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1ML – core and modules united (F-ing first-class modules)

Andreas Rossberg
2015 Proceedings of the 20th ACM SIGPLAN International Conference on Functional Programming - ICFP 2015  
Yet, 1ML does not require dependent types, and its type structure is expressible in terms of plain System Fω, in a minor variation of our F-ing modules approach.  ...  Language extensions allowing modules to be packaged up as first-class values have been proposed and implemented in different variations.  ...  Acknowledgements I thank Scott Kilpatrick, Claudio Russo, Gabriel Scherer, and the anonymous reviewers for their careful and helpful comments.  ... 
doi:10.1145/2784731.2784738 dblp:conf/icfp/Rossberg15 fatcat:w66ror5lcbad3ahgana26jnh2m

A unique data analysis framework and open source benchmark data set for the analysis of comprehensive two-dimensional gas chromatography software

Benedikt A. Weggler, Lena M. Dubois, Nadine Gawlitta, Thomas Gröger, John Moncur, Luigi Mondello, Steven Reichenbach, Peter Tranchida, Zhijun Zhao, Ralf Zimmermann, Mariosimone Zoccali, Jean-François Focant
2020 Journal of Chromatography A  
First, to propose a data analysis framework and second to propose an open-source dataset for benchmarking software options and their specificities.  ...  Thus, allowing for an unanimous and comprehensive evaluation of GC × GC software. Thereby, the benchmark data includes a set of standard compound measurements and a set of chocolate aroma profiles.  ...  Modulation of the first dimensions effluent was obtained using a solid-state modulator (SSM 1800 -J&X Technologies, Shanghai, China) equipped with a 1.05m GsBP-1 (0.25 mm/0.1 μm) trapping column (GS-Tek  ... 
doi:10.1016/j.chroma.2020.461721 pmid:33246680 fatcat:kplf57mxqbfazazrbvqfciiogq

Chaperone activity of tobacco HSP18, a small heat-shock protein, is inhibited by ATP

Petr Smykal, Jiri Masin, Ivan Hrdy, Ivo Konopasek, Viktor Zarsky
2000 The Plant Journal  
Chen Nicholl, .D. and Quinlan, R.A. (1994 rystallins modules intermediate f 4, 945-953 — L., Scharf, K.D. and Neumann, D shoc granuies are formed fron Yoo, S.H., Albanesi, J.P. and Jameson, D.M eotide  ...  ., Buchner, J. and Goloubinoff, P substrates and can maintain a substrate in a f Tt si t t pr f f a state.  ... 
doi:10.1046/j.1365-313x.2000.00837.x pmid:10998182 fatcat:2zhdel4ikzeglkzotnuyovk22m

Dynamics of anteroposterior axis establishment in a mammalian embryo-like system [article]

Kerim Anlaş, Nicola Gritti, David Oriola, Krisztina Arató, Fumio Nakaki, Jia Le Lim, James Sharpe, Vikas Trivedi
2021 bioRxiv   pre-print
In the mammalian embryo, specification of the anteroposterior (AP) axis demarcates one of the first steps of body plan formation.  ...  We further conduct single-cell (sc) RNA sequencing of gastruloids at early stages to identify incipient molecular signatures of germ layer commitment and differences between Bra/T+ and Bra/T- populations  ...  While the core area of the agreggates appears to exhibit elevated F-actin signal across timepoints, there are no clear changes in cell shape or size.  ... 
doi:10.1101/2021.02.24.432766 fatcat:sg3d3yal4ffi5f2vks4k3eg5km

The Transcriptome-wide Landscape and Modalities of EJC Binding in Adult Drosophila

