@article{p. jyothishna_a. madhusudhan reddy_2024, 
  title={Formulation And In Vitro Evaluation Of Dalfampridine Sustained Release Tablets By Using Various Polymers}, 
  volume={12}, 
  DOI={10.61096/ijamscr.v12.iss4.2024.562-573}, 
  abstractNote={<jats:p>In present investigation the sustained release tablets of Dalfampridine was formulated to study effect various natural polymers of Tragacanth, Acacia gum and Xanthan gum. The model is based on a novel dosage form designed to deliver a drug into the gastrointestinal tract in a controlled manner. Matrix tablets were prepared by direct compression method. As a pre-requisite and part of pre-formulation studies, drug along with selected excipients and as optimized formulation was subjected to FT-IR studies. It was found that no interaction among excipients occurred, as no extra peaks obtained. Tablets were evaluated for various IP-QC tests like hardness, friability, content uniformity and in-vitro drug release by USP paddle apparatus. It was found that the release of drug D3 formulation showed 99.83% the formulation was gave the better release than other formulations. In these nine formulations D3 formulation was showing highest release following Peppas release kinetics.</jats:p>}, 
  number={4}, 
  publisher={Dr Sriram Publications}, 
  author={P. Jyothishna and A. Madhusudhan Reddy}, 
  year={2024}, 
  month={Nov}
  }