi:10.1016/s1098-3015(10)70733-6 fatcat:zupa6n35wnhm3bq63fagha2iki

Pioglitazone and bladder cancer: a propensity score matched cohort study

Li Wei, Thomas M. MacDonald, Isla S. Mackenzie
2012 British Journal of Clinical Pharmacology  
CONCLUSION The results suggest that pioglitazone may not be significantly associated with an increased risk of bladder cancer in patients with type 2 diabetes.  ...  A propensity score matched analysis was done in a group of patients without missing baseline characteristics data.  ...  However, the propensity matched analysis in 4172 patients (2086 in each group) without missing data for the matching variables showed that there was a 59% increase in point estimate of risk of bladder  ... 
doi:10.1111/j.1365-2125.2012.04325.x pmid:22574756 pmcid:PMC3555065 fatcat:imqhqmakq5aqdow6xknnfuaoti

Competing Risks Methodology in the Evaluation of Cardiovascular and Cancer Mortality as a Consequence of Albuminuria in Type 2 Diabetes

Benjamin Feakins
2019 Figshare  
Aim: Using albuminuria in T2DM as a case study, this Thesis set out to quantify differences between standard- and competing-risks-adjusted survival analysis estimates of absolute and relative risk for  ...  To quantify differences in measures of absolute risk, cumulative risk estimates for cardiovascular and cancer mortality from standard survival analysis methods (Kaplan-Meier estimator) were compared to  ...  The failure to identify the mechanism of missingness for albuminuria meant that bias may have been present in risk estimates if data were either 'missing at random', or 'missing not at random' as a result  ... 
doi:10.6084/m9.figshare.7855712.v1 fatcat:4flauj4up5hcrdmkeyxd6j2tky

Missing in space: an evaluation of imputation methods for missing data in spatial analysis of risk factors for type II diabetes

Jannah Baker, Nicole White, Kerrie Mengersen
2014 International Journal of Health Geographics  
Methods: We present a cross-validation approach to select between three imputation methods for health survey data with correlated lifestyle covariates, using as a case study, type II diabetes mellitus  ...  However, spatial health data from surveys are often incomplete, ranging from missing data for only a few variables, to missing data for many variables.  ...  In this paper, we address this challenge by considering a case study of geographic risk factors associated with type II diabetes (DM II).  ... 
doi:10.1186/1476-072x-13-47 pmid:25410053 pmcid:PMC4287494 fatcat:rta4kgebkrgptbn3nnssgzusti

Estimating the proportion of persons with diabetes developing diabetic retinopathy in India: A systematic review and meta-analysis

G. V. S. Murthy, AT Jotheeswaran, Nukala Lovakanth, Shruthi Nadiga, Raghupathy Anchala, ClareE Gilbert
2016 Indian Journal of Endocrinology and Metabolism  
We acknowledge the support received from Arpit Awasthi, Gayathri Rao, Hemant Kumar Naik, Keerthi Reddy, Lobsang Tsering, Saurabh Gupta, Shilpy Bhat, Sreekrishna, and Susheela all of whom were involved in  ...  to identify studies that may have been missed through the electronic database search.  ...  Although age eligibility criteria differed among studies, most presented data by age group, allowing data to be pooled in the meta-analysis. About Figure 4 ].  ... 
doi:10.4103/2230-8210.179774 pmid:27144137 pmcid:PMC4847450 fatcat:g7uijdj3wjdmfcq4sgakt7vude

Diabetes and Cancer Risk: A Mendelian Randomization Study

Atsushi Goto, Taiki Yamaji, Norie Sawada, Yukihide Momozawa, Yoichiro Kamatani, Michiaki Kubo, Taichi Shimazu, Manami Inoue, Mitsuhiko Noda, Shoichiro Tsugane, Motoki Iwasaki
2019 International Journal of Cancer  
Additional analyses, using publicly available large-scale genome-wide association study data on colorectal cancer in Japan, resulted in a narrower CI (hazard ratio: 1.00; 95% CI: 0.93-1.07).  ...  With 29 known type 2 diabetes susceptibility variants, we used an inverse variance-weighted method to estimate hazard ratios for the associations of diabetes with risks of total and site-specific cancers  ...  The funders had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review and approval of the article; or the decision to submit  ... 
doi:10.1002/ijc.32310 pmid:30927373 pmcid:PMC6916579 fatcat:i7liaplkjvgj3me3vss7civm2a

All-Cause and Cardiovascular Mortality in Middle-Aged People With Type 2 Diabetes Compared With People Without Diabetes in a Large U.K. Primary Care Database

K. S. Taylor, C. J. Heneghan, A. J. Farmer, A. M. Fuller, A. I. Adler, J. K. Aronson, R. J. Stevens
2013 Diabetes Care  
RESEARCH DESIGN AND METHODSdUsing data from the General Practice Research Database, from 2004 to 2010, we conducted a cohort study of 87,098 people, 40-65 years of age at baseline, comparing 21,798 with  ...  We aimed to provide an up-to-date assessment of the relative risks associated with type 2 diabetes of all-cause and cardiovascular mortality in middle-aged people in the U.K.  ...  R.J.S. is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.  ... 
doi:10.2337/dc12-1513 pmid:23435157 pmcid:PMC3714501 fatcat:5ppq2wokyzfxtpzyqzmj64p72m

The risk of tooth loss in patients with diabetes: a systematic review and meta‐analysis

L.P.M. Weijdijk, L. Ziukaite, G.A. Van der Weijden, E. Bakker, D.E. Slot
2021 International Journal of Dental Hygiene  
The higher risk of tooth loss in DM patients was also higher when only DM type II patients or studies with a cross-sectional design were considered.  ...  A descriptive analysis demonstrated that six of these studies indicate a significantly higher risk of tooth loss in DM patients.  ...  data: T.  ... 
doi:10.1111/idh.12512 pmid:33973353 pmcid:PMC9291053 fatcat:o6uki3llbnc6bf66yxakl4jhxi

Population-calibrated multiple imputation for a binary/categorical covariate in categorical regression models

Tra My Pham, James R Carpenter, Tim P Morris, Angela M Wood, Irene Petersen
2018 Statistics in Medicine  
The method is used to impute missing ethnicity data in a type 2 diabetes prevalence case study using UK primary care electronic health records, where it results in scientifically relevant changes in inference  ...  Calibrated-δ adjustment MI represents a pragmatic approach for utilising available population-level information in a sensitivity analysis to explore potential departure from the MAR assumption.  ...  In particular, this is a cross-sectional study, which examines the association between ethnicity and the prevalence of type 2 diabetes diagnoses in a large UK primary care database in 2013.  ... 
doi:10.1002/sim.8004 pmid:30328123 fatcat:3ak7ema4izcwfoyus7lc4osxsy

Reliability audit of a regional cardiac surgery registry

Theresa Volk, Linlea Hahn, Robert Hayden, James Abel, Martin L. Puterman, G.Frank O. Tyers
1997 Journal of Thoracic and Cardiovascular Surgery  
For each case, 10 distinct fields were selected for analysis and classified as consistent, inconsistent, or rejected (data unavailable in one or other source).  ...  The purpose of this study was to compare the reliability of data contained in the Registry with data contained in hospital charts. Methods: Registry and hospital charts were compared for 480 cases.  ...  On the basis of a predicted 10% error rate in clinical databases, a sample size of 30 provides an estimate of the consistency rate per question to within 23% and an estimate of the consistency rate by  ... 
doi:10.1016/s0022-5223(97)70003-5 pmid:9434684 fatcat:zmnovf3idzdavcwqfffaqo5qvq
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