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Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

Stéphanie M. van den Berg, Marleen H. M. de Moor, Karin J. H. Verweij, Robert F. Krueger, Michelle Luciano, Alejandro Arias Vasquez, Lindsay K. Matteson, Jaime Derringer, Tõnu Esko, Najaf Amin, Scott D. Gordon, Narelle K. Hansell (+109 others)
2015 Behavior Genetics  
DNA extractions were performed at the Wellcome Trust Clinical Research Facility in Edinburgh.  ...  We would like to acknowledge the research nurses in Orkney, the administrative team in Edinburgh and the people of Orkney. PAGES none.  ...  Exome array genotyping for GS:SFHS was funded by the Medical Research Council UK and performed at the Wellcome Trust Clinical Research Facility Genetics Core at Western General Hospital, Edinburgh, UK.  ... 
doi:10.1007/s10519-015-9735-5 pmid:26362575 pmcid:PMC4751159 fatcat:4khuyc6ta5ci5io6qjxfpw7pcu

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant inANGPTL4determining fasting TG levels

Elisabeth M van Leeuwen, Aniko Sabo, Joshua C Bis, Jennifer E Huffman, Ani Manichaikul, Albert V Smith, Mary F Feitosa, Serkalem Demissie, Peter K Joshi, Qing Duan, Jonathan Marten, Jan B van Klinken (+86 others)
2016 Journal of Medical Genetics  
Genotyping of the GS:SFHS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the UK's Medical Research Council  ...  The ERF study was further supported by ENGAGE consortium and CMSB.  ... 
doi:10.1136/jmedgenet-2015-103439 pmid:27036123 pmcid:PMC4941146 fatcat:p4u6e6rzrbcuhmtaxgcwliwdqa

Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization [article]

William J Young, Najim Lahrouchi, Aaron Isaacs, ThuyVy Duong, Luisa Foco, Farah Ahmed, Jennifer A Brody, Reem Salman, Raymond Noordam, Jan-Walter Benjamins, Jeffrey Haessler, Leo-Pekka Lyytikäinen (+154 others)
2021 medRxiv   pre-print
Acknowledgements All individual and study acknowledgements can be found in Supplementary Note 4, and funding information in Supplementary Note 5.  ...  Most (87%) participants were born in Scotland and 96% in the UK or Ireland.  ...  The 27-year follow-up study was conducted in 2007 (ages 30-45 years) with 2,204 participants.  ... 
doi:10.1101/2021.11.04.21265866 fatcat:wxscvfzktrardlboa5hjvoxche

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

Yurii S Aulchenko, Samuli Ripatti, Ida Lindqvist, Dorret Boomsma, Iris M Heid, Peter P Pramstaller, Brenda W J H Penninx, A Cecile J W Janssens, James F Wilson, Tim Spector, Nicholas G Martin, Nancy L Pedersen (+45 others)
2008 Nature Genetics  
Thomas' twin cohort Illumina 318K UK 1,129 0 0 0 0 0 0 0 5.4 (1.2) UK-TWIN, monozygotic twins of the St.  ...  The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013)/grant agreement HEALTH-F4-2007-201413 by the European Commission under  ... 
doi:10.1038/ng.269 pmid:19060911 pmcid:PMC2687074 fatcat:l6ne3juzovhtznkd33kzcikboi

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Nathan A. Bihlmeyer, Jennifer A. Brody, Albert Vernon Smith, Helen R. Warren, Honghuang Lin, Aaron Isaacs, Ching-Ti Liu, Jonathan Marten, Farid Radmanesh, Leanne M. Hall, Niels Grarup, Hao Mei (+88 others)
2018 Circulation Genomic and Precision Medicine  
Genotyping of the GS:SFHS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK  ...  Participants were recruited across Scotland, with some family members from further afield, from 2006 -2011. Most (87%) participants were born in Scotland and 96% in the UK or Ireland.  ... 
doi:10.1161/circgen.117.001758 pmid:29874175 pmcid:PMC5992491 fatcat:wgmptzckq5abzioihwwlo2rphe

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2with serum creatinine level

Cristian Pattaro, Alessandro De Grandi, Veronique Vitart, Caroline Hayward, Andre Franke, Yurii S Aulchenko, Asa Johansson, Sarah H Wild, Scott A Melville, Aaron Isaacs, Ozren Polasek, David Ellinghaus (+21 others)
2010 BMC Medical Genetics  
The ERF study was supported by grants from the NWO, Erasmus MC and the Centre for Medical Systems Biology (CMSB).  ...  DNA extractions were performed at the Wellcome Trust Clinical Research Facility in Edinburgh.  ... 
doi:10.1186/1471-2350-11-41 pmid:20222955 pmcid:PMC2848223 fatcat:oavelhgzivgmpg6f6ygvd7mh34

Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

A. Dehghan, J. Dupuis, M. Barbalic, J. C. Bis, G. Eiriksdottir, C. Lu, N. Pellikka, H. Wallaschofski, J. Kettunen, P. Henneman, J. Baumert, D. P. Strachan (+102 others)
2011 Circulation  
, UK for samples management, and the Wellcome Trust Clinical Research Facility in Edinburgh, UK for performing the initial SNP genotyping.  ...  agreement HEALTH-F2-2008-201865-GEFOS and (FP7/2007-2013), ENGAGE project grant agreement HEALTH-F4-2007-201413 and the FP-5 GenomEUtwin Project (QLG2-CT-2002-01254).  ... 
doi:10.1161/circulationaha.110.948570 pmid:21300955 pmcid:PMC3147232 fatcat:74fydaeoazfdjl7ugsd2tn4bri

