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A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography

2019 European Heart Journal  
CT angiography (CCTA).  ...  The CCTA-based radiomic profiling of coronary artery PVAT detects perivascular structural remodelling associated with coronary artery disease, beyond inflammation.  ...  ., and C.S. are founders and shareholders of Caristo Diagnostics, a CT image analysis company. M.C.W. reports a consultancy for GE Healthcare.  ... 
doi:10.1093/eurheartj/ehz592 pmid:31504423 pmcid:PMC6855141 fatcat:eg77z54jgbcxljn3do5mxwk3ri

Machine Learning for Assessment of Coronary Artery Disease in Cardiac CT: A Survey

Nils Hampe, Jelmer M Wolterink, Sanne G M van Velzen, Tim Leiner, Ivana Išgum
2019 Frontiers in Cardiovascular Medicine  
In this mini review, we present a survey of the literature on ML-based analysis of coronary artery disease in cardiac CT.  ...  However, analysis of cardiac CT scans for manifestation of coronary artery disease is time-consuming and challenging.  ...  Coronary artery centerline extraction in cardiac CT angiography using a CNN-based orientation classifier.  ... 
doi:10.3389/fcvm.2019.00172 pmid:32039237 pmcid:PMC6988816 fatcat:tsq6vf3vi5a4rjxoxzqy7xd5tu

Machine Learning and Deep Neural Networks Applications in Computed Tomography for Coronary Artery Disease and Myocardial Perfusion

Caterina B. Monti, Marina Codari, Marly van Assen, Carlo N. De Cecco, Rozemarijn Vliegenthart
2020 Journal of thoracic imaging  
Moreover, cardiac CT presents some fields wherein ML may be pivotal, such as coronary calcium scoring, CT angiography, and perfusion.  ...  Nevertheless, ML is expected to have a big impact on cardiac CT in the near future.  ...  TABLE 1 . 1 Main Applications of Machine Learning in Cardiac CT, Divided in Fields According to CAC, CT Angiography, or CTP Risk of major cardiac events: AUC of 0.79 36 combining CT angiography features  ... 
doi:10.1097/rti.0000000000000490 pmid:32195886 fatcat:unh46rzy6fa7hiq4beppuvdkfq

Research Progress of Machine Learning and Deep Learning in Intelligent Diagnosis of the Coronary Atherosclerotic Heart Disease

Haoxuan Lu, Yudong Yao, Li Wang, Jianing Yan, Shuangshuang Tu, Yanqing Xie, Wenming He, Luminita Moraru
2022 Computational and Mathematical Methods in Medicine  
models based on artificial intelligence algorithms, applications of artificial intelligence algorithms in coronary angiography, coronary CT angiography, intravascular imaging, cardiac magnetic resonance  ...  This paper presents a comprehensive review of the technical background and current state of research on the application of artificial intelligence in the diagnosis of the coronary atherosclerotic heart  ...  Acknowledgments This study was supported by the Affiliated Hospital of Medical College of Ningbo University and the Institute of Intelligent Medicine and Biomedical Engineering of Ningbo University.  ... 
doi:10.1155/2022/3016532 pmid:35516452 pmcid:PMC9064517 fatcat:nuutmmt76ndl7kcgyi6lm7ljne

On the Pathophysiology of Coronary Artery Disease

Hector Manuel Garcia-Garcia, Pedro de Araujo Gonçalves
2018 JACC Cardiovascular Imaging  
Coronary CT angiography (CTA) was initially used for the exclusion of coronary artery disease in symptomatic patients, whereas CAC established itself in risk reclassification of the subset of asymptomatic  ...  One important issue is whether the additional information for lesion location, plaque composition, detailed plaque features, noncalcified plaque burden, and their respective temporal changes provided by  ...  Coronary CT angiography (CTA) was initially used for the exclusion of coronary artery disease in symptomatic patients, whereas CAC established itself in risk reclassification of the subset of asymptomatic  ... 
doi:10.1016/j.jcmg.2017.10.030 fatcat:ktplmifzo5hlhobwct7wdscey4

Cardiac Computed Tomography for Comprehensive Coronary Assessment: Beyond Diagnosis of Anatomic Stenosis

Roosha Parikh, Apurva Patel, Bin Lu, Alpana Senapati, John Mahmarian, Su Min Chang
2020 Methodist DeBakey Cardiovascular Journal  
Cardiac computed tomography angiography (CCTA) has evolved into a versatile imaging modality that can depict atherosclerosis burden, determine functional significance of a stenotic lesion, and guide the  ...  planning of percutaneous coronary revascularization and coronary artery bypass surgery.  ...  Acknowledgements The authors thank Yan Gao, MD, and Na Zhao, MD, for their contributions of cases using CTA perfusion and FFR CT with artificial intelligence.  ... 
doi:10.14797/mdcj-16-2-77 pmid:32670467 pmcid:PMC7350823 fatcat:zfjtuqf4tjfurmmzajhplqhgwa