Ales Obrdlik, Gen Lin, Nejc Haberman, Jernej Ule, Anne Ephrussi
2019 Cell Reports  
Moreover, EJC occupancy is highest at junctions adjacent to strong splice sites, CG-rich hexamers, and RNA structures.  ...  Highly occupied mRNAs tend to be maternally localized and derive from genes involved in differentiation or development.  ...  After finalization of the last washing step IP beads were resuspended in 1ml PBS and completed with 0.2 units of RNaseI.  ... 
doi:10.1016/j.celrep.2019.06.088 pmid:31365866 fatcat:yz5hspjmm5d57bo2i7sc6btpwe

Modern Applied Science, Vol. 3, No. 4, April 2009, all in one file

Editor MAS
2009 Modern Applied Science  
Top height and basal area were incorporated into the base model.  ...  Comparison of the base and expanded models showed that, although the goodness-of-fit measures on the modelling data were improved with the inclusion of top height and basal area, the predictive accuracy  ...  Special thanks are given to our industry partners, and to Mr. R. Briand, Dr. W.R. Dempster and Mr. D.J. Morgan for their help and contributions to this project. The constructive suggestions from Dr.  ... 
doi:10.5539/mas.v3n4p0 fatcat:zy26n4n5wjhwjktpcw4jtbs7fm

Chiral Brønsted Acid-Catalyzed Enantioselective α-Amidoalkylation Reactions: A Joint Experimental and Predictive Study

Eider Aranzamendi, Sonia Arrasate, Nuria Sotomayor, Humberto González-Díaz, Esther Lete
2016 ChemistryOpen  
Supporting Information and the ORCID identification number(s) for the author(s) of this article can be found underh ttp://dx.  ...  As in the previousc ase, we first selected as eries of well-knowns ubstrates and catalysts from the literature.  ...  The reaction was quenched by addition of HCl (1 m,1mL) and then satuarated NaHCO 3 (1 mL). The aqueous phase was extracted with CH 2 Cl 2 (3 10 mL).  ... 
doi:10.1002/open.201600120 pmid:28032023 pmcid:PMC5167290 fatcat:saal5vsserdyvg7skunpstwtbq

MicroRNAs, the DNA damage response and cancer

Maikel D. Wouters, Dik C. van Gent, Jan H.J. Hoeijmakers, Joris Pothof
2011 Mutation research  
Acknowledgements Acknowledgements Finally, written last, but read first by all.  ...  Acknowledgements We thank Sabine van Steenbergen-Langeveld for performing measurements of IL6/IL8 in medium supernatant and Christel Kockx for printing microarray slides and providing technical assistance  ...  F. Marteijn 1 , J.  ... 
doi:10.1016/j.mrfmmm.2011.03.012 pmid:21477600 fatcat:f3qgjrbffvgmfkjld7jkbxtf2i

[Back cover]

1975 IEEE Transactions on Power Apparatus and Systems  
His research interests are in solid state electronics, direct energy conversion, and field modulated power generation.  ...  He published over 20 papers in professional journals and is listed in Who's Who in the East and the Dictionary of International Biographies.  ...  With the second method, consumption is broken down into homogeneous sectors, for which the modulation factors and the extrapolation technique, applied to the different consumption classes, evolution of  ... 
doi:10.1109/t-pas.1975.32070 fatcat:zccnrdbfanb2xj2ccdjlnb5lga

Functional and Anatomical Specificity in a Higher Olfactory Centre [article]

Shahar Frechter, Alexander S. Bates, Sina Tootoonian, Michael-John Dolan, James D. Manton, Arian Jamasb, Johannes Kohl, Davi Bock, Gregory S.X.E. Jefferis
2018 bioRxiv   pre-print
We find that the lateral horn contains >1300 neurons and by combining genetic, anatomical and functional criteria, we identify >150 cell types.  ...  We have carried out a comprehensive anatomical analysis of the Drosophila lateral horn and identified genetic driver lines targeting many LHNs.  ...  The olfactory systems of mammals and insects have many 50 similarities, including the presence of glomerular units in the first olfactory processing center.  ... 
doi:10.1101/336982 fatcat:j5fwv7uxhnd2disgwam7oflkae

