Biochemical and cytochemical changes of alpha-esterases activity in long-term oral contraceptive users
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N El-dardiry,
H El-kabarity,
S El-sahwi,
A El-fazzari,
L Kira,
M Rizk,
S M El-sewedy,
M H Mostafa,
G Abdel-aal,
A A Saad
1980 Volume 16, Issue 2, p353-8
Abstract
The alpha-esterases activity was measured in the serum and vaginal fluid of 39 women who used (OCs) oral contraceptives for long periods of time (12-15 years). The results were compared with the activity of 30 control fertile females who did not take any OCs. The alpha-esterases activity was measured by cytochemical and modified simple reproducible biochemical methods. The biochemical study revealed that serum alpha-esterases activity is not affected either by long-term use of OCs or by different types of cervical infections. On the other hand, the cytochemical and biochemical results show that there is a significant increase in the activity of vaginal alpha-esterases in pill users accompanied with cervicitis. The increase in vaginal alpha-esterases activity may shed light on the possible relationship between the activity of alpha-esterases and malignancy.
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