Future Directions in Coronary CT Angiography: CT-Fractional Flow Reserve, Plaque Vulnerability, and Quantitative Plaque Assessment

Fernando Uliana Kay, Arzu Canan, Suhny Abbara
2020 Korean Circulation Journal  
Coronary computed tomography angiography (CCTA) is a well-validated and noninvasive imaging modality for the assessment of coronary artery disease (CAD) in patients with stable ischemic heart disease and  ...  CCTA not only delineates the anatomy of the heart and coronary arteries in detail, but also allows for intra- and extraluminal imaging of coronary arteries.  ...  methods. 84) 85) Machine learning encompasses a wide range of computer-based algorithms that make predictions based on massive amounts of learning data. 11) Differently from classic statistical methods  ... 
doi:10.4070/kcj.2019.0315 pmid:31960635 pmcid:PMC7043962 fatcat:ldfwotjdcvanhmyyhe4wdjdogm

Understanding the predictive value and methods of risk assessment based on coronary computed tomographic angiography in populations with coronary artery disease: a review

Yi-ming Li, Kai-yu Jia, Yu-heng Jia, Yong Yang, Yi-jun Yao, Mao Chen, Yong Peng
2021 Precision Clinical Medicine  
Risk assessment in coronary artery disease (CAD) plays an essential role in the early identification of high-risk patients.  ...  This paper reviews conventional as well as novel diagnostic and risk assessment tools based on CCTA.  ...  Diagnostic accuracy of a deep learning approach to calculate FFR from coronary CT angiography. J Geriatr Cardiol 2019; Automatic Detection of Calcified Coronary Lesions in 3D Cardiac CT Images.  ... 
doi:10.1093/pcmedi/pbab018 pmid:35693218 pmcid:PMC8982592 fatcat:spsbhj2n4rd5rpruydkh77bmwq

Role of cardiac CT in the diagnostic evaluation and risk stratification of patients with myocardial infarction and non-obstructive coronary arteries (MINOCA): rationale and design of the MINOCA-GR study

Georgios P Rampidis, Polydoros Ν Kampaktsis, Konstantinos Kouskouras, Athanasios Samaras, Georgios Benetos, Andreas Α Giannopoulos, Theodoros Karamitsos, Alexandros Kallifatidis, Antonios Samaras, Ioannis Vogiatzis, Stavros Hadjimiltiades, Antonios Ziakas (+9 others)
2022 BMJ Open  
The role of cardiac CT angiography (CCTA) in patients with MINOCA, however, has not been well studied so far.  ...  prospective, multicentre, observational cohort study based on a national registry that will use CCTA in combination with CMR and invasive coronary angiography (ICA) to evaluate the extent and characteristics  ...  Acknowledgements We thank all the patients, investigators, and site staff for participating in this study. Rampidis GP, et al.  ... 
doi:10.1136/bmjopen-2021-054698 pmid:35110321 pmcid:PMC8811605 fatcat:pomhb5q36ndozhnmftq5gmbzsi

Relationship Between Quantitative Adverse Plaque Features From Coronary Computed Tomography Angiography and Downstream Impaired Myocardial Flow Reserve by13N-Ammonia Positron Emission TomographyCLINICAL PERSPECTIVE

Damini Dey, Mariana Diaz Zamudio, Annika Schuhbaeck, Luis Eduardo Juarez Orozco, Yuka Otaki, Heidi Gransar, Debiao Li, Guido Germano, Stephan Achenbach, Daniel S. Berman, Aloha Meave, Erick Alexanderson (+1 others)
2015 Circulation Cardiovascular Imaging  
Conclusions-Compared with stenosis, arterial NCP burden and a composite score combining quantitative stenosis and plaque burden from CT angiography significantly improves identification of downstream regional  ...  Background-We investigated the relationship of quantitative plaque features from coronary computed tomography (CT) angiography and coronary vascular dysfunction by impaired myocardial flow reserve (MFR  ...  On a per-patient basis, a modified Duke CAD index integrating the site and severity of coronary stenosis and number of coronary segments with mixed plaque were associated with decreased MFR.  ... 
doi:10.1161/circimaging.115.003255 pmid:26467104 pmcid:PMC4939903 fatcat:unoyzdahubd47miazjbubfeteu