Lattice Shrinkage by Incorporation of Recombinant Starmaker‐Like Protein within Bioinspired Calcium Carbonate Crystals

Mirosława Różycka, Ismael Coronado, Katarzyna Brach, Joanna Olesiak‐Bańska, Marek Samoć, Mirosław Zarębski, Jerzy Dobrucki, Maciej Ptak, Eva Weber, Iryna Polishchuk, Boaz Pokroy, Jarosław Stolarski (+1 others)
2019 Chemistry - A European Journal  
in biomineral and bioinspired crystals) of the crystal lattice volume, which is described herein, for the first time, for bioinspired mineralization.  ...  Ar ing pattern was observed in crystals grown for 48 h; this was composed of ap roteinenrichedr egion flankedb yp rotein-depleted regions.I tc an be explained as ar esulto ft he Ostwald-like ripeningp  ...  of Wroclaw University of Science and Te chnology.  ... 
doi:10.1002/chem.201903711 fatcat:kn4bmkzpt5hfvjxtl23bp6shsm

Novel strategies for enhancing tissue integration in cartilage repair

L.C. Davies, B. Caterson, V.C. Duance
2008 International journal of experimental pathology (Print)  
Class III SLRPs This class consists of the proteoglycans epiphycan and osteoglycin.  ...  Class I SLRPs Class n SLRPs This group is further divided into 2 subfamilies.  ...  ix 3 PBS and Tween 20™ A lx working concentration o f PBS was made up and the pH adjusted as previously described.  ... 
doi:10.1111/j.0959-9673.2004.369aa.x fatcat:2pprov56hvbp7knlhrk5kcj4s4

P5-12-01: Aromatase Inhibitor Specific Metastasis Is Driven by the Steroid Receptor Coactivator SRC-1

SM Theissen, J McBryan, C Byrne, E Hughes, S Cocchiglia, AD Hill, LS Young
2011 Cancer Research  
Acknowledgments The authors thank Lance Hudson and Fiona Bane for their technical expertise.  ...  The supernatant was discarded and the agarose was washed on a ro to r fo r 5 m inutes each w ith 1ml o f the follow ing buffers: low salt im m une complex wash buffer, high salt immune complex wash buffer  ...  therapy (sequencing o f tam oxifen before or a fte r an aromatase inhibitor during the first five years) and extended adjuvant therapy (aromatase in hibitor therapy follow ing five years o f tam oxifen  ... 
doi:10.1158/0008-5472.sabcs11-p5-12-01 fatcat:jxcxtpctezf57h2bd7jrb6zksq

Conservation of Specificity in Two Low-Specificity Proteins

Lucas C. Wheeler, Jeremy A. Anderson, Anneliese J. Morrison, Caitlyn E. Wong, Michael J. Harms
2017 Biochemistry  
8 S100 proteins bind linear peptide regions of target proteins and modulate their ac-9 tivity.  ...  We first used isothermal titration calorimetry 15 to study the binding of a collection of peptides with diverse sequence, hydrophobic-16 ity, and charge to human S100A5 and S100A6.  ...  log-likelihood 61 units higher than the next-best model.  ... 
doi:10.1021/acs.biochem.7b01086 pmid:29240404 pmcid:PMC5995566 fatcat:dy57czd2obgrffrpjsybibpudu

Conservation of specificity in two low-specificity proteins [article]

Lucas C Wheeler, Jeremy A Anderson, Annelise J Morrison, Caitlyn E Wong, Michael J Harms
2017 bioRxiv   pre-print
S100 proteins bind linear peptide regions of target proteins and modulate their activity.  ...  We first used isothermal titration calorimetry to study the binding of a collection of peptides with diverse sequence, hydrophobicity, and charge to human S100A5 and S100A6.  ...  log-likelihood 61 units higher than the next-best model.  ... 
doi:10.1101/207324 fatcat:zmolnjx2rbc27i6b2fokmvtwrm
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