@misc{guryev_schuster_tsogoeva_2022, 
  title={Light-driven catalyst-free access to phthalazines: Merging two metal-free domino reactions in one-pot}, 
  DOI={10.26434/chemrxiv-2022-j4xvz}, 
  abstractNote={<jats:p>We report the development of an unprecedented metal-free four-step one-pot synthetic strategy to access high-value functionalized phthalazines using o-methyl benzophenones as starting compounds. Combination of a light-mediated enolization of o-methyl benzophenones/Diels-Alder reaction domino process with a subsequent deprotection/aromatization domino reaction in one-pot leads to sustainable and efficient organic synthesis. The tangible advantages, i.e. absence of catalysts or additives, utilization of commercially available and/or easily accessible substrates, mild reaction conditions, simplicity, and single work-up procedure, make this combined process highly appealing for the direct construction of various 1-aryl-phthalazines.</jats:p>}, 
  publisher={American Chemical Society (ACS)}, 
  author={Guryev, Anton and Schuster, Florian and Tsogoeva, Svetlana}, 
  year={2022}, 
  month={Jan}
  }