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POLYMORPHISM OF TWO LIG4 GENETIC MARKERS IN THE INDIGENOUS AND MIGRANT POPULATION OF KEMEROVO REGION
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by
A. N. Volkov,
A. I. Martinyuk,
A. V. Larionov,
D. K. Shihkova,
V. I. Minina,
A. A. Timopheeva,
V. G. Druzhinin
Abstract
The population genetic characteristics of two LIG4 polymorphic markers were examined in the indigenous (the Shors) and migrant (the Russians) population of Kemerovo region. The frequencies of genetic variants of Ala3Val polymorphism did not differ significantly between the two groups. At the same time a significant difference of the genotypes and allele polymorphism of Thr9Ile distributions between the ethnic cohorts was revealed. Minor allele Ile frequency among the representatives of the migrant population was almost three times as high as that of theindigenous ethnic group.
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