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Tangutidines A–C, Three Amphoteric Diterpene Alkaloids from Aconitum tanguticum
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Hao-Yi Li,
Bing-Chao Yan,
Li-Xin Wei,
Han-Dong Sun,
Jianxin Pu
Abstract
<jats:title>Abstract</jats:title>Three new diterpene alkaloids, tangutidines A–C (<jats:bold>1</jats:bold>–<jats:bold>3</jats:bold>), and four known alkaloids (<jats:bold>4</jats:bold>–<jats:bold>7</jats:bold>) were isolated from the whole plant of <jats:italic>Aconitum tanguticum</jats:italic>, from which amphoteric diterpene alkaloids (<jats:bold>1</jats:bold>–<jats:bold>3</jats:bold>) were obtained for the first time. The structures of <jats:bold>1</jats:bold>–<jats:bold>3</jats:bold> were elucidated by detailed interpretation of spectroscopic data, including MS and NMR data. All of them were evaluated for their cytotoxic activities.
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