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Vasiliki Lagou, Reedik Mägi, Jouke- Jan Hottenga, Harald Grallert, John R. B. Perry, Nabila Bouatia-Naji, Letizia Marullo, Denis Rybin, Rick Jansen, Josine L. Min, Antigone S. Dimas, Anna Ulrich (+193 others)
2021
DNA extractions were performed at the Wellcome Trust Clinical Research Facility in Edinburgh.  ...  We would like to acknowledge the invaluable contributions of Lorraine Anderson, the research nurses in Orkney, and the administrative team in Edinburgh.  ...  Genotyping was supported by a grant from the Chief Scientist Office, Scotland and performed at the Wellcome Trust Clinical Research Facility in Edinburgh.  ... 
doi:10.17863/cam.62859 fatcat:lbmqtkrldbh2for3ldeopsyahi

New loci associated with kidney function and chronic kidney disease

Anna Köttgen, Cristian Pattaro, Carsten A Böger, Christian Fuchsberger, Matthias Olden, Nicole L Glazer, Afshin Parsa, Xiaoyi Gao, Qiong Yang, Albert V Smith, Jeffrey R O'Connell, Man Li (+120 others)
2010 Nature Genetics  
register stratified by gender and 5 year age groups.  ...  (CMSB). We are grateful to all study participants and their relatives, general practitioners and neurologists for their contributions and to P. Veraart for her help in genealogy, J.  ...  The research of Inga Prokopenko and Reedik Magi is funded in part through the European Community's Seventh Framework Programme (FP7/2007-2013), ENGAGE project, grant agreement HEALTH-F4-2007-201413.  ... 
doi:10.1038/ng.568 pmid:20383146 pmcid:PMC2997674 fatcat:nhm6zxyy3zhctjs6yejr5pxizu

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Georg B Ehret, Teresa Ferreira, Daniel I Chasman, Anne U Jackson, Ellen M Schmidt, Toby Johnson, Gudmar Thorleifsson, Jian'an Luan, Louise A Donnelly, Stavroula Kanoni, Ann-Kristin Petersen, Vasyl Pihur (+301 others)
2016 Nature Genetics  
Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, EH4 2XU 7 Scotland, UK 8 129.  ...  For these SNPs, we performed a stage 5 meta-analysis combining 19 the association summary statistics from stage 4 and UK Biobank, in a total of up to 342,415 individuals 20 (Supplementary Table 5 ). 21  ... 
doi:10.1038/ng.3667 pmid:27618452 pmcid:PMC5042863 fatcat:uqpr7mdmvfcabblnzpf7qczbsy

Multiethnic Exome-Wide Association Study of Subclinical AtherosclerosisCLINICAL PERSPECTIVE

Pradeep Natarajan, Joshua C. Bis, Lawrence F. Bielak, Amanda J. Cox, Marcus Dörr, Mary F. Feitosa, Nora Franceschini, Xiuqing Guo, Shih-Jen Hwang, Aaron Isaacs, Min A Jhun, Maryam Kavousi (+88 others)
2016 Circulation: Cardiovascular Genetics  
Facility Genetics Core at Western General Hospital, Edinburgh, UK.  ...  They were all Caucasian, community-dwelling, and almost all lived in the Lothian region (Edinburgh city and surrounding area) of Scotland.  ... 
doi:10.1161/circgenetics.116.001572 pmid:27872105 pmcid:PMC5418659 fatcat:gdd7rb3nc5hg5bpvo2cf36iq5i

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Robert A Scott, Vasiliki Lagou, Ryan P Welch, Eleanor Wheeler, May E Montasser, Jian'an Luan, Reedik Mägi, Rona J Strawbridge, Emil Rehnberg, Stefan Gustafsson, Stavroula Kanoni, Laura J Rasmussen-Torvik (+202 others)
2012 Nature Genetics  
Genotyping was supported by a grant from the Chief Scientist Office, Scotland, and was performed at the Wellcome Trust Clinical Research Facility in Edinburgh.  ...  The Ely Study was funded by the MRC (MC_U106179471) and Diabetes UK.  ... 
doi:10.1038/ng.2385 pmid:22885924 pmcid:PMC3433394 fatcat:nn2yakrydbf7pdme6dvi6a4pwq

Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRICLINICAL PERSPECTIVE

Benjamin F.J. Verhaaren, Stéphanie Debette, Joshua C. Bis, Jennifer A. Smith, M. Kamran Ikram, Hieab H. Adams, Ashley H. Beecham, Kumar B. Rajan, Lorna M. Lopez, Sandra Barral, Mark A. van Buchem, Jeroen van der Grond (+90 others)
2015 Circulation: Cardiovascular Genetics  
The ERF study was further supported by ENGAGE consortium and CMSB.  ...  , 7 A total of 2007 participants were randomly selected from the official community register stratified by gender and 5 year age groups.  ... 
doi:10.1161/circgenetics.114.000858 pmid:25663218 pmcid:PMC4427240 fatcat:k7cdljyqnnhnrnelnsqkpkbfn4

Dagstuhl Reports, Volume 4, Issue 11, November 2014, Complete Issue [article]

2015
Therefore, various types of community networks (e. g., Guifi in Spain, Tegola in Scotland, Cybermoor in Cumbria, UK) and their characteristics are also discussed separately in this report.  ...  Available as: http://arxiv.org/abs/0704.1908. 5 Erban, R. and Chapman, J., 2007. Reactive boundary conditions for stochastic simulations of reaction-di usion processes.  ... 
doi:10.4230/dagrep.4.11 fatcat:zzps76cx7rfldla5z5dikvsqbe