A facile method for monitoring sphingomyelin synthase activity in HeLa cells using liquid chromatography/mass spectrometry
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by
Punith M. Sundaraswamy,
Jayashankar Jayaprakash,
Yusuke Minami,
Siddabasave Gowda B. Gowda,
Hiroyuki Takatsu,
Divyavani Gowda,
Hye-Won Shin,
Shu-Ping Hui
Abstract
Sphingomyelin synthase (SMS) is a sphingolipid-metabolizing enzyme involved in the de novo synthesis of sphingomyelin (SM) from ceramide (Cer). Recent studies have indicated that SMS is a key therapeutic target...
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