Multimodality imaging: Bird's eye view from the European Society of Cardiology Congress 2019 Paris, August 31st–September 4th, 2019

Victoria Delgado, Antti Saraste, Marc Dweck, Chiara Bucciarelli-Ducci, Jeroen J. Bax
2019 Journal of Nuclear Cardiology  
These abstracts were integrated by one of the Editors of the Journal (JB).  ...  Experts in echocardiography (VD), nuclear imaging (AS), cardiac computed tomography (CT) (MD) and cardiovascular magnetic resonance (CMR) (CBD), have selected the abstracts in their areas of expertise  ...  Stress echocardiography had a positive predictive value of 51% for detecting [ 70% coronary artery stenosis on invasive coronary angiography and improved to 71% when carotid plaque was present.  ... 
doi:10.1007/s12350-019-01958-8 pmid:31741328 pmcid:PMC7031173 fatcat:6jcrf67zuzdmzneqehqiun7u3u

Comprehensive Modeling and Visualization of Cardiac Anatomy and Physiology from CT Imaging and Computer Simulations

Guanglei Xiong, Peng Sun, Haoyin Zhou, Seongmin Ha, Briain o Hartaigh, Quynh A. Truong, James K. Min
2017 IEEE Transactions on Visualization and Computer Graphics  
We introduce a new computer-aided diagnosis framework, which allows for comprehensive modeling and visualization of cardiac anatomy and physiology from CT imaging data and computer simulations, with a  ...  , and coronary arteries; (2) Function from CT imaging: motion modeling, strain calculation, and visualization of four heart chambers; (3) Physiology from CT imaging: quantification and visualization of  ...  Fehmi Cirak from University of Cambridge for valuable discussions on strain computation, and Anna Starikov for proofreading the manuscript.  ... 
doi:10.1109/tvcg.2016.2520946 pmid:26863663 pmcid:PMC4975682 fatcat:ced2xczizfhhrhdzmedcwbhfuy

Clinical Relevance of Coronary Computed Tomography Angiography Beyond Coronary Artery Stenosis
Klinische Relevanz der CT-Angiographie der Koronargefäße jenseits der Koronararterienstenose

Mohammed Nooruddin Meah, Michelle C. Williams
2021 RöFo. Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren (Print)  
Its capacity to detect stenotic coronary arteries safely and consistently has led to a marked decline in invasive diagnostic angiography.  ...  Recently, quantification of plaque subtypes has further improved the assessment of coronary plaque on CT.  ...  stenosis -A -> 50 % LMS -B -3-vessel ≥ 70 % on the absolute number of segments with any disease based on the 17-segment coronary tree model. ▪ 0no coronary artery disease ▪ 1coronary plaque present ▪  ... 
doi:10.1055/a-1395-7905 pmid:33772488 fatcat:6c7jzztbq5bojn7fpumbkqjgyq

Cardiac computed tomography radiomics: a narrative review of current status and future directions

Jin Shang, Yan Guo, Yue Ma, Yang Hou
2021 Quantitative Imaging in Medicine and Surgery  
However, the current interpretation of cardiac computed tomography (CT) images mainly depends on subjective and qualitative analysis.  ...  Along with advancements in cardiac CT imaging, cardiac CT radiomics is expected to provide more precise phenotyping of cardiovascular disease for patients and doctors, which can improve diagnostic, prognostic  ...  (63) extracted radiomic features from coronary artery calcium (CAC) based on non-contrast cardiac CT.  ... 
doi:10.21037/qims-21-1022 pmid:35655815 pmcid:PMC9131324 fatcat:iadaheaqkvaw3jz4xxwwxx4zwi

Artificial Intelligence in Coronary Computed Tomography Angiography: From Anatomy to Prognosis

Giuseppe Muscogiuri, Marly Van Assen, Christian Tesche, Carlo N. De Cecco, Mattia Chiesa, Stefano Scafuri, Marco Guglielmo, Andrea Baggiano, Laura Fusini, Andrea I. Guaricci, Mark G. Rabbat, Gianluca Pontone (+1 others)
2020 BioMed Research International  
Cardiac computed tomography angiography (CCTA) is widely used as a diagnostic tool for evaluation of coronary artery disease (CAD).  ...  for the detection of ischemia-inducing coronary lesions.  ...  Figure 3 : 3 Figure 3: Coronary CT angiography in a 54-year-old man without known coronary artery disease.  ... 
doi:10.1155/2020/6649410 pmid:33381570 pmcid:PMC7762640 fatcat:tjkwakhp6zaa3mmldwc2zm2lc4
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