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Developing in vitro Assays to Transform Gastrointestinal Safety Assessment: Potential for Microphysiological Systems
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by
Matt Peters,
Allison Choy,
Carmen Pin,
Derek Leishmann,
Annie Moisan,
Lorna C Ewart,
Peggy Guzzie-Peck,
Radhakrishna Sura,
Douglas Keller,
Clay W Scott,
Kyle Kolaja
Abstract
Drug-induced gastrointestinal toxicities (DI-GITs) are among the most common adverse events in clinical trials. High prevalence of DI-GIT has persisted among new drugs due in part to the lack of...
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