Antimicrobial Susceptibility Pattern of Klebsiella pneumonia from Various Clinical and environmental Samples in Diwaniyah hospitals. release_m7cfndwjg5b6fnq6wftmp7vhvy

by Zahraa Ahmed, Firas Srhan Abd AlMayahi

Published in Al-Qadisiyah Journal Of Pure Science by Al-Qadisiyah Journal of Pure Science.

2021   Volume 26

Abstract

            Antibiotic resistance in bacteria has become a worrying phenomenon in today's world,    K. pneumoniae is a member of the Enterobacteriaceae family, which causes nosocomial infections as  an opportunistic pathogen but inherently harbored as a part of the natural human microbiota this study aims to inform the sensitivity of bacteria to different antibiotics commonly used in the treatment against K. pneumoniae strains isolated from different infection sites and hospital environmental samples. Samples were collected from different sources (n = 886) were recorded from Diwaniyah hospitals during the period from August 2019 to January 2020, Among the 275 isolates positive for bacterial culture, only 70 isolates (40%) were identified as K.pneumoniae by standard  microbiological techniques and antibiotic susceptibility testing was done by Kirby-Bauer disc diffusion testing to 29 antibiotics using the tablet diffusion method according to CLSI 2020,  The results susceptibility testing showed that frequency resistance of K. pneumoniae isolates to Pipercillin and Amoxicillin/ clavulanic acid was (100 %), Cefuroxime )97.14%) Cefoxitin (50%), Cefotaxime (74.28%), ceftriaxone (84.28%), aztreonam (52.85%), ceftazidime (81.42%), Tetracycline (70%), Nitrofurantoin (61.42%), Amikacin (57.14%), ciprofloxacin (50%). Also, the results showed the highest frequency of susceptibility            among  K.pneumoniae was associated withOfloxacin(78.57%), Netilmicin(74.28%), Gentamicin(75.71%), Meropenem(68.57%), Trimethoprim-Sulfamethoxazole(64.28%),  Levofloxacin(72.85%